4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide

C120H107F19N24O6 — CID 158257585

About 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide

4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide (PubChem CID 158257585) has the molecular formula C120H107F19N24O6 and a molecular weight of 2342.30 g/mol. Its IUPAC name is 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide
• PubChem CID: 158257585
• Molecular Formula: C120H107F19N24O6
• Molecular Weight: 2342.30 g/mol
• Exact Mass: 2340.85
• IUPAC Name: 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide
• SMILES: C=C1Cc2ccc(Nc3cc(Nc4cc(F)c(F)cc4C(=O)NC)c(C(F)(F)F)cn3)cc2C1.C=C1Cc2ccc(Nc3cc(Nc4cccnc4C(=O)N(C)C)c(C(F)(F)F)cn3)cc2C1.C=C1Cc2ccc(Nc3cc(Nc4ccncc4C(=O)NC)c(C(F)(F)F)cn3)cc2C1.C=C1Cc2ccc(Nc3cc(Nc4cnccc4C(=O)NC)c(C(F)(F)F)cn3)cc2C1.CNC(=O)c1cc(F)c(F)cc1Nc1cc(Nc2ccc(N3CCCCC3)cc2OC)ncc1C(F)(F)F
• InChI: InChI=1S/C26H26F5N5O2.C24H19F5N4O.C24H22F3N5O.2C23H20F3N5O/c1-32-25(37)16-11-18(27)19(28)12-21(16)34-22-13-24(33-14-17(22)26(29,30)31)35-20-7-6-15(10-23(20)38-2)36-8-4-3-5-9-36;1-12-5-13-3-4-15(7-14(13)6-12)32-22-10-21(17(11-31-22)24(27,28)29)33-20-9-19(26)18(25)8-16(20)23(34)30-2;1-14-9-15-6-7-17(11-16(15)10-14)30-21-12-20(18(13-29-21)24(25,26)27)31-19-5-4-8-28-22(19)23(33)32(2)3;1-13-7-14-3-4-16(9-15(14)8-13)30-21-10-20(18(12-29-21)23(24,25)26)31-19-5-6-28-11-17(19)22(32)27-2;1-13-7-14-3-4-16(9-15(14)8-13)30-21-10-19(18(11-29-21)23(24,25)26)31-20-12-28-6-5-17(20)22(32)27-2/h6-7,10-14H,3-5,8-9H2,1-2H3,(H,32,37)(H2,33,34,35);3-4,7-11H,1,5-6H2,2H3,(H,30,34)(H2,31,32,33);4-8,11-13H,1,9-10H2,2-3H3,(H2,29,30,31);3-6,9-12H,1,7-8H2,2H3,(H,27,32)(H2,28,29,30,31);3-6,9-12H,1,7-8H2,2H3,(H,27,32)(H2,29,30,31)
• InChIKey: GHLYAKQYLZSDPL-UHFFFAOYSA-N
• XLogP: 27.44
• TPSA: 372.60 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 25
• Rotatable Bonds: 27
• Heavy Atoms: 169
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2342.30
LogP ≤ 5	27.44
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	25

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'isolated_alkene', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide?

The IUPAC name of 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide (CID 158257585) is 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide.

What is the SMILES notation for 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide?

The canonical SMILES for 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide is C=C1Cc2ccc(Nc3cc(Nc4cc(F)c(F)cc4C(=O)NC)c(C(F)(F)F)cn3)cc2C1.C=C1Cc2ccc(Nc3cc(Nc4cccnc4C(=O)N(C)C)c(C(F)(F)F)cn3)cc2C1.C=C1Cc2ccc(Nc3cc(Nc4ccncc4C(=O)NC)c(C(F)(F)F)cn3)cc2C1.C=C1Cc2ccc(Nc3cc(Nc4cnccc4C(=O)NC)c(C(F)(F)F)cn3)cc2C1.CNC(=O)c1cc(F)c(F)cc1Nc1cc(Nc2ccc(N3CCCCC3)cc2OC)ncc1C(F)(F)F.

What is the InChIKey of 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide?

The InChIKey is GHLYAKQYLZSDPL-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H26F5N5O2.C24H19F5N4O.C24H22F3N5O.2C23H20F3N5O/c1-32-25(37)16-11-18(27)19(28)12-21(16)34-22-13-24(33-14-17(22)26(29,30)31)35-20-7-6-15(10-23(20)38-2)36-8-4-3-5-9-36;1-12-5-13-3-4-15(7-14(13)6-12)32-22-10-21(17(11-31-22)24(27,28)29)33-20-9-19(26)18(25)8-16(20)23(34)30-2;1-14-9-15-6-7-17(11-16(15)10-14)30-21-12-20(18(13-29-21)24(25,26)27)31-19-5-4-8-28-22(19)23(33)32(2)3;1-13-7-14-3-4-16(9-15(14)8-13)30-21-10-20(18(12-29-21)23(24,25)26)31-19-5-6-28-11-17(19)22(32)27-2;1-13-7-14-3-4-16(9-15(14)8-13)30-21-10-19(18(11-29-21)23(24,25)26)31-20-12-28-6-5-17(20)22(32)27-2/h6-7,10-14H,3-5,8-9H2,1-2H3,(H,32,37)(H2,33,34,35);3-4,7-11H,1,5-6H2,2H3,(H,30,34)(H2,31,32,33);4-8,11-13H,1,9-10H2,2-3H3,(H2,29,30,31);3-6,9-12H,1,7-8H2,2H3,(H,27,32)(H2,28,29,30,31);3-6,9-12H,1,7-8H2,2H3,(H,27,32)(H2,29,30,31).

What are the key properties of 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide?

4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide has a molecular weight of 2342.30 g/mol, XLogP of 27.44, 27 rotatable bonds, 14 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 4,5-difluoro-2-[[2-(2-methoxy-4-piperidin-1-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;4,5-difluoro-N-methyl-2-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]benzamide;N,N-dimethyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-2-carboxamide;N-methyl-3-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-4-carboxamide;N-methyl-4-[[2-[(2-methylidene-1,3-dihydroinden-5-yl)amino]-5-(trifluoromethyl)-4-pyridinyl]amino]pyridine-3-carboxamide is sourced from PubChem (CID 158257585), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).