N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol

C130H135N51OS4 — CID 158259218

About N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol

N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol (PubChem CID 158259218) has the molecular formula C130H135N51OS4 and a molecular weight of 2556.13 g/mol. Its IUPAC name is N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol.

Molecular Properties

• Compound Name: N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol
• PubChem CID: 158259218
• Molecular Formula: C130H135N51OS4
• Molecular Weight: 2556.13 g/mol
• Exact Mass: 2554.10
• IUPAC Name: N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol
• SMILES: CC(C)Cn1cc(-c2cnc3c(Nc4cccc(N(C)C)c4)nccn23)cn1.CN(C)c1cccc(Nc2nccn3c(-c4cnn(Cc5ccccc5)c4)cnc23)c1.CNCCc1cn2c(-c3cnn(C)c3)cnc2c(Nc2cc(C)ns2)n1.Cc1cc(Nc2nc(-c3cccnc3)cn3c(-c4cnn(C)c4)cnc23)sn1.Cc1cc(Nc2nc(CCCO)cn3c(-c4cnn(C)c4)cnc23)sn1.Cc1cc(Nc2nc(CCN)cn3c(-c4cnn(C)c4)cnc23)sn1.Nc1nccn2c(-c3cnn(Cc4ccccc4)c3)cnc12
• InChI: InChI=1S/C24H23N7.C21H25N7.C19H16N8S.C17H20N8S.C17H19N7OS.C16H18N8S.C16H14N6/c1-29(2)21-10-6-9-20(13-21)28-23-24-26-15-22(31(24)12-11-25-23)19-14-27-30(17-19)16-18-7-4-3-5-8-18;1-15(2)13-27-14-16(11-24-27)19-12-23-21-20(22-8-9-28(19)21)25-17-6-5-7-18(10-17)26(3)4;1-12-6-17(28-25-12)24-18-19-21-9-16(14-8-22-26(2)10-14)27(19)11-15(23-18)13-4-3-5-20-7-13;1-11-6-15(26-23-11)22-16-17-19-8-14(12-7-20-24(3)9-12)25(17)10-13(21-16)4-5-18-2;1-11-6-15(26-22-11)21-16-17-18-8-14(12-7-19-23(2)9-12)24(17)10-13(20-16)4-3-5-25;1-10-5-14(25-22-10)21-15-16-18-7-13(11-6-19-23(2)8-11)24(16)9-12(20-15)3-4-17;17-15-16-19-9-14(22(16)7-6-18-15)13-8-20-21(11-13)10-12-4-2-1-3-5-12/h3-15,17H,16H2,1-2H3,(H,25,28);5-12,14-15H,13H2,1-4H3,(H,22,25);3-11H,1-2H3,(H,23,24);6-10,18H,4-5H2,1-3H3,(H,21,22);6-10,25H,3-5H2,1-2H3,(H,20,21);5-9H,3-4,17H2,1-2H3,(H,20,21);1-9,11H,10H2,(H2,17,18)
• InChIKey: GHRALEDNMSIFLD-UHFFFAOYSA-N
• XLogP: 21.54
• TPSA: 563.48 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 56
• Rotatable Bonds: 36
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2556.13
LogP ≤ 5	21.54
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	56

Frequently Asked Questions

What is the IUPAC name of N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol?

The IUPAC name of N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol (CID 158259218) is N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol.

What is the SMILES notation for N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol?

The canonical SMILES for N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol is CC(C)Cn1cc(-c2cnc3c(Nc4cccc(N(C)C)c4)nccn23)cn1.CN(C)c1cccc(Nc2nccn3c(-c4cnn(Cc5ccccc5)c4)cnc23)c1.CNCCc1cn2c(-c3cnn(C)c3)cnc2c(Nc2cc(C)ns2)n1.Cc1cc(Nc2nc(-c3cccnc3)cn3c(-c4cnn(C)c4)cnc23)sn1.Cc1cc(Nc2nc(CCCO)cn3c(-c4cnn(C)c4)cnc23)sn1.Cc1cc(Nc2nc(CCN)cn3c(-c4cnn(C)c4)cnc23)sn1.Nc1nccn2c(-c3cnn(Cc4ccccc4)c3)cnc12.

What is the InChIKey of N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol?

The InChIKey is GHRALEDNMSIFLD-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H23N7.C21H25N7.C19H16N8S.C17H20N8S.C17H19N7OS.C16H18N8S.C16H14N6/c1-29(2)21-10-6-9-20(13-21)28-23-24-26-15-22(31(24)12-11-25-23)19-14-27-30(17-19)16-18-7-4-3-5-8-18;1-15(2)13-27-14-16(11-24-27)19-12-23-21-20(22-8-9-28(19)21)25-17-6-5-7-18(10-17)26(3)4;1-12-6-17(28-25-12)24-18-19-21-9-16(14-8-22-26(2)10-14)27(19)11-15(23-18)13-4-3-5-20-7-13;1-11-6-15(26-23-11)22-16-17-19-8-14(12-7-20-24(3)9-12)25(17)10-13(21-16)4-5-18-2;1-11-6-15(26-22-11)21-16-17-18-8-14(12-7-19-23(2)9-12)24(17)10-13(20-16)4-3-5-25;1-10-5-14(25-22-10)21-15-16-18-7-13(11-6-19-23(2)8-11)24(16)9-12(20-15)3-4-17;17-15-16-19-9-14(22(16)7-6-18-15)13-8-20-21(11-13)10-12-4-2-1-3-5-12/h3-15,17H,16H2,1-2H3,(H,25,28);5-12,14-15H,13H2,1-4H3,(H,22,25);3-11H,1-2H3,(H,23,24);6-10,18H,4-5H2,1-3H3,(H,21,22);6-10,25H,3-5H2,1-2H3,(H,20,21);5-9H,3-4,17H2,1-2H3,(H,20,21);1-9,11H,10H2,(H2,17,18).

What are the key properties of N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol?

N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol has a molecular weight of 2556.13 g/mol, XLogP of 21.54, 36 rotatable bonds, 10 hydrogen bond donors, and 56 hydrogen bond acceptors.

Where does this data come from?

All data for N-[6-(2-aminoethyl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-N-[3-(1-benzylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-[1-(2-methylpropyl)pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-methyl-N-[6-[2-(methylamino)ethyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-[3-(1-methylpyrazol-4-yl)-8-[(3-methyl-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-6-yl]propan-1-ol is sourced from PubChem (CID 158259218), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).