5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide

C94H76F9N17O13 — CID 158282706

IUPAC5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide
SMILESCOc1cnccc1NC(=O)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCCC2)o1.O=C(Nc1c(O)cncc1F)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCCC2(F)F)o1.O=C(Nc1cc[nH]c(=O)c1)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCOC2)o1.O=C(Nc1ccncn1)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2COCC2(F)F)o1
InChIInChI=1S/C25H23FN4O3.C24H18F4N4O3.C23H19FN4O4.C22H16F3N5O3/c1-32-22-14-27-13-12-19(22)29-25(31)21-11-10-20(33-21)24-23(16-6-8-17(26)9-7-16)28-15-30(24)18-4-2-3-5-18;25-14-5-3-13(4-6-14)20-22(32(12-30-20)19-2-1-9-24(19,27)28)17-7-8-18(35-17)23(34)31-21-15(26)10-29-11-16(21)33;24-15-3-1-14(2-4-15)21-22(28(13-26-21)17-8-10-31-12-17)18-5-6-19(32-18)23(30)27-16-7-9-25-20(29)11-16;23-14-3-1-13(2-4-14)19-20(30(12-28-19)17-9-32-10-22(17,24)25)15-5-6-16(33-15)21(31)29-18-7-8-26-11-27-18/h6-15,18H,2-5H2,1H3,(H,27,29,31);3-8,10-12,19,33H,1-2,9H2,(H,29,31,34);1-7,9,11,13,17H,8,10,12H2,(H2,25,27,29,30);1-8,11-12,17H,9-10H2,(H,26,27,29,31)
InChIKeyGKKDBZQLZPGVAY-UHFFFAOYSA-N
MW1822.73 g/mol
LogP19.57
Rot. Bonds21

About 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide

5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide (PubChem CID 158282706) has the molecular formula C94H76F9N17O13 and a molecular weight of 1822.73 g/mol. Its IUPAC name is 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide.

Molecular Properties

Compound Name5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide
PubChem CID158282706
Molecular FormulaC94H76F9N17O13
Molecular Weight1822.73 g/mol
Exact Mass1821.57
IUPAC Name5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide
SMILESCOc1cnccc1NC(=O)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCCC2)o1.O=C(Nc1c(O)cncc1F)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCCC2(F)F)o1.O=C(Nc1cc[nH]c(=O)c1)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCOC2)o1.O=C(Nc1ccncn1)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2COCC2(F)F)o1
InChIInChI=1S/C25H23FN4O3.C24H18F4N4O3.C23H19FN4O4.C22H16F3N5O3/c1-32-22-14-27-13-12-19(22)29-25(31)21-11-10-20(33-21)24-23(16-6-8-17(26)9-7-16)28-15-30(24)18-4-2-3-5-18;25-14-5-3-13(4-6-14)20-22(32(12-30-20)19-2-1-9-24(19,27)28)17-7-8-18(35-17)23(34)31-21-15(26)10-29-11-16(21)33;24-15-3-1-14(2-4-15)21-22(28(13-26-21)17-8-10-31-12-17)18-5-6-19(32-18)23(30)27-16-7-9-25-20(29)11-16;23-14-3-1-13(2-4-14)19-20(30(12-28-19)17-9-32-10-22(17,24)25)15-5-6-16(33-15)21(31)29-18-7-8-26-11-27-18/h6-15,18H,2-5H2,1H3,(H,27,29,31);3-8,10-12,19,33H,1-2,9H2,(H,29,31,34);1-7,9,11,13,17H,8,10,12H2,(H2,25,27,29,30);1-8,11-12,17H,9-10H2,(H,26,27,29,31)
InChIKeyGKKDBZQLZPGVAY-UHFFFAOYSA-N
XLogP19.57
TPSA372.58 Ų
H-Bond Donors6
H-Bond Acceptors25
Rotatable Bonds21
Heavy Atoms133
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001822.73
LogP ≤ 519.57
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1025

Analyze 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide with MolForge

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Related Compounds

5-(4-(4-fluorophenyl)-1-((tetrahydrofuran-3-yl)methyl)-1H-imidazol-5-yl)-N-(3-methoxypyridin-4-yl)furan-2-carboxamide
CID 154685917
N-(5-fluoro-2-methylpyridin-4-yl)-5-(4-(4-fluorophenyl)-1-(4-fluorotetrahydrofuran-3-yl)-1H-imidazol-5-yl)furan-2-carboxamide
CID 154685937
5-(4-(4-fluorophenyl)-1-(tetrahydrofuran-3-yl)-1H-imidazol-5-yl)-N-(3-methoxypyridin-4-yl)furan-2-carboxamide
CID 154685966
5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxypyridin-4-yl)furan-2-carboxamide
CID 154685988
Tnik&map4K4-IN-1
CID 155069016
5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide
CID 155069018
rac-5-(4-(4-fluorophenyl)-1-((1R,3S)-3-hydroxycyclopentyl)-1H-imidazol-5-yl)-N-(3-fluoropyridin-4-yl)furan-2-carboxamide
CID 155069019
N-(3-fluoro-5-hydroxy-4-pyridinyl)-5-[3-(4-fluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]furan-2-carboxamide
CID 154685940
N-(3-fluoro-5-hydroxypyridin-4-yl)-5-(4-(4-fluorophenyl)-1-(oxetan-3-yl)-1H-imidazol-5-yl)furan-2-carboxamide
CID 154685979
2-[cyclopentyl(methyl)amino]-N-[6-[4-[(2-fluorophenyl)carbamoyl]piperazin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)pyrimidine-5-carboxamide;2-(4-methoxyphenyl)-1-[4-[5-[2-oxo-2-[2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethyl]-2-pyridinyl]piperazin-1-yl]ethanone;2-[6-[4-[2-(2-methylphenyl)ethyl]piperazin-1-yl]-3-pyridinyl]-1-[2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethanone;1-[2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-[6-[4-[2-[2-(trifluoromethyl)phenyl]acetyl]piperazin-1-yl]-3-pyridinyl]ethanone;1-[2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-[6-[4-[2-(2,4,6-trimethylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]ethanone
CID 123736329
5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(5-fluoro-2-methylpyridin-4-yl)furan-2-carboxamide
CID 154685930
N-[3-fluoro-1-[3-[[4-(4-fluorophenyl)-5-[5-[(3-fluoro-4-pyridinyl)carbamoyl]furan-2-yl]imidazol-1-yl]methyl]-6-bicyclo[3.2.1]octanyl]pyridin-1-ium-4-yl]-5-[5-(4-fluorophenyl)-3-[(3-methylcycloheptyl)methyl]imidazol-4-yl]furan-2-carboxamide
CID 154686000

Frequently Asked Questions

What is the IUPAC name of 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide?
The IUPAC name of 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide (CID 158282706) is 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide.
What is the SMILES notation for 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide?
The canonical SMILES for 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide is COc1cnccc1NC(=O)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCCC2)o1.O=C(Nc1c(O)cncc1F)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCCC2(F)F)o1.O=C(Nc1cc[nH]c(=O)c1)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2CCOC2)o1.O=C(Nc1ccncn1)c1ccc(-c2c(-c3ccc(F)cc3)ncn2C2COCC2(F)F)o1.
What is the InChIKey of 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide?
The InChIKey is GKKDBZQLZPGVAY-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H23FN4O3.C24H18F4N4O3.C23H19FN4O4.C22H16F3N5O3/c1-32-22-14-27-13-12-19(22)29-25(31)21-11-10-20(33-21)24-23(16-6-8-17(26)9-7-16)28-15-30(24)18-4-2-3-5-18;25-14-5-3-13(4-6-14)20-22(32(12-30-20)19-2-1-9-24(19,27)28)17-7-8-18(35-17)23(34)31-21-15(26)10-29-11-16(21)33;24-15-3-1-14(2-4-15)21-22(28(13-26-21)17-8-10-31-12-17)18-5-6-19(32-18)23(30)27-16-7-9-25-20(29)11-16;23-14-3-1-13(2-4-14)19-20(30(12-28-19)17-9-32-10-22(17,24)25)15-5-6-16(33-15)21(31)29-18-7-8-26-11-27-18/h6-15,18H,2-5H2,1H3,(H,27,29,31);3-8,10-12,19,33H,1-2,9H2,(H,29,31,34);1-7,9,11,13,17H,8,10,12H2,(H2,25,27,29,30);1-8,11-12,17H,9-10H2,(H,26,27,29,31).
What are the key properties of 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide?
5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide has a molecular weight of 1822.73 g/mol, XLogP of 19.57, 21 rotatable bonds, 6 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[3-cyclopentyl-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-methoxy-4-pyridinyl)furan-2-carboxamide;5-[3-(2,2-difluorocyclopentyl)-5-(4-fluorophenyl)imidazol-4-yl]-N-(3-fluoro-5-hydroxy-4-pyridinyl)furan-2-carboxamide;5-[3-(4,4-difluorooxolan-3-yl)-5-(4-fluorophenyl)imidazol-4-yl]-N-pyrimidin-4-ylfuran-2-carboxamide;5-[5-(4-fluorophenyl)-3-(oxolan-3-yl)imidazol-4-yl]-N-(2-oxo-1H-pyridin-4-yl)furan-2-carboxamide is sourced from PubChem (CID 158282706), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).