3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

C239H291F24N49O13S — CID 158283197

IUPAC3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCCC1(c2cccc(F)c2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2CC1CC1.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2CC1CC1.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1ccc(N3CCC3)nc1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1ccc(S(C)(=O)=O)cn1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCC3)cc1F)C(=O)N2.CNC1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCOCC3)nc1C)C(=O)N2.Cc1cc(N2CCC2)cnc1N1CC2(CCC(c3cccc(F)c3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C25H31F4N5O.C25H29F4N5O.C25H30F4N4O.C25H32FN5O.C24H27F4N5O.2C24H30FN5O.C24H32N6O2.C22H27FN4O3S.C21H23F4N5O/c1-31(2)24(18-5-4-6-19(26)13-18)11-9-23(10-12-24)16-33(22(35)34(23)15-17-7-8-17)21-14-20(25(27,28)29)30-32(21)3;1-32(2)24(18-4-3-5-19(26)12-18)10-8-23(9-11-24)16-33(22(35)34(23)15-17-6-7-17)20-13-30-21(31-14-20)25(27,28)29;1-3-23(18-5-4-6-19(26)13-18)9-11-24(12-10-23)16-32(22(34)33(24)15-17-7-8-17)21-14-20(25(27,28)29)30-31(21)2;1-18-14-21(30-12-5-13-30)16-27-22(18)31-17-24(28-23(31)32)8-10-25(11-9-24,29(2)3)19-6-4-7-20(26)15-19;1-29-23(17-3-2-4-18(25)11-17)9-7-22(8-10-23)15-32(21(34)33(22)14-16-5-6-16)19-12-30-20(31-13-19)24(26,27)28;1-28(2)24(18-5-3-6-19(25)15-18)11-9-23(10-12-24)17-30(22(31)27-23)20-7-8-21(26-16-20)29-13-4-14-29;1-28(2)24(18-7-4-3-5-8-18)11-9-23(10-12-24)17-30(22(31)27-23)20-16-26-21(15-19(20)25)29-13-6-14-29;1-18-20(16-26-21(27-18)29-12-14-32-15-13-29)30-17-23(28-22(30)31)8-10-24(25-2,11-9-23)19-6-4-3-5-7-19;1-26(2)22(16-5-4-6-17(23)13-16)11-9-21(10-12-22)15-27(20(28)25-21)19-8-7-18(14-24-19)31(3,29)30;1-29(2)20(14-4-3-5-15(22)10-14)8-6-19(7-9-20)13-30(18(31)28-19)16-11-26-17(27-12-16)21(23,24)25/h4-6,13-14,17H,7-12,15-16H2,1-3H3;3-5,12-14,17H,6-11,15-16H2,1-2H3;4-6,13-14,17H,3,7-12,15-16H2,1-2H3;4,6-7,14-16H,5,8-13,17H2,1-3H3,(H,28,32);2-4,11-13,16,29H,5-10,14-15H2,1H3;3,5-8,15-16H,4,9-14,17H2,1-2H3,(H,27,31);3-5,7-8,15-16H,6,9-14,17H2,1-2H3,(H,27,31);3-7,16,25H,8-15,17H2,1-2H3,(H,28,31);4-8,13-14H,9-12,15H2,1-3H3,(H,25,28);3-5,10-12H,6-9,13H2,1-2H3,(H,28,31)
InChIKeyGKLLWVDFRWNQFV-UHFFFAOYSA-N
MW4546.31 g/mol
LogP41.60
Rot. Bonds43

About 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 158283197) has the molecular formula C239H291F24N49O13S and a molecular weight of 4546.31 g/mol. Its IUPAC name is 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Name3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
PubChem CID158283197
Molecular FormulaC239H291F24N49O13S
Molecular Weight4546.31 g/mol
Exact Mass4543.30
IUPAC Name3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCCC1(c2cccc(F)c2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2CC1CC1.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2CC1CC1.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1ccc(N3CCC3)nc1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1ccc(S(C)(=O)=O)cn1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCC3)cc1F)C(=O)N2.CNC1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCOCC3)nc1C)C(=O)N2.Cc1cc(N2CCC2)cnc1N1CC2(CCC(c3cccc(F)c3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C25H31F4N5O.C25H29F4N5O.C25H30F4N4O.C25H32FN5O.C24H27F4N5O.2C24H30FN5O.C24H32N6O2.C22H27FN4O3S.C21H23F4N5O/c1-31(2)24(18-5-4-6-19(26)13-18)11-9-23(10-12-24)16-33(22(35)34(23)15-17-7-8-17)21-14-20(25(27,28)29)30-32(21)3;1-32(2)24(18-4-3-5-19(26)12-18)10-8-23(9-11-24)16-33(22(35)34(23)15-17-6-7-17)20-13-30-21(31-14-20)25(27,28)29;1-3-23(18-5-4-6-19(26)13-18)9-11-24(12-10-23)16-32(22(34)33(24)15-17-7-8-17)21-14-20(25(27,28)29)30-31(21)2;1-18-14-21(30-12-5-13-30)16-27-22(18)31-17-24(28-23(31)32)8-10-25(11-9-24,29(2)3)19-6-4-7-20(26)15-19;1-29-23(17-3-2-4-18(25)11-17)9-7-22(8-10-23)15-32(21(34)33(22)14-16-5-6-16)19-12-30-20(31-13-19)24(26,27)28;1-28(2)24(18-5-3-6-19(25)15-18)11-9-23(10-12-24)17-30(22(31)27-23)20-7-8-21(26-16-20)29-13-4-14-29;1-28(2)24(18-7-4-3-5-8-18)11-9-23(10-12-24)17-30(22(31)27-23)20-16-26-21(15-19(20)25)29-13-6-14-29;1-18-20(16-26-21(27-18)29-12-14-32-15-13-29)30-17-23(28-22(30)31)8-10-24(25-2,11-9-23)19-6-4-3-5-7-19;1-26(2)22(16-5-4-6-17(23)13-16)11-9-21(10-12-22)15-27(20(28)25-21)19-8-7-18(14-24-19)31(3,29)30;1-29(2)20(14-4-3-5-15(22)10-14)8-6-19(7-9-20)13-30(18(31)28-19)16-11-26-17(27-12-16)21(23,24)25/h4-6,13-14,17H,7-12,15-16H2,1-3H3;3-5,12-14,17H,6-11,15-16H2,1-2H3;4-6,13-14,17H,3,7-12,15-16H2,1-2H3;4,6-7,14-16H,5,8-13,17H2,1-3H3,(H,28,32);2-4,11-13,16,29H,5-10,14-15H2,1H3;3,5-8,15-16H,4,9-14,17H2,1-2H3,(H,27,31);3-5,7-8,15-16H,6,9-14,17H2,1-2H3,(H,27,31);3-7,16,25H,8-15,17H2,1-2H3,(H,28,31);4-8,13-14H,9-12,15H2,1-3H3,(H,25,28);3-5,10-12H,6-9,13H2,1-2H3,(H,28,31)
InChIKeyGKLLWVDFRWNQFV-UHFFFAOYSA-N
XLogP41.60
TPSA581.63 Ų
H-Bond Donors8
H-Bond Acceptors42
Rotatable Bonds43
Heavy Atoms326
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004546.31
LogP ≤ 541.60
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1042

Analyze 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one with MolForge

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What is the IUPAC name of 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (CID 158283197) is 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is CCC1(c2cccc(F)c2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2CC1CC1.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2CC1CC1.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1ccc(N3CCC3)nc1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1ccc(S(C)(=O)=O)cn1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2.CN(C)C1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCC3)cc1F)C(=O)N2.CNC1(c2cccc(F)c2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(N3CCOCC3)nc1C)C(=O)N2.Cc1cc(N2CCC2)cnc1N1CC2(CCC(c3cccc(F)c3)(N(C)C)CC2)NC1=O.
What is the InChIKey of 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is GKLLWVDFRWNQFV-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H31F4N5O.C25H29F4N5O.C25H30F4N4O.C25H32FN5O.C24H27F4N5O.2C24H30FN5O.C24H32N6O2.C22H27FN4O3S.C21H23F4N5O/c1-31(2)24(18-5-4-6-19(26)13-18)11-9-23(10-12-24)16-33(22(35)34(23)15-17-7-8-17)21-14-20(25(27,28)29)30-32(21)3;1-32(2)24(18-4-3-5-19(26)12-18)10-8-23(9-11-24)16-33(22(35)34(23)15-17-6-7-17)20-13-30-21(31-14-20)25(27,28)29;1-3-23(18-5-4-6-19(26)13-18)9-11-24(12-10-23)16-32(22(34)33(24)15-17-7-8-17)21-14-20(25(27,28)29)30-31(21)2;1-18-14-21(30-12-5-13-30)16-27-22(18)31-17-24(28-23(31)32)8-10-25(11-9-24,29(2)3)19-6-4-7-20(26)15-19;1-29-23(17-3-2-4-18(25)11-17)9-7-22(8-10-23)15-32(21(34)33(22)14-16-5-6-16)19-12-30-20(31-13-19)24(26,27)28;1-28(2)24(18-5-3-6-19(25)15-18)11-9-23(10-12-24)17-30(22(31)27-23)20-7-8-21(26-16-20)29-13-4-14-29;1-28(2)24(18-7-4-3-5-8-18)11-9-23(10-12-24)17-30(22(31)27-23)20-16-26-21(15-19(20)25)29-13-6-14-29;1-18-20(16-26-21(27-18)29-12-14-32-15-13-29)30-17-23(28-22(30)31)8-10-24(25-2,11-9-23)19-6-4-3-5-7-19;1-26(2)22(16-5-4-6-17(23)13-16)11-9-21(10-12-22)15-27(20(28)25-21)19-8-7-18(14-24-19)31(3,29)30;1-29(2)20(14-4-3-5-15(22)10-14)8-6-19(7-9-20)13-30(18(31)28-19)16-11-26-17(27-12-16)21(23,24)25/h4-6,13-14,17H,7-12,15-16H2,1-3H3;3-5,12-14,17H,6-11,15-16H2,1-2H3;4-6,13-14,17H,3,7-12,15-16H2,1-2H3;4,6-7,14-16H,5,8-13,17H2,1-3H3,(H,28,32);2-4,11-13,16,29H,5-10,14-15H2,1H3;3,5-8,15-16H,4,9-14,17H2,1-2H3,(H,27,31);3-5,7-8,15-16H,6,9-14,17H2,1-2H3,(H,27,31);3-7,16,25H,8-15,17H2,1-2H3,(H,28,31);4-8,13-14H,9-12,15H2,1-3H3,(H,25,28);3-5,10-12H,6-9,13H2,1-2H3,(H,28,31).
What are the key properties of 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 4546.31 g/mol, XLogP of 41.60, 43 rotatable bonds, 8 hydrogen bond donors, and 42 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[6-(azetidin-1-yl)-4-fluoro-3-pyridinyl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[5-(azetidin-1-yl)-3-methyl-2-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;3-[6-(azetidin-1-yl)-3-pyridinyl]-8-(dimethylamino)-8-(3-fluorophenyl)-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-ethyl-8-(3-fluorophenyl)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(3-fluorophenyl)-8-(methylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-(5-methylsulfonyl-2-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-(3-fluorophenyl)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-3-(4-methyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 158283197), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).