N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide

C81H73FN18O10 — CID 158303781

IUPACN-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide
SMILESCCOC(=O)c1ccc2n[nH]c(/C=C/c3ccc(OC)c(F)c3)c2c1OC.COc1c(C(=O)NC2CC2)ccc2n[nH]c(/C=C/c3cnccn3)c12.COc1c(C(=O)NCc2ccccc2)ccc2n[nH]c(/C=C/c3cnccn3)c12.COc1c(C(=O)NCc2cccnc2)ccc2n[nH]c(/C=C/c3cnccn3)c12
InChIInChI=1S/C22H19N5O2.C21H18N6O2.C20H19FN2O4.C18H17N5O2/c1-29-21-17(22(28)25-13-15-5-3-2-4-6-15)8-10-19-20(21)18(26-27-19)9-7-16-14-23-11-12-24-16;1-29-20-16(21(28)25-12-14-3-2-8-22-11-14)5-7-18-19(20)17(26-27-18)6-4-15-13-23-9-10-24-15;1-4-27-20(24)13-7-9-16-18(19(13)26-3)15(22-23-16)8-5-12-6-10-17(25-2)14(21)11-12;1-25-17-13(18(24)21-11-2-3-11)5-7-15-16(17)14(22-23-15)6-4-12-10-19-8-9-20-12/h2-12,14H,13H2,1H3,(H,25,28)(H,26,27);2-11,13H,12H2,1H3,(H,25,28)(H,26,27);5-11H,4H2,1-3H3,(H,22,23);4-11H,2-3H2,1H3,(H,21,24)(H,22,23)/b9-7+;6-4+;8-5+;6-4+
InChIKeyGMVAKCBAFMQRFG-BKFKURHBSA-N
MW1477.59 g/mol
LogP12.81
Rot. Bonds23

About N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide

N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide (PubChem CID 158303781) has the molecular formula C81H73FN18O10 and a molecular weight of 1477.59 g/mol. Its IUPAC name is N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide.

Molecular Properties

Compound NameN-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide
PubChem CID158303781
Molecular FormulaC81H73FN18O10
Molecular Weight1477.59 g/mol
Exact Mass1476.57
IUPAC NameN-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide
SMILESCCOC(=O)c1ccc2n[nH]c(/C=C/c3ccc(OC)c(F)c3)c2c1OC.COc1c(C(=O)NC2CC2)ccc2n[nH]c(/C=C/c3cnccn3)c12.COc1c(C(=O)NCc2ccccc2)ccc2n[nH]c(/C=C/c3cnccn3)c12.COc1c(C(=O)NCc2cccnc2)ccc2n[nH]c(/C=C/c3cnccn3)c12
InChIInChI=1S/C22H19N5O2.C21H18N6O2.C20H19FN2O4.C18H17N5O2/c1-29-21-17(22(28)25-13-15-5-3-2-4-6-15)8-10-19-20(21)18(26-27-19)9-7-16-14-23-11-12-24-16;1-29-20-16(21(28)25-12-14-3-2-8-22-11-14)5-7-18-19(20)17(26-27-18)6-4-15-13-23-9-10-24-15;1-4-27-20(24)13-7-9-16-18(19(13)26-3)15(22-23-16)8-5-12-6-10-17(25-2)14(21)11-12;1-25-17-13(18(24)21-11-2-3-11)5-7-15-16(17)14(22-23-15)6-4-12-10-19-8-9-20-12/h2-12,14H,13H2,1H3,(H,25,28)(H,26,27);2-11,13H,12H2,1H3,(H,25,28)(H,26,27);5-11H,4H2,1-3H3,(H,22,23);4-11H,2-3H2,1H3,(H,21,24)(H,22,23)/b9-7+;6-4+;8-5+;6-4+
InChIKeyGMVAKCBAFMQRFG-BKFKURHBSA-N
XLogP12.81
TPSA364.70 Ų
H-Bond Donors7
H-Bond Acceptors21
Rotatable Bonds23
Heavy Atoms110
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001477.59
LogP ≤ 512.81
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1021

Analyze N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide with MolForge

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Related Compounds

3-[(E)-2-(3,4-difluorophenyl)ethenyl]-4-methoxy-N-(pyrazin-2-ylmethyl)-1H-indazole-5-carboxamide
CID 60034617
3-[(E)-2-(2,4-difluorophenyl)ethenyl]-4-methoxy-N-(pyrazin-2-ylmethyl)-1H-indazole-5-carboxamide
CID 60035116
3-[(E)-2-(3-acetyl-4-fluorophenyl)ethenyl]-4-methoxy-N-(pyrazin-2-ylmethyl)-1H-indazole-5-carboxamide
CID 60053849
N-[(3R,6S)-1-[(2-fluoro-6-methoxyphenyl)methyl]-6-[(6-methyl-3-pyridinyl)carbamoyl]piperidin-3-yl]-3-(2-methyl-4-pyridinyl)-1H-indazole-5-carboxamide
CID 70652247
methyl 4-[(2S,5R)-1-[(2-fluoro-6-methoxyphenyl)methyl]-5-[[3-(2-methyl-4-pyridinyl)-1H-indazole-5-carbonyl]amino]piperidine-2-carbonyl]piperazine-1-carboxylate
CID 70652345
(1-methylcyclopropyl) 4-[(2S,5R)-1-[(2-fluoro-6-methoxyphenyl)methyl]-5-[[3-(2-methyl-4-pyridinyl)-1H-indazole-5-carbonyl]amino]piperidine-2-carbonyl]piperazine-1-carboxylate
CID 70652588
ethyl 4-[(2S,5R)-1-[(2-fluoro-6-methoxyphenyl)methyl]-5-[[3-(2-methyl-4-pyridinyl)-1H-indazole-5-carbonyl]amino]piperidine-2-carbonyl]piperazine-1-carboxylate
CID 70653112
oxan-4-yl 4-[(2S,5R)-1-[(2-fluoro-6-methoxyphenyl)methyl]-5-[[3-(2-methyl-4-pyridinyl)-1H-indazole-5-carbonyl]amino]piperidine-2-carbonyl]piperazine-1-carboxylate
CID 89499211
N-[(3R,6S)-1-[(2-fluoro-6-methoxyphenyl)methyl]-6-(pyridin-3-ylcarbamoyl)piperidin-3-yl]-3-(2-methyl-4-pyridinyl)-1H-indazole-5-carboxamide
CID 89499257
3-[2-(3,4-difluorophenyl)ethenyl]-4-methoxy-N-(pyrazin-2-ylmethyl)-1H-indazole-5-carboxamide
CID 90689014
3-[2-(2,4-difluorophenyl)ethenyl]-4-methoxy-N-(pyrazin-2-ylmethyl)-1H-indazole-5-carboxamide
CID 90743686
3-[2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-N-(pyridin-2-ylmethyl)-1H-indazole-5-carboxamide
CID 90839309

Frequently Asked Questions

What is the IUPAC name of N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide?
The IUPAC name of N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide (CID 158303781) is N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide.
What is the SMILES notation for N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide?
The canonical SMILES for N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide is CCOC(=O)c1ccc2n[nH]c(/C=C/c3ccc(OC)c(F)c3)c2c1OC.COc1c(C(=O)NC2CC2)ccc2n[nH]c(/C=C/c3cnccn3)c12.COc1c(C(=O)NCc2ccccc2)ccc2n[nH]c(/C=C/c3cnccn3)c12.COc1c(C(=O)NCc2cccnc2)ccc2n[nH]c(/C=C/c3cnccn3)c12.
What is the InChIKey of N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide?
The InChIKey is GMVAKCBAFMQRFG-BKFKURHBSA-N. The full InChI is InChI=1S/C22H19N5O2.C21H18N6O2.C20H19FN2O4.C18H17N5O2/c1-29-21-17(22(28)25-13-15-5-3-2-4-6-15)8-10-19-20(21)18(26-27-19)9-7-16-14-23-11-12-24-16;1-29-20-16(21(28)25-12-14-3-2-8-22-11-14)5-7-18-19(20)17(26-27-18)6-4-15-13-23-9-10-24-15;1-4-27-20(24)13-7-9-16-18(19(13)26-3)15(22-23-16)8-5-12-6-10-17(25-2)14(21)11-12;1-25-17-13(18(24)21-11-2-3-11)5-7-15-16(17)14(22-23-15)6-4-12-10-19-8-9-20-12/h2-12,14H,13H2,1H3,(H,25,28)(H,26,27);2-11,13H,12H2,1H3,(H,25,28)(H,26,27);5-11H,4H2,1-3H3,(H,22,23);4-11H,2-3H2,1H3,(H,21,24)(H,22,23)/b9-7+;6-4+;8-5+;6-4+.
What are the key properties of N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide?
N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide has a molecular weight of 1477.59 g/mol, XLogP of 12.81, 23 rotatable bonds, 7 hydrogen bond donors, and 21 hydrogen bond acceptors.
Where does this data come from?
All data for N-benzyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-2H-indazole-5-carboxamide;ethyl 3-[(E)-2-(3-fluoro-4-methoxyphenyl)ethenyl]-4-methoxy-2H-indazole-5-carboxylate;4-methoxy-3-[(E)-2-pyrazin-2-ylethenyl]-N-(pyridin-3-ylmethyl)-2H-indazole-5-carboxamide is sourced from PubChem (CID 158303781), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).