2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide

C147H171N21O10 — CID 158318168

About 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide

2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide (PubChem CID 158318168) has the molecular formula C147H171N21O10 and a molecular weight of 2392.12 g/mol. Its IUPAC name is 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide.

Molecular Properties

• Compound Name: 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide
• PubChem CID: 158318168
• Molecular Formula: C147H171N21O10
• Molecular Weight: 2392.12 g/mol
• Exact Mass: 2390.35
• IUPAC Name: 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide
• SMILES: CC(=O)C1(c2ccccc2)CCN(CC(=O)NC2CCc3ccccc3C2Cc2cccnc2)CC1.COc1ccccc1N1CCN(CC(=O)NCC(Cc2cccnc2)c2ccccc2)CC1.COc1ccccc1N1CCN(CCNC2CCc3ccccc3C2Cc2cccnc2)CC1.O=C(CN1CCC2(CC1)C(=O)NCN2c1ccccc1)NC1CCc2cc(O)ccc2C1Cc1cccnc1.O=C(CN1CCC2(CC1)C(=O)NCN2c1ccccc1)NCC(Cc1cccnc1)c1ccccc1
• InChI: InChI=1S/C31H35N5O3.C31H35N3O2.C29H33N5O2.C29H36N4O.C27H32N4O2/c37-25-9-10-26-23(18-25)8-11-28(27(26)17-22-5-4-14-32-19-22)34-29(38)20-35-15-12-31(13-16-35)30(39)33-21-36(31)24-6-2-1-3-7-24;1-23(35)31(26-10-3-2-4-11-26)15-18-34(19-16-31)22-30(36)33-29-14-13-25-9-5-6-12-27(25)28(29)20-24-8-7-17-32-21-24;35-27(31-20-25(24-9-3-1-4-10-24)18-23-8-7-15-30-19-23)21-33-16-13-29(14-17-33)28(36)32-22-34(29)26-11-5-2-6-12-26;1-34-29-11-5-4-10-28(29)33-19-17-32(18-20-33)16-15-31-27-13-12-24-8-2-3-9-25(24)26(27)21-23-7-6-14-30-22-23;1-33-26-12-6-5-11-25(26)31-16-14-30(15-17-31)21-27(32)29-20-24(23-9-3-2-4-10-23)18-22-8-7-13-28-19-22/h1-7,9-10,14,18-19,27-28,37H,8,11-13,15-17,20-21H2,(H,33,39)(H,34,38);2-12,17,21,28-29H,13-16,18-20,22H2,1H3,(H,33,36);1-12,15,19,25H,13-14,16-18,20-22H2,(H,31,35)(H,32,36);2-11,14,22,26-27,31H,12-13,15-21H2,1H3;2-13,19,24H,14-18,20-21H2,1H3,(H,29,32)
• InChIKey: GONDTNJFADYOLX-UHFFFAOYSA-N
• XLogP: 17.89
• TPSA: 336.00 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 25
• Rotatable Bonds: 38
• Heavy Atoms: 178
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2392.12
LogP ≤ 5	17.89
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide?

The IUPAC name of 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide (CID 158318168) is 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide.

What is the SMILES notation for 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide?

The canonical SMILES for 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide is CC(=O)C1(c2ccccc2)CCN(CC(=O)NC2CCc3ccccc3C2Cc2cccnc2)CC1.COc1ccccc1N1CCN(CC(=O)NCC(Cc2cccnc2)c2ccccc2)CC1.COc1ccccc1N1CCN(CCNC2CCc3ccccc3C2Cc2cccnc2)CC1.O=C(CN1CCC2(CC1)C(=O)NCN2c1ccccc1)NC1CCc2cc(O)ccc2C1Cc1cccnc1.O=C(CN1CCC2(CC1)C(=O)NCN2c1ccccc1)NCC(Cc1cccnc1)c1ccccc1.

What is the InChIKey of 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide?

The InChIKey is GONDTNJFADYOLX-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H35N5O3.C31H35N3O2.C29H33N5O2.C29H36N4O.C27H32N4O2/c37-25-9-10-26-23(18-25)8-11-28(27(26)17-22-5-4-14-32-19-22)34-29(38)20-35-15-12-31(13-16-35)30(39)33-21-36(31)24-6-2-1-3-7-24;1-23(35)31(26-10-3-2-4-11-26)15-18-34(19-16-31)22-30(36)33-29-14-13-25-9-5-6-12-27(25)28(29)20-24-8-7-17-32-21-24;35-27(31-20-25(24-9-3-1-4-10-24)18-23-8-7-15-30-19-23)21-33-16-13-29(14-17-33)28(36)32-22-34(29)26-11-5-2-6-12-26;1-34-29-11-5-4-10-28(29)33-19-17-32(18-20-33)16-15-31-27-13-12-24-8-2-3-9-25(24)26(27)21-23-7-6-14-30-22-23;1-33-26-12-6-5-11-25(26)31-16-14-30(15-17-31)21-27(32)29-20-24(23-9-3-2-4-10-23)18-22-8-7-13-28-19-22/h1-7,9-10,14,18-19,27-28,37H,8,11-13,15-17,20-21H2,(H,33,39)(H,34,38);2-12,17,21,28-29H,13-16,18-20,22H2,1H3,(H,33,36);1-12,15,19,25H,13-14,16-18,20-22H2,(H,31,35)(H,32,36);2-11,14,22,26-27,31H,12-13,15-21H2,1H3;2-13,19,24H,14-18,20-21H2,1H3,(H,29,32).

What are the key properties of 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide?

2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide has a molecular weight of 2392.12 g/mol, XLogP of 17.89, 38 rotatable bonds, 8 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(4-acetyl-4-phenylpiperidin-1-yl)-N-[1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide;N-[6-hydroxy-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)acetamide;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide;2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-N-(2-phenyl-3-pyridin-3-ylpropyl)acetamide is sourced from PubChem (CID 158318168), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).