N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide

C208H169Cl14F18N55O21S6 — CID 158322278

IUPACN-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide
SMILESCC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2cc(C(C)(C)C)c(Cl)nn2)s1.CC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ccc(C(F)(F)F)c(Cl)c2)s1.CC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ncc(Cl)c(C(C)(C)C)n2)s1.C[C@@H](CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)s1.C[C@@H](CC(=O)c1ncnc(C#CCCCO)c1Cl)c1cc(C2=Nc3cnc(C(C)(C)C)nc3C2)no1.C[C@H](CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.C[C@H](CC(=O)c1ncnc(C#CCCCO)c1Cl)c1cc(C2=Nc3ccc(C(F)(F)F)cc3C2)on1.Cc1ccc(NC(=O)c2cnc(CCC(=O)c3ncnc(-c4ncc[nH]4)c3Cl)s2)cc1C(F)(F)F.O=C(CCc1cc(C2=Nc3ccc(C(F)(F)F)cc3C2)on1)c1ncnc(C#CCCCO)c1Cl
InChIInChI=1S/C26H27ClN6O3.C25H20ClF3N4O3.C24H18ClF3N4O3.2C23H22Cl2N8O2S.2C22H15Cl2F3N6O2S.C22H16ClF3N6O2S.C21H14Cl2F3N7O2S/c1-15(10-21(35)24-23(27)16(29-14-30-24)8-6-5-7-9-34)22-12-19(33-36-22)17-11-18-20(31-17)13-28-25(32-18)26(2,3)4;1-14(9-21(35)24-23(26)18(30-13-31-24)5-3-2-4-8-34)19-12-22(36-33-19)20-11-15-10-16(25(27,28)29)6-7-17(15)32-20;25-22-18(4-2-1-3-9-33)29-13-30-23(22)20(34)8-6-16-12-21(35-32-16)19-11-14-10-15(24(26,27)28)5-7-17(14)31-19;1-11(7-13(34)16-15(25)17(31-10-30-16)19-26-5-6-27-19)21-28-9-14(36-21)20(35)33-22-29-8-12(24)18(32-22)23(2,3)4;1-11(7-13(34)17-16(24)18(30-10-29-17)20-26-5-6-27-20)22-28-9-14(36-22)21(35)31-15-8-12(23(2,3)4)19(25)33-32-15;1-10(6-14(34)17-16(24)18(32-9-31-17)19-28-4-5-29-19)21-30-8-15(36-21)20(35)33-11-2-3-13(23)12(7-11)22(25,26)27;1-10(6-14(34)17-16(24)18(32-9-31-17)19-28-4-5-29-19)21-30-8-15(36-21)20(35)33-11-2-3-12(13(23)7-11)22(25,26)27;1-11-2-3-12(8-13(11)22(24,25)26)32-21(34)15-9-29-16(35-15)5-4-14(33)18-17(23)19(31-10-30-18)20-27-6-7-28-20;1-9(4-12(34)16-15(23)17(32-8-31-16)18-27-2-3-28-18)20-30-7-13(36-20)19(35)33-14-5-10(21(24,25)26)11(22)6-29-14/h12-15,34H,5,7,9-11H2,1-4H3;6-7,10,12-14,34H,2,4,8-9,11H2,1H3;5,7,10,12-13,33H,1,3,6,8-9,11H2;5-6,8-11H,7H2,1-4H3,(H,26,27)(H,29,32,33,35);5-6,8-11H,7H2,1-4H3,(H,26,27)(H,31,32,35);2*2-5,7-10H,6H2,1H3,(H,28,29)(H,33,35);2-3,6-10H,4-5H2,1H3,(H,27,28)(H,32,34);2-3,5-9H,4H2,1H3,(H,27,28)(H,29,33,35)/t15-;14-;;;;10-;;;9-/m01...0..1/s1
InChIKeyGOZNGPIDQOPVMV-LTDPUNFTSA-N
MW4805.71 g/mol
LogP48.74
Rot. Bonds63

About N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide

N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide (PubChem CID 158322278) has the molecular formula C208H169Cl14F18N55O21S6 and a molecular weight of 4805.71 g/mol. Its IUPAC name is N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide.

Molecular Properties

Compound NameN-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide
PubChem CID158322278
Molecular FormulaC208H169Cl14F18N55O21S6
Molecular Weight4805.71 g/mol
Exact Mass4795.75
IUPAC NameN-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide
SMILESCC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2cc(C(C)(C)C)c(Cl)nn2)s1.CC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ccc(C(F)(F)F)c(Cl)c2)s1.CC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ncc(Cl)c(C(C)(C)C)n2)s1.C[C@@H](CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)s1.C[C@@H](CC(=O)c1ncnc(C#CCCCO)c1Cl)c1cc(C2=Nc3cnc(C(C)(C)C)nc3C2)no1.C[C@H](CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.C[C@H](CC(=O)c1ncnc(C#CCCCO)c1Cl)c1cc(C2=Nc3ccc(C(F)(F)F)cc3C2)on1.Cc1ccc(NC(=O)c2cnc(CCC(=O)c3ncnc(-c4ncc[nH]4)c3Cl)s2)cc1C(F)(F)F.O=C(CCc1cc(C2=Nc3ccc(C(F)(F)F)cc3C2)on1)c1ncnc(C#CCCCO)c1Cl
InChIInChI=1S/C26H27ClN6O3.C25H20ClF3N4O3.C24H18ClF3N4O3.2C23H22Cl2N8O2S.2C22H15Cl2F3N6O2S.C22H16ClF3N6O2S.C21H14Cl2F3N7O2S/c1-15(10-21(35)24-23(27)16(29-14-30-24)8-6-5-7-9-34)22-12-19(33-36-22)17-11-18-20(31-17)13-28-25(32-18)26(2,3)4;1-14(9-21(35)24-23(26)18(30-13-31-24)5-3-2-4-8-34)19-12-22(36-33-19)20-11-15-10-16(25(27,28)29)6-7-17(15)32-20;25-22-18(4-2-1-3-9-33)29-13-30-23(22)20(34)8-6-16-12-21(35-32-16)19-11-14-10-15(24(26,27)28)5-7-17(14)31-19;1-11(7-13(34)16-15(25)17(31-10-30-16)19-26-5-6-27-19)21-28-9-14(36-21)20(35)33-22-29-8-12(24)18(32-22)23(2,3)4;1-11(7-13(34)17-16(24)18(30-10-29-17)20-26-5-6-27-20)22-28-9-14(36-22)21(35)31-15-8-12(23(2,3)4)19(25)33-32-15;1-10(6-14(34)17-16(24)18(32-9-31-17)19-28-4-5-29-19)21-30-8-15(36-21)20(35)33-11-2-3-13(23)12(7-11)22(25,26)27;1-10(6-14(34)17-16(24)18(32-9-31-17)19-28-4-5-29-19)21-30-8-15(36-21)20(35)33-11-2-3-12(13(23)7-11)22(25,26)27;1-11-2-3-12(8-13(11)22(24,25)26)32-21(34)15-9-29-16(35-15)5-4-14(33)18-17(23)19(31-10-30-18)20-27-6-7-28-20;1-9(4-12(34)16-15(23)17(32-8-31-16)18-27-2-3-28-18)20-30-7-13(36-20)19(35)33-14-5-10(21(24,25)26)11(22)6-29-14/h12-15,34H,5,7,9-11H2,1-4H3;6-7,10,12-14,34H,2,4,8-9,11H2,1H3;5,7,10,12-13,33H,1,3,6,8-9,11H2;5-6,8-11H,7H2,1-4H3,(H,26,27)(H,29,32,33,35);5-6,8-11H,7H2,1-4H3,(H,26,27)(H,31,32,35);2*2-5,7-10H,6H2,1H3,(H,28,29)(H,33,35);2-3,6-10H,4-5H2,1H3,(H,27,28)(H,32,34);2-3,5-9H,4H2,1H3,(H,27,28)(H,29,33,35)/t15-;14-;;;;10-;;;9-/m01...0..1/s1
InChIKeyGOZNGPIDQOPVMV-LTDPUNFTSA-N
XLogP48.74
TPSA1075.76 Ų
H-Bond Donors15
H-Bond Acceptors70
Rotatable Bonds63
Heavy Atoms322
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004805.71
LogP ≤ 548.74
H-Bond Donors ≤ 515
H-Bond Acceptors ≤ 1070

Analyze N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide?
The IUPAC name of N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide (CID 158322278) is N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide.
What is the SMILES notation for N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide?
The canonical SMILES for N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide is CC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2cc(C(C)(C)C)c(Cl)nn2)s1.CC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ccc(C(F)(F)F)c(Cl)c2)s1.CC(CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ncc(Cl)c(C(C)(C)C)n2)s1.C[C@@H](CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)s1.C[C@@H](CC(=O)c1ncnc(C#CCCCO)c1Cl)c1cc(C2=Nc3cnc(C(C)(C)C)nc3C2)no1.C[C@H](CC(=O)c1ncnc(-c2ncc[nH]2)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.C[C@H](CC(=O)c1ncnc(C#CCCCO)c1Cl)c1cc(C2=Nc3ccc(C(F)(F)F)cc3C2)on1.Cc1ccc(NC(=O)c2cnc(CCC(=O)c3ncnc(-c4ncc[nH]4)c3Cl)s2)cc1C(F)(F)F.O=C(CCc1cc(C2=Nc3ccc(C(F)(F)F)cc3C2)on1)c1ncnc(C#CCCCO)c1Cl.
What is the InChIKey of N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide?
The InChIKey is GOZNGPIDQOPVMV-LTDPUNFTSA-N. The full InChI is InChI=1S/C26H27ClN6O3.C25H20ClF3N4O3.C24H18ClF3N4O3.2C23H22Cl2N8O2S.2C22H15Cl2F3N6O2S.C22H16ClF3N6O2S.C21H14Cl2F3N7O2S/c1-15(10-21(35)24-23(27)16(29-14-30-24)8-6-5-7-9-34)22-12-19(33-36-22)17-11-18-20(31-17)13-28-25(32-18)26(2,3)4;1-14(9-21(35)24-23(26)18(30-13-31-24)5-3-2-4-8-34)19-12-22(36-33-19)20-11-15-10-16(25(27,28)29)6-7-17(15)32-20;25-22-18(4-2-1-3-9-33)29-13-30-23(22)20(34)8-6-16-12-21(35-32-16)19-11-14-10-15(24(26,27)28)5-7-17(14)31-19;1-11(7-13(34)16-15(25)17(31-10-30-16)19-26-5-6-27-19)21-28-9-14(36-21)20(35)33-22-29-8-12(24)18(32-22)23(2,3)4;1-11(7-13(34)17-16(24)18(30-10-29-17)20-26-5-6-27-20)22-28-9-14(36-22)21(35)31-15-8-12(23(2,3)4)19(25)33-32-15;1-10(6-14(34)17-16(24)18(32-9-31-17)19-28-4-5-29-19)21-30-8-15(36-21)20(35)33-11-2-3-13(23)12(7-11)22(25,26)27;1-10(6-14(34)17-16(24)18(32-9-31-17)19-28-4-5-29-19)21-30-8-15(36-21)20(35)33-11-2-3-12(13(23)7-11)22(25,26)27;1-11-2-3-12(8-13(11)22(24,25)26)32-21(34)15-9-29-16(35-15)5-4-14(33)18-17(23)19(31-10-30-18)20-27-6-7-28-20;1-9(4-12(34)16-15(23)17(32-8-31-16)18-27-2-3-28-18)20-30-7-13(36-20)19(35)33-14-5-10(21(24,25)26)11(22)6-29-14/h12-15,34H,5,7,9-11H2,1-4H3;6-7,10,12-14,34H,2,4,8-9,11H2,1H3;5,7,10,12-13,33H,1,3,6,8-9,11H2;5-6,8-11H,7H2,1-4H3,(H,26,27)(H,29,32,33,35);5-6,8-11H,7H2,1-4H3,(H,26,27)(H,31,32,35);2*2-5,7-10H,6H2,1H3,(H,28,29)(H,33,35);2-3,6-10H,4-5H2,1H3,(H,27,28)(H,32,34);2-3,5-9H,4H2,1H3,(H,27,28)(H,29,33,35)/t15-;14-;;;;10-;;;9-/m01...0..1/s1.
What are the key properties of N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide?
N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide has a molecular weight of 4805.71 g/mol, XLogP of 48.74, 63 rotatable bonds, 15 hydrogen bond donors, and 70 hydrogen bond acceptors.
Where does this data come from?
All data for N-(5-tert-butyl-6-chloropyridazin-3-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-(4-tert-butyl-5-chloropyrimidin-2-yl)-2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;(3S)-3-[3-(2-tert-butyl-7H-pyrrolo[3,2-d]pyrimidin-6-yl)-1,2-oxazol-5-yl]-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]butan-1-one;(3R)-1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]butan-1-one;1-[5-chloro-6-(5-hydroxypent-1-ynyl)pyrimidin-4-yl]-3-[5-[5-(trifluoromethyl)-3H-indol-2-yl]-1,2-oxazol-3-yl]propan-1-one;2-[(2S)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;2-[(2R)-4-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[3-[5-chloro-6-(1H-imidazol-2-yl)pyrimidin-4-yl]-3-oxopropyl]-N-[4-methyl-3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide is sourced from PubChem (CID 158322278), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).