8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine

C72H70F3N17O4 — CID 158335792

About 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine

8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine (PubChem CID 158335792) has the molecular formula C72H70F3N17O4 and a molecular weight of 1294.46 g/mol. Its IUPAC name is 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

• Compound Name: 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine
• PubChem CID: 158335792
• Molecular Formula: C72H70F3N17O4
• Molecular Weight: 1294.46 g/mol
• Exact Mass: 1293.57
• IUPAC Name: 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine
• SMILES: Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C(=O)N4CCN(C)CC4)cc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C4CC4)nc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccnn3C)c2n1
• InChI: InChI=1S/C28H29FN6O2.C24H22FN5O.C20H19FN6O/c1-18-17-35-26(32-18)22(19-3-5-20(6-4-19)27(36)34-12-10-33(2)11-13-34)15-30-28(35)31-16-23-21-9-14-37-25(21)8-7-24(23)29;1-14-13-30-23(29-14)18(16-4-6-21(26-10-16)15-2-3-15)11-27-24(30)28-12-19-17-8-9-31-22(17)7-5-20(19)25;1-12-11-27-19(25-12)15(17-5-7-24-26(17)2)10-23-20(27)22-9-14-13-6-8-28-18(13)4-3-16(14)21/h3-8,15,17H,9-14,16H2,1-2H3,(H,30,31);4-7,10-11,13,15H,2-3,8-9,12H2,1H3,(H,27,28);3-5,7,10-11H,6,8-9H2,1-2H3,(H,22,23)
• InChIKey: GQOGEMPPQTVSPN-UHFFFAOYSA-N
• XLogP: 11.57
• TPSA: 208.61 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 20
• Rotatable Bonds: 14
• Heavy Atoms: 96
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1294.46
LogP ≤ 5	11.57
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine?

The IUPAC name of 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine (CID 158335792) is 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine.

What is the SMILES notation for 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine?

The canonical SMILES for 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine is Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C(=O)N4CCN(C)CC4)cc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C4CC4)nc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccnn3C)c2n1.

What is the InChIKey of 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine?

The InChIKey is GQOGEMPPQTVSPN-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H29FN6O2.C24H22FN5O.C20H19FN6O/c1-18-17-35-26(32-18)22(19-3-5-20(6-4-19)27(36)34-12-10-33(2)11-13-34)15-30-28(35)31-16-23-21-9-14-37-25(21)8-7-24(23)29;1-14-13-30-23(29-14)18(16-4-6-21(26-10-16)15-2-3-15)11-27-24(30)28-12-19-17-8-9-31-22(17)7-5-20(19)25;1-12-11-27-19(25-12)15(17-5-7-24-26(17)2)10-23-20(27)22-9-14-13-6-8-28-18(13)4-3-16(14)21/h3-8,15,17H,9-14,16H2,1-2H3,(H,30,31);4-7,10-11,13,15H,2-3,8-9,12H2,1H3,(H,27,28);3-5,7,10-11H,6,8-9H2,1-2H3,(H,22,23).

What are the key properties of 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine?

8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 1294.46 g/mol, XLogP of 11.57, 14 rotatable bonds, 3 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(6-cyclopropyl-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 158335792), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).