3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide

C264H277Cl5N52O16 — CID 158341991

IUPAC3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide
SMILESCOc1cccc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)c1O.Cc1cc(C)cc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)c1.Cc1cc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)ccc1O.Cc1ccc(CCc2n[nH]c(Cc3ccc(-n4cccc4)cc3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3ccc(Cc4ccccc4)cc3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3ccc4[nH]ncc4c3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)cn1.Cc1ccc(CNc2n[nH]c(Cc3ccc(-c4ccn[nH]4)cc3)c2C(N)=O)cc1.Cc1ccc(CNc2n[nH]c(Cc3ccc(N4CCN(C(C)C)CC4)cc3)c2C(N)=O)cc1.Cc1ncc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)cn1.NC(=O)c1c(CCc2ccc(N)cc2)n[nH]c1Cc1ccc(N2CCCCC2)cc1.NC(=O)c1c(CCc2ccc(O)cc2)n[nH]c1Cc1ccc(-n2cccn2)cc1
InChIInChI=1S/C27H27N3O.C26H34N6O.C24H29N5O.C24H24N4O.C22H22N6O.C22H21N5O2.C21H22ClN3O.C21H21N5O.C20H20ClN3O3.C20H20ClN3O2.C19H19ClN4O.C18H18ClN5O/c1-19-7-9-20(10-8-19)15-16-24-26(27(28)31)25(30-29-24)18-23-13-11-22(12-14-23)17-21-5-3-2-4-6-21;1-18(2)31-12-14-32(15-13-31)22-10-8-20(9-11-22)16-23-24(25(27)33)26(30-29-23)28-17-21-6-4-19(3)5-7-21;25-19-9-4-17(5-10-19)8-13-21-23(24(26)30)22(28-27-21)16-18-6-11-20(12-7-18)29-14-2-1-3-15-29;1-17-4-6-18(7-5-17)10-13-21-23(24(25)29)22(27-26-21)16-19-8-11-20(12-9-19)28-14-2-3-15-28;1-14-2-4-16(5-3-14)13-24-22-20(21(23)29)19(27-28-22)12-15-6-8-17(9-7-15)18-10-11-25-26-18;23-22(29)21-19(11-6-15-4-9-18(28)10-5-15)25-26-20(21)14-16-2-7-17(8-3-16)27-13-1-12-24-27;1-13-8-14(2)10-16(9-13)6-7-18-20(21(23)26)19(25-24-18)12-15-4-3-5-17(22)11-15;1-13-2-4-14(5-3-13)6-9-18-20(21(22)27)19(26-25-18)11-15-7-8-17-16(10-15)12-23-24-17;1-27-17-7-3-5-13(19(17)25)8-9-15-18(20(22)26)16(24-23-15)11-12-4-2-6-14(21)10-12;1-12-9-13(6-8-18(12)25)5-7-16-19(20(22)26)17(24-23-16)11-14-3-2-4-15(21)10-14;1-12-5-6-13(11-22-12)7-8-16-18(19(21)25)17(24-23-16)10-14-3-2-4-15(20)9-14;1-11-21-9-13(10-22-11)5-6-15-17(18(20)25)16(24-23-15)8-12-3-2-4-14(19)7-12/h2-14H,15-18H2,1H3,(H2,28,31)(H,29,30);4-11,18H,12-17H2,1-3H3,(H2,27,33)(H2,28,29,30);4-7,9-12H,1-3,8,13-16,25H2,(H2,26,30)(H,27,28);2-9,11-12,14-15H,10,13,16H2,1H3,(H2,25,29)(H,26,27);2-11H,12-13H2,1H3,(H2,23,29)(H,25,26)(H2,24,27,28);1-5,7-10,12-13,28H,6,11,14H2,(H2,23,29)(H,25,26);3-5,8-11H,6-7,12H2,1-2H3,(H2,23,26)(H,24,25);2-5,7-8,10,12H,6,9,11H2,1H3,(H2,22,27)(H,23,24)(H,25,26);2-7,10,25H,8-9,11H2,1H3,(H2,22,26)(H,23,24);2-4,6,8-10,25H,5,7,11H2,1H3,(H2,22,26)(H,23,24);2-6,9,11H,7-8,10H2,1H3,(H2,21,25)(H,23,24);2-4,7,9-10H,5-6,8H2,1H3,(H2,20,25)(H,23,24)
InChIKeyGRGURRLLBJHZRZ-UHFFFAOYSA-N
MW4611.73 g/mol
LogP41.87
Rot. Bonds81

About 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide

3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide (PubChem CID 158341991) has the molecular formula C264H277Cl5N52O16 and a molecular weight of 4611.73 g/mol. Its IUPAC name is 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide.

Molecular Properties

Compound Name3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide
PubChem CID158341991
Molecular FormulaC264H277Cl5N52O16
Molecular Weight4611.73 g/mol
Exact Mass4606.09
IUPAC Name3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide
SMILESCOc1cccc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)c1O.Cc1cc(C)cc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)c1.Cc1cc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)ccc1O.Cc1ccc(CCc2n[nH]c(Cc3ccc(-n4cccc4)cc3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3ccc(Cc4ccccc4)cc3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3ccc4[nH]ncc4c3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)cn1.Cc1ccc(CNc2n[nH]c(Cc3ccc(-c4ccn[nH]4)cc3)c2C(N)=O)cc1.Cc1ccc(CNc2n[nH]c(Cc3ccc(N4CCN(C(C)C)CC4)cc3)c2C(N)=O)cc1.Cc1ncc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)cn1.NC(=O)c1c(CCc2ccc(N)cc2)n[nH]c1Cc1ccc(N2CCCCC2)cc1.NC(=O)c1c(CCc2ccc(O)cc2)n[nH]c1Cc1ccc(-n2cccn2)cc1
InChIInChI=1S/C27H27N3O.C26H34N6O.C24H29N5O.C24H24N4O.C22H22N6O.C22H21N5O2.C21H22ClN3O.C21H21N5O.C20H20ClN3O3.C20H20ClN3O2.C19H19ClN4O.C18H18ClN5O/c1-19-7-9-20(10-8-19)15-16-24-26(27(28)31)25(30-29-24)18-23-13-11-22(12-14-23)17-21-5-3-2-4-6-21;1-18(2)31-12-14-32(15-13-31)22-10-8-20(9-11-22)16-23-24(25(27)33)26(30-29-23)28-17-21-6-4-19(3)5-7-21;25-19-9-4-17(5-10-19)8-13-21-23(24(26)30)22(28-27-21)16-18-6-11-20(12-7-18)29-14-2-1-3-15-29;1-17-4-6-18(7-5-17)10-13-21-23(24(25)29)22(27-26-21)16-19-8-11-20(12-9-19)28-14-2-3-15-28;1-14-2-4-16(5-3-14)13-24-22-20(21(23)29)19(27-28-22)12-15-6-8-17(9-7-15)18-10-11-25-26-18;23-22(29)21-19(11-6-15-4-9-18(28)10-5-15)25-26-20(21)14-16-2-7-17(8-3-16)27-13-1-12-24-27;1-13-8-14(2)10-16(9-13)6-7-18-20(21(23)26)19(25-24-18)12-15-4-3-5-17(22)11-15;1-13-2-4-14(5-3-13)6-9-18-20(21(22)27)19(26-25-18)11-15-7-8-17-16(10-15)12-23-24-17;1-27-17-7-3-5-13(19(17)25)8-9-15-18(20(22)26)16(24-23-15)11-12-4-2-6-14(21)10-12;1-12-9-13(6-8-18(12)25)5-7-16-19(20(22)26)17(24-23-16)11-14-3-2-4-15(21)10-14;1-12-5-6-13(11-22-12)7-8-16-18(19(21)25)17(24-23-16)10-14-3-2-4-15(20)9-14;1-11-21-9-13(10-22-11)5-6-15-17(18(20)25)16(24-23-15)8-12-3-2-4-14(19)7-12/h2-14H,15-18H2,1H3,(H2,28,31)(H,29,30);4-11,18H,12-17H2,1-3H3,(H2,27,33)(H2,28,29,30);4-7,9-12H,1-3,8,13-16,25H2,(H2,26,30)(H,27,28);2-9,11-12,14-15H,10,13,16H2,1H3,(H2,25,29)(H,26,27);2-11H,12-13H2,1H3,(H2,23,29)(H,25,26)(H2,24,27,28);1-5,7-10,12-13,28H,6,11,14H2,(H2,23,29)(H,25,26);3-5,8-11H,6-7,12H2,1-2H3,(H2,23,26)(H,24,25);2-5,7-8,10,12H,6,9,11H2,1H3,(H2,22,27)(H,23,24)(H,25,26);2-7,10,25H,8-9,11H2,1H3,(H2,22,26)(H,23,24);2-4,6,8-10,25H,5,7,11H2,1H3,(H2,22,26)(H,23,24);2-6,9,11H,7-8,10H2,1H3,(H2,21,25)(H,23,24);2-4,7,9-10H,5-6,8H2,1H3,(H2,20,25)(H,23,24)
InChIKeyGRGURRLLBJHZRZ-UHFFFAOYSA-N
XLogP41.87
TPSA1109.74 Ų
H-Bond Donors32
H-Bond Acceptors42
Rotatable Bonds81
Heavy Atoms337
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004611.73
LogP ≤ 541.87
H-Bond Donors ≤ 532
H-Bond Acceptors ≤ 1042

Analyze 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide with MolForge

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What is the IUPAC name of 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide?
The IUPAC name of 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide (CID 158341991) is 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide.
What is the SMILES notation for 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide?
The canonical SMILES for 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide is COc1cccc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)c1O.Cc1cc(C)cc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)c1.Cc1cc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)ccc1O.Cc1ccc(CCc2n[nH]c(Cc3ccc(-n4cccc4)cc3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3ccc(Cc4ccccc4)cc3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3ccc4[nH]ncc4c3)c2C(N)=O)cc1.Cc1ccc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)cn1.Cc1ccc(CNc2n[nH]c(Cc3ccc(-c4ccn[nH]4)cc3)c2C(N)=O)cc1.Cc1ccc(CNc2n[nH]c(Cc3ccc(N4CCN(C(C)C)CC4)cc3)c2C(N)=O)cc1.Cc1ncc(CCc2n[nH]c(Cc3cccc(Cl)c3)c2C(N)=O)cn1.NC(=O)c1c(CCc2ccc(N)cc2)n[nH]c1Cc1ccc(N2CCCCC2)cc1.NC(=O)c1c(CCc2ccc(O)cc2)n[nH]c1Cc1ccc(-n2cccn2)cc1.
What is the InChIKey of 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide?
The InChIKey is GRGURRLLBJHZRZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H27N3O.C26H34N6O.C24H29N5O.C24H24N4O.C22H22N6O.C22H21N5O2.C21H22ClN3O.C21H21N5O.C20H20ClN3O3.C20H20ClN3O2.C19H19ClN4O.C18H18ClN5O/c1-19-7-9-20(10-8-19)15-16-24-26(27(28)31)25(30-29-24)18-23-13-11-22(12-14-23)17-21-5-3-2-4-6-21;1-18(2)31-12-14-32(15-13-31)22-10-8-20(9-11-22)16-23-24(25(27)33)26(30-29-23)28-17-21-6-4-19(3)5-7-21;25-19-9-4-17(5-10-19)8-13-21-23(24(26)30)22(28-27-21)16-18-6-11-20(12-7-18)29-14-2-1-3-15-29;1-17-4-6-18(7-5-17)10-13-21-23(24(25)29)22(27-26-21)16-19-8-11-20(12-9-19)28-14-2-3-15-28;1-14-2-4-16(5-3-14)13-24-22-20(21(23)29)19(27-28-22)12-15-6-8-17(9-7-15)18-10-11-25-26-18;23-22(29)21-19(11-6-15-4-9-18(28)10-5-15)25-26-20(21)14-16-2-7-17(8-3-16)27-13-1-12-24-27;1-13-8-14(2)10-16(9-13)6-7-18-20(21(23)26)19(25-24-18)12-15-4-3-5-17(22)11-15;1-13-2-4-14(5-3-13)6-9-18-20(21(22)27)19(26-25-18)11-15-7-8-17-16(10-15)12-23-24-17;1-27-17-7-3-5-13(19(17)25)8-9-15-18(20(22)26)16(24-23-15)11-12-4-2-6-14(21)10-12;1-12-9-13(6-8-18(12)25)5-7-16-19(20(22)26)17(24-23-16)11-14-3-2-4-15(21)10-14;1-12-5-6-13(11-22-12)7-8-16-18(19(21)25)17(24-23-16)10-14-3-2-4-15(20)9-14;1-11-21-9-13(10-22-11)5-6-15-17(18(20)25)16(24-23-15)8-12-3-2-4-14(19)7-12/h2-14H,15-18H2,1H3,(H2,28,31)(H,29,30);4-11,18H,12-17H2,1-3H3,(H2,27,33)(H2,28,29,30);4-7,9-12H,1-3,8,13-16,25H2,(H2,26,30)(H,27,28);2-9,11-12,14-15H,10,13,16H2,1H3,(H2,25,29)(H,26,27);2-11H,12-13H2,1H3,(H2,23,29)(H,25,26)(H2,24,27,28);1-5,7-10,12-13,28H,6,11,14H2,(H2,23,29)(H,25,26);3-5,8-11H,6-7,12H2,1-2H3,(H2,23,26)(H,24,25);2-5,7-8,10,12H,6,9,11H2,1H3,(H2,22,27)(H,23,24)(H,25,26);2-7,10,25H,8-9,11H2,1H3,(H2,22,26)(H,23,24);2-4,6,8-10,25H,5,7,11H2,1H3,(H2,22,26)(H,23,24);2-6,9,11H,7-8,10H2,1H3,(H2,21,25)(H,23,24);2-4,7,9-10H,5-6,8H2,1H3,(H2,20,25)(H,23,24).
What are the key properties of 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide?
3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide has a molecular weight of 4611.73 g/mol, XLogP of 41.87, 81 rotatable bonds, 32 hydrogen bond donors, and 42 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[2-(4-aminophenyl)ethyl]-5-[(4-piperidin-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-[(4-benzylphenyl)methyl]-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(3,5-dimethylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-hydroxy-3-methoxyphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(4-hydroxy-3-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrazole-4-carboxamide;5-[(3-chlorophenyl)methyl]-3-[2-(2-methylpyrimidin-5-yl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-hydroxyphenyl)ethyl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;5-(1H-indazol-5-ylmethyl)-3-[2-(4-methylphenyl)ethyl]-1H-pyrazole-4-carboxamide;3-[2-(4-methylphenyl)ethyl]-5-[(4-pyrrol-1-ylphenyl)methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide;3-[(4-methylphenyl)methylamino]-5-[[4-(1H-pyrazol-5-yl)phenyl]methyl]-1H-pyrazole-4-carboxamide is sourced from PubChem (CID 158341991), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).