N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine

C85H95F3N26O — CID 158342784

IUPACN-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine
SMILESCN1CCN(c2cc(Nc3cc(C4CC4)[nH]n3)ncn2)C(c2ccccc2)C1.CN1CCN(c2ccc(Nc3cc(N4CCCC4c4ccc(F)cc4)ncn3)nc2)CC1.Fc1ccc(C2CCCN2c2ncnc(Nc3cc(C4CC4)[nH]n3)c2F)cc1.c1ccc(C2COCCN2c2cc(Nc3cc(C4CC4)[nH]n3)ncn2)cc1
InChIInChI=1S/C24H28FN7.C21H25N7.C20H20F2N6.C20H22N6O/c1-30-11-13-31(14-12-30)20-8-9-22(26-16-20)29-23-15-24(28-17-27-23)32-10-2-3-21(32)18-4-6-19(25)7-5-18;1-27-9-10-28(18(13-27)16-5-3-2-4-6-16)21-12-19(22-14-23-21)24-20-11-17(25-26-20)15-7-8-15;21-14-7-5-13(6-8-14)16-2-1-9-28(16)20-18(22)19(23-11-24-20)25-17-10-15(26-27-17)12-3-4-12;1-2-4-15(5-3-1)17-12-27-9-8-26(17)20-11-18(21-13-22-20)23-19-10-16(24-25-19)14-6-7-14/h4-9,15-17,21H,2-3,10-14H2,1H3,(H,26,27,28,29);2-6,11-12,14-15,18H,7-10,13H2,1H3,(H2,22,23,24,25,26);5-8,10-12,16H,1-4,9H2,(H2,23,24,25,26,27);1-5,10-11,13-14,17H,6-9,12H2,(H2,21,22,23,24,25)
InChIKeyGRJALKPWSSEJJV-UHFFFAOYSA-N
MW1553.87 g/mol
LogP15.00
Rot. Bonds20

About N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine

N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine (PubChem CID 158342784) has the molecular formula C85H95F3N26O and a molecular weight of 1553.87 g/mol. Its IUPAC name is N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine.

Molecular Properties

Compound NameN-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine
PubChem CID158342784
Molecular FormulaC85H95F3N26O
Molecular Weight1553.87 g/mol
Exact Mass1552.81
IUPAC NameN-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine
SMILESCN1CCN(c2cc(Nc3cc(C4CC4)[nH]n3)ncn2)C(c2ccccc2)C1.CN1CCN(c2ccc(Nc3cc(N4CCCC4c4ccc(F)cc4)ncn3)nc2)CC1.Fc1ccc(C2CCCN2c2ncnc(Nc3cc(C4CC4)[nH]n3)c2F)cc1.c1ccc(C2COCCN2c2cc(Nc3cc(C4CC4)[nH]n3)ncn2)cc1
InChIInChI=1S/C24H28FN7.C21H25N7.C20H20F2N6.C20H22N6O/c1-30-11-13-31(14-12-30)20-8-9-22(26-16-20)29-23-15-24(28-17-27-23)32-10-2-3-21(32)18-4-6-19(25)7-5-18;1-27-9-10-28(18(13-27)16-5-3-2-4-6-16)21-12-19(22-14-23-21)24-20-11-17(25-26-20)15-7-8-15;21-14-7-5-13(6-8-14)16-2-1-9-28(16)20-18(22)19(23-11-24-20)25-17-10-15(26-27-17)12-3-4-12;1-2-4-15(5-3-1)17-12-27-9-8-26(17)20-11-18(21-13-22-20)23-19-10-16(24-25-19)14-6-7-14/h4-9,15-17,21H,2-3,10-14H2,1H3,(H,26,27,28,29);2-6,11-12,14-15,18H,7-10,13H2,1H3,(H2,22,23,24,25,26);5-8,10-12,16H,1-4,9H2,(H2,23,24,25,26,27);1-5,10-11,13-14,17H,6-9,12H2,(H2,21,22,23,24,25)
InChIKeyGRJALKPWSSEJJV-UHFFFAOYSA-N
XLogP15.00
TPSA282.08 Ų
H-Bond Donors7
H-Bond Acceptors24
Rotatable Bonds20
Heavy Atoms115
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001553.87
LogP ≤ 515.00
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1024

Analyze N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine with MolForge

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Launch Full Analysis

Related Compounds

1-N-cyclobutyl-1-N,3-dimethyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;1-cyclopropyl-3-methyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinolin-6-amine;1-ethenyl-3-methyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinolin-6-amine;1-N-(2-methoxyethyl)-3-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-methyl-1-prop-2-enyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinolin-6-amine;3-methyl-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1-(1,1,1-trifluoropropan-2-yl)isoquinolin-6-amine
CID 157446494
6-(difluoromethyl)-3-[6-[1-(oxan-4-yl)pyrazol-4-yl]pyrimidin-4-yl]imidazo[1,2-b]pyridazine;3-[6-[2,5-dimethyl-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-b]pyridazine;3-[6-[2-methyl-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-b]pyridazine;3-[6-[3-methyl-2-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-b]pyridazine;3-[6-[1-(oxan-4-yl)pyrazol-4-yl]pyrimidin-4-yl]-6-(trifluoromethyl)imidazo[1,2-b]pyridazine
CID 158034812
bis(5-[5-[(1R,5S)-3-imidazol-1-yl-6-bicyclo[3.1.0]hexanyl]-1-propan-2-ylpyrazol-3-yl]-3-(trifluoromethyl)pyridin-2-amine);5-[5-[(1S,5R)-3-[4-(oxetan-3-yl)piperazin-1-yl]-6-bicyclo[3.1.0]hexanyl]-1-propan-2-ylpyrazol-3-yl]-3-(trifluoromethyl)pyridin-2-amine
CID 158441876
7-[1-(2,2-difluoro-3-morpholin-4-ylpropyl)pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-(1,3-dimethylpyrazol-4-yl)-N-(5-ethylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-(1,3-dimethylpyrazol-4-yl)-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[ethyl(methyl)amino]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-methyl-3-(6-methyl-3-pyridinyl)pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N-(5-propan-2-ylpyridazin-3-yl)-7-[1-(pyrimidin-5-ylmethyl)pyrazol-4-yl]-1,5-naphthyridin-2-amine
CID 159943380
N-[6-but-3-enyl-2-[2-(trifluoromethyl)phenyl]pyrimidin-4-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine;N-[6-ethyl-2-[2-(trifluoromethyl)phenyl]pyrimidin-4-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine;5-fluoro-N-[6-methyl-2-[2-(trifluoromethyl)phenyl]pyrimidin-4-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine;N-[6-(3-morpholin-4-ylpropyl)-2-[2-(trifluoromethyl)phenyl]pyrimidin-4-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine
CID 160435668
N-(6-chloro-2-cyclohexylpyrimidin-4-yl)-5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-amine;N-(2-cyclohexyl-5,6-dimethylpyrimidin-4-yl)-5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-amine;N-[2-cyclohexyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-5-fluoro-1H-indazol-3-amine;N-[2-(4,4-difluorocyclohexyl)-6-methylpyrimidin-4-yl]-5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-amine;N-[5,6-dimethyl-2-(oxan-4-yl)pyrimidin-4-yl]-5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-amine;molecular hydrogen
CID 161345122
N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-(5-morpholin-4-ylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-(5-piperidin-1-ylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-(5-pyrazol-1-ylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine
CID 161535715
3-[6-(4-methylpiperazin-1-yl)-2-pyridinyl]-2H-pyrazolo[3,4-b]pyridine;4-[6-(2H-pyrazolo[3,4-b]pyridin-3-yl)-2-pyridinyl]morpholine;3-[6-[3-(2,2,2-trifluoroethyl)piperazin-1-yl]-2-pyridinyl]-2H-pyrazolo[3,4-b]pyridine;3-[6-[3-(trifluoromethyl)piperazin-1-yl]-2-pyridinyl]-2H-pyrazolo[3,4-b]pyridine
CID 161863696
4-[5-(1,3-dimethylpyrazol-4-yl)-2-[[(2S)-1-methoxypropan-2-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-7-yl]cyclohexan-1-ol;4-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-2-[[(2S)-4,4,4-trifluorobutan-2-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-7-yl]cyclohexan-1-ol;4-[2-[[(2S)-1-methoxypropan-2-yl]amino]-5-(2-piperidin-1-yl-4-pyridinyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]cyclohexan-1-ol
CID 162030654
1-cyclohexyl-3-[4-[[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]cyclohexyl]-2-(2,2,2-trifluoroethyl)guanidine;1-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]cyclohexyl]-2-methyl-3-[3-(trifluoromethyl)phenyl]guanidine;1-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]cyclohexyl]-3-(oxan-4-yl)-2-(2,2,2-trifluoroethyl)guanidine;2-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]cyclohexyl]-1-[3-(trifluoromethyl)phenyl]guanidine;1-[(1R,3R)-3-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]cyclopentyl]-3-[3-(trifluoromethyl)phenyl]urea
CID 163742895
5-fluoro-N-[(E)-[5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]-4-(5-methyl-3-pyridinyl)pyrimidin-2-amine;5-fluoro-2-N-[(E)-[5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]-4-N-(2-morpholin-4-ylethyl)pyrimidine-2,4-diamine;bis(5-fluoro-N-[(E)-[5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]-4-pyridin-3-ylpyrimidin-2-amine)
CID 172938703
5-fluoro-N-[(E)-[5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]-4-(5-methyl-3-pyridinyl)pyrimidin-2-amine;5-fluoro-2-N-[(E)-[5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]-4-N-(2-morpholin-4-ylethyl)pyrimidine-2,4-diamine;5-fluoro-N-[(E)-[5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]-4-pyridin-3-ylpyrimidin-2-amine;4-methyl-N-[(E)-[5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]-6-pyridin-3-ylpyrimidin-2-amine
CID 172944459

Frequently Asked Questions

What is the IUPAC name of N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine?
The IUPAC name of N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine (CID 158342784) is N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine.
What is the SMILES notation for N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine?
The canonical SMILES for N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine is CN1CCN(c2cc(Nc3cc(C4CC4)[nH]n3)ncn2)C(c2ccccc2)C1.CN1CCN(c2ccc(Nc3cc(N4CCCC4c4ccc(F)cc4)ncn3)nc2)CC1.Fc1ccc(C2CCCN2c2ncnc(Nc3cc(C4CC4)[nH]n3)c2F)cc1.c1ccc(C2COCCN2c2cc(Nc3cc(C4CC4)[nH]n3)ncn2)cc1.
What is the InChIKey of N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine?
The InChIKey is GRJALKPWSSEJJV-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H28FN7.C21H25N7.C20H20F2N6.C20H22N6O/c1-30-11-13-31(14-12-30)20-8-9-22(26-16-20)29-23-15-24(28-17-27-23)32-10-2-3-21(32)18-4-6-19(25)7-5-18;1-27-9-10-28(18(13-27)16-5-3-2-4-6-16)21-12-19(22-14-23-21)24-20-11-17(25-26-20)15-7-8-15;21-14-7-5-13(6-8-14)16-2-1-9-28(16)20-18(22)19(23-11-24-20)25-17-10-15(26-27-17)12-3-4-12;1-2-4-15(5-3-1)17-12-27-9-8-26(17)20-11-18(21-13-22-20)23-19-10-16(24-25-19)14-6-7-14/h4-9,15-17,21H,2-3,10-14H2,1H3,(H,26,27,28,29);2-6,11-12,14-15,18H,7-10,13H2,1H3,(H2,22,23,24,25,26);5-8,10-12,16H,1-4,9H2,(H2,23,24,25,26,27);1-5,10-11,13-14,17H,6-9,12H2,(H2,21,22,23,24,25).
What are the key properties of N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine?
N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine has a molecular weight of 1553.87 g/mol, XLogP of 15.00, 20 rotatable bonds, 7 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for N-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoro-6-[2-(4-fluorophenyl)pyrrolidin-1-yl]pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methyl-2-phenylpiperazin-1-yl)pyrimidin-4-amine;N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(3-phenylmorpholin-4-yl)pyrimidin-4-amine;6-[2-(4-fluorophenyl)pyrrolidin-1-yl]-N-[5-(4-methylpiperazin-1-yl)-2-pyridinyl]pyrimidin-4-amine is sourced from PubChem (CID 158342784), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).