N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide

C108H109F4N37O4S5 — CID 158343076

About N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide

N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide (PubChem CID 158343076) has the molecular formula C108H109F4N37O4S5 and a molecular weight of 2225.64 g/mol. Its IUPAC name is N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide.

Molecular Properties

• Compound Name: N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide
• PubChem CID: 158343076
• Molecular Formula: C108H109F4N37O4S5
• Molecular Weight: 2225.64 g/mol
• Exact Mass: 2223.80
• IUPAC Name: N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide
• SMILES: Cc1cn2c(-c3ccn(CC(=O)Nc4ccncc4F)n3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1.Cc1cn2c(-c3ccnc(CC(=O)Nc4ccncc4F)c3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1.Cc1cn2c(-c3cncc(CC(=O)Nc4ccncc4F)c3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1.Cc1cn2c(-c3ncc(CC(=O)Nc4ccncc4F)s3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1
• InChI: InChI=1S/2C28H28FN9OS.C26H27FN10OS.C26H26FN9OS2/c1-18-16-38-24(19-5-8-31-20(11-19)12-25(39)34-23-6-7-30-14-22(23)29)15-32-28(38)27(33-18)35-26-13-21(36-40-26)17-37-9-3-2-4-10-37;1-18-16-38-24(20-9-19(12-31-13-20)10-25(39)34-23-5-6-30-14-22(23)29)15-32-28(38)27(33-18)35-26-11-21(36-40-26)17-37-7-3-2-4-8-37;1-17-14-37-22(21-6-10-36(33-21)16-23(38)31-20-5-7-28-12-19(20)27)13-29-26(37)25(30-17)32-24-11-18(34-39-24)15-35-8-3-2-4-9-35;1-16-14-36-21(26-30-11-18(38-26)10-22(37)32-20-5-6-28-12-19(20)27)13-29-25(36)24(31-16)33-23-9-17(34-39-23)15-35-7-3-2-4-8-35/h5-8,11,13-16H,2-4,9-10,12,17H2,1H3,(H,33,35)(H,30,34,39);5-6,9,11-16H,2-4,7-8,10,17H2,1H3,(H,33,35)(H,30,34,39);5-7,10-14H,2-4,8-9,15-16H2,1H3,(H,30,32)(H,28,31,38);5-6,9,11-14H,2-4,7-8,10,15H2,1H3,(H,31,33)(H,28,32,37)
• InChIKey: GRJVMVHWBKMSJS-UHFFFAOYSA-N
• XLogP: 19.32
• TPSA: 457.85 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 42
• Rotatable Bonds: 32
• Heavy Atoms: 158
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2225.64
LogP ≤ 5	19.32
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	42

Frequently Asked Questions

What is the IUPAC name of N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide?

The IUPAC name of N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide (CID 158343076) is N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide.

What is the SMILES notation for N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide?

The canonical SMILES for N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide is Cc1cn2c(-c3ccn(CC(=O)Nc4ccncc4F)n3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1.Cc1cn2c(-c3ccnc(CC(=O)Nc4ccncc4F)c3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1.Cc1cn2c(-c3cncc(CC(=O)Nc4ccncc4F)c3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1.Cc1cn2c(-c3ncc(CC(=O)Nc4ccncc4F)s3)cnc2c(Nc2cc(CN3CCCCC3)ns2)n1.

What is the InChIKey of N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide?

The InChIKey is GRJVMVHWBKMSJS-UHFFFAOYSA-N. The full InChI is InChI=1S/2C28H28FN9OS.C26H27FN10OS.C26H26FN9OS2/c1-18-16-38-24(19-5-8-31-20(11-19)12-25(39)34-23-6-7-30-14-22(23)29)15-32-28(38)27(33-18)35-26-13-21(36-40-26)17-37-9-3-2-4-10-37;1-18-16-38-24(20-9-19(12-31-13-20)10-25(39)34-23-5-6-30-14-22(23)29)15-32-28(38)27(33-18)35-26-11-21(36-40-26)17-37-7-3-2-4-8-37;1-17-14-37-22(21-6-10-36(33-21)16-23(38)31-20-5-7-28-12-19(20)27)13-29-26(37)25(30-17)32-24-11-18(34-39-24)15-35-8-3-2-4-9-35;1-16-14-36-21(26-30-11-18(38-26)10-22(37)32-20-5-6-28-12-19(20)27)13-29-25(36)24(31-16)33-23-9-17(34-39-23)15-35-7-3-2-4-8-35/h5-8,11,13-16H,2-4,9-10,12,17H2,1H3,(H,33,35)(H,30,34,39);5-6,9,11-16H,2-4,7-8,10,17H2,1H3,(H,33,35)(H,30,34,39);5-7,10-14H,2-4,8-9,15-16H2,1H3,(H,30,32)(H,28,31,38);5-6,9,11-14H,2-4,7-8,10,15H2,1H3,(H,31,33)(H,28,32,37).

What are the key properties of N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide?

N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide has a molecular weight of 2225.64 g/mol, XLogP of 19.32, 32 rotatable bonds, 8 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for N-(3-fluoro-4-pyridinyl)-2-[3-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]pyrazol-1-yl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[4-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-2-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[5-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-3-pyridinyl]acetamide;N-(3-fluoro-4-pyridinyl)-2-[2-[6-methyl-8-[[3-(piperidin-1-ylmethyl)-1,2-thiazol-5-yl]amino]imidazo[1,2-a]pyrazin-3-yl]-1,3-thiazol-5-yl]acetamide is sourced from PubChem (CID 158343076), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).