N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine

C96H107F10N29O10S4 — CID 158347580

About N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine

N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine (PubChem CID 158347580) has the molecular formula C96H107F10N29O10S4 and a molecular weight of 2145.35 g/mol. Its IUPAC name is N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine.

Molecular Properties

• Compound Name: N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine
• PubChem CID: 158347580
• Molecular Formula: C96H107F10N29O10S4
• Molecular Weight: 2145.35 g/mol
• Exact Mass: 2143.75
• IUPAC Name: N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine
• SMILES: CC(=O)N1CCN(c2ccnc(-c3cnc4ccc(C(F)F)nn34)c2)CC1.CS(=O)(=O)CCC1CCCN(c2cc(-c3cnc4ccc(C(F)F)nn34)ccn2)C1.CS(=O)(=O)N1CC2(CN(c3cc(-c4cnc5ccc(C(F)F)nn45)ccn3)CCO2)C1.CS(=O)(=O)NCC1CCCN(c2ccnc(-c3cnc4ccc(C(F)F)nn34)c2)C1.Cc1cc(-c2cnc3ccc(C(F)F)nn23)cc(N2CCCC(CNS(C)(=O)=O)C2)n1
• InChI: InChI=1S/C20H24F2N6O2S.C20H23F2N5O2S.C19H20F2N6O3S.C19H22F2N6O2S.C18H18F2N6O/c1-13-8-15(17-11-23-18-6-5-16(20(21)22)26-28(17)18)9-19(25-13)27-7-3-4-14(12-27)10-24-31(2,29)30;1-30(28,29)10-7-14-3-2-9-26(13-14)19-11-15(6-8-23-19)17-12-24-18-5-4-16(20(21)22)25-27(17)18;1-31(28,29)26-11-19(12-26)10-25(6-7-30-19)17-8-13(4-5-22-17)15-9-23-16-3-2-14(18(20)21)24-27(15)16;1-30(28,29)24-10-13-3-2-8-26(12-13)14-6-7-22-16(9-14)17-11-23-18-5-4-15(19(20)21)25-27(17)18;1-12(27)24-6-8-25(9-7-24)13-4-5-21-15(10-13)16-11-22-17-3-2-14(18(19)20)23-26(16)17/h5-6,8-9,11,14,20,24H,3-4,7,10,12H2,1-2H3;4-6,8,11-12,14,20H,2-3,7,9-10,13H2,1H3;2-5,8-9,18H,6-7,10-12H2,1H3;4-7,9,11,13,19,24H,2-3,8,10,12H2,1H3;2-5,10-11,18H,6-9H2,1H3
• InChIKey: GRXPPSHUVSEWSB-UHFFFAOYSA-N
• XLogP: 12.65
• TPSA: 425.00 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 35
• Rotatable Bonds: 25
• Heavy Atoms: 149
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2145.35
LogP ≤ 5	12.65
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine?

The IUPAC name of N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine (CID 158347580) is N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine.

What is the SMILES notation for N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine?

The canonical SMILES for N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine is CC(=O)N1CCN(c2ccnc(-c3cnc4ccc(C(F)F)nn34)c2)CC1.CS(=O)(=O)CCC1CCCN(c2cc(-c3cnc4ccc(C(F)F)nn34)ccn2)C1.CS(=O)(=O)N1CC2(CN(c3cc(-c4cnc5ccc(C(F)F)nn45)ccn3)CCO2)C1.CS(=O)(=O)NCC1CCCN(c2ccnc(-c3cnc4ccc(C(F)F)nn34)c2)C1.Cc1cc(-c2cnc3ccc(C(F)F)nn23)cc(N2CCCC(CNS(C)(=O)=O)C2)n1.

What is the InChIKey of N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine?

The InChIKey is GRXPPSHUVSEWSB-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H24F2N6O2S.C20H23F2N5O2S.C19H20F2N6O3S.C19H22F2N6O2S.C18H18F2N6O/c1-13-8-15(17-11-23-18-6-5-16(20(21)22)26-28(17)18)9-19(25-13)27-7-3-4-14(12-27)10-24-31(2,29)30;1-30(28,29)10-7-14-3-2-9-26(13-14)19-11-15(6-8-23-19)17-12-24-18-5-4-16(20(21)22)25-27(17)18;1-31(28,29)26-11-19(12-26)10-25(6-7-30-19)17-8-13(4-5-22-17)15-9-23-16-3-2-14(18(20)21)24-27(15)16;1-30(28,29)24-10-13-3-2-8-26(12-13)14-6-7-22-16(9-14)17-11-23-18-5-4-15(19(20)21)25-27(17)18;1-12(27)24-6-8-25(9-7-24)13-4-5-21-15(10-13)16-11-22-17-3-2-14(18(19)20)23-26(16)17/h5-6,8-9,11,14,20,24H,3-4,7,10,12H2,1-2H3;4-6,8,11-12,14,20H,2-3,7,9-10,13H2,1H3;2-5,8-9,18H,6-7,10-12H2,1H3;4-7,9,11,13,19,24H,2-3,8,10,12H2,1H3;2-5,10-11,18H,6-9H2,1H3.

What are the key properties of N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine?

N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine has a molecular weight of 2145.35 g/mol, XLogP of 12.65, 25 rotatable bonds, 2 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for N-[[1-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-6-methyl-2-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;8-[4-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-2-methylsulfonyl-5-oxa-2,8-diazaspiro[3.5]nonane;1-[4-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperazin-1-yl]ethanone;N-[[1-[2-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]-4-pyridinyl]piperidin-3-yl]methyl]methanesulfonamide;6-(difluoromethyl)-3-[2-[3-(2-methylsulfonylethyl)piperidin-1-yl]-4-pyridinyl]imidazo[1,2-b]pyridazine is sourced from PubChem (CID 158347580), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).