2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide

C111H87ClF4N14O5 — CID 158348744

About 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide

2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide (PubChem CID 158348744) has the molecular formula C111H87ClF4N14O5 and a molecular weight of 1808.45 g/mol. Its IUPAC name is 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide.

Molecular Properties

• Compound Name: 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
• PubChem CID: 158348744
• Molecular Formula: C111H87ClF4N14O5
• Molecular Weight: 1808.45 g/mol
• Exact Mass: 1806.66
• IUPAC Name: 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
• SMILES: Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5)cnc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5)cnc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(C)nc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(CO)nc34)ccc2Cl)cc1
• InChI: InChI=1S/C28H21F3N4O.C28H22FN3O.C28H23N3O.C27H21ClN4O2/c1-17-7-10-21(11-8-17)34-27(36)23-15-19(9-12-24(23)28(29,30)31)22-6-4-14-35-25(18(2)33-26(22)35)20-5-3-13-32-16-20;1-18-8-12-23(13-9-18)31-28(33)25-16-20(11-10-19(25)2)24-7-4-14-32-26(17-30-27(24)32)21-5-3-6-22(29)15-21;1-19-10-14-23(15-11-19)30-28(32)25-17-22(13-12-20(25)2)24-9-6-16-31-26(18-29-27(24)31)21-7-4-3-5-8-21;1-17-6-9-20(10-7-17)30-27(34)22-14-18(8-11-23(22)28)21-5-3-13-32-25(19-4-2-12-29-15-19)24(16-33)31-26(21)32/h3-16H,1-2H3,(H,34,36);3-17H,1-2H3,(H,31,33);3-18H,1-2H3,(H,30,32);2-15,33H,16H2,1H3,(H,30,34)
• InChIKey: GSBBURJDNWKYLV-UHFFFAOYSA-N
• XLogP: 25.93
• TPSA: 231.61 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 15
• Rotatable Bonds: 17
• Heavy Atoms: 135
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1808.45
LogP ≤ 5	25.93
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	15

Frequently Asked Questions

What is the IUPAC name of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?

The IUPAC name of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide (CID 158348744) is 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide.

What is the SMILES notation for 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?

The canonical SMILES for 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide is Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5)cnc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5)cnc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(C)nc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccnc5)c(CO)nc34)ccc2Cl)cc1.

What is the InChIKey of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?

The InChIKey is GSBBURJDNWKYLV-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H21F3N4O.C28H22FN3O.C28H23N3O.C27H21ClN4O2/c1-17-7-10-21(11-8-17)34-27(36)23-15-19(9-12-24(23)28(29,30)31)22-6-4-14-35-25(18(2)33-26(22)35)20-5-3-13-32-16-20;1-18-8-12-23(13-9-18)31-28(33)25-16-20(11-10-19(25)2)24-7-4-14-32-26(17-30-27(24)32)21-5-3-6-22(29)15-21;1-19-10-14-23(15-11-19)30-28(32)25-17-22(13-12-20(25)2)24-9-6-16-31-26(18-29-27(24)31)21-7-4-3-5-8-21;1-17-6-9-20(10-7-17)30-27(34)22-14-18(8-11-23(22)28)21-5-3-13-32-25(19-4-2-12-29-15-19)24(16-33)31-26(21)32/h3-16H,1-2H3,(H,34,36);3-17H,1-2H3,(H,31,33);3-18H,1-2H3,(H,30,32);2-15,33H,16H2,1H3,(H,30,34).

What are the key properties of 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide?

2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide has a molecular weight of 1808.45 g/mol, XLogP of 25.93, 17 rotatable bonds, 5 hydrogen bond donors, and 15 hydrogen bond acceptors.

Where does this data come from?

All data for 2-chloro-5-[2-(hydroxymethyl)-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)benzamide;2-methyl-N-(4-methylphenyl)-5-(3-phenylimidazo[1,2-a]pyridin-8-yl)benzamide;N-(4-methylphenyl)-5-(2-methyl-3-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide is sourced from PubChem (CID 158348744), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).