N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide

C244H295BrF24N42O20 — CID 158349609

IUPACN-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide
SMILESCC(C)(C)CC(=O)Nc1nc2c(C(F)(F)F)cc(Br)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2c(F)cc(C(O)(CF)CF)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)c(F)c2n1C1(C)CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(N3CC(F)(F)C3)c(F)c2n1C1CCC1.CC(O)(CC(=O)Nc1nc2cc(F)c(C#N)cc2n1C1(C)CCC1)c1ccccc1F.CC(O)(CC(=O)Nc1nc2ccc(C#N)cc2n1CC(F)(F)F)c1ccccc1F.CC1(CC(=O)Nc2nc3c(F)cc(C(C)(C)O)cc3n2C2(C)CCC2)CC1.CCC(C)(CF)CC(=O)Nc1nc2c(F)cc(C(C)(C)O)cc2n1C1(C)CCC1.CN(C)c1ccc2nc(NC(=O)CC(C)(O)c3ccccc3)n(C3CCC3)c2c1F.COc1cccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c12.[C-]#[N+]c1cc(F)c2nc(NC(=O)CC(C)(C)C3CC3)n(C3CCC3)c2c1.[C-]#[N+]c1ccc2nc(NC(=O)CC(C)(C)C(F)(F)F)n(C(C)(C)C)c2c1
InChIInChI=1S/C23H22F2N4O2.C23H27FN4O2.C22H31F2N3O2.C21H28FN3O2.C21H30FN3O2.C20H16F4N4O2.C20H25F3N4O.C20H26F3N3O2.C20H23FN4O.C18H21BrF3N3O.C18H21F3N4O.C18H25N3O2/c1-22(8-5-9-22)29-19-10-14(13-26)17(25)11-18(19)27-21(29)28-20(30)12-23(2,31)15-6-3-4-7-16(15)24;1-23(30,15-8-5-4-6-9-15)14-19(29)26-22-25-17-12-13-18(27(2)3)20(24)21(17)28(22)16-10-7-11-16;1-6-21(4,13-23)12-17(28)25-19-26-18-15(24)10-14(20(2,3)29)11-16(18)27(19)22(5)8-7-9-22;1-19(2,27)13-10-14(22)17-15(11-13)25(21(4)6-5-7-21)18(24-17)23-16(26)12-20(3)8-9-20;1-19(2,3)12-15(26)24-18-23-14-9-8-13(20(4,5)27)16(22)17(14)25(18)21(6)10-7-11-21;1-19(30,13-4-2-3-5-14(13)21)9-17(29)27-18-26-15-7-6-12(10-25)8-16(15)28(18)11-20(22,23)24;1-19(2,3)9-15(28)25-18-24-13-7-8-14(26-10-20(22,23)11-26)16(21)17(13)27(18)12-5-4-6-12;1-19(2,3)9-16(27)24-18-25-17-14(23)7-12(20(28,10-21)11-22)8-15(17)26(18)13-5-4-6-13;1-20(2,12-7-8-12)11-17(26)23-19-24-18-15(21)9-13(22-3)10-16(18)25(19)14-5-4-6-14;1-17(2,3)9-14(26)23-16-24-15-12(18(20,21)22)7-10(19)8-13(15)25(16)11-5-4-6-11;1-16(2,3)25-13-9-11(22-6)7-8-12(13)23-15(25)24-14(26)10-17(4,5)18(19,20)21;1-18(2,3)11-15(22)20-17-19-13-9-6-10-14(23-4)16(13)21(17)12-7-5-8-12/h3-4,6-7,10-11,31H,5,8-9,12H2,1-2H3,(H,27,28,30);4-6,8-9,12-13,16,30H,7,10-11,14H2,1-3H3,(H,25,26,29);10-11,29H,6-9,12-13H2,1-5H3,(H,25,26,28);10-11,27H,5-9,12H2,1-4H3,(H,23,24,26);8-9,27H,7,10-12H2,1-6H3,(H,23,24,26);2-8,30H,9,11H2,1H3,(H,26,27,29);7-8,12H,4-6,9-11H2,1-3H3,(H,24,25,28);7-8,13,28H,4-6,9-11H2,1-3H3,(H,24,25,27);9-10,12,14H,4-8,11H2,1-2H3,(H,23,24,26);7-8,11H,4-6,9H2,1-3H3,(H,23,24,26);7-9H,10H2,1-5H3,(H,23,24,26);6,9-10,12H,5,7-8,11H2,1-4H3,(H,19,20,22)
InChIKeyGSDOSAFREDQWSG-UHFFFAOYSA-N
MW4672.17 g/mol
LogP56.16
Rot. Bonds57

About N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide

N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide (PubChem CID 158349609) has the molecular formula C244H295BrF24N42O20 and a molecular weight of 4672.17 g/mol. Its IUPAC name is N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide.

Molecular Properties

Compound NameN-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide
PubChem CID158349609
Molecular FormulaC244H295BrF24N42O20
Molecular Weight4672.17 g/mol
Exact Mass4668.22
IUPAC NameN-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide
SMILESCC(C)(C)CC(=O)Nc1nc2c(C(F)(F)F)cc(Br)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2c(F)cc(C(O)(CF)CF)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)c(F)c2n1C1(C)CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(N3CC(F)(F)C3)c(F)c2n1C1CCC1.CC(O)(CC(=O)Nc1nc2cc(F)c(C#N)cc2n1C1(C)CCC1)c1ccccc1F.CC(O)(CC(=O)Nc1nc2ccc(C#N)cc2n1CC(F)(F)F)c1ccccc1F.CC1(CC(=O)Nc2nc3c(F)cc(C(C)(C)O)cc3n2C2(C)CCC2)CC1.CCC(C)(CF)CC(=O)Nc1nc2c(F)cc(C(C)(C)O)cc2n1C1(C)CCC1.CN(C)c1ccc2nc(NC(=O)CC(C)(O)c3ccccc3)n(C3CCC3)c2c1F.COc1cccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c12.[C-]#[N+]c1cc(F)c2nc(NC(=O)CC(C)(C)C3CC3)n(C3CCC3)c2c1.[C-]#[N+]c1ccc2nc(NC(=O)CC(C)(C)C(F)(F)F)n(C(C)(C)C)c2c1
InChIInChI=1S/C23H22F2N4O2.C23H27FN4O2.C22H31F2N3O2.C21H28FN3O2.C21H30FN3O2.C20H16F4N4O2.C20H25F3N4O.C20H26F3N3O2.C20H23FN4O.C18H21BrF3N3O.C18H21F3N4O.C18H25N3O2/c1-22(8-5-9-22)29-19-10-14(13-26)17(25)11-18(19)27-21(29)28-20(30)12-23(2,31)15-6-3-4-7-16(15)24;1-23(30,15-8-5-4-6-9-15)14-19(29)26-22-25-17-12-13-18(27(2)3)20(24)21(17)28(22)16-10-7-11-16;1-6-21(4,13-23)12-17(28)25-19-26-18-15(24)10-14(20(2,3)29)11-16(18)27(19)22(5)8-7-9-22;1-19(2,27)13-10-14(22)17-15(11-13)25(21(4)6-5-7-21)18(24-17)23-16(26)12-20(3)8-9-20;1-19(2,3)12-15(26)24-18-23-14-9-8-13(20(4,5)27)16(22)17(14)25(18)21(6)10-7-11-21;1-19(30,13-4-2-3-5-14(13)21)9-17(29)27-18-26-15-7-6-12(10-25)8-16(15)28(18)11-20(22,23)24;1-19(2,3)9-15(28)25-18-24-13-7-8-14(26-10-20(22,23)11-26)16(21)17(13)27(18)12-5-4-6-12;1-19(2,3)9-16(27)24-18-25-17-14(23)7-12(20(28,10-21)11-22)8-15(17)26(18)13-5-4-6-13;1-20(2,12-7-8-12)11-17(26)23-19-24-18-15(21)9-13(22-3)10-16(18)25(19)14-5-4-6-14;1-17(2,3)9-14(26)23-16-24-15-12(18(20,21)22)7-10(19)8-13(15)25(16)11-5-4-6-11;1-16(2,3)25-13-9-11(22-6)7-8-12(13)23-15(25)24-14(26)10-17(4,5)18(19,20)21;1-18(2,3)11-15(22)20-17-19-13-9-6-10-14(23-4)16(13)21(17)12-7-5-8-12/h3-4,6-7,10-11,31H,5,8-9,12H2,1-2H3,(H,27,28,30);4-6,8-9,12-13,16,30H,7,10-11,14H2,1-3H3,(H,25,26,29);10-11,29H,6-9,12-13H2,1-5H3,(H,25,26,28);10-11,27H,5-9,12H2,1-4H3,(H,23,24,26);8-9,27H,7,10-12H2,1-6H3,(H,23,24,26);2-8,30H,9,11H2,1H3,(H,26,27,29);7-8,12H,4-6,9-11H2,1-3H3,(H,24,25,28);7-8,13,28H,4-6,9-11H2,1-3H3,(H,24,25,27);9-10,12,14H,4-8,11H2,1-2H3,(H,23,24,26);7-8,11H,4-6,9H2,1-3H3,(H,23,24,26);7-9H,10H2,1-5H3,(H,23,24,26);6,9-10,12H,5,7-8,11H2,1-4H3,(H,19,20,22)
InChIKeyGSDOSAFREDQWSG-UHFFFAOYSA-N
XLogP56.16
TPSA776.66 Ų
H-Bond Donors19
H-Bond Acceptors48
Rotatable Bonds57
Heavy Atoms331
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004672.17
LogP ≤ 556.16
H-Bond Donors ≤ 519
H-Bond Acceptors ≤ 1048

Analyze N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide with MolForge

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What is the IUPAC name of N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide?
The IUPAC name of N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide (CID 158349609) is N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide.
What is the SMILES notation for N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide?
The canonical SMILES for N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide is CC(C)(C)CC(=O)Nc1nc2c(C(F)(F)F)cc(Br)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2c(F)cc(C(O)(CF)CF)cc2n1C1CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)c(F)c2n1C1(C)CCC1.CC(C)(C)CC(=O)Nc1nc2ccc(N3CC(F)(F)C3)c(F)c2n1C1CCC1.CC(O)(CC(=O)Nc1nc2cc(F)c(C#N)cc2n1C1(C)CCC1)c1ccccc1F.CC(O)(CC(=O)Nc1nc2ccc(C#N)cc2n1CC(F)(F)F)c1ccccc1F.CC1(CC(=O)Nc2nc3c(F)cc(C(C)(C)O)cc3n2C2(C)CCC2)CC1.CCC(C)(CF)CC(=O)Nc1nc2c(F)cc(C(C)(C)O)cc2n1C1(C)CCC1.CN(C)c1ccc2nc(NC(=O)CC(C)(O)c3ccccc3)n(C3CCC3)c2c1F.COc1cccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c12.[C-]#[N+]c1cc(F)c2nc(NC(=O)CC(C)(C)C3CC3)n(C3CCC3)c2c1.[C-]#[N+]c1ccc2nc(NC(=O)CC(C)(C)C(F)(F)F)n(C(C)(C)C)c2c1.
What is the InChIKey of N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide?
The InChIKey is GSDOSAFREDQWSG-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H22F2N4O2.C23H27FN4O2.C22H31F2N3O2.C21H28FN3O2.C21H30FN3O2.C20H16F4N4O2.C20H25F3N4O.C20H26F3N3O2.C20H23FN4O.C18H21BrF3N3O.C18H21F3N4O.C18H25N3O2/c1-22(8-5-9-22)29-19-10-14(13-26)17(25)11-18(19)27-21(29)28-20(30)12-23(2,31)15-6-3-4-7-16(15)24;1-23(30,15-8-5-4-6-9-15)14-19(29)26-22-25-17-12-13-18(27(2)3)20(24)21(17)28(22)16-10-7-11-16;1-6-21(4,13-23)12-17(28)25-19-26-18-15(24)10-14(20(2,3)29)11-16(18)27(19)22(5)8-7-9-22;1-19(2,27)13-10-14(22)17-15(11-13)25(21(4)6-5-7-21)18(24-17)23-16(26)12-20(3)8-9-20;1-19(2,3)12-15(26)24-18-23-14-9-8-13(20(4,5)27)16(22)17(14)25(18)21(6)10-7-11-21;1-19(30,13-4-2-3-5-14(13)21)9-17(29)27-18-26-15-7-6-12(10-25)8-16(15)28(18)11-20(22,23)24;1-19(2,3)9-15(28)25-18-24-13-7-8-14(26-10-20(22,23)11-26)16(21)17(13)27(18)12-5-4-6-12;1-19(2,3)9-16(27)24-18-25-17-14(23)7-12(20(28,10-21)11-22)8-15(17)26(18)13-5-4-6-13;1-20(2,12-7-8-12)11-17(26)23-19-24-18-15(21)9-13(22-3)10-16(18)25(19)14-5-4-6-14;1-17(2,3)9-14(26)23-16-24-15-12(18(20,21)22)7-10(19)8-13(15)25(16)11-5-4-6-11;1-16(2,3)25-13-9-11(22-6)7-8-12(13)23-15(25)24-14(26)10-17(4,5)18(19,20)21;1-18(2,3)11-15(22)20-17-19-13-9-6-10-14(23-4)16(13)21(17)12-7-5-8-12/h3-4,6-7,10-11,31H,5,8-9,12H2,1-2H3,(H,27,28,30);4-6,8-9,12-13,16,30H,7,10-11,14H2,1-3H3,(H,25,26,29);10-11,29H,6-9,12-13H2,1-5H3,(H,25,26,28);10-11,27H,5-9,12H2,1-4H3,(H,23,24,26);8-9,27H,7,10-12H2,1-6H3,(H,23,24,26);2-8,30H,9,11H2,1H3,(H,26,27,29);7-8,12H,4-6,9-11H2,1-3H3,(H,24,25,28);7-8,13,28H,4-6,9-11H2,1-3H3,(H,24,25,27);9-10,12,14H,4-8,11H2,1-2H3,(H,23,24,26);7-8,11H,4-6,9H2,1-3H3,(H,23,24,26);7-9H,10H2,1-5H3,(H,23,24,26);6,9-10,12H,5,7-8,11H2,1-4H3,(H,19,20,22).
What are the key properties of N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide?
N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide has a molecular weight of 4672.17 g/mol, XLogP of 56.16, 57 rotatable bonds, 19 hydrogen bond donors, and 48 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-bromo-1-cyclobutyl-4-(trifluoromethyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-(1-tert-butyl-6-isocyanobenzimidazol-2-yl)-4,4,4-trifluoro-3,3-dimethylbutanamide;N-[6-cyano-5-fluoro-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[6-cyano-1-(2,2,2-trifluoroethyl)benzimidazol-2-yl]-3-(2-fluorophenyl)-3-hydroxybutanamide;N-[1-cyclobutyl-6-(3,3-difluoroazetidin-1-yl)-7-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(1,3-difluoro-2-hydroxypropan-2-yl)-4-fluorobenzimidazol-2-yl]-3,3-dimethylbutanamide;N-[1-cyclobutyl-6-(dimethylamino)-7-fluorobenzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide;N-(1-cyclobutyl-4-fluoro-6-isocyanobenzimidazol-2-yl)-3-cyclopropyl-3-methylbutanamide;N-(1-cyclobutyl-7-methoxybenzimidazol-2-yl)-3,3-dimethylbutanamide;N-[7-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3,3-dimethylbutanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-3-(fluoromethyl)-3-methylpentanamide;N-[4-fluoro-6-(2-hydroxypropan-2-yl)-1-(1-methylcyclobutyl)benzimidazol-2-yl]-2-(1-methylcyclopropyl)acetamide is sourced from PubChem (CID 158349609), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).