N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide

C144H132N30O18S3 — CID 158358760

About N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide

N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide (PubChem CID 158358760) has the molecular formula C144H132N30O18S3 and a molecular weight of 2667.03 g/mol. Its IUPAC name is N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide.

Molecular Properties

• Compound Name: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide
• PubChem CID: 158358760
• Molecular Formula: C144H132N30O18S3
• Molecular Weight: 2667.03 g/mol
• Exact Mass: 2664.95
• IUPAC Name: N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide
• SMILES: Cc1cc(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NC2CC2)n(-c2cnccn2)n1.Cc1cc(C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)n(-c2ccc(-c3ccccc3)cc2)n1.Cc1cc(C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)n(-c2nc(-c3ccccc3)cs2)n1.Cc1cccc(-n2nc(C)cc2C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)n1.O=C(NC1CC1)C(=O)C(Cc1ccccc1)NC(=O)c1scnc1-n1cc(-c2ccccc2)cn1.O=C(NC1CC1)C(=O)C(Cc1ccccc1)NC(=O)c1scnc1-n1ncc2ccccc21
• InChI: InChI=1S/C27H24N4O3.C26H23N5O3S.2C24H21N5O3S.C22H22N6O3.C21H21N5O3/c1-18-16-24(27(34)29-23(25(32)26(28)33)17-19-8-4-2-5-9-19)31(30-18)22-14-12-21(13-15-22)20-10-6-3-7-11-20;32-22(25(33)29-20-11-12-20)21(13-17-7-3-1-4-8-17)30-26(34)23-24(27-16-35-23)31-15-19(14-28-31)18-9-5-2-6-10-18;30-20(23(31)27-17-10-11-17)18(12-15-6-2-1-3-7-15)28-24(32)21-22(25-14-33-21)29-19-9-5-4-8-16(19)13-26-29;1-15-12-20(29(28-15)24-27-19(14-33-24)17-10-6-3-7-11-17)23(32)26-18(21(30)22(25)31)13-16-8-4-2-5-9-16;1-14-11-18(28(27-14)19-13-23-9-10-24-19)21(30)26-17(12-15-5-3-2-4-6-15)20(29)22(31)25-16-7-8-16;1-13-7-6-10-18(23-13)26-17(11-14(2)25-26)21(29)24-16(19(27)20(22)28)12-15-8-4-3-5-9-15/h2-16,23H,17H2,1H3,(H2,28,33)(H,29,34);1-10,14-16,20-21H,11-13H2,(H,29,33)(H,30,34);1-9,13-14,17-18H,10-12H2,(H,27,31)(H,28,32);2-12,14,18H,13H2,1H3,(H2,25,31)(H,26,32);2-6,9-11,13,16-17H,7-8,12H2,1H3,(H,25,31)(H,26,30);3-11,16H,12H2,1-2H3,(H2,22,28)(H,24,29)
• InChIKey: GTFCCDRCNHEIOZ-UHFFFAOYSA-N
• XLogP: 14.24
• TPSA: 677.85 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 39
• Rotatable Bonds: 48
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2667.03
LogP ≤ 5	14.24
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	39

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'diketo_group', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide?

The IUPAC name of N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide (CID 158358760) is N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide.

What is the SMILES notation for N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide?

The canonical SMILES for N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide is Cc1cc(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NC2CC2)n(-c2cnccn2)n1.Cc1cc(C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)n(-c2ccc(-c3ccccc3)cc2)n1.Cc1cc(C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)n(-c2nc(-c3ccccc3)cs2)n1.Cc1cccc(-n2nc(C)cc2C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)n1.O=C(NC1CC1)C(=O)C(Cc1ccccc1)NC(=O)c1scnc1-n1cc(-c2ccccc2)cn1.O=C(NC1CC1)C(=O)C(Cc1ccccc1)NC(=O)c1scnc1-n1ncc2ccccc21.

What is the InChIKey of N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide?

The InChIKey is GTFCCDRCNHEIOZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H24N4O3.C26H23N5O3S.2C24H21N5O3S.C22H22N6O3.C21H21N5O3/c1-18-16-24(27(34)29-23(25(32)26(28)33)17-19-8-4-2-5-9-19)31(30-18)22-14-12-21(13-15-22)20-10-6-3-7-11-20;32-22(25(33)29-20-11-12-20)21(13-17-7-3-1-4-8-17)30-26(34)23-24(27-16-35-23)31-15-19(14-28-31)18-9-5-2-6-10-18;30-20(23(31)27-17-10-11-17)18(12-15-6-2-1-3-7-15)28-24(32)21-22(25-14-33-21)29-19-9-5-4-8-16(19)13-26-29;1-15-12-20(29(28-15)24-27-19(14-33-24)17-10-6-3-7-11-17)23(32)26-18(21(30)22(25)31)13-16-8-4-2-5-9-16;1-14-11-18(28(27-14)19-13-23-9-10-24-19)21(30)26-17(12-15-5-3-2-4-6-15)20(29)22(31)25-16-7-8-16;1-13-7-6-10-18(23-13)26-17(11-14(2)25-26)21(29)24-16(19(27)20(22)28)12-15-8-4-3-5-9-15/h2-16,23H,17H2,1H3,(H2,28,33)(H,29,34);1-10,14-16,20-21H,11-13H2,(H,29,33)(H,30,34);1-9,13-14,17-18H,10-12H2,(H,27,31)(H,28,32);2-12,14,18H,13H2,1H3,(H2,25,31)(H,26,32);2-6,9-11,13,16-17H,7-8,12H2,1H3,(H,25,31)(H,26,30);3-11,16H,12H2,1-2H3,(H2,22,28)(H,24,29).

What are the key properties of N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide?

N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide has a molecular weight of 2667.03 g/mol, XLogP of 14.24, 48 rotatable bonds, 12 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(6-methyl-2-pyridinyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenylphenyl)pyrazole-3-carboxamide;N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-indazol-1-yl-1,3-thiazole-5-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-5-methyl-2-pyrazin-2-ylpyrazole-3-carboxamide;N-[4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-yl]-4-(4-phenylpyrazol-1-yl)-1,3-thiazole-5-carboxamide is sourced from PubChem (CID 158358760), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).