4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide

C277H344N38O32 — CID 158362887

IUPAC4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide
SMILESCC(C)(C)C1=NN=C(Cc2cc(C(=O)NC[C@H](O)CN3CCc4ccccc4C3)ccn2)C1.CN(c1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1)C1CCC1.CN(c1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1)C1CCOCC1.COCCN1CCC(Oc2ccc(C(=O)NC[C@H](O)CN3CCc4ccccc4C3)cc2)CC1.COc1cc(C(=O)CC[C@H](O)CN2CCc3ccccc3C2)cc(NC2CCC2)n1.Cn1nccc1Cc1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1c(O)ccc2ccccc12.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc(OC2CCN(Cc3ccccc3)CC2)cc1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc(OC2CCN(Cc3ccncc3)CC2)cc1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc2c(c1O)CCCC2.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccnc(OC2CCOCC2)c1
InChIInChI=1S/C31H37N3O3.C30H36N4O3.C27H37N3O4.C26H33N5O2.C24H32N4O3.C24H31N3O3.C23H27N5O2.C23H30N4O2.C23H29N3O4.C23H24N2O3.C23H28N2O3/c35-28(23-34-17-14-25-8-4-5-9-27(25)22-34)20-32-31(36)26-10-12-29(13-11-26)37-30-15-18-33(19-16-30)21-24-6-2-1-3-7-24;35-27(22-34-16-11-24-3-1-2-4-26(24)21-34)19-32-30(36)25-5-7-28(8-6-25)37-29-12-17-33(18-13-29)20-23-9-14-31-15-10-23;1-33-17-16-29-14-11-26(12-15-29)34-25-8-6-22(7-9-25)27(32)28-18-24(31)20-30-13-10-21-4-2-3-5-23(21)19-30;1-26(2,3)24-14-22(29-30-24)13-21-12-19(8-10-27-21)25(33)28-15-23(32)17-31-11-9-18-6-4-5-7-20(18)16-31;1-27(21-8-12-31-13-9-21)23-14-19(6-10-25-23)24(30)26-15-22(29)17-28-11-7-18-4-2-3-5-20(18)16-28;1-30-24-14-19(13-23(26-24)25-20-7-4-8-20)22(29)10-9-21(28)16-27-12-11-17-5-2-3-6-18(17)15-27;1-27-21(7-10-26-27)13-20-12-18(6-9-24-20)23(30)25-14-22(29)16-28-11-8-17-4-2-3-5-19(17)15-28;1-26(20-7-4-8-20)22-13-18(9-11-24-22)23(29)25-14-21(28)16-27-12-10-17-5-2-3-6-19(17)15-27;27-20(16-26-10-6-17-3-1-2-4-19(17)15-26)14-25-23(28)18-5-9-24-22(13-18)30-21-7-11-29-12-8-21;26-19(15-25-12-11-16-5-1-2-7-18(16)14-25)13-24-23(28)22-20-8-4-3-6-17(20)9-10-21(22)27;26-19(15-25-12-11-16-5-1-2-7-18(16)14-25)13-24-23(28)21-10-9-17-6-3-4-8-20(17)22(21)27/h1-13,28,30,35H,14-23H2,(H,32,36);1-10,14-15,27,29,35H,11-13,16-22H2,(H,32,36);2-9,24,26,31H,10-20H2,1H3,(H,28,32);4-8,10,12,23,32H,9,11,13-17H2,1-3H3,(H,28,33);2-6,10,14,21-22,29H,7-9,11-13,15-17H2,1H3,(H,26,30);2-3,5-6,13-14,20-21,28H,4,7-12,15-16H2,1H3,(H,25,26);2-7,9-10,12,22,29H,8,11,13-16H2,1H3,(H,25,30);2-3,5-6,9,11,13,20-21,28H,4,7-8,10,12,14-16H2,1H3,(H,25,29);1-5,9,13,20-21,27H,6-8,10-12,14-16H2,(H,25,28);1-10,19,26-27H,11-15H2,(H,24,28);1-2,5,7,9-10,19,26-27H,3-4,6,8,11-15H2,(H,24,28)/t28-;27-;24-;23-;22-;21-;22-;21-;20-;2*19-/m00000000000/s1
InChIKeyGTRJJRDBYRTWGH-IIXZIYRKSA-N
MW4718.03 g/mol
LogP28.46
Rot. Bonds82

About 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide

4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide (PubChem CID 158362887) has the molecular formula C277H344N38O32 and a molecular weight of 4718.03 g/mol. Its IUPAC name is 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide.

Molecular Properties

Compound Name4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide
PubChem CID158362887
Molecular FormulaC277H344N38O32
Molecular Weight4718.03 g/mol
Exact Mass4714.65
IUPAC Name4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide
SMILESCC(C)(C)C1=NN=C(Cc2cc(C(=O)NC[C@H](O)CN3CCc4ccccc4C3)ccn2)C1.CN(c1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1)C1CCC1.CN(c1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1)C1CCOCC1.COCCN1CCC(Oc2ccc(C(=O)NC[C@H](O)CN3CCc4ccccc4C3)cc2)CC1.COc1cc(C(=O)CC[C@H](O)CN2CCc3ccccc3C2)cc(NC2CCC2)n1.Cn1nccc1Cc1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1c(O)ccc2ccccc12.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc(OC2CCN(Cc3ccccc3)CC2)cc1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc(OC2CCN(Cc3ccncc3)CC2)cc1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc2c(c1O)CCCC2.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccnc(OC2CCOCC2)c1
InChIInChI=1S/C31H37N3O3.C30H36N4O3.C27H37N3O4.C26H33N5O2.C24H32N4O3.C24H31N3O3.C23H27N5O2.C23H30N4O2.C23H29N3O4.C23H24N2O3.C23H28N2O3/c35-28(23-34-17-14-25-8-4-5-9-27(25)22-34)20-32-31(36)26-10-12-29(13-11-26)37-30-15-18-33(19-16-30)21-24-6-2-1-3-7-24;35-27(22-34-16-11-24-3-1-2-4-26(24)21-34)19-32-30(36)25-5-7-28(8-6-25)37-29-12-17-33(18-13-29)20-23-9-14-31-15-10-23;1-33-17-16-29-14-11-26(12-15-29)34-25-8-6-22(7-9-25)27(32)28-18-24(31)20-30-13-10-21-4-2-3-5-23(21)19-30;1-26(2,3)24-14-22(29-30-24)13-21-12-19(8-10-27-21)25(33)28-15-23(32)17-31-11-9-18-6-4-5-7-20(18)16-31;1-27(21-8-12-31-13-9-21)23-14-19(6-10-25-23)24(30)26-15-22(29)17-28-11-7-18-4-2-3-5-20(18)16-28;1-30-24-14-19(13-23(26-24)25-20-7-4-8-20)22(29)10-9-21(28)16-27-12-11-17-5-2-3-6-18(17)15-27;1-27-21(7-10-26-27)13-20-12-18(6-9-24-20)23(30)25-14-22(29)16-28-11-8-17-4-2-3-5-19(17)15-28;1-26(20-7-4-8-20)22-13-18(9-11-24-22)23(29)25-14-21(28)16-27-12-10-17-5-2-3-6-19(17)15-27;27-20(16-26-10-6-17-3-1-2-4-19(17)15-26)14-25-23(28)18-5-9-24-22(13-18)30-21-7-11-29-12-8-21;26-19(15-25-12-11-16-5-1-2-7-18(16)14-25)13-24-23(28)22-20-8-4-3-6-17(20)9-10-21(22)27;26-19(15-25-12-11-16-5-1-2-7-18(16)14-25)13-24-23(28)21-10-9-17-6-3-4-8-20(17)22(21)27/h1-13,28,30,35H,14-23H2,(H,32,36);1-10,14-15,27,29,35H,11-13,16-22H2,(H,32,36);2-9,24,26,31H,10-20H2,1H3,(H,28,32);4-8,10,12,23,32H,9,11,13-17H2,1-3H3,(H,28,33);2-6,10,14,21-22,29H,7-9,11-13,15-17H2,1H3,(H,26,30);2-3,5-6,13-14,20-21,28H,4,7-12,15-16H2,1H3,(H,25,26);2-7,9-10,12,22,29H,8,11,13-16H2,1H3,(H,25,30);2-3,5-6,9,11,13,20-21,28H,4,7-8,10,12,14-16H2,1H3,(H,25,29);1-5,9,13,20-21,27H,6-8,10-12,14-16H2,(H,25,28);1-10,19,26-27H,11-15H2,(H,24,28);1-2,5,7,9-10,19,26-27H,3-4,6,8,11-15H2,(H,24,28)/t28-;27-;24-;23-;22-;21-;22-;21-;20-;2*19-/m00000000000/s1
InChIKeyGTRJJRDBYRTWGH-IIXZIYRKSA-N
XLogP28.46
TPSA841.54 Ų
H-Bond Donors24
H-Bond Acceptors60
Rotatable Bonds82
Heavy Atoms347
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004718.03
LogP ≤ 528.46
H-Bond Donors ≤ 524
H-Bond Acceptors ≤ 1060

Analyze 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide?
The IUPAC name of 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide (CID 158362887) is 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide.
What is the SMILES notation for 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide?
The canonical SMILES for 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide is CC(C)(C)C1=NN=C(Cc2cc(C(=O)NC[C@H](O)CN3CCc4ccccc4C3)ccn2)C1.CN(c1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1)C1CCC1.CN(c1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1)C1CCOCC1.COCCN1CCC(Oc2ccc(C(=O)NC[C@H](O)CN3CCc4ccccc4C3)cc2)CC1.COc1cc(C(=O)CC[C@H](O)CN2CCc3ccccc3C2)cc(NC2CCC2)n1.Cn1nccc1Cc1cc(C(=O)NC[C@H](O)CN2CCc3ccccc3C2)ccn1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1c(O)ccc2ccccc12.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc(OC2CCN(Cc3ccccc3)CC2)cc1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc(OC2CCN(Cc3ccncc3)CC2)cc1.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccc2c(c1O)CCCC2.O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccnc(OC2CCOCC2)c1.
What is the InChIKey of 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide?
The InChIKey is GTRJJRDBYRTWGH-IIXZIYRKSA-N. The full InChI is InChI=1S/C31H37N3O3.C30H36N4O3.C27H37N3O4.C26H33N5O2.C24H32N4O3.C24H31N3O3.C23H27N5O2.C23H30N4O2.C23H29N3O4.C23H24N2O3.C23H28N2O3/c35-28(23-34-17-14-25-8-4-5-9-27(25)22-34)20-32-31(36)26-10-12-29(13-11-26)37-30-15-18-33(19-16-30)21-24-6-2-1-3-7-24;35-27(22-34-16-11-24-3-1-2-4-26(24)21-34)19-32-30(36)25-5-7-28(8-6-25)37-29-12-17-33(18-13-29)20-23-9-14-31-15-10-23;1-33-17-16-29-14-11-26(12-15-29)34-25-8-6-22(7-9-25)27(32)28-18-24(31)20-30-13-10-21-4-2-3-5-23(21)19-30;1-26(2,3)24-14-22(29-30-24)13-21-12-19(8-10-27-21)25(33)28-15-23(32)17-31-11-9-18-6-4-5-7-20(18)16-31;1-27(21-8-12-31-13-9-21)23-14-19(6-10-25-23)24(30)26-15-22(29)17-28-11-7-18-4-2-3-5-20(18)16-28;1-30-24-14-19(13-23(26-24)25-20-7-4-8-20)22(29)10-9-21(28)16-27-12-11-17-5-2-3-6-18(17)15-27;1-27-21(7-10-26-27)13-20-12-18(6-9-24-20)23(30)25-14-22(29)16-28-11-8-17-4-2-3-5-19(17)15-28;1-26(20-7-4-8-20)22-13-18(9-11-24-22)23(29)25-14-21(28)16-27-12-10-17-5-2-3-6-19(17)15-27;27-20(16-26-10-6-17-3-1-2-4-19(17)15-26)14-25-23(28)18-5-9-24-22(13-18)30-21-7-11-29-12-8-21;26-19(15-25-12-11-16-5-1-2-7-18(16)14-25)13-24-23(28)22-20-8-4-3-6-17(20)9-10-21(22)27;26-19(15-25-12-11-16-5-1-2-7-18(16)14-25)13-24-23(28)21-10-9-17-6-3-4-8-20(17)22(21)27/h1-13,28,30,35H,14-23H2,(H,32,36);1-10,14-15,27,29,35H,11-13,16-22H2,(H,32,36);2-9,24,26,31H,10-20H2,1H3,(H,28,32);4-8,10,12,23,32H,9,11,13-17H2,1-3H3,(H,28,33);2-6,10,14,21-22,29H,7-9,11-13,15-17H2,1H3,(H,26,30);2-3,5-6,13-14,20-21,28H,4,7-12,15-16H2,1H3,(H,25,26);2-7,9-10,12,22,29H,8,11,13-16H2,1H3,(H,25,30);2-3,5-6,9,11,13,20-21,28H,4,7-8,10,12,14-16H2,1H3,(H,25,29);1-5,9,13,20-21,27H,6-8,10-12,14-16H2,(H,25,28);1-10,19,26-27H,11-15H2,(H,24,28);1-2,5,7,9-10,19,26-27H,3-4,6,8,11-15H2,(H,24,28)/t28-;27-;24-;23-;22-;21-;22-;21-;20-;2*19-/m00000000000/s1.
What are the key properties of 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide?
4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide has a molecular weight of 4718.03 g/mol, XLogP of 28.46, 82 rotatable bonds, 24 hydrogen bond donors, and 60 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(1-benzylpiperidin-4-yl)oxy-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;2-[(5-tert-butyl-4H-pyrazol-3-yl)methyl]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;(4S)-1-[2-(cyclobutylamino)-6-methoxy-4-pyridinyl]-5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxypentan-1-one;2-[cyclobutyl(methyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-hydroxynaphthalene-1-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-1-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2-methoxyethyl)piperidin-4-yl]oxybenzamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[methyl(oxan-4-yl)amino]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-[(2-methylpyrazol-3-yl)methyl]pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-2-(oxan-4-yloxy)pyridine-4-carboxamide;N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(pyridin-4-ylmethyl)piperidin-4-yl]oxybenzamide is sourced from PubChem (CID 158362887), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).