4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol

C221H232Br2Cl9F3N16O9 — CID 158369911

IUPAC4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol
SMILESCC(c1ccccc1Cl)N1CCC2(CC1)C(=O)NCN2c1ccccc1.CCCCC(c1ccc(F)cc1)N1CCC2(CC1)C(=O)NCN2c1ccccc1.Cc1ccccc1C(c1ccccc1)N1CCC(O)(c2ccccc2)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2Br)c2ccccc2Br)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2F)c2ccccc2F)CC1.OC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl.OC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl.OC1(c2ccccc2)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1
InChIInChI=1S/2C26H25Cl2NO.C25H26Br2N2O.C25H26Cl2N2O.C25H26F2N2O.C25H27NO.C24H23Cl2NO.C24H30FN3O.C21H24ClN3O/c2*27-23-12-6-4-10-21(23)25(22-11-5-7-13-24(22)28)29-19-14-15-20(29)17-26(30,16-19)18-8-2-1-3-9-18;3*26-22-11-5-2-8-19(22)24(20-9-3-6-12-23(20)27)29-15-13-25(30,14-16-29)21-10-4-1-7-18(21)17-28;1-20-10-8-9-15-23(20)24(21-11-4-2-5-12-21)26-18-16-25(27,17-19-26)22-13-6-3-7-14-22;25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18;1-2-3-9-22(19-10-12-20(25)13-11-19)27-16-14-24(15-17-27)23(29)26-18-28(24)21-7-5-4-6-8-21;1-16(18-9-5-6-10-19(18)22)24-13-11-21(12-14-24)20(26)23-15-25(21)17-7-3-2-4-8-17/h2*1-13,19-20,25,30H,14-17H2;3*1-12,24,30H,13-17,28H2;2-15,24,27H,16-19H2,1H3;1-13,23,28H,14-17H2;4-8,10-13,22H,2-3,9,14-18H2,1H3,(H,26,29);2-10,16H,11-15H2,1H3,(H,23,26)
InChIKeyGUMDULCZXNQNLS-UHFFFAOYSA-N
MW3792.27 g/mol
LogP48.41
Rot. Bonds40

About 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol

4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol (PubChem CID 158369911) has the molecular formula C221H232Br2Cl9F3N16O9 and a molecular weight of 3792.27 g/mol. Its IUPAC name is 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol.

Molecular Properties

Compound Name4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol
PubChem CID158369911
Molecular FormulaC221H232Br2Cl9F3N16O9
Molecular Weight3792.27 g/mol
Exact Mass3783.37
IUPAC Name4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol
SMILESCC(c1ccccc1Cl)N1CCC2(CC1)C(=O)NCN2c1ccccc1.CCCCC(c1ccc(F)cc1)N1CCC2(CC1)C(=O)NCN2c1ccccc1.Cc1ccccc1C(c1ccccc1)N1CCC(O)(c2ccccc2)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2Br)c2ccccc2Br)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2F)c2ccccc2F)CC1.OC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl.OC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl.OC1(c2ccccc2)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1
InChIInChI=1S/2C26H25Cl2NO.C25H26Br2N2O.C25H26Cl2N2O.C25H26F2N2O.C25H27NO.C24H23Cl2NO.C24H30FN3O.C21H24ClN3O/c2*27-23-12-6-4-10-21(23)25(22-11-5-7-13-24(22)28)29-19-14-15-20(29)17-26(30,16-19)18-8-2-1-3-9-18;3*26-22-11-5-2-8-19(22)24(20-9-3-6-12-23(20)27)29-15-13-25(30,14-16-29)21-10-4-1-7-18(21)17-28;1-20-10-8-9-15-23(20)24(21-11-4-2-5-12-21)26-18-16-25(27,17-19-26)22-13-6-3-7-14-22;25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18;1-2-3-9-22(19-10-12-20(25)13-11-19)27-16-14-24(15-17-27)23(29)26-18-28(24)21-7-5-4-6-8-21;1-16(18-9-5-6-10-19(18)22)24-13-11-21(12-14-24)20(26)23-15-25(21)17-7-3-2-4-8-17/h2*1-13,19-20,25,30H,14-17H2;3*1-12,24,30H,13-17,28H2;2-15,24,27H,16-19H2,1H3;1-13,23,28H,14-17H2;4-8,10-13,22H,2-3,9,14-18H2,1H3,(H,26,29);2-10,16H,11-15H2,1H3,(H,23,26)
InChIKeyGUMDULCZXNQNLS-UHFFFAOYSA-N
XLogP48.41
TPSA313.51 Ų
H-Bond Donors12
H-Bond Acceptors23
Rotatable Bonds40
Heavy Atoms260
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003792.27
LogP ≤ 548.41
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1023

Analyze 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol with MolForge

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Frequently Asked Questions

What is the IUPAC name of 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol?
The IUPAC name of 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol (CID 158369911) is 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol.
What is the SMILES notation for 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol?
The canonical SMILES for 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol is CC(c1ccccc1Cl)N1CCC2(CC1)C(=O)NCN2c1ccccc1.CCCCC(c1ccc(F)cc1)N1CCC2(CC1)C(=O)NCN2c1ccccc1.Cc1ccccc1C(c1ccccc1)N1CCC(O)(c2ccccc2)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2Br)c2ccccc2Br)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1.NCc1ccccc1C1(O)CCN(C(c2ccccc2F)c2ccccc2F)CC1.OC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl.OC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl.OC1(c2ccccc2)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1.
What is the InChIKey of 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol?
The InChIKey is GUMDULCZXNQNLS-UHFFFAOYSA-N. The full InChI is InChI=1S/2C26H25Cl2NO.C25H26Br2N2O.C25H26Cl2N2O.C25H26F2N2O.C25H27NO.C24H23Cl2NO.C24H30FN3O.C21H24ClN3O/c2*27-23-12-6-4-10-21(23)25(22-11-5-7-13-24(22)28)29-19-14-15-20(29)17-26(30,16-19)18-8-2-1-3-9-18;3*26-22-11-5-2-8-19(22)24(20-9-3-6-12-23(20)27)29-15-13-25(30,14-16-29)21-10-4-1-7-18(21)17-28;1-20-10-8-9-15-23(20)24(21-11-4-2-5-12-21)26-18-16-25(27,17-19-26)22-13-6-3-7-14-22;25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18;1-2-3-9-22(19-10-12-20(25)13-11-19)27-16-14-24(15-17-27)23(29)26-18-28(24)21-7-5-4-6-8-21;1-16(18-9-5-6-10-19(18)22)24-13-11-21(12-14-24)20(26)23-15-25(21)17-7-3-2-4-8-17/h2*1-13,19-20,25,30H,14-17H2;3*1-12,24,30H,13-17,28H2;2-15,24,27H,16-19H2,1H3;1-13,23,28H,14-17H2;4-8,10-13,22H,2-3,9,14-18H2,1H3,(H,26,29);2-10,16H,11-15H2,1H3,(H,23,26).
What are the key properties of 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol?
4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol has a molecular weight of 3792.27 g/mol, XLogP of 48.41, 40 rotatable bonds, 12 hydrogen bond donors, and 23 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]piperidin-4-ol;4-[2-(aminomethyl)phenyl]-1-[bis(2-fluorophenyl)methyl]piperidin-4-ol;bis(8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol);1-[bis(2-chlorophenyl)methyl]-4-phenylpiperidin-4-ol;8-[1-(2-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[1-(4-fluorophenyl)pentyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;1-[(2-methylphenyl)-phenylmethyl]-4-phenylpiperidin-4-ol is sourced from PubChem (CID 158369911), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).