[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide

C74H81N23O4 — CID 158371737

IUPAC[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide
SMILESCN1CCN(C(=O)N2CCC(c3nc(-c4cc5ccccc5[nH]4)c4c(N)nccn34)CC2)CC1.Nc1nccn2c(C3CCN(C(=O)N4CCOCC4)CC3)nc(-c3cc4ccccc4[nH]3)c12.Nc1nccn2c(C3CCN(C(=O)Nc4cccnc4)CC3)nc(-c3cc4ccccc4[nH]3)c12
InChIInChI=1S/C25H30N8O.C25H24N8O.C24H27N7O2/c1-30-12-14-32(15-13-30)25(34)31-9-6-17(7-10-31)24-29-21(22-23(26)27-8-11-33(22)24)20-16-18-4-2-3-5-19(18)28-20;26-23-22-21(20-14-17-4-1-2-6-19(17)30-20)31-24(33(22)13-10-28-23)16-7-11-32(12-8-16)25(34)29-18-5-3-9-27-15-18;25-22-21-20(19-15-17-3-1-2-4-18(17)27-19)28-23(31(21)10-7-26-22)16-5-8-29(9-6-16)24(32)30-11-13-33-14-12-30/h2-5,8,11,16-17,28H,6-7,9-10,12-15H2,1H3,(H2,26,27);1-6,9-10,13-16,30H,7-8,11-12H2,(H2,26,28)(H,29,34);1-4,7,10,15-16,27H,5-6,8-9,11-14H2,(H2,25,26)
InChIKeyGURQZNLOOKCKKR-UHFFFAOYSA-N
MW1356.62 g/mol
LogP10.36
Rot. Bonds7

About [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide

[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide (PubChem CID 158371737) has the molecular formula C74H81N23O4 and a molecular weight of 1356.62 g/mol. Its IUPAC name is [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide.

Molecular Properties

Compound Name[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide
PubChem CID158371737
Molecular FormulaC74H81N23O4
Molecular Weight1356.62 g/mol
Exact Mass1355.68
IUPAC Name[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide
SMILESCN1CCN(C(=O)N2CCC(c3nc(-c4cc5ccccc5[nH]4)c4c(N)nccn34)CC2)CC1.Nc1nccn2c(C3CCN(C(=O)N4CCOCC4)CC3)nc(-c3cc4ccccc4[nH]3)c12.Nc1nccn2c(C3CCN(C(=O)Nc4cccnc4)CC3)nc(-c3cc4ccccc4[nH]3)c12
InChIInChI=1S/C25H30N8O.C25H24N8O.C24H27N7O2/c1-30-12-14-32(15-13-30)25(34)31-9-6-17(7-10-31)24-29-21(22-23(26)27-8-11-33(22)24)20-16-18-4-2-3-5-19(18)28-20;26-23-22-21(20-14-17-4-1-2-6-19(17)30-20)31-24(33(22)13-10-28-23)16-7-11-32(12-8-16)25(34)29-18-5-3-9-27-15-18;25-22-21-20(19-15-17-3-1-2-4-18(17)27-19)28-23(31(21)10-7-26-22)16-5-8-29(9-6-16)24(32)30-11-13-33-14-12-30/h2-5,8,11,16-17,28H,6-7,9-10,12-15H2,1H3,(H2,26,27);1-6,9-10,13-16,30H,7-8,11-12H2,(H2,26,28)(H,29,34);1-4,7,10,15-16,27H,5-6,8-9,11-14H2,(H2,25,26)
InChIKeyGURQZNLOOKCKKR-UHFFFAOYSA-N
XLogP10.36
TPSA320.80 Ų
H-Bond Donors7
H-Bond Acceptors18
Rotatable Bonds7
Heavy Atoms101
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001356.62
LogP ≤ 510.36
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1018

Analyze [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-(8-Amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl)-N,N-dimethylpiperidine-1-carboxamide
CID 16679060
[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone
CID 54587314
4-[5-(1H-imidazo[4,5-b]pyridin-6-yl)-2-[(E)-2-quinolin-2-ylethenyl]imidazo[1,2-a]pyrazin-8-yl]morpholine
CID 86345985
(E)-6-(8-Morpholino-2-(2-(quinolin-2-yl)vinyl)imidazo[1,2-a]pyrazin-5-yl)-3H-imidazo[4,5-b]pyridin-2-ol
CID 136310639
6-[8-Morpholin-4-yl-2-(2-quinolin-2-ylethyl)imidazo[1,2-a]pyrazin-5-yl]-1,3-dihydroimidazo[4,5-b]pyridin-2-one
CID 137083638
4-[4-[4-[4-(4-methyl-5-phenyl-1H-imidazol-2-yl)-1-piperidyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-pyridyl]morpholine
CID 118414232
9H-Pyrimido(4,5-b)indole, 9-(2-(4-morpholinyl)ethyl)-2,4-di-1-pyrrolidinyl-, hydrochloride, hydrate (2:2:1)
CID 129649853
3-[1-[[9-ethyl-2-(5-fluoro-1H-indol-4-yl)-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]-1,3-oxazolidin-2-one
CID 25264664
(3r,4s)-1-((2-(1h-Indol-3-yl)-9-methyl-6-morpholino-9h-purin-8-yl)methyl)-3-fluoro-n,n-dimethylpiperidin-4-amine
CID 59603444
(3S,4R)-3-fluoro-1-[[2-(1H-indol-3-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]-N,N-dimethylpiperidin-4-amine
CID 59603475
1-((2-(1h-Indol-3-yl)-9-methyl-6-morpholino-9h-purin-8-yl)methyl)-3-fluoro-n,n-dimethylpiperidin-4-amine
CID 67279564
5-[2,6-bis[(3S)-3-methylmorpholin-4-yl]-7H-purin-8-yl]-1,3-dihydrobenzimidazol-2-one;(3S)-4-[2-(4,4-difluoropiperidin-1-yl)-8-(1H-indol-4-yl)-7H-purin-6-yl]-3-methylmorpholine
CID 88925583

Frequently Asked Questions

What is the IUPAC name of [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide?
The IUPAC name of [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide (CID 158371737) is [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide.
What is the SMILES notation for [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide?
The canonical SMILES for [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide is CN1CCN(C(=O)N2CCC(c3nc(-c4cc5ccccc5[nH]4)c4c(N)nccn34)CC2)CC1.Nc1nccn2c(C3CCN(C(=O)N4CCOCC4)CC3)nc(-c3cc4ccccc4[nH]3)c12.Nc1nccn2c(C3CCN(C(=O)Nc4cccnc4)CC3)nc(-c3cc4ccccc4[nH]3)c12.
What is the InChIKey of [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide?
The InChIKey is GURQZNLOOKCKKR-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H30N8O.C25H24N8O.C24H27N7O2/c1-30-12-14-32(15-13-30)25(34)31-9-6-17(7-10-31)24-29-21(22-23(26)27-8-11-33(22)24)20-16-18-4-2-3-5-19(18)28-20;26-23-22-21(20-14-17-4-1-2-6-19(17)30-20)31-24(33(22)13-10-28-23)16-7-11-32(12-8-16)25(34)29-18-5-3-9-27-15-18;25-22-21-20(19-15-17-3-1-2-4-18(17)27-19)28-23(31(21)10-7-26-22)16-5-8-29(9-6-16)24(32)30-11-13-33-14-12-30/h2-5,8,11,16-17,28H,6-7,9-10,12-15H2,1H3,(H2,26,27);1-6,9-10,13-16,30H,7-8,11-12H2,(H2,26,28)(H,29,34);1-4,7,10,15-16,27H,5-6,8-9,11-14H2,(H2,25,26).
What are the key properties of [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide?
[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide has a molecular weight of 1356.62 g/mol, XLogP of 10.36, 7 rotatable bonds, 7 hydrogen bond donors, and 18 hydrogen bond acceptors.
Where does this data come from?
All data for [4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-(4-methylpiperazin-1-yl)methanone;[4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-morpholin-4-ylmethanone;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-3-ylpiperidine-1-carboxamide is sourced from PubChem (CID 158371737), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).