4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine

C95H92F5N29O4 — CID 158374059

IUPAC4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine
SMILESCNc1c(F)ccc2c1[nH]c1nc(Oc3ccc(C)nc3)nc(N3CC[C@@H](N)C3)c12.CNc1c(F)ccc2c1[nH]c1nc(Oc3cccnc3)nc(N3CC4C(N)C4C3)c12.CNc1c(F)ccc2c1[nH]c1nc(Oc3cnc4ccccc4c3)nc(N3C[C@@H](N)C4(CC4)C3)c12.CNc1cc(F)c(F)c2c1[nH]c1nc(Oc3cnc4c(c3)ncn4C3CC3)nc(N3C[C@H]4C[C@@H]3C[C@H]4C)c12
InChIInChI=1S/C27H26F2N8O.C26H24FN7O.C21H20FN7O.C21H22FN7O/c1-12-5-15-6-13(12)10-36(15)26-21-20-22(29)17(28)8-18(30-2)23(20)33-24(21)34-27(35-26)38-16-7-19-25(31-9-16)37(11-32-19)14-3-4-14;1-29-22-17(27)7-6-16-20-23(31-21(16)22)32-25(33-24(20)34-12-19(28)26(13-34)8-9-26)35-15-10-14-4-2-3-5-18(14)30-11-15;1-24-18-14(22)5-4-11-15-19(26-17(11)18)27-21(30-10-3-2-6-25-7-10)28-20(15)29-8-12-13(9-29)16(12)23;1-11-3-4-13(9-25-11)30-21-27-19-16(20(28-21)29-8-7-12(23)10-29)14-5-6-15(22)18(24-2)17(14)26-19/h7-9,11-15,30H,3-6,10H2,1-2H3,(H,33,34,35);2-7,10-11,19,29H,8-9,12-13,28H2,1H3,(H,31,32,33);2-7,12-13,16,24H,8-9,23H2,1H3,(H,26,27,28);3-6,9,12,24H,7-8,10,23H2,1-2H3,(H,26,27,28)/t12-,13-,15+;19-;;12-/m11.1/s1
InChIKeyGUZAZNBCCPORIQ-YSECJALBSA-N
MW1798.97 g/mol
LogP16.30
Rot. Bonds17

About 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine

4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine (PubChem CID 158374059) has the molecular formula C95H92F5N29O4 and a molecular weight of 1798.97 g/mol. Its IUPAC name is 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine.

Molecular Properties

Compound Name4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine
PubChem CID158374059
Molecular FormulaC95H92F5N29O4
Molecular Weight1798.97 g/mol
Exact Mass1797.78
IUPAC Name4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine
SMILESCNc1c(F)ccc2c1[nH]c1nc(Oc3ccc(C)nc3)nc(N3CC[C@@H](N)C3)c12.CNc1c(F)ccc2c1[nH]c1nc(Oc3cccnc3)nc(N3CC4C(N)C4C3)c12.CNc1c(F)ccc2c1[nH]c1nc(Oc3cnc4ccccc4c3)nc(N3C[C@@H](N)C4(CC4)C3)c12.CNc1cc(F)c(F)c2c1[nH]c1nc(Oc3cnc4c(c3)ncn4C3CC3)nc(N3C[C@H]4C[C@@H]3C[C@H]4C)c12
InChIInChI=1S/C27H26F2N8O.C26H24FN7O.C21H20FN7O.C21H22FN7O/c1-12-5-15-6-13(12)10-36(15)26-21-20-22(29)17(28)8-18(30-2)23(20)33-24(21)34-27(35-26)38-16-7-19-25(31-9-16)37(11-32-19)14-3-4-14;1-29-22-17(27)7-6-16-20-23(31-21(16)22)32-25(33-24(20)34-12-19(28)26(13-34)8-9-26)35-15-10-14-4-2-3-5-18(14)30-11-15;1-24-18-14(22)5-4-11-15-19(26-17(11)18)27-21(30-10-3-2-6-25-7-10)28-20(15)29-8-12-13(9-29)16(12)23;1-11-3-4-13(9-25-11)30-21-27-19-16(20(28-21)29-8-7-12(23)10-29)14-5-6-15(22)18(24-2)17(14)26-19/h7-9,11-15,30H,3-6,10H2,1-2H3,(H,33,34,35);2-7,10-11,19,29H,8-9,12-13,28H2,1H3,(H,31,32,33);2-7,12-13,16,24H,8-9,23H2,1H3,(H,26,27,28);3-6,9,12,24H,7-8,10,23H2,1-2H3,(H,26,27,28)/t12-,13-,15+;19-;;12-/m11.1/s1
InChIKeyGUZAZNBCCPORIQ-YSECJALBSA-N
XLogP16.30
TPSA411.72 Ų
H-Bond Donors11
H-Bond Acceptors29
Rotatable Bonds17
Heavy Atoms133
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001798.97
LogP ≤ 516.30
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1029

Analyze 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine with MolForge

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Launch Full Analysis

Related Compounds

4-(2-amino-5-azaspiro[2.3]hexan-5-yl)-6-fluoro-N-methyl-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-amine
CID 66549475
4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-amine
CID 66551096
4-[(1S,5R,6R)-6-amino-3-azabicyclo[3.2.0]heptan-3-yl]-6-fluoro-N-methyl-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-amine
CID 68271801
tert-butyl N-[6-fluoro-4-[(1R,5S)-6-methyl-3-azabicyclo[3.1.0]hexan-3-yl]-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-yl]-N-methylcarbamate
CID 68271803
6-fluoro-N-methyl-4-[(1R,5S)-6-methyl-3-azabicyclo[3.1.0]hexan-3-yl]-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-amine
CID 68271805
4-[(1R,4R,5R)-5-amino-2-azabicyclo[2.2.1]heptan-2-yl]-2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-9H-pyrimido[4,5-b]indol-8-amine
CID 68272370
4-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-6-fluoro-N-methyl-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-amine
CID 68308894
tert-butyl N-[(1S,5R)-3-[6-fluoro-8-(methylamino)-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-4-yl]-3-azabicyclo[3.1.0]hexan-6-yl]carbamate
CID 68309272
tert-butyl N-[6-fluoro-4-[(1R,5S)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-3-azabicyclo[3.1.0]hexan-3-yl]-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-yl]-N-methylcarbamate
CID 68310957
4-(6-amino-3-azabicyclo[3.2.0]heptan-3-yl)-6-fluoro-N-methyl-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-amine
CID 77447553
4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-6-fluoro-N-methyl-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-amine
CID 77474457
tert-butyl N-[6-fluoro-4-[6-[(2-methylpropan-2-yl)oxycarbonylamino]-3-azabicyclo[3.1.0]hexan-3-yl]-2-(1,5-naphthyridin-3-yloxy)-9H-pyrimido[4,5-b]indol-8-yl]-N-methylcarbamate
CID 77475188

Frequently Asked Questions

What is the IUPAC name of 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine?
The IUPAC name of 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine (CID 158374059) is 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine.
What is the SMILES notation for 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine?
The canonical SMILES for 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine is CNc1c(F)ccc2c1[nH]c1nc(Oc3ccc(C)nc3)nc(N3CC[C@@H](N)C3)c12.CNc1c(F)ccc2c1[nH]c1nc(Oc3cccnc3)nc(N3CC4C(N)C4C3)c12.CNc1c(F)ccc2c1[nH]c1nc(Oc3cnc4ccccc4c3)nc(N3C[C@@H](N)C4(CC4)C3)c12.CNc1cc(F)c(F)c2c1[nH]c1nc(Oc3cnc4c(c3)ncn4C3CC3)nc(N3C[C@H]4C[C@@H]3C[C@H]4C)c12.
What is the InChIKey of 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine?
The InChIKey is GUZAZNBCCPORIQ-YSECJALBSA-N. The full InChI is InChI=1S/C27H26F2N8O.C26H24FN7O.C21H20FN7O.C21H22FN7O/c1-12-5-15-6-13(12)10-36(15)26-21-20-22(29)17(28)8-18(30-2)23(20)33-24(21)34-27(35-26)38-16-7-19-25(31-9-16)37(11-32-19)14-3-4-14;1-29-22-17(27)7-6-16-20-23(31-21(16)22)32-25(33-24(20)34-12-19(28)26(13-34)8-9-26)35-15-10-14-4-2-3-5-18(14)30-11-15;1-24-18-14(22)5-4-11-15-19(26-17(11)18)27-21(30-10-3-2-6-25-7-10)28-20(15)29-8-12-13(9-29)16(12)23;1-11-3-4-13(9-25-11)30-21-27-19-16(20(28-21)29-8-7-12(23)10-29)14-5-6-15(22)18(24-2)17(14)26-19/h7-9,11-15,30H,3-6,10H2,1-2H3,(H,33,34,35);2-7,10-11,19,29H,8-9,12-13,28H2,1H3,(H,31,32,33);2-7,12-13,16,24H,8-9,23H2,1H3,(H,26,27,28);3-6,9,12,24H,7-8,10,23H2,1-2H3,(H,26,27,28)/t12-,13-,15+;19-;;12-/m11.1/s1.
What are the key properties of 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine?
4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine has a molecular weight of 1798.97 g/mol, XLogP of 16.30, 17 rotatable bonds, 11 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-7-fluoro-N-methyl-2-pyridin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-7-fluoro-N-methyl-2-quinolin-3-yloxy-9H-pyrimido[4,5-b]indol-8-amine;4-[(3R)-3-aminopyrrolidin-1-yl]-7-fluoro-N-methyl-2-[(6-methyl-3-pyridinyl)oxy]-9H-pyrimido[4,5-b]indol-8-amine;2-(3-cyclopropylimidazo[4,5-b]pyridin-6-yl)oxy-5,6-difluoro-N-methyl-4-[(1S,4S,5R)-5-methyl-2-azabicyclo[2.2.1]heptan-2-yl]-9H-pyrimido[4,5-b]indol-8-amine is sourced from PubChem (CID 158374059), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).