5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine

C364H327F14N87O3S18 — CID 158376862

IUPAC5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine
SMILESCN1CCN(c2ccc3nc(-c4ccc(N5CCCC5)nc4)sc3c2)C(=O)C1.Cc1c[nH]c(C)c1-c1ccc2sc(-c3ccc(N4CCCC4)nc3F)nc2n1.Cc1ccc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3n2)cn1.Cn1cc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3c2)cn1.Cn1ccc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4F)nc3n2)c1.Cn1ccc(-c2ccc3sc(-c4ccc(N5CCC[C@H](F)C5)nc4)nc3n2)c1.Cn1cccc1-c1ccc2sc(-c3ccc(N4CCCC4)nc3F)nc2n1.F[C@@H]1CCN(c2ccc(-c3nc4nc(-c5cccnc5)ccc4s3)cn2)C1.F[C@H]1CCCN(c2ccc(-c3nc4nc(-c5cc[nH]c5)ccc4s3)cn2)C1.F[C@H]1CCN(c2ccc(-c3nc4nc(-c5cccnc5)ccc4s3)cn2)C1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3cc[nH]c3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3cc[nH]c3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3ccc[nH]3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3ccccc3)ccc2s1.Fc1ncccc1-c1ccc2sc(-c3ccc(N4CCCC4)nc3)nc2n1.O=C1CCCCN1c1ccc2nc(-c3ccc(N4CC[C@@H](F)C4)nc3)sc2c1.O=C1CCCCN1c1ccc2nc(-c3ccc(N4CC[C@H](F)C4)nc3)sc2c1.c1cncc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3n2)c1
InChIInChI=1S/2C21H20FN5S.2C21H21FN4OS.C21H17FN4S.C21H23N5OS.C21H19N5S.3C20H18FN5S.3C20H16FN5S.C20H19N5S.C20H17N5S.3C19H16FN5S/c1-12-11-23-13(2)18(12)15-6-7-16-20(24-15)26-21(28-16)14-5-8-17(25-19(14)22)27-9-3-4-10-27;1-26-10-8-15(12-26)17-5-6-18-20(24-17)25-21(28-18)14-4-7-19(23-11-14)27-9-2-3-16(22)13-27;2*22-15-8-10-25(13-15)19-7-4-14(12-23-19)21-24-17-6-5-16(11-18(17)28-21)26-9-2-1-3-20(26)27;22-19-15(8-11-18(24-19)26-12-4-5-13-26)21-25-20-17(27-21)10-9-16(23-20)14-6-2-1-3-7-14;1-24-10-11-26(20(27)14-24)16-5-6-17-18(12-16)28-21(23-17)15-4-7-19(22-13-15)25-8-2-3-9-25;1-14-4-5-15(12-22-14)17-7-8-18-20(24-17)25-21(27-18)16-6-9-19(23-13-16)26-10-2-3-11-26;1-25-11-8-13(12-25)15-5-6-16-19(22-15)24-20(27-16)14-4-7-17(23-18(14)21)26-9-2-3-10-26;1-25-10-4-5-15(25)14-7-8-16-19(22-14)24-20(27-16)13-6-9-17(23-18(13)21)26-11-2-3-12-26;21-15-2-1-9-26(12-15)18-6-3-14(11-23-18)20-25-19-17(27-20)5-4-16(24-19)13-7-8-22-10-13;2*21-15-7-9-26(12-15)18-6-3-14(11-23-18)20-25-19-17(27-20)5-4-16(24-19)13-2-1-8-22-10-13;21-18-14(4-3-9-22-18)15-6-7-16-19(24-15)25-20(27-16)13-5-8-17(23-12-13)26-10-1-2-11-26;1-24-13-16(12-22-24)14-4-6-18-17(10-14)23-20(26-18)15-5-7-19(21-11-15)25-8-2-3-9-25;1-2-11-25(10-1)18-8-5-15(13-22-18)20-24-19-17(26-20)7-6-16(23-19)14-4-3-9-21-12-14;2*20-17-13(3-6-16(23-17)25-9-1-2-10-25)19-24-18-15(26-19)5-4-14(22-18)12-7-8-21-11-12;20-17-12(5-8-16(23-17)25-10-1-2-11-25)19-24-18-15(26-19)7-6-14(22-18)13-4-3-9-21-13/h5-8,11,23H,3-4,9-10H2,1-2H3;4-8,10-12,16H,2-3,9,13H2,1H3;2*4-7,11-12,15H,1-3,8-10,13H2;1-3,6-11H,4-5,12-13H2;4-7,12-13H,2-3,8-11,14H2,1H3;4-9,12-13H,2-3,10-11H2,1H3;4-8,11-12H,2-3,9-10H2,1H3;4-10H,2-3,11-12H2,1H3;3-8,10-11,15,22H,1-2,9,12H2;2*1-6,8,10-11,15H,7,9,12H2;3-9,12H,1-2,10-11H2;4-7,10-13H,2-3,8-9H2,1H3;3-9,12-13H,1-2,10-11H2;2*3-8,11,21H,1-2,9-10H2;3-9,21H,1-2,10-11H2/t;16-;2*15-;;;;;;3*15-;;;;;;/m.010.....010....../s1
InChIKeyGVHQVKMBRVVLRF-AWJLFLEDSA-N
MW6811.40 g/mol
LogP80.97
Rot. Bonds54

About 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine

5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine (PubChem CID 158376862) has the molecular formula C364H327F14N87O3S18 and a molecular weight of 6811.40 g/mol. Its IUPAC name is 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine.

Molecular Properties

Compound Name5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine
PubChem CID158376862
Molecular FormulaC364H327F14N87O3S18
Molecular Weight6811.40 g/mol
Exact Mass6805.29
IUPAC Name5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine
SMILESCN1CCN(c2ccc3nc(-c4ccc(N5CCCC5)nc4)sc3c2)C(=O)C1.Cc1c[nH]c(C)c1-c1ccc2sc(-c3ccc(N4CCCC4)nc3F)nc2n1.Cc1ccc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3n2)cn1.Cn1cc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3c2)cn1.Cn1ccc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4F)nc3n2)c1.Cn1ccc(-c2ccc3sc(-c4ccc(N5CCC[C@H](F)C5)nc4)nc3n2)c1.Cn1cccc1-c1ccc2sc(-c3ccc(N4CCCC4)nc3F)nc2n1.F[C@@H]1CCN(c2ccc(-c3nc4nc(-c5cccnc5)ccc4s3)cn2)C1.F[C@H]1CCCN(c2ccc(-c3nc4nc(-c5cc[nH]c5)ccc4s3)cn2)C1.F[C@H]1CCN(c2ccc(-c3nc4nc(-c5cccnc5)ccc4s3)cn2)C1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3cc[nH]c3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3cc[nH]c3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3ccc[nH]3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3ccccc3)ccc2s1.Fc1ncccc1-c1ccc2sc(-c3ccc(N4CCCC4)nc3)nc2n1.O=C1CCCCN1c1ccc2nc(-c3ccc(N4CC[C@@H](F)C4)nc3)sc2c1.O=C1CCCCN1c1ccc2nc(-c3ccc(N4CC[C@H](F)C4)nc3)sc2c1.c1cncc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3n2)c1
InChIInChI=1S/2C21H20FN5S.2C21H21FN4OS.C21H17FN4S.C21H23N5OS.C21H19N5S.3C20H18FN5S.3C20H16FN5S.C20H19N5S.C20H17N5S.3C19H16FN5S/c1-12-11-23-13(2)18(12)15-6-7-16-20(24-15)26-21(28-16)14-5-8-17(25-19(14)22)27-9-3-4-10-27;1-26-10-8-15(12-26)17-5-6-18-20(24-17)25-21(28-18)14-4-7-19(23-11-14)27-9-2-3-16(22)13-27;2*22-15-8-10-25(13-15)19-7-4-14(12-23-19)21-24-17-6-5-16(11-18(17)28-21)26-9-2-1-3-20(26)27;22-19-15(8-11-18(24-19)26-12-4-5-13-26)21-25-20-17(27-21)10-9-16(23-20)14-6-2-1-3-7-14;1-24-10-11-26(20(27)14-24)16-5-6-17-18(12-16)28-21(23-17)15-4-7-19(22-13-15)25-8-2-3-9-25;1-14-4-5-15(12-22-14)17-7-8-18-20(24-17)25-21(27-18)16-6-9-19(23-13-16)26-10-2-3-11-26;1-25-11-8-13(12-25)15-5-6-16-19(22-15)24-20(27-16)14-4-7-17(23-18(14)21)26-9-2-3-10-26;1-25-10-4-5-15(25)14-7-8-16-19(22-14)24-20(27-16)13-6-9-17(23-18(13)21)26-11-2-3-12-26;21-15-2-1-9-26(12-15)18-6-3-14(11-23-18)20-25-19-17(27-20)5-4-16(24-19)13-7-8-22-10-13;2*21-15-7-9-26(12-15)18-6-3-14(11-23-18)20-25-19-17(27-20)5-4-16(24-19)13-2-1-8-22-10-13;21-18-14(4-3-9-22-18)15-6-7-16-19(24-15)25-20(27-16)13-5-8-17(23-12-13)26-10-1-2-11-26;1-24-13-16(12-22-24)14-4-6-18-17(10-14)23-20(26-18)15-5-7-19(21-11-15)25-8-2-3-9-25;1-2-11-25(10-1)18-8-5-15(13-22-18)20-24-19-17(26-20)7-6-16(23-19)14-4-3-9-21-12-14;2*20-17-13(3-6-16(23-17)25-9-1-2-10-25)19-24-18-15(26-19)5-4-14(22-18)12-7-8-21-11-12;20-17-12(5-8-16(23-17)25-10-1-2-11-25)19-24-18-15(26-19)7-6-14(22-18)13-4-3-9-21-13/h5-8,11,23H,3-4,9-10H2,1-2H3;4-8,10-12,16H,2-3,9,13H2,1H3;2*4-7,11-12,15H,1-3,8-10,13H2;1-3,6-11H,4-5,12-13H2;4-7,12-13H,2-3,8-11,14H2,1H3;4-9,12-13H,2-3,10-11H2,1H3;4-8,11-12H,2-3,9-10H2,1H3;4-10H,2-3,11-12H2,1H3;3-8,10-11,15,22H,1-2,9,12H2;2*1-6,8,10-11,15H,7,9,12H2;3-9,12H,1-2,10-11H2;4-7,10-13H,2-3,8-9H2,1H3;3-9,12-13H,1-2,10-11H2;2*3-8,11,21H,1-2,9-10H2;3-9,21H,1-2,10-11H2/t;16-;2*15-;;;;;;3*15-;;;;;;/m.010.....010....../s1
InChIKeyGVHQVKMBRVVLRF-AWJLFLEDSA-N
XLogP80.97
TPSA943.00 Ų
H-Bond Donors5
H-Bond Acceptors100
Rotatable Bonds54
Heavy Atoms486
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5006811.40
LogP ≤ 580.97
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 10100

Analyze 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine with MolForge

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Frequently Asked Questions

What is the IUPAC name of 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine?
The IUPAC name of 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine (CID 158376862) is 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine.
What is the SMILES notation for 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine?
The canonical SMILES for 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine is CN1CCN(c2ccc3nc(-c4ccc(N5CCCC5)nc4)sc3c2)C(=O)C1.Cc1c[nH]c(C)c1-c1ccc2sc(-c3ccc(N4CCCC4)nc3F)nc2n1.Cc1ccc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3n2)cn1.Cn1cc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3c2)cn1.Cn1ccc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4F)nc3n2)c1.Cn1ccc(-c2ccc3sc(-c4ccc(N5CCC[C@H](F)C5)nc4)nc3n2)c1.Cn1cccc1-c1ccc2sc(-c3ccc(N4CCCC4)nc3F)nc2n1.F[C@@H]1CCN(c2ccc(-c3nc4nc(-c5cccnc5)ccc4s3)cn2)C1.F[C@H]1CCCN(c2ccc(-c3nc4nc(-c5cc[nH]c5)ccc4s3)cn2)C1.F[C@H]1CCN(c2ccc(-c3nc4nc(-c5cccnc5)ccc4s3)cn2)C1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3cc[nH]c3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3cc[nH]c3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3ccc[nH]3)ccc2s1.Fc1nc(N2CCCC2)ccc1-c1nc2nc(-c3ccccc3)ccc2s1.Fc1ncccc1-c1ccc2sc(-c3ccc(N4CCCC4)nc3)nc2n1.O=C1CCCCN1c1ccc2nc(-c3ccc(N4CC[C@@H](F)C4)nc3)sc2c1.O=C1CCCCN1c1ccc2nc(-c3ccc(N4CC[C@H](F)C4)nc3)sc2c1.c1cncc(-c2ccc3sc(-c4ccc(N5CCCC5)nc4)nc3n2)c1.
What is the InChIKey of 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine?
The InChIKey is GVHQVKMBRVVLRF-AWJLFLEDSA-N. The full InChI is InChI=1S/2C21H20FN5S.2C21H21FN4OS.C21H17FN4S.C21H23N5OS.C21H19N5S.3C20H18FN5S.3C20H16FN5S.C20H19N5S.C20H17N5S.3C19H16FN5S/c1-12-11-23-13(2)18(12)15-6-7-16-20(24-15)26-21(28-16)14-5-8-17(25-19(14)22)27-9-3-4-10-27;1-26-10-8-15(12-26)17-5-6-18-20(24-17)25-21(28-18)14-4-7-19(23-11-14)27-9-2-3-16(22)13-27;2*22-15-8-10-25(13-15)19-7-4-14(12-23-19)21-24-17-6-5-16(11-18(17)28-21)26-9-2-1-3-20(26)27;22-19-15(8-11-18(24-19)26-12-4-5-13-26)21-25-20-17(27-21)10-9-16(23-20)14-6-2-1-3-7-14;1-24-10-11-26(20(27)14-24)16-5-6-17-18(12-16)28-21(23-17)15-4-7-19(22-13-15)25-8-2-3-9-25;1-14-4-5-15(12-22-14)17-7-8-18-20(24-17)25-21(27-18)16-6-9-19(23-13-16)26-10-2-3-11-26;1-25-11-8-13(12-25)15-5-6-16-19(22-15)24-20(27-16)14-4-7-17(23-18(14)21)26-9-2-3-10-26;1-25-10-4-5-15(25)14-7-8-16-19(22-14)24-20(27-16)13-6-9-17(23-18(13)21)26-11-2-3-12-26;21-15-2-1-9-26(12-15)18-6-3-14(11-23-18)20-25-19-17(27-20)5-4-16(24-19)13-7-8-22-10-13;2*21-15-7-9-26(12-15)18-6-3-14(11-23-18)20-25-19-17(27-20)5-4-16(24-19)13-2-1-8-22-10-13;21-18-14(4-3-9-22-18)15-6-7-16-19(24-15)25-20(27-16)13-5-8-17(23-12-13)26-10-1-2-11-26;1-24-13-16(12-22-24)14-4-6-18-17(10-14)23-20(26-18)15-5-7-19(21-11-15)25-8-2-3-9-25;1-2-11-25(10-1)18-8-5-15(13-22-18)20-24-19-17(26-20)7-6-16(23-19)14-4-3-9-21-12-14;2*20-17-13(3-6-16(23-17)25-9-1-2-10-25)19-24-18-15(26-19)5-4-14(22-18)12-7-8-21-11-12;20-17-12(5-8-16(23-17)25-10-1-2-11-25)19-24-18-15(26-19)7-6-14(22-18)13-4-3-9-21-13/h5-8,11,23H,3-4,9-10H2,1-2H3;4-8,10-12,16H,2-3,9,13H2,1H3;2*4-7,11-12,15H,1-3,8-10,13H2;1-3,6-11H,4-5,12-13H2;4-7,12-13H,2-3,8-11,14H2,1H3;4-9,12-13H,2-3,10-11H2,1H3;4-8,11-12H,2-3,9-10H2,1H3;4-10H,2-3,11-12H2,1H3;3-8,10-11,15,22H,1-2,9,12H2;2*1-6,8,10-11,15H,7,9,12H2;3-9,12H,1-2,10-11H2;4-7,10-13H,2-3,8-9H2,1H3;3-9,12-13H,1-2,10-11H2;2*3-8,11,21H,1-2,9-10H2;3-9,21H,1-2,10-11H2/t;16-;2*15-;;;;;;3*15-;;;;;;/m.010.....010....../s1.
What are the key properties of 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine?
5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine has a molecular weight of 6811.40 g/mol, XLogP of 80.97, 54 rotatable bonds, 5 hydrogen bond donors, and 100 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(2,4-dimethyl-1H-pyrrol-3-yl)-2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropiperidin-1-yl]-3-pyridinyl]-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;5-(2-fluoro-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;1-[2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;1-[2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-1,3-benzothiazol-6-yl]piperidin-2-one;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1-methylpyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-phenyl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3R)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-[6-[(3S)-3-fluoropyrrolidin-1-yl]-3-pyridinyl]-5-pyridin-3-yl-[1,3]thiazolo[4,5-b]pyridine;2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-2-yl)-[1,3]thiazolo[4,5-b]pyridine;bis(2-(2-fluoro-6-pyrrolidin-1-yl-3-pyridinyl)-5-(1H-pyrrol-3-yl)-[1,3]thiazolo[4,5-b]pyridine);5-(1-methylpyrazol-4-yl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazole;5-(6-methyl-3-pyridinyl)-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine;4-methyl-1-[2-(6-pyrrolidin-1-yl-3-pyridinyl)-1,3-benzothiazol-6-yl]piperazin-2-one;5-pyridin-3-yl-2-(6-pyrrolidin-1-yl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridine is sourced from PubChem (CID 158376862), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).