4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole

C92H88FN29OS5 — CID 158386169

About 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole

4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole (PubChem CID 158386169) has the molecular formula C92H88FN29OS5 and a molecular weight of 1795.25 g/mol. Its IUPAC name is 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole.

Molecular Properties

• Compound Name: 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole
• PubChem CID: 158386169
• Molecular Formula: C92H88FN29OS5
• Molecular Weight: 1795.25 g/mol
• Exact Mass: 1793.63
• IUPAC Name: 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole
• SMILES: Cc1nn2c(c1-c1nc(C3CCCCC3)c(-c3ncn[nH]3)s1)CCCC2.Cc1nn2ccccc2c1-c1nc(-c2ccc(F)cc2)c(C2=NC=NC2)s1.Cc1nn2ccccc2c1-c1nc(-c2ccoc2)c(-c2ncn[nH]2)s1.Cc1nn2ccccc2c1-c1nc(C(C)(C)C)c(-c2ncn[nH]2)s1.Cc1nn2ccccc2c1-c1nc(C2CCCCC2)c(-c2ncn[nH]2)s1
• InChI: InChI=1S/C20H14FN5S.C19H24N6S.C19H20N6S.C17H12N6OS.C17H18N6S/c1-12-17(16-4-2-3-9-26(16)25-12)20-24-18(13-5-7-14(21)8-6-13)19(27-20)15-10-22-11-23-15;2*1-12-15(14-9-5-6-10-25(14)24-12)19-22-16(13-7-3-2-4-8-13)17(26-19)18-20-11-21-23-18;1-10-13(12-4-2-3-6-23(12)22-10)17-20-14(11-5-7-24-8-11)15(25-17)16-18-9-19-21-16;1-10-12(11-7-5-6-8-23(11)22-10)16-20-14(17(2,3)4)13(24-16)15-18-9-19-21-15/h2-9,11H,10H2,1H3;11,13H,2-10H2,1H3,(H,20,21,23);5-6,9-11,13H,2-4,7-8H2,1H3,(H,20,21,23);2-9H,1H3,(H,18,19,21);5-9H,1-4H3,(H,18,19,21)
• InChIKey: GWKALBBKXYHOMH-UHFFFAOYSA-N
• XLogP: 21.15
• TPSA: 355.61 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 31
• Rotatable Bonds: 14
• Heavy Atoms: 128
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1795.25
LogP ≤ 5	21.15
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole?

The IUPAC name of 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole (CID 158386169) is 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole.

What is the SMILES notation for 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole?

The canonical SMILES for 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole is Cc1nn2c(c1-c1nc(C3CCCCC3)c(-c3ncn[nH]3)s1)CCCC2.Cc1nn2ccccc2c1-c1nc(-c2ccc(F)cc2)c(C2=NC=NC2)s1.Cc1nn2ccccc2c1-c1nc(-c2ccoc2)c(-c2ncn[nH]2)s1.Cc1nn2ccccc2c1-c1nc(C(C)(C)C)c(-c2ncn[nH]2)s1.Cc1nn2ccccc2c1-c1nc(C2CCCCC2)c(-c2ncn[nH]2)s1.

What is the InChIKey of 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole?

The InChIKey is GWKALBBKXYHOMH-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H14FN5S.C19H24N6S.C19H20N6S.C17H12N6OS.C17H18N6S/c1-12-17(16-4-2-3-9-26(16)25-12)20-24-18(13-5-7-14(21)8-6-13)19(27-20)15-10-22-11-23-15;2*1-12-15(14-9-5-6-10-25(14)24-12)19-22-16(13-7-3-2-4-8-13)17(26-19)18-20-11-21-23-18;1-10-13(12-4-2-3-6-23(12)22-10)17-20-14(11-5-7-24-8-11)15(25-17)16-18-9-19-21-16;1-10-12(11-7-5-6-8-23(11)22-10)16-20-14(17(2,3)4)13(24-16)15-18-9-19-21-15/h2-9,11H,10H2,1H3;11,13H,2-10H2,1H3,(H,20,21,23);5-6,9-11,13H,2-4,7-8H2,1H3,(H,20,21,23);2-9H,1H3,(H,18,19,21);5-9H,1-4H3,(H,18,19,21).

What are the key properties of 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole?

4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole has a molecular weight of 1795.25 g/mol, XLogP of 21.15, 14 rotatable bonds, 4 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 4-tert-butyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-cyclohexyl-2-(2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;4-(4-fluorophenyl)-5-(4H-imidazol-5-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(furan-3-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole is sourced from PubChem (CID 158386169), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).