6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen

C138H144F15N27O15S6 — CID 158388907

About 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen

6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen (PubChem CID 158388907) has the molecular formula C138H144F15N27O15S6 and a molecular weight of 2898.22 g/mol. Its IUPAC name is 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen.

Molecular Properties

• Compound Name: 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen
• PubChem CID: 158388907
• Molecular Formula: C138H144F15N27O15S6
• Molecular Weight: 2898.22 g/mol
• Exact Mass: 2895.94
• IUPAC Name: 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen
• SMILES: CC(C)n1c(-c2ncc(S(=O)(=O)N[C@@H](C)C3CC3)cn2)c(C#N)c2ccc(OC(F)F)cc21.CCCn1c(-c2ncc(S(=O)(=O)N[C@@H](C)C3CC3)cn2)c(C#N)c2ccc(OC(F)F)cc21.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2C2CCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(OC(F)F)cc3n2C2CCCC2)nc1)C1CC1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn3)n(C(C)C)c2c1.[H][H].[H][H]
• InChI: InChI=1S/C25H25F3N4O2S.C24H23F3N4O2S.C24H25F2N5O3S.2C22H23F2N5O3S.C21H21F3N4O2S.2H2/c1-15(25(26,27)28)31-35(33,34)19-9-11-22(30-14-19)24-21(13-29)20-10-8-17(16-6-7-16)12-23(20)32(24)18-4-2-3-5-18;1-14(24(25,26)27)30-34(32,33)18-8-10-21(29-13-18)23-20(12-28)19-9-7-16(15-5-6-15)11-22(19)31(23)17-3-2-4-17;1-14(15-6-7-15)30-35(32,33)18-12-28-23(29-13-18)22-20(11-27)19-9-8-17(34-24(25)26)10-21(19)31(22)16-4-2-3-5-16;1-12(2)29-19-8-15(32-22(23)24)6-7-17(19)18(9-25)20(29)21-26-10-16(11-27-21)33(30,31)28-13(3)14-4-5-14;1-3-8-29-19-9-15(32-22(23)24)6-7-17(19)18(10-25)20(29)21-26-11-16(12-27-21)33(30,31)28-13(2)14-4-5-14;1-12(2)28-19-9-13(3)5-7-16(19)17(10-25)20(28)18-8-6-15(11-26-18)31(29,30)27-14(4)21(22,23)24;;/h8-12,14-16,18,31H,2-7H2,1H3;7-11,13-15,17,30H,2-6H2,1H3;8-10,12-16,24,30H,2-7H2,1H3;6-8,10-14,22,28H,4-5H2,1-3H3;6-7,9,11-14,22,28H,3-5,8H2,1-2H3;5-9,11-12,14,27H,1-4H3;2*1H/t15-;2*14-;2*13-;14-;;/m110001../s1
• InChIKey: GWRVMQYYJPGJSW-LVJAAFFFSA-N
• XLogP: 29.44
• TPSA: 593.04 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 36
• Rotatable Bonds: 42
• Heavy Atoms: 201
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2898.22
LogP ≤ 5	29.44
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen?

The IUPAC name of 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen (CID 158388907) is 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen.

What is the SMILES notation for 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen?

The canonical SMILES for 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen is CC(C)n1c(-c2ncc(S(=O)(=O)N[C@@H](C)C3CC3)cn2)c(C#N)c2ccc(OC(F)F)cc21.CCCn1c(-c2ncc(S(=O)(=O)N[C@@H](C)C3CC3)cn2)c(C#N)c2ccc(OC(F)F)cc21.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2C2CCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(OC(F)F)cc3n2C2CCCC2)nc1)C1CC1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn3)n(C(C)C)c2c1.[H][H].[H][H].

What is the InChIKey of 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen?

The InChIKey is GWRVMQYYJPGJSW-LVJAAFFFSA-N. The full InChI is InChI=1S/C25H25F3N4O2S.C24H23F3N4O2S.C24H25F2N5O3S.2C22H23F2N5O3S.C21H21F3N4O2S.2H2/c1-15(25(26,27)28)31-35(33,34)19-9-11-22(30-14-19)24-21(13-29)20-10-8-17(16-6-7-16)12-23(20)32(24)18-4-2-3-5-18;1-14(24(25,26)27)30-34(32,33)18-8-10-21(29-13-18)23-20(12-28)19-9-7-16(15-5-6-15)11-22(19)31(23)17-3-2-4-17;1-14(15-6-7-15)30-35(32,33)18-12-28-23(29-13-18)22-20(11-27)19-9-8-17(34-24(25)26)10-21(19)31(22)16-4-2-3-5-16;1-12(2)29-19-8-15(32-22(23)24)6-7-17(19)18(9-25)20(29)21-26-10-16(11-27-21)33(30,31)28-13(3)14-4-5-14;1-3-8-29-19-9-15(32-22(23)24)6-7-17(19)18(10-25)20(29)21-26-11-16(12-27-21)33(30,31)28-13(2)14-4-5-14;1-12(2)28-19-9-13(3)5-7-16(19)17(10-25)20(28)18-8-6-15(11-26-18)31(29,30)27-14(4)21(22,23)24;;/h8-12,14-16,18,31H,2-7H2,1H3;7-11,13-15,17,30H,2-6H2,1H3;8-10,12-16,24,30H,2-7H2,1H3;6-8,10-14,22,28H,4-5H2,1-3H3;6-7,9,11-14,22,28H,3-5,8H2,1-2H3;5-9,11-12,14,27H,1-4H3;2*1H/t15-;2*14-;2*13-;14-;;/m110001../s1.

What are the key properties of 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen?

6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen has a molecular weight of 2898.22 g/mol, XLogP of 29.44, 42 rotatable bonds, 6 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen is sourced from PubChem (CID 158388907), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).