5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide

C82H61F7N12O3 — CID 158404619

IUPAC5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide
SMILESCc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)cnc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)cnc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5C)ncc34)cnc2C)cc1
InChIInChI=1S/C28H24N4O.C27H17F5N4O.C27H20F2N4O/c1-18-10-12-22(13-11-18)31-28(33)25-15-21(16-29-20(25)3)24-9-6-14-32-26(24)17-30-27(32)23-8-5-4-7-19(23)2;1-15-7-9-17(10-8-15)35-26(37)20-12-16(13-33-24(20)27(30,31)32)18-5-3-11-36-22(18)14-34-25(36)19-4-2-6-21(28)23(19)29;1-16-8-10-19(11-9-16)32-27(34)22-13-18(14-30-17(22)2)20-6-4-12-33-24(20)15-31-26(33)21-5-3-7-23(28)25(21)29/h4-17H,1-3H3,(H,31,33);2-14H,1H3,(H,35,37);3-15H,1-2H3,(H,32,34)
InChIKeyGYNHVFDXYKCOQS-UHFFFAOYSA-N
MW1395.46 g/mol
LogP19.37
Rot. Bonds12

About 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide

5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide (PubChem CID 158404619) has the molecular formula C82H61F7N12O3 and a molecular weight of 1395.46 g/mol. Its IUPAC name is 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide.

Molecular Properties

Compound Name5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide
PubChem CID158404619
Molecular FormulaC82H61F7N12O3
Molecular Weight1395.46 g/mol
Exact Mass1394.49
IUPAC Name5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide
SMILESCc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)cnc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)cnc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5C)ncc34)cnc2C)cc1
InChIInChI=1S/C28H24N4O.C27H17F5N4O.C27H20F2N4O/c1-18-10-12-22(13-11-18)31-28(33)25-15-21(16-29-20(25)3)24-9-6-14-32-26(24)17-30-27(32)23-8-5-4-7-19(23)2;1-15-7-9-17(10-8-15)35-26(37)20-12-16(13-33-24(20)27(30,31)32)18-5-3-11-36-22(18)14-34-25(36)19-4-2-6-21(28)23(19)29;1-16-8-10-19(11-9-16)32-27(34)22-13-18(14-30-17(22)2)20-6-4-12-33-24(20)15-31-26(33)21-5-3-7-23(28)25(21)29/h4-17H,1-3H3,(H,31,33);2-14H,1H3,(H,35,37);3-15H,1-2H3,(H,32,34)
InChIKeyGYNHVFDXYKCOQS-UHFFFAOYSA-N
XLogP19.37
TPSA177.87 Ų
H-Bond Donors3
H-Bond Acceptors12
Rotatable Bonds12
Heavy Atoms104
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001395.46
LogP ≤ 519.37
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1012

Analyze 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide with MolForge

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Related Compounds

N-(4-{5-[3-(Acetylamino)phenyl]-2-(2-Aminopyridin-3-Yl)-3h-Imidazo[4,5-B]pyridin-3-Yl}benzyl)-3-Fluorobenzamide
CID 56965952
N-(2,6-difluorophenyl)-3-[3-[2-[4-(4-piperidin-1-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
CID 44571813
US11203591, Example 213
CID 149214214
US11203591, Example 185
CID 153091936
US11203591, Example 217
CID 153578677
US11203591, Example 220
CID 153578763
US11203591, Example 222
CID 153578769
US11203591, Example 19
CID 153578774
US11203591, Example 67
CID 153578800
US11203591, Example 186
CID 153578818
US11203591, Example 214
CID 153578819
US11203591, Example 216
CID 153578870

Frequently Asked Questions

What is the IUPAC name of 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide?
The IUPAC name of 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide (CID 158404619) is 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide.
What is the SMILES notation for 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide?
The canonical SMILES for 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide is Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)cnc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)cnc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ccccc5C)ncc34)cnc2C)cc1.
What is the InChIKey of 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide?
The InChIKey is GYNHVFDXYKCOQS-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H24N4O.C27H17F5N4O.C27H20F2N4O/c1-18-10-12-22(13-11-18)31-28(33)25-15-21(16-29-20(25)3)24-9-6-14-32-26(24)17-30-27(32)23-8-5-4-7-19(23)2;1-15-7-9-17(10-8-15)35-26(37)20-12-16(13-33-24(20)27(30,31)32)18-5-3-11-36-22(18)14-34-25(36)19-4-2-6-21(28)23(19)29;1-16-8-10-19(11-9-16)32-27(34)22-13-18(14-30-17(22)2)20-6-4-12-33-24(20)15-31-26(33)21-5-3-7-23(28)25(21)29/h4-17H,1-3H3,(H,31,33);2-14H,1H3,(H,35,37);3-15H,1-2H3,(H,32,34).
What are the key properties of 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide?
5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide has a molecular weight of 1395.46 g/mol, XLogP of 19.37, 12 rotatable bonds, 3 hydrogen bond donors, and 12 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide;2-methyl-N-(4-methylphenyl)-5-[3-(2-methylphenyl)imidazo[1,5-a]pyridin-8-yl]pyridine-3-carboxamide is sourced from PubChem (CID 158404619), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).