2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide

C60H71Cl2N15O5Si2 — CID 158408870

About 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide

2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide (PubChem CID 158408870) has the molecular formula C60H71Cl2N15O5Si2 and a molecular weight of 1209.41 g/mol. Its IUPAC name is 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide.

Molecular Properties

• Compound Name: 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide
• PubChem CID: 158408870
• Molecular Formula: C60H71Cl2N15O5Si2
• Molecular Weight: 1209.41 g/mol
• Exact Mass: 1207.47
• IUPAC Name: 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide
• SMILES: CC(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3n[nH]c4cc(Cl)ccc34)nc12)c1cccnc1.CC(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(CCN4CCOCC4)c4cc(Cl)ccc34)nc12)c1cccnc1
• InChI: InChI=1S/C33H41ClN8O3Si.C27H30ClN7O2Si/c1-23(24-6-5-9-35-19-24)37-33(43)27-21-41(22-45-16-17-46(2,3)4)32-31(27)38-28(20-36-32)30-26-8-7-25(34)18-29(26)42(39-30)11-10-40-12-14-44-15-13-40;1-17(18-6-5-9-29-13-18)31-27(36)21-15-35(16-37-10-11-38(2,3)4)26-25(21)32-23(14-30-26)24-20-8-7-19(28)12-22(20)33-34-24/h5-9,18-21,23H,10-17,22H2,1-4H3,(H,37,43);5-9,12-15,17H,10-11,16H2,1-4H3,(H,31,36)(H,33,34)
• InChIKey: GZAWQAHYXAFDRO-UHFFFAOYSA-N
• XLogP: 11.46
• TPSA: 222.83 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 17
• Rotatable Bonds: 21
• Heavy Atoms: 84
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1209.41
LogP ≤ 5	11.46
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	17

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide?

The IUPAC name of 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide (CID 158408870) is 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide.

What is the SMILES notation for 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide?

The canonical SMILES for 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide is CC(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3n[nH]c4cc(Cl)ccc34)nc12)c1cccnc1.CC(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(CCN4CCOCC4)c4cc(Cl)ccc34)nc12)c1cccnc1.

What is the InChIKey of 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide?

The InChIKey is GZAWQAHYXAFDRO-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H41ClN8O3Si.C27H30ClN7O2Si/c1-23(24-6-5-9-35-19-24)37-33(43)27-21-41(22-45-16-17-46(2,3)4)32-31(27)38-28(20-36-32)30-26-8-7-25(34)18-29(26)42(39-30)11-10-40-12-14-44-15-13-40;1-17(18-6-5-9-29-13-18)31-27(36)21-15-35(16-37-10-11-38(2,3)4)26-25(21)32-23(14-30-26)24-20-8-7-19(28)12-22(20)33-34-24/h5-9,18-21,23H,10-17,22H2,1-4H3,(H,37,43);5-9,12-15,17H,10-11,16H2,1-4H3,(H,31,36)(H,33,34).

What are the key properties of 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide?

2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide has a molecular weight of 1209.41 g/mol, XLogP of 11.46, 21 rotatable bonds, 3 hydrogen bond donors, and 17 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(6-chloro-1H-indazol-3-yl)-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide;2-[6-chloro-1-(2-morpholin-4-ylethyl)indazol-3-yl]-N-(1-pyridin-3-ylethyl)-5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazine-7-carboxamide is sourced from PubChem (CID 158408870), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).