6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide

C156H166F13N29O19 — CID 158411284

IUPAC6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide
SMILESCOc1ncc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)nnc2C)cc1N1CCOCC1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cncc(C(F)(F)F)c2)cc1-c1cnc(OCC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cnnc(C3(C#N)CC3)c2)cc1-c1cnc(OCC(F)F)c(N2CCOCC2)c1
InChIInChI=1S/C28H33FN4O3.C28H34N4O4.C27H30F2N4O3.C26H25F2N7O3.C24H22F5N5O3.C23H22F3N5O3/c1-18(2)36-27-24(33-10-12-35-13-11-33)14-21(17-31-27)23-16-22(7-6-19(23)3)32-26(34)20-8-9-30-25(15-20)28(4,5)29;1-18(2)36-27-24(32-10-12-35-13-11-32)14-21(17-30-27)23-16-22(7-6-19(23)3)31-26(33)20-8-9-29-25(15-20)28(4,5)34;1-17(2)36-26-23(33-9-11-35-12-10-33)13-20(16-31-26)22-15-21(6-5-18(22)3)32-25(34)19-7-8-30-24(14-19)27(4,28)29;1-16-20(17-8-21(35-4-6-37-7-5-35)25(31-11-17)38-14-23(27)28)10-19(13-30-16)33-24(36)18-9-22(34-32-12-18)26(15-29)2-3-26;1-14-19(8-18(12-31-14)33-22(35)16-6-17(11-30-9-16)24(27,28)29)15-7-20(34-2-4-36-5-3-34)23(32-10-15)37-13-21(25)26;1-14-18(16-11-19(22(33-2)27-13-16)31-6-8-34-9-7-31)12-20(30-29-14)28-21(32)15-4-3-5-17(10-15)23(24,25)26/h6-9,14-18H,10-13H2,1-5H3,(H,32,34);6-9,14-18,34H,10-13H2,1-5H3,(H,31,33);5-8,13-17H,9-12H2,1-4H3,(H,32,34);8-13,23H,2-7,14H2,1H3,(H,33,36);6-12,21H,2-5,13H2,1H3,(H,33,35);3-5,10-13H,6-9H2,1-2H3,(H,28,30,32)
InChIKeyGZIPFPBYXVDPFL-UHFFFAOYSA-N
MW2998.20 g/mol
LogP27.62
Rot. Bonds41

About 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide

6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide (PubChem CID 158411284) has the molecular formula C156H166F13N29O19 and a molecular weight of 2998.20 g/mol. Its IUPAC name is 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide.

Molecular Properties

Compound Name6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide
PubChem CID158411284
Molecular FormulaC156H166F13N29O19
Molecular Weight2998.20 g/mol
Exact Mass2996.27
IUPAC Name6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide
SMILESCOc1ncc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)nnc2C)cc1N1CCOCC1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cncc(C(F)(F)F)c2)cc1-c1cnc(OCC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cnnc(C3(C#N)CC3)c2)cc1-c1cnc(OCC(F)F)c(N2CCOCC2)c1
InChIInChI=1S/C28H33FN4O3.C28H34N4O4.C27H30F2N4O3.C26H25F2N7O3.C24H22F5N5O3.C23H22F3N5O3/c1-18(2)36-27-24(33-10-12-35-13-11-33)14-21(17-31-27)23-16-22(7-6-19(23)3)32-26(34)20-8-9-30-25(15-20)28(4,5)29;1-18(2)36-27-24(32-10-12-35-13-11-32)14-21(17-30-27)23-16-22(7-6-19(23)3)31-26(33)20-8-9-29-25(15-20)28(4,5)34;1-17(2)36-26-23(33-9-11-35-12-10-33)13-20(16-31-26)22-15-21(6-5-18(22)3)32-25(34)19-7-8-30-24(14-19)27(4,28)29;1-16-20(17-8-21(35-4-6-37-7-5-35)25(31-11-17)38-14-23(27)28)10-19(13-30-16)33-24(36)18-9-22(34-32-12-18)26(15-29)2-3-26;1-14-19(8-18(12-31-14)33-22(35)16-6-17(11-30-9-16)24(27,28)29)15-7-20(34-2-4-36-5-3-34)23(32-10-15)37-13-21(25)26;1-14-18(16-11-19(22(33-2)27-13-16)31-6-8-34-9-7-31)12-20(30-29-14)28-21(32)15-4-3-5-17(10-15)23(24,25)26/h6-9,14-18H,10-13H2,1-5H3,(H,32,34);6-9,14-18,34H,10-13H2,1-5H3,(H,31,33);5-8,13-17H,9-12H2,1-4H3,(H,32,34);8-13,23H,2-7,14H2,1H3,(H,33,36);6-12,21H,2-5,13H2,1H3,(H,33,35);3-5,10-13H,6-9H2,1-2H3,(H,28,30,32)
InChIKeyGZIPFPBYXVDPFL-UHFFFAOYSA-N
XLogP27.62
TPSA555.06 Ų
H-Bond Donors7
H-Bond Acceptors42
Rotatable Bonds41
Heavy Atoms217
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002998.20
LogP ≤ 527.62
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1042

Analyze 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide with MolForge

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Launch Full Analysis

Related Compounds

N-[3-[6-ethoxy-5-[2-[2-[6-[5-[[2-(2-hydroxypropan-2-yl)pyridine-4-carbonyl]amino]-2-methylphenyl]-4-morpholin-4-ylpyridazin-3-yl]oxyethyl]morpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide
CID 130425574
2-(2-cyanopropan-2-yl)-N-[3-[5-[(3R)-2-[2-[6-[5-[[2-(2-cyanopropan-2-yl)pyridine-4-carbonyl]amino]-2-methyl-3-pyridinyl]-4-[(3R)-3-methyl-2-[2-[4-[(3R)-3-methylmorpholin-4-yl]-6-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]-3-pyridinyl]pyridazin-3-yl]oxyethyl]morpholin-4-yl]pyridazin-3-yl]oxyethyl]-3-methylmorpholin-4-yl]-6-ethoxypyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425581
6-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[2-[2-[6-[2-methyl-5-[[2-(trifluoromethyl)pyridine-4-carbonyl]amino]phenyl]-4-morpholin-4-ylpyridazin-3-yl]oxyethyl]morpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridazine-4-carboxamide
CID 130425658
6-(2-cyanopropan-2-yl)-N-[3-[4-[[4-[5-[[2-(2-cyanopropan-2-yl)pyridine-4-carbonyl]amino]-3-[4-[[4-[5-[[2-(difluoromethyl)pyridine-4-carbonyl]amino]-2-methylphenyl]-6-morpholin-4-yl-2-pyridinyl]oxy]oxan-2-yl]-2-methylphenyl]-6-morpholin-4-yl-2-pyridinyl]oxy]oxan-2-yl]-4-methyl-5-[2-morpholin-4-yl-6-(oxan-4-yloxy)-4-pyridinyl]phenyl]pyridazine-4-carboxamide
CID 130425662
N-[5-[6-(2,2-difluoroethoxy)-5-[2-[[5-[3-methyl-6-[[3-(trifluoromethyl)benzoyl]amino]pyridazin-4-yl]-3-morpholin-4-ylpyridin-2-yl]oxymethyl]morpholin-4-yl]pyridin-3-yl]-6-methylpyridin-3-yl]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 130425809
6-[4-[2-[5-[2-Methyl-5-[[3-(trifluoromethyl)benzoyl]amino]pyridin-3-yl]-3-morpholin-4-ylpyridin-2-yl]oxyethyl]piperazin-1-yl]pyridazine-3-carboxylic acid
CID 154684355
6-(2-cyanopropan-2-yl)-N-[3-[3-fluoro-6-(2-hydroxyethylamino)-2-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridazine-4-carboxamide;N-[3-[3,5-difluoro-2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[3,5-difluoro-2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(difluoromethyl)-N-[3-[3-fluoro-2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[3-fluoro-6-(2-hydroxyethylamino)-2-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;1-[3-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-[2-(trifluoromethyl)-4-pyridinyl]ethanone
CID 157072500
N-[3-[2-[bis(2-hydroxyethyl)amino]-6-(oxan-4-yl)-4-pyridinyl]-4-methylphenyl]-2-(2-cyanopropan-2-yl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-(oxan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-[2-(2-hydroxyethylamino)-6-(oxan-4-yl)-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[6-ethoxy-5-(oxan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[2-(2-hydroxyethylamino)-6-(oxan-4-yl)-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157194733
2-(1-cyanocyclopropyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridazine-4-carboxamide;2-cyclopropyl-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-2-fluoro-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157274240
2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-ethyl-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-methyl-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-N-propyl-3-(trifluoromethyl)benzamide
CID 157325132
2-(2-cyanopropan-2-yl)-N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;1-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-[3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl]ethanone;1-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-[3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl]ethanone;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[6-methyl-5-[6-(1-methylpiperidin-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157397421
N-[3-[2-(2-hydroxyethoxy)-6-(4-hydroxyoxan-4-yl)-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[2-(2-hydroxyethylamino)-6-(4-hydroxyoxan-4-yl)-4-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[2-(2-hydroxyethylamino)-6-(4-hydroxyoxan-4-yl)-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[2-hydroxyethyl(methyl)amino]-5-(oxan-4-yl)pyridazin-3-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[6-[[(2R)-1-hydroxypropan-2-yl]amino]-5-(oxan-4-yl)pyridazin-3-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[6-[[(2S)-1-hydroxypropan-2-yl]amino]-5-(oxan-4-yl)pyridazin-3-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157740306

Frequently Asked Questions

What is the IUPAC name of 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide?
The IUPAC name of 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide (CID 158411284) is 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide.
What is the SMILES notation for 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide?
The canonical SMILES for 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide is COc1ncc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)nnc2C)cc1N1CCOCC1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cncc(C(F)(F)F)c2)cc1-c1cnc(OCC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cnnc(C3(C#N)CC3)c2)cc1-c1cnc(OCC(F)F)c(N2CCOCC2)c1.
What is the InChIKey of 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide?
The InChIKey is GZIPFPBYXVDPFL-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H33FN4O3.C28H34N4O4.C27H30F2N4O3.C26H25F2N7O3.C24H22F5N5O3.C23H22F3N5O3/c1-18(2)36-27-24(33-10-12-35-13-11-33)14-21(17-31-27)23-16-22(7-6-19(23)3)32-26(34)20-8-9-30-25(15-20)28(4,5)29;1-18(2)36-27-24(32-10-12-35-13-11-32)14-21(17-30-27)23-16-22(7-6-19(23)3)31-26(33)20-8-9-29-25(15-20)28(4,5)34;1-17(2)36-26-23(33-9-11-35-12-10-33)13-20(16-31-26)22-15-21(6-5-18(22)3)32-25(34)19-7-8-30-24(14-19)27(4,28)29;1-16-20(17-8-21(35-4-6-37-7-5-35)25(31-11-17)38-14-23(27)28)10-19(13-30-16)33-24(36)18-9-22(34-32-12-18)26(15-29)2-3-26;1-14-19(8-18(12-31-14)33-22(35)16-6-17(11-30-9-16)24(27,28)29)15-7-20(34-2-4-36-5-3-34)23(32-10-15)37-13-21(25)26;1-14-18(16-11-19(22(33-2)27-13-16)31-6-8-34-9-7-31)12-20(30-29-14)28-21(32)15-4-3-5-17(10-15)23(24,25)26/h6-9,14-18H,10-13H2,1-5H3,(H,32,34);6-9,14-18,34H,10-13H2,1-5H3,(H,31,33);5-8,13-17H,9-12H2,1-4H3,(H,32,34);8-13,23H,2-7,14H2,1H3,(H,33,36);6-12,21H,2-5,13H2,1H3,(H,33,35);3-5,10-13H,6-9H2,1-2H3,(H,28,30,32).
What are the key properties of 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide?
6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide has a molecular weight of 2998.20 g/mol, XLogP of 27.62, 41 rotatable bonds, 7 hydrogen bond donors, and 42 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(1-cyanocyclopropyl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methylpyridazin-3-yl]-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 158411284), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).