(3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol

C134H123Cl5F2N22O14 — CID 158419586

IUPAC(3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol
SMILESC[C@@H](O)[C@H]1COC(Cc2ccc3ncnc(Nc4ccc(Oc5ccccc5F)c(Cl)c4)c3c2)=N1.C[C@H](O)[C@]1(C)CN=C(Cc2ccc3ncnc(Nc4ccc(OCC5=NC=CC5)c(Cl)c4)c3c2)O1.C[C@H](O)[C@]1(C)CN=C(Cc2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)O1.Cc1cccc(COc2ccc(Nc3ncnc4ccc(CC5=N[C@@H]6C[C@@H](O)C[C@@H]6O5)cc34)cc2Cl)c1.Cc1cncc(COc2ccc(Nc3ncnc4ccc(CC5=NCCO5)cc34)cc2Cl)c1
InChIInChI=1S/C29H27ClN4O3.C28H26ClFN4O3.C26H22ClFN4O3.C26H26ClN5O3.C25H22ClN5O2/c1-17-3-2-4-19(9-17)15-36-26-8-6-20(12-23(26)30)33-29-22-10-18(5-7-24(22)31-16-32-29)11-28-34-25-13-21(35)14-27(25)37-28;1-17(35)28(2)15-31-26(37-28)12-18-6-8-24-22(11-18)27(33-16-32-24)34-21-7-9-25(23(29)13-21)36-14-19-4-3-5-20(30)10-19;1-15(33)22-13-34-25(32-22)11-16-6-8-21-18(10-16)26(30-14-29-21)31-17-7-9-23(19(27)12-17)35-24-5-3-2-4-20(24)28;1-16(33)26(2)14-29-24(35-26)11-17-5-7-22-20(10-17)25(31-15-30-22)32-18-6-8-23(21(27)12-18)34-13-19-4-3-9-28-19;1-16-8-18(13-27-12-16)14-33-23-5-3-19(11-21(23)26)31-25-20-9-17(10-24-28-6-7-32-24)2-4-22(20)29-15-30-25/h2-10,12,16,21,25,27,35H,11,13-15H2,1H3,(H,31,32,33);3-11,13,16-17,35H,12,14-15H2,1-2H3,(H,32,33,34);2-10,12,14-15,22,33H,11,13H2,1H3,(H,29,30,31);3,5-10,12,15-16,33H,4,11,13-14H2,1-2H3,(H,30,31,32);2-5,8-9,11-13,15H,6-7,10,14H2,1H3,(H,29,30,31)/t21-,25-,27+;17-,28-;15-,22-;16-,26-;/m1010./s1
InChIKeyHAICYQPGCYVTSL-RNQMWBDNSA-N
MW2480.86 g/mol
LogP27.47
Rot. Bonds37

About (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol

(3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol (PubChem CID 158419586) has the molecular formula C134H123Cl5F2N22O14 and a molecular weight of 2480.86 g/mol. Its IUPAC name is (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol.

Molecular Properties

Compound Name(3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol
PubChem CID158419586
Molecular FormulaC134H123Cl5F2N22O14
Molecular Weight2480.86 g/mol
Exact Mass2476.80
IUPAC Name(3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol
SMILESC[C@@H](O)[C@H]1COC(Cc2ccc3ncnc(Nc4ccc(Oc5ccccc5F)c(Cl)c4)c3c2)=N1.C[C@H](O)[C@]1(C)CN=C(Cc2ccc3ncnc(Nc4ccc(OCC5=NC=CC5)c(Cl)c4)c3c2)O1.C[C@H](O)[C@]1(C)CN=C(Cc2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)O1.Cc1cccc(COc2ccc(Nc3ncnc4ccc(CC5=N[C@@H]6C[C@@H](O)C[C@@H]6O5)cc34)cc2Cl)c1.Cc1cncc(COc2ccc(Nc3ncnc4ccc(CC5=NCCO5)cc34)cc2Cl)c1
InChIInChI=1S/C29H27ClN4O3.C28H26ClFN4O3.C26H22ClFN4O3.C26H26ClN5O3.C25H22ClN5O2/c1-17-3-2-4-19(9-17)15-36-26-8-6-20(12-23(26)30)33-29-22-10-18(5-7-24(22)31-16-32-29)11-28-34-25-13-21(35)14-27(25)37-28;1-17(35)28(2)15-31-26(37-28)12-18-6-8-24-22(11-18)27(33-16-32-24)34-21-7-9-25(23(29)13-21)36-14-19-4-3-5-20(30)10-19;1-15(33)22-13-34-25(32-22)11-16-6-8-21-18(10-16)26(30-14-29-21)31-17-7-9-23(19(27)12-17)35-24-5-3-2-4-20(24)28;1-16(33)26(2)14-29-24(35-26)11-17-5-7-22-20(10-17)25(31-15-30-22)32-18-6-8-23(21(27)12-18)34-13-19-4-3-9-28-19;1-16-8-18(13-27-12-16)14-33-23-5-3-19(11-21(23)26)31-25-20-9-17(10-24-28-6-7-32-24)2-4-22(20)29-15-30-25/h2-10,12,16,21,25,27,35H,11,13-15H2,1H3,(H,31,32,33);3-11,13,16-17,35H,12,14-15H2,1-2H3,(H,32,33,34);2-10,12,14-15,22,33H,11,13H2,1H3,(H,29,30,31);3,5-10,12,15-16,33H,4,11,13-14H2,1-2H3,(H,30,31,32);2-5,8-9,11-13,15H,6-7,10,14H2,1H3,(H,29,30,31)/t21-,25-,27+;17-,28-;15-,22-;16-,26-;/m1010./s1
InChIKeyHAICYQPGCYVTSL-RNQMWBDNSA-N
XLogP27.47
TPSA449.32 Ų
H-Bond Donors9
H-Bond Acceptors36
Rotatable Bonds37
Heavy Atoms177
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002480.86
LogP ≤ 527.47
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1036

Analyze (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol with MolForge

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Frequently Asked Questions

What is the IUPAC name of (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol?
The IUPAC name of (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol (CID 158419586) is (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol.
What is the SMILES notation for (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol?
The canonical SMILES for (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol is C[C@@H](O)[C@H]1COC(Cc2ccc3ncnc(Nc4ccc(Oc5ccccc5F)c(Cl)c4)c3c2)=N1.C[C@H](O)[C@]1(C)CN=C(Cc2ccc3ncnc(Nc4ccc(OCC5=NC=CC5)c(Cl)c4)c3c2)O1.C[C@H](O)[C@]1(C)CN=C(Cc2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)O1.Cc1cccc(COc2ccc(Nc3ncnc4ccc(CC5=N[C@@H]6C[C@@H](O)C[C@@H]6O5)cc34)cc2Cl)c1.Cc1cncc(COc2ccc(Nc3ncnc4ccc(CC5=NCCO5)cc34)cc2Cl)c1.
What is the InChIKey of (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol?
The InChIKey is HAICYQPGCYVTSL-RNQMWBDNSA-N. The full InChI is InChI=1S/C29H27ClN4O3.C28H26ClFN4O3.C26H22ClFN4O3.C26H26ClN5O3.C25H22ClN5O2/c1-17-3-2-4-19(9-17)15-36-26-8-6-20(12-23(26)30)33-29-22-10-18(5-7-24(22)31-16-32-29)11-28-34-25-13-21(35)14-27(25)37-28;1-17(35)28(2)15-31-26(37-28)12-18-6-8-24-22(11-18)27(33-16-32-24)34-21-7-9-25(23(29)13-21)36-14-19-4-3-5-20(30)10-19;1-15(33)22-13-34-25(32-22)11-16-6-8-21-18(10-16)26(30-14-29-21)31-17-7-9-23(19(27)12-17)35-24-5-3-2-4-20(24)28;1-16(33)26(2)14-29-24(35-26)11-17-5-7-22-20(10-17)25(31-15-30-22)32-18-6-8-23(21(27)12-18)34-13-19-4-3-9-28-19;1-16-8-18(13-27-12-16)14-33-23-5-3-19(11-21(23)26)31-25-20-9-17(10-24-28-6-7-32-24)2-4-22(20)29-15-30-25/h2-10,12,16,21,25,27,35H,11,13-15H2,1H3,(H,31,32,33);3-11,13,16-17,35H,12,14-15H2,1-2H3,(H,32,33,34);2-10,12,14-15,22,33H,11,13H2,1H3,(H,29,30,31);3,5-10,12,15-16,33H,4,11,13-14H2,1-2H3,(H,30,31,32);2-5,8-9,11-13,15H,6-7,10,14H2,1H3,(H,29,30,31)/t21-,25-,27+;17-,28-;15-,22-;16-,26-;/m1010./s1.
What are the key properties of (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol?
(3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol has a molecular weight of 2480.86 g/mol, XLogP of 27.47, 37 rotatable bonds, 9 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for (3aR,5R,6aS)-2-[[4-[3-chloro-4-[(3-methylphenyl)methoxy]anilino]quinazolin-6-yl]methyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazol-5-ol;(1R)-1-[(4R)-2-[[4-[3-chloro-4-(2-fluorophenoxy)anilino]quinazolin-6-yl]methyl]-4,5-dihydro-1,3-oxazol-4-yl]ethanol;(1S)-1-[(5S)-2-[[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol;N-[3-chloro-4-[(5-methyl-3-pyridinyl)methoxy]phenyl]-6-(4,5-dihydro-1,3-oxazol-2-ylmethyl)quinazolin-4-amine;(1S)-1-[(5S)-2-[[4-[3-chloro-4-(3H-pyrrol-2-ylmethoxy)anilino]quinazolin-6-yl]methyl]-5-methyl-4H-1,3-oxazol-5-yl]ethanol is sourced from PubChem (CID 158419586), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).