5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide

C86H84F5N21O14S4 — CID 158424458

IUPAC5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide
SMILESCC(=O)Cc1cc(-c2cnc(N)c(S(=O)(=O)Nc3ccc(F)cc3F)c2)ccn1.CC(=O)Nc1cc(-c2cnc(C)c(CS(=O)(=O)c3cccc(C(F)(F)F)c3)c2)ccn1.CC(=O)Nc1cc(-c2cnc(C)c(CS(C)(=O)=O)c2)ccn1.CC(=O)Nc1cc(-c2cnc(N)c(C(=O)NC3CC3)c2)ccn1.CN(C)S(=O)(=O)c1cc(-c2ccnc(Nc3ncco3)c2)cnc1N
InChIInChI=1S/C21H18F3N3O3S.C19H16F2N4O3S.C16H17N5O2.C15H16N6O3S.C15H17N3O3S/c1-13-17(12-31(29,30)19-5-3-4-18(10-19)21(22,23)24)8-16(11-26-13)15-6-7-25-20(9-15)27-14(2)28;1-11(26)6-15-7-12(4-5-23-15)13-8-18(19(22)24-10-13)29(27,28)25-17-3-2-14(20)9-16(17)21;1-9(22)20-14-7-10(4-5-18-14)11-6-13(15(17)19-8-11)16(23)21-12-2-3-12;1-21(2)25(22,23)12-7-11(9-19-14(12)16)10-3-4-17-13(8-10)20-15-18-5-6-24-15;1-10-14(9-22(3,20)21)6-13(8-17-10)12-4-5-16-15(7-12)18-11(2)19/h3-11H,12H2,1-2H3,(H,25,27,28);2-5,7-10,25H,6H2,1H3,(H2,22,24);4-8,12H,2-3H2,1H3,(H2,17,19)(H,21,23)(H,18,20,22);3-9H,1-2H3,(H2,16,19)(H,17,18,20);4-8H,9H2,1-3H3,(H,16,18,19)
InChIKeyHAWOOQREBDRXNQ-UHFFFAOYSA-N
MW1859.01 g/mol
LogP12.58
Rot. Bonds24

About 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide

5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide (PubChem CID 158424458) has the molecular formula C86H84F5N21O14S4 and a molecular weight of 1859.01 g/mol. Its IUPAC name is 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide.

Molecular Properties

Compound Name5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide
PubChem CID158424458
Molecular FormulaC86H84F5N21O14S4
Molecular Weight1859.01 g/mol
Exact Mass1857.53
IUPAC Name5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide
SMILESCC(=O)Cc1cc(-c2cnc(N)c(S(=O)(=O)Nc3ccc(F)cc3F)c2)ccn1.CC(=O)Nc1cc(-c2cnc(C)c(CS(=O)(=O)c3cccc(C(F)(F)F)c3)c2)ccn1.CC(=O)Nc1cc(-c2cnc(C)c(CS(C)(=O)=O)c2)ccn1.CC(=O)Nc1cc(-c2cnc(N)c(C(=O)NC3CC3)c2)ccn1.CN(C)S(=O)(=O)c1cc(-c2ccnc(Nc3ncco3)c2)cnc1N
InChIInChI=1S/C21H18F3N3O3S.C19H16F2N4O3S.C16H17N5O2.C15H16N6O3S.C15H17N3O3S/c1-13-17(12-31(29,30)19-5-3-4-18(10-19)21(22,23)24)8-16(11-26-13)15-6-7-25-20(9-15)27-14(2)28;1-11(26)6-15-7-12(4-5-23-15)13-8-18(19(22)24-10-13)29(27,28)25-17-3-2-14(20)9-16(17)21;1-9(22)20-14-7-10(4-5-18-14)11-6-13(15(17)19-8-11)16(23)21-12-2-3-12;1-21(2)25(22,23)12-7-11(9-19-14(12)16)10-3-4-17-13(8-10)20-15-18-5-6-24-15;1-10-14(9-22(3,20)21)6-13(8-17-10)12-4-5-16-15(7-12)18-11(2)19/h3-11H,12H2,1-2H3,(H,25,27,28);2-5,7-10,25H,6H2,1H3,(H2,22,24);4-8,12H,2-3H2,1H3,(H2,17,19)(H,21,23)(H,18,20,22);3-9H,1-2H3,(H2,16,19)(H,17,18,20);4-8H,9H2,1-3H3,(H,16,18,19)
InChIKeyHAWOOQREBDRXNQ-UHFFFAOYSA-N
XLogP12.58
TPSA530.32 Ų
H-Bond Donors9
H-Bond Acceptors29
Rotatable Bonds24
Heavy Atoms130
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001859.01
LogP ≤ 512.58
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1029

Analyze 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

5-(2-acetamido-4-pyridinyl)-2-amino-N-pyridin-3-ylpyridine-3-carboxamide;2-amino-N-methyl-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-(6-amino-5-pyrrolidin-1-ylsulfonyl-3-pyridinyl)-2-pyridinyl]acetamide;N-[4-[5-(1,1-dioxo-1,2-thiazolidin-2-yl)-6-methyl-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[3-fluoro-4-[[2-methyl-5-[2-(2-oxopropyl)-4-pyridinyl]-3-pyridinyl]sulfamoyl]phenyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[4-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide
CID 157200652
N-[4-(6-amino-5-benzylsulfonyl-3-pyridinyl)-2-pyridinyl]acetamide;N-[4-[6-amino-5-(piperidine-1-carbonyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-amino-5-(propan-2-ylsulfamoyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[5-(cyclopropanecarbonyl)-3-pyridinyl]-2-pyridinyl]acetamide;1-[4-[5-(4,4-difluoropiperidin-1-yl)sulfonyl-3-pyridinyl]-2-pyridinyl]propan-2-one
CID 162193320
N-[4-[6-amino-5-(cyclohexylmethylsulfamoyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-amino-5-(dimethylsulfamoyl)-3-pyridinyl]-5-fluoro-2-pyridinyl]acetamide;1-[4-[6-amino-5-(1,1-dioxo-1,2-thiazolidin-2-yl)-3-pyridinyl]-2-pyridinyl]propan-2-one;N-[4-[5-[(2-fluoro-4-methylphenyl)sulfonylamino]-6-methyl-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[5-[(4-fluorophenyl)sulfonylmethyl]-6-methyl-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-(5-formyl-3-pyridinyl)-2-pyridinyl]acetamide
CID 160306625
5-(2-acetamido-4-pyridinyl)-2-amino-N,N-diethylpyridine-3-carboxamide;N-[4-(6-amino-5-morpholin-4-ylsulfonyl-3-pyridinyl)-2-pyridinyl]acetamide;N-[4-[1-(benzenesulfonyl)pyrrolo[3,2-b]pyridin-6-yl]-2-pyridinyl]acetamide;N-[4-[5-[cyclopropylsulfonyl(ethyl)amino]-6-methyl-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[5-[(2,4-difluorophenyl)sulfonylmethyl]-6-(dimethylamino)-3-pyridinyl]-2-pyridinyl]acetamide
CID 160730044

Frequently Asked Questions

What is the IUPAC name of 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide?
The IUPAC name of 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide (CID 158424458) is 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide.
What is the SMILES notation for 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide?
The canonical SMILES for 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide is CC(=O)Cc1cc(-c2cnc(N)c(S(=O)(=O)Nc3ccc(F)cc3F)c2)ccn1.CC(=O)Nc1cc(-c2cnc(C)c(CS(=O)(=O)c3cccc(C(F)(F)F)c3)c2)ccn1.CC(=O)Nc1cc(-c2cnc(C)c(CS(C)(=O)=O)c2)ccn1.CC(=O)Nc1cc(-c2cnc(N)c(C(=O)NC3CC3)c2)ccn1.CN(C)S(=O)(=O)c1cc(-c2ccnc(Nc3ncco3)c2)cnc1N.
What is the InChIKey of 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide?
The InChIKey is HAWOOQREBDRXNQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H18F3N3O3S.C19H16F2N4O3S.C16H17N5O2.C15H16N6O3S.C15H17N3O3S/c1-13-17(12-31(29,30)19-5-3-4-18(10-19)21(22,23)24)8-16(11-26-13)15-6-7-25-20(9-15)27-14(2)28;1-11(26)6-15-7-12(4-5-23-15)13-8-18(19(22)24-10-13)29(27,28)25-17-3-2-14(20)9-16(17)21;1-9(22)20-14-7-10(4-5-18-14)11-6-13(15(17)19-8-11)16(23)21-12-2-3-12;1-21(2)25(22,23)12-7-11(9-19-14(12)16)10-3-4-17-13(8-10)20-15-18-5-6-24-15;1-10-14(9-22(3,20)21)6-13(8-17-10)12-4-5-16-15(7-12)18-11(2)19/h3-11H,12H2,1-2H3,(H,25,27,28);2-5,7-10,25H,6H2,1H3,(H2,22,24);4-8,12H,2-3H2,1H3,(H2,17,19)(H,21,23)(H,18,20,22);3-9H,1-2H3,(H2,16,19)(H,17,18,20);4-8H,9H2,1-3H3,(H,16,18,19).
What are the key properties of 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide?
5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide has a molecular weight of 1859.01 g/mol, XLogP of 12.58, 24 rotatable bonds, 9 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(2-acetamido-4-pyridinyl)-2-amino-N-cyclopropylpyridine-3-carboxamide;2-amino-N-(2,4-difluorophenyl)-5-[2-(2-oxopropyl)-4-pyridinyl]pyridine-3-sulfonamide;2-amino-N,N-dimethyl-5-[2-(1,3-oxazol-2-ylamino)-4-pyridinyl]pyridine-3-sulfonamide;N-[4-[6-methyl-5-(methylsulfonylmethyl)-3-pyridinyl]-2-pyridinyl]acetamide;N-[4-[6-methyl-5-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]-3-pyridinyl]-2-pyridinyl]acetamide is sourced from PubChem (CID 158424458), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).