7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine

C152H181F16N29O4 — CID 158460124

About 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine

7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine (PubChem CID 158460124) has the molecular formula C152H181F16N29O4 and a molecular weight of 2782.29 g/mol. Its IUPAC name is 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine.

Molecular Properties

• Compound Name: 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine
• PubChem CID: 158460124
• Molecular Formula: C152H181F16N29O4
• Molecular Weight: 2782.29 g/mol
• Exact Mass: 2780.46
• IUPAC Name: 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine
• SMILES: Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(C(F)(F)F)c(N4CC(C)(N(C)C)C4)cc23)c1C.Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(C(F)(F)F)c(N4CC(C)(O)C4)cc23)c1C.Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(C(F)(F)F)c(N4CCOCC4)cc23)c1C.Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(F)c(N4CCN(C)CC4)cc23)c1C.Cc1nnc(N[C@H](C)c2cccc(C(F)(F)C(C)(C)C)c2F)c2cc(N3CCN4CCOC[C@@H]4C3)ncc12.Cc1nnc(N[C@H](C)c2cccc(C(F)(F)C(C)(C)C)c2F)c2cc(N3C[C@H]4C[C@@H]3CO4)ncc12
• InChI: InChI=1S/C28H35F3N6O.C26H30F3N5O.C26H32F3N5.2C24H27F3N4O.C24H30FN5/c1-17(20-7-6-8-23(25(20)29)28(30,31)27(3,4)5)33-26-21-13-24(32-14-22(21)18(2)34-35-26)37-10-9-36-11-12-38-16-19(36)15-37;1-14(18-7-6-8-21(23(18)27)26(28,29)25(3,4)5)31-24-19-10-22(30-11-20(19)15(2)32-33-24)34-12-17-9-16(34)13-35-17;1-15-9-8-10-19(16(15)2)17(3)30-24-21-12-23(34-13-25(5,14-34)33(6)7)22(26(27,28)29)11-20(21)18(4)31-32-24;1-13-7-6-8-17(14(13)2)15(3)28-22-19-10-21(31-11-23(5,32)12-31)20(24(25,26)27)9-18(19)16(4)29-30-22;1-14-6-5-7-18(15(14)2)16(3)28-23-20-13-22(31-8-10-32-11-9-31)21(24(25,26)27)12-19(20)17(4)29-30-23;1-15-7-6-8-19(16(15)2)17(3)26-24-21-14-23(30-11-9-29(5)10-12-30)22(25)13-20(21)18(4)27-28-24/h6-8,13-14,17,19H,9-12,15-16H2,1-5H3,(H,33,35);6-8,10-11,14,16-17H,9,12-13H2,1-5H3,(H,31,33);8-12,17H,13-14H2,1-7H3,(H,30,32);6-10,15,32H,11-12H2,1-5H3,(H,28,30);5-7,12-13,16H,8-11H2,1-4H3,(H,28,30);6-8,13-14,17H,9-12H2,1-5H3,(H,26,28)/t17-,19+;14-,16-,17-;17-;15-;16-;17-/m111111/s1
• InChIKey: HFBJAXHFNFHLMB-XHNUALBRSA-N
• XLogP: 32.47
• TPSA: 329.72 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 33
• Rotatable Bonds: 27
• Heavy Atoms: 201
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2782.29
LogP ≤ 5	32.47
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine?

The IUPAC name of 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine (CID 158460124) is 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine.

What is the SMILES notation for 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine?

The canonical SMILES for 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine is Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(C(F)(F)F)c(N4CC(C)(N(C)C)C4)cc23)c1C.Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(C(F)(F)F)c(N4CC(C)(O)C4)cc23)c1C.Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(C(F)(F)F)c(N4CCOCC4)cc23)c1C.Cc1cccc([C@@H](C)Nc2nnc(C)c3cc(F)c(N4CCN(C)CC4)cc23)c1C.Cc1nnc(N[C@H](C)c2cccc(C(F)(F)C(C)(C)C)c2F)c2cc(N3CCN4CCOC[C@@H]4C3)ncc12.Cc1nnc(N[C@H](C)c2cccc(C(F)(F)C(C)(C)C)c2F)c2cc(N3C[C@H]4C[C@@H]3CO4)ncc12.

What is the InChIKey of 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine?

The InChIKey is HFBJAXHFNFHLMB-XHNUALBRSA-N. The full InChI is InChI=1S/C28H35F3N6O.C26H30F3N5O.C26H32F3N5.2C24H27F3N4O.C24H30FN5/c1-17(20-7-6-8-23(25(20)29)28(30,31)27(3,4)5)33-26-21-13-24(32-14-22(21)18(2)34-35-26)37-10-9-36-11-12-38-16-19(36)15-37;1-14(18-7-6-8-21(23(18)27)26(28,29)25(3,4)5)31-24-19-10-22(30-11-20(19)15(2)32-33-24)34-12-17-9-16(34)13-35-17;1-15-9-8-10-19(16(15)2)17(3)30-24-21-12-23(34-13-25(5,14-34)33(6)7)22(26(27,28)29)11-20(21)18(4)31-32-24;1-13-7-6-8-17(14(13)2)15(3)28-22-19-10-21(31-11-23(5,32)12-31)20(24(25,26)27)9-18(19)16(4)29-30-22;1-14-6-5-7-18(15(14)2)16(3)28-23-20-13-22(31-8-10-32-11-9-31)21(24(25,26)27)12-19(20)17(4)29-30-23;1-15-7-6-8-19(16(15)2)17(3)26-24-21-14-23(30-11-9-29(5)10-12-30)22(25)13-20(21)18(4)27-28-24/h6-8,13-14,17,19H,9-12,15-16H2,1-5H3,(H,33,35);6-8,10-11,14,16-17H,9,12-13H2,1-5H3,(H,31,33);8-12,17H,13-14H2,1-7H3,(H,30,32);6-10,15,32H,11-12H2,1-5H3,(H,28,30);5-7,12-13,16H,8-11H2,1-4H3,(H,28,30);6-8,13-14,17H,9-12H2,1-5H3,(H,26,28)/t17-,19+;14-,16-,17-;17-;15-;16-;17-/m111111/s1.

What are the key properties of 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine?

7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine has a molecular weight of 2782.29 g/mol, XLogP of 32.47, 27 rotatable bonds, 7 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 7-[(9aS)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methylpyrido[3,4-d]pyridazin-1-amine;N-[(1R)-1-[3-(1,1-difluoro-2,2-dimethylpropyl)-2-fluorophenyl]ethyl]-4-methyl-7-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrido[3,4-d]pyridazin-1-amine;7-[3-(dimethylamino)-3-methylazetidin-1-yl]-N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-6-(trifluoromethyl)phthalazin-1-amine;1-[4-[[(1R)-1-(2,3-dimethylphenyl)ethyl]amino]-1-methyl-7-(trifluoromethyl)phthalazin-6-yl]-3-methylazetidin-3-ol;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-6-fluoro-4-methyl-7-(4-methylpiperazin-1-yl)phthalazin-1-amine;N-[(1R)-1-(2,3-dimethylphenyl)ethyl]-4-methyl-7-morpholin-4-yl-6-(trifluoromethyl)phthalazin-1-amine is sourced from PubChem (CID 158460124), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).