8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine

C100H66Cl2F11N25 — CID 158465021

About 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine

8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine (PubChem CID 158465021) has the molecular formula C100H66Cl2F11N25 and a molecular weight of 1897.69 g/mol. Its IUPAC name is 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine.

Molecular Properties

• Compound Name: 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine
• PubChem CID: 158465021
• Molecular Formula: C100H66Cl2F11N25
• Molecular Weight: 1897.69 g/mol
• Exact Mass: 1895.51
• IUPAC Name: 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine
• SMILES: Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccnc23)cc(C(F)(F)F)n1.Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccnc23)cc(C)n1.Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccnc23)cc(Cl)n1.Nc1nc(-c2ccc(F)cc2)c(-c2cc(Cl)nc(C(F)(F)F)c2)c2nccnc12.Nc1nc(-c2ccc(F)cc2)c(-c2ccc3ncccc3c2)c2nccnc12
• InChI: InChI=1S/C22H14FN5.C20H13F4N5.C20H16FN5.C19H10ClF4N5.C19H13ClFN5/c23-16-6-3-13(4-7-16)19-18(20-21(22(24)28-19)27-11-10-26-20)15-5-8-17-14(12-15)2-1-9-25-17;1-10-8-12(9-14(28-10)20(22,23)24)15-16(11-2-4-13(21)5-3-11)29-19(25)18-17(15)26-6-7-27-18;1-11-9-14(10-12(2)25-11)16-17(13-3-5-15(21)6-4-13)26-20(22)19-18(16)23-7-8-24-19;20-13-8-10(7-12(28-13)19(22,23)24)14-15(9-1-3-11(21)4-2-9)29-18(25)17-16(14)26-5-6-27-17;1-10-8-12(9-14(20)25-10)15-16(11-2-4-13(21)5-3-11)26-19(22)18-17(15)23-6-7-24-18/h1-12H,(H2,24,28);2-9H,1H3,(H2,25,29);3-10H,1-2H3,(H2,22,26);1-8H,(H2,25,29);2-9H,1H3,(H2,22,26)
• InChIKey: HFQNDOXCFFMMRH-UHFFFAOYSA-N
• XLogP: 23.11
• TPSA: 387.90 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 25
• Rotatable Bonds: 10
• Heavy Atoms: 138
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1897.69
LogP ≤ 5	23.11
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	25

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine?

The IUPAC name of 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine (CID 158465021) is 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine.

What is the SMILES notation for 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine?

The canonical SMILES for 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine is Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccnc23)cc(C(F)(F)F)n1.Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccnc23)cc(C)n1.Cc1cc(-c2c(-c3ccc(F)cc3)nc(N)c3nccnc23)cc(Cl)n1.Nc1nc(-c2ccc(F)cc2)c(-c2cc(Cl)nc(C(F)(F)F)c2)c2nccnc12.Nc1nc(-c2ccc(F)cc2)c(-c2ccc3ncccc3c2)c2nccnc12.

What is the InChIKey of 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine?

The InChIKey is HFQNDOXCFFMMRH-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H14FN5.C20H13F4N5.C20H16FN5.C19H10ClF4N5.C19H13ClFN5/c23-16-6-3-13(4-7-16)19-18(20-21(22(24)28-19)27-11-10-26-20)15-5-8-17-14(12-15)2-1-9-25-17;1-10-8-12(9-14(28-10)20(22,23)24)15-16(11-2-4-13(21)5-3-11)29-19(25)18-17(15)26-6-7-27-18;1-11-9-14(10-12(2)25-11)16-17(13-3-5-15(21)6-4-13)26-20(22)19-18(16)23-7-8-24-19;20-13-8-10(7-12(28-13)19(22,23)24)14-15(9-1-3-11(21)4-2-9)29-18(25)17-16(14)26-5-6-27-17;1-10-8-12(9-14(20)25-10)15-16(11-2-4-13(21)5-3-11)26-19(22)18-17(15)23-6-7-24-18/h1-12H,(H2,24,28);2-9H,1H3,(H2,25,29);3-10H,1-2H3,(H2,22,26);1-8H,(H2,25,29);2-9H,1H3,(H2,22,26).

What are the key properties of 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine?

8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine has a molecular weight of 1897.69 g/mol, XLogP of 23.11, 10 rotatable bonds, 5 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(2-chloro-6-methyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-[2-chloro-6-(trifluoromethyl)-4-pyridinyl]-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;8-(2,6-dimethyl-4-pyridinyl)-7-(4-fluorophenyl)pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-[2-methyl-6-(trifluoromethyl)-4-pyridinyl]pyrido[3,4-b]pyrazin-5-amine;7-(4-fluorophenyl)-8-quinolin-6-ylpyrido[3,4-b]pyrazin-5-amine is sourced from PubChem (CID 158465021), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).