4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile

C148H164N28O12 — CID 158466555

About 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile

4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile (PubChem CID 158466555) has the molecular formula C148H164N28O12 and a molecular weight of 2527.12 g/mol. Its IUPAC name is 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile.

Molecular Properties

• Compound Name: 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile
• PubChem CID: 158466555
• Molecular Formula: C148H164N28O12
• Molecular Weight: 2527.12 g/mol
• Exact Mass: 2525.31
• IUPAC Name: 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile
• SMILES: COc1ccc(-c2cnn3cccc(C4CCC(C#N)CC4)c23)cc1.Cn1ncc2cc(-c3cnn4ccnc(C5=CCC(C(N)=O)CC5)c34)ccc21.N#CC1CC=C(c2cccn3ncc(-c4ccc(OCC(O)CN5CCCCC5)cc4)c23)CC1.N#CC1CC=C(c2nccn3ncc(-c4ccc(OCCCN5CCOCC5)cc4)c23)CC1.NC(=O)C1CC=C(c2nccn3ncc(-c4ccc(OCCN5CCOCC5)cc4)c23)CC1.O=C1NCCC12CCN(c1cccn3ncc(-c4ccc(OCCN5CCOCC5)cc4)c13)CC2
• InChI: InChI=1S/C28H32N4O2.C27H33N5O3.C26H29N5O2.C25H29N5O3.C21H20N6O.C21H21N3O/c29-17-21-6-8-22(9-7-21)26-5-4-16-32-28(26)27(18-30-32)23-10-12-25(13-11-23)34-20-24(33)19-31-14-2-1-3-15-31;33-26-27(7-10-28-26)8-12-31(13-9-27)24-2-1-11-32-25(24)23(20-29-32)21-3-5-22(6-4-21)35-19-16-30-14-17-34-18-15-30;27-18-20-2-4-22(5-3-20)25-26-24(19-29-31(26)12-10-28-25)21-6-8-23(9-7-21)33-15-1-11-30-13-16-32-17-14-30;26-25(31)20-3-1-19(2-4-20)23-24-22(17-28-30(24)10-9-27-23)18-5-7-21(8-6-18)33-16-13-29-11-14-32-15-12-29;1-26-18-7-6-15(10-16(18)11-24-26)17-12-25-27-9-8-23-19(20(17)27)13-2-4-14(5-3-13)21(22)28;1-25-18-10-8-17(9-11-18)20-14-23-24-12-2-3-19(21(20)24)16-6-4-15(13-22)5-7-16/h4-5,8,10-13,16,18,21,24,33H,1-3,6-7,9,14-15,19-20H2;1-6,11,20H,7-10,12-19H2,(H,28,33);4,6-10,12,19-20H,1-3,5,11,13-17H2;1,5-10,17,20H,2-4,11-16H2,(H2,26,31);2,6-12,14H,3-5H2,1H3,(H2,22,28);2-3,8-12,14-16H,4-7H2,1H3
• InChIKey: HFVADPQABYGSAX-UHFFFAOYSA-N
• XLogP: 22.49
• TPSA: 457.21 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 37
• Rotatable Bonds: 33
• Heavy Atoms: 188
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2527.12
LogP ≤ 5	22.49
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	37

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile?

The IUPAC name of 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile (CID 158466555) is 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile.

What is the SMILES notation for 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile?

The canonical SMILES for 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile is COc1ccc(-c2cnn3cccc(C4CCC(C#N)CC4)c23)cc1.Cn1ncc2cc(-c3cnn4ccnc(C5=CCC(C(N)=O)CC5)c34)ccc21.N#CC1CC=C(c2cccn3ncc(-c4ccc(OCC(O)CN5CCCCC5)cc4)c23)CC1.N#CC1CC=C(c2nccn3ncc(-c4ccc(OCCCN5CCOCC5)cc4)c23)CC1.NC(=O)C1CC=C(c2nccn3ncc(-c4ccc(OCCN5CCOCC5)cc4)c23)CC1.O=C1NCCC12CCN(c1cccn3ncc(-c4ccc(OCCN5CCOCC5)cc4)c13)CC2.

What is the InChIKey of 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile?

The InChIKey is HFVADPQABYGSAX-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H32N4O2.C27H33N5O3.C26H29N5O2.C25H29N5O3.C21H20N6O.C21H21N3O/c29-17-21-6-8-22(9-7-21)26-5-4-16-32-28(26)27(18-30-32)23-10-12-25(13-11-23)34-20-24(33)19-31-14-2-1-3-15-31;33-26-27(7-10-28-26)8-12-31(13-9-27)24-2-1-11-32-25(24)23(20-29-32)21-3-5-22(6-4-21)35-19-16-30-14-17-34-18-15-30;27-18-20-2-4-22(5-3-20)25-26-24(19-29-31(26)12-10-28-25)21-6-8-23(9-7-21)33-15-1-11-30-13-16-32-17-14-30;26-25(31)20-3-1-19(2-4-20)23-24-22(17-28-30(24)10-9-27-23)18-5-7-21(8-6-18)33-16-13-29-11-14-32-15-12-29;1-26-18-7-6-15(10-16(18)11-24-26)17-12-25-27-9-8-23-19(20(17)27)13-2-4-14(5-3-13)21(22)28;1-25-18-10-8-17(9-11-18)20-14-23-24-12-2-3-19(21(20)24)16-6-4-15(13-22)5-7-16/h4-5,8,10-13,16,18,21,24,33H,1-3,6-7,9,14-15,19-20H2;1-6,11,20H,7-10,12-19H2,(H,28,33);4,6-10,12,19-20H,1-3,5,11,13-17H2;1,5-10,17,20H,2-4,11-16H2,(H2,26,31);2,6-12,14H,3-5H2,1H3,(H2,22,28);2-3,8-12,14-16H,4-7H2,1H3.

What are the key properties of 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile?

4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile has a molecular weight of 2527.12 g/mol, XLogP of 22.49, 33 rotatable bonds, 4 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[3-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]cyclohexane-1-carbonitrile;4-[3-(1-methylindazol-5-yl)pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;4-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carboxamide;8-[3-[4-(2-morpholin-4-ylethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one;4-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrazolo[1,5-a]pyrazin-4-yl]cyclohex-3-ene-1-carbonitrile is sourced from PubChem (CID 158466555), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).