N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide

C118H101ClF9N19O9 — CID 158480142

About N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide

N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide (PubChem CID 158480142) has the molecular formula C118H101ClF9N19O9 and a molecular weight of 2135.66 g/mol. Its IUPAC name is N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide.

Molecular Properties

• Compound Name: N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide
• PubChem CID: 158480142
• Molecular Formula: C118H101ClF9N19O9
• Molecular Weight: 2135.66 g/mol
• Exact Mass: 2133.76
• IUPAC Name: N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide
• SMILES: COc1ccc(-c2ccc(NC(=O)c3ccc(C)cc3)nc2N)c(C(F)(F)F)c1.COc1ccc(F)cc1-c1ccc(NC(=O)c2ccc(C)cc2)nc1N.Cc1ccc(C(=O)Nc2ccc(-c3cc(C)c(F)cc3C)c(N)n2)cc1.Cc1ccc(C(=O)Nc2ccc(-c3cc(F)ccc3F)c(N)n2)cc1.Cc1ccc(C(=O)Nc2ccc(-c3cc(O)ccc3Cl)c(N)n2)cc1.Cc1ccc(C(=O)Nc2ccc(-c3ccc(F)nc3F)c(N)n2)cc1
• InChI: InChI=1S/C21H18F3N3O2.C21H20FN3O.C20H18FN3O2.C19H16ClN3O2.C19H15F2N3O.C18H14F2N4O/c1-12-3-5-13(6-4-12)20(28)27-18-10-9-16(19(25)26-18)15-8-7-14(29-2)11-17(15)21(22,23)24;1-12-4-6-15(7-5-12)21(26)25-19-9-8-16(20(23)24-19)17-10-14(3)18(22)11-13(17)2;1-12-3-5-13(6-4-12)20(25)24-18-10-8-15(19(22)23-18)16-11-14(21)7-9-17(16)26-2;1-11-2-4-12(5-3-11)19(25)23-17-9-7-14(18(21)22-17)15-10-13(24)6-8-16(15)20;1-11-2-4-12(5-3-11)19(25)24-17-9-7-14(18(22)23-17)15-10-13(20)6-8-16(15)21;1-10-2-4-11(5-3-10)18(25)24-15-9-7-13(17(21)23-15)12-6-8-14(19)22-16(12)20/h3-11H,1-2H3,(H3,25,26,27,28);4-11H,1-3H3,(H3,23,24,25,26);3-11H,1-2H3,(H3,22,23,24,25);2-10,24H,1H3,(H3,21,22,23,25);2-10H,1H3,(H3,22,23,24,25);2-9H,1H3,(H3,21,23,24,25)
• InChIKey: HHKQZQPFJPOCHO-UHFFFAOYSA-N
• XLogP: 25.59
• TPSA: 459.64 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 22
• Rotatable Bonds: 20
• Heavy Atoms: 156
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2135.66
LogP ≤ 5	25.59
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	22

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide?

The IUPAC name of N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide (CID 158480142) is N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide.

What is the SMILES notation for N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide?

The canonical SMILES for N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide is COc1ccc(-c2ccc(NC(=O)c3ccc(C)cc3)nc2N)c(C(F)(F)F)c1.COc1ccc(F)cc1-c1ccc(NC(=O)c2ccc(C)cc2)nc1N.Cc1ccc(C(=O)Nc2ccc(-c3cc(C)c(F)cc3C)c(N)n2)cc1.Cc1ccc(C(=O)Nc2ccc(-c3cc(F)ccc3F)c(N)n2)cc1.Cc1ccc(C(=O)Nc2ccc(-c3cc(O)ccc3Cl)c(N)n2)cc1.Cc1ccc(C(=O)Nc2ccc(-c3ccc(F)nc3F)c(N)n2)cc1.

What is the InChIKey of N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide?

The InChIKey is HHKQZQPFJPOCHO-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H18F3N3O2.C21H20FN3O.C20H18FN3O2.C19H16ClN3O2.C19H15F2N3O.C18H14F2N4O/c1-12-3-5-13(6-4-12)20(28)27-18-10-9-16(19(25)26-18)15-8-7-14(29-2)11-17(15)21(22,23)24;1-12-4-6-15(7-5-12)21(26)25-19-9-8-16(20(23)24-19)17-10-14(3)18(22)11-13(17)2;1-12-3-5-13(6-4-12)20(25)24-18-10-8-15(19(22)23-18)16-11-14(21)7-9-17(16)26-2;1-11-2-4-12(5-3-11)19(25)23-17-9-7-14(18(21)22-17)15-10-13(24)6-8-16(15)20;1-11-2-4-12(5-3-11)19(25)24-17-9-7-14(18(22)23-17)15-10-13(20)6-8-16(15)21;1-10-2-4-11(5-3-10)18(25)24-15-9-7-13(17(21)23-15)12-6-8-14(19)22-16(12)20/h3-11H,1-2H3,(H3,25,26,27,28);4-11H,1-3H3,(H3,23,24,25,26);3-11H,1-2H3,(H3,22,23,24,25);2-10,24H,1H3,(H3,21,22,23,25);2-10H,1H3,(H3,22,23,24,25);2-9H,1H3,(H3,21,23,24,25).

What are the key properties of N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide?

N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide has a molecular weight of 2135.66 g/mol, XLogP of 25.59, 20 rotatable bonds, 13 hydrogen bond donors, and 22 hydrogen bond acceptors.

Where does this data come from?

All data for N-[6-amino-5-(2-chloro-5-hydroxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,5-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(2,6-difluoro-3-pyridinyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-fluoro-2,5-dimethylphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(5-fluoro-2-methoxyphenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[4-methoxy-2-(trifluoromethyl)phenyl]-2-pyridinyl]-4-methylbenzamide is sourced from PubChem (CID 158480142), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).