5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane

C130H146F23N25O3 — CID 158481243

IUPAC5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane
SMILESCc1ncc(-c2cn(C3CC(F)(F)C3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CC4(C3)CN(C3COC3)C4)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CCCC3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CN(C4COC4)C3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3COC3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(Cc3ccccn3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(Cc3cccnc3)c(C(C)C)n2)cc1C(F)(F)F
InChIInChI=1S/C22H27F3N4O.C19H23F3N4O.2C19H19F3N4.C18H22F3N3.C17H18F5N3.C16H18F3N3O/c1-13(2)20-27-19(15-4-18(22(23,24)25)14(3)26-7-15)8-29(20)16-5-21(6-16)11-28(12-21)17-9-30-10-17;1-11(2)18-24-17(13-4-16(19(20,21)22)12(3)23-5-13)8-26(18)14-6-25(7-14)15-9-27-10-15;1-12(2)18-25-17(11-26(18)10-14-5-4-6-23-8-14)15-7-16(19(20,21)22)13(3)24-9-15;1-12(2)18-25-17(11-26(18)10-15-6-4-5-7-23-15)14-8-16(19(20,21)22)13(3)24-9-14;1-11(2)17-23-16(10-24(17)14-6-4-5-7-14)13-8-15(18(19,20)21)12(3)22-9-13;1-9(2)15-24-14(8-25(15)12-5-16(18,19)6-12)11-4-13(17(20,21)22)10(3)23-7-11;1-9(2)15-21-14(6-22(15)12-7-23-8-12)11-4-13(16(17,18)19)10(3)20-5-11/h4,7-8,13,16-17H,5-6,9-12H2,1-3H3;4-5,8,11,14-15H,6-7,9-10H2,1-3H3;2*4-9,11-12H,10H2,1-3H3;8-11,14H,4-7H2,1-3H3;4,7-9,12H,5-6H2,1-3H3;4-6,9,12H,7-8H2,1-3H3
InChIKeyHHNUBFQZFZNYEY-UHFFFAOYSA-N
MW2543.72 g/mol
LogP32.60
Rot. Bonds25

About 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane

5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane (PubChem CID 158481243) has the molecular formula C130H146F23N25O3 and a molecular weight of 2543.72 g/mol. Its IUPAC name is 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane.

Molecular Properties

Compound Name5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane
PubChem CID158481243
Molecular FormulaC130H146F23N25O3
Molecular Weight2543.72 g/mol
Exact Mass2542.17
IUPAC Name5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane
SMILESCc1ncc(-c2cn(C3CC(F)(F)C3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CC4(C3)CN(C3COC3)C4)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CCCC3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CN(C4COC4)C3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3COC3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(Cc3ccccn3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(Cc3cccnc3)c(C(C)C)n2)cc1C(F)(F)F
InChIInChI=1S/C22H27F3N4O.C19H23F3N4O.2C19H19F3N4.C18H22F3N3.C17H18F5N3.C16H18F3N3O/c1-13(2)20-27-19(15-4-18(22(23,24)25)14(3)26-7-15)8-29(20)16-5-21(6-16)11-28(12-21)17-9-30-10-17;1-11(2)18-24-17(13-4-16(19(20,21)22)12(3)23-5-13)8-26(18)14-6-25(7-14)15-9-27-10-15;1-12(2)18-25-17(11-26(18)10-14-5-4-6-23-8-14)15-7-16(19(20,21)22)13(3)24-9-15;1-12(2)18-25-17(11-26(18)10-15-6-4-5-7-23-15)14-8-16(19(20,21)22)13(3)24-9-14;1-11(2)17-23-16(10-24(17)14-6-4-5-7-14)13-8-15(18(19,20)21)12(3)22-9-13;1-9(2)15-24-14(8-25(15)12-5-16(18,19)6-12)11-4-13(17(20,21)22)10(3)23-7-11;1-9(2)15-21-14(6-22(15)12-7-23-8-12)11-4-13(16(17,18)19)10(3)20-5-11/h4,7-8,13,16-17H,5-6,9-12H2,1-3H3;4-5,8,11,14-15H,6-7,9-10H2,1-3H3;2*4-9,11-12H,10H2,1-3H3;8-11,14H,4-7H2,1-3H3;4,7-9,12H,5-6H2,1-3H3;4-6,9,12H,7-8H2,1-3H3
InChIKeyHHNUBFQZFZNYEY-UHFFFAOYSA-N
XLogP32.60
TPSA274.92 Ų
H-Bond Donors
H-Bond Acceptors28
Rotatable Bonds25
Heavy Atoms181
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002543.72
LogP ≤ 532.60
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1028

Analyze 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane with MolForge

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Launch Full Analysis

Related Compounds

2-(3,3-difluoroazetidin-1-yl)-N-[6-[5-[[3-[2-(3,3-difluoroazetidin-1-yl)-6-[[6-[4-[[3-[2-(3,3-difluoroazetidin-1-yl)-6-[[4-(trifluoromethyl)-2-pyridinyl]amino]pyrimidin-4-yl]pyrrolidin-1-yl]methyl]imidazol-1-yl]-4-(trifluoromethyl)-2-pyridinyl]amino]pyrimidin-4-yl]pyrrolidin-1-yl]methyl]pyrimidin-2-yl]-4-(trifluoromethyl)-2-pyridinyl]-6-[1-(oxolan-3-ylmethyl)pyrrolidin-3-yl]pyrimidin-4-amine
CID 123895331
3-methyl-1-[5-[[7-[4-[1-(1-methylazetidin-3-yl)-4-(trifluoromethyl)imidazol-2-yl]phenyl]-1-(2-propan-2-yl-3-pyridinyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl]methyl]-2-propan-2-yl-3-pyridinyl]-7-[6-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]-3-pyridinyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine
CID 153629346
5-[2-Cyclobutyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;5-[2-cyclopentyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;5-[2-ethyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;bis(3-methyl-5-[2-(2-methylpropyl)-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]pyridin-2-amine);4-[3-[2-(2-methylpropyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]morpholine
CID 157320784
1-[4-(6-Amino-5-methyl-3-pyridinyl)-1-(1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]ethanol;bis(5-[2-(cyclopropylmethyl)-1-[3-(4-methylpiperazin-1-yl)-1-bicyclo[1.1.1]pentanyl]imidazol-4-yl]-3-methylpyridin-2-amine);bis(5-[2-cyclopropyl-1-[3-(4-methylpiperazin-1-yl)-1-bicyclo[1.1.1]pentanyl]imidazol-4-yl]-3-methylpyridin-2-amine);1-[3-[2-cyclopropyl-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]-4-methylpiperazine;3-methyl-5-[1-[3-(4-methylpiperazin-1-yl)-1-bicyclo[1.1.1]pentanyl]-2-propan-2-ylimidazol-4-yl]pyridin-2-amine
CID 157428003
9-[[3,5-Difluoro-4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7-methyl-2-(2-propan-2-yl-3-pyridinyl)purin-8-one;9-[[3-fluoro-4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7-methyl-2-(2-propan-2-yl-3-pyridinyl)purin-8-one;methane;7-methyl-9-[[4-[1-(oxetan-3-yl)-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-(2-propan-2-yl-3-pyridinyl)purin-8-one
CID 157615684
1-[4-(6-Amino-5-methyl-3-pyridinyl)-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]cyclopropane-1-carbonitrile;4-[3-[2-cyclopropyl-4-(5,6-dimethyl-3-pyridinyl)imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]morpholine;5-[2-cyclopropyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;3-methyl-5-[1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)-2-(oxolan-3-yl)imidazol-4-yl]pyridin-2-amine;3-methyl-5-[1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)-2-propan-2-ylimidazol-4-yl]pyridin-2-amine;4-[3-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]morpholine
CID 157716164
1-[(1R,5S)-6-[4-(6-amino-5-methyl-3-pyridinyl)-2-(cyclopropylmethyl)imidazol-1-yl]-3-azabicyclo[3.1.0]hexan-3-yl]ethanone;1-[(1S,5R)-6-[2-(cyclopropylmethyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-azabicyclo[3.1.0]hexan-3-yl]ethanone;tris(5-[1-[(1R,5S)-3-ethyl-3-azabicyclo[3.1.0]hexan-6-yl]-2-propan-2-ylimidazol-4-yl]-3-methylpyridin-2-amine);5-[1-[(1S,5R)-3-(2-fluoroethyl)-3-azabicyclo[3.1.0]hexan-6-yl]-2-propan-2-ylimidazol-4-yl]-3-methylpyridin-2-amine;5-[1-[(1R,5S)-3-(2-methoxyethyl)-3-azabicyclo[3.1.0]hexan-6-yl]-2-propan-2-ylimidazol-4-yl]-3-methylpyridin-2-amine
CID 157766882
2-Tert-butyl-8-(2,6-dimethyl-4-pyridinyl)-2,8-diazaspiro[4.5]decane;3-tert-butyl-9-imidazol-1-yl-3-azaspiro[5.5]undecane;3-tert-butyl-9-(2-imidazol-1-ylethoxy)-3-azaspiro[5.5]undecane;2-tert-butyl-8-(2-methyl-4-pyridinyl)-2,8-diazaspiro[4.5]decane;2-tert-butyl-8-pyridin-3-yl-2-azaspiro[4.5]decane;2-tert-butyl-8-[5-(trifluoromethyl)pyrimidin-2-yl]-2,8-diazaspiro[4.5]decane
CID 158051580
(1R,5S)-3-ethyl-6-[2-ethyl-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-azabicyclo[3.1.0]hexane;(1R,5S)-6-[2-ethyl-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-(2-fluoroethyl)-3-azabicyclo[3.1.0]hexane;(1R,5S)-3-(2-fluoroethyl)-6-[2-(2-methylpropyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-azabicyclo[3.1.0]hexane;(1R,5S)-3-(2-fluoroethyl)-6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-pentan-3-ylimidazol-1-yl]-3-azabicyclo[3.1.0]hexane;tris(4-[(1S,5R)-6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-3-bicyclo[3.1.0]hexanyl]morpholine)
CID 158051648
4-[3-[2-Butan-2-yl-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]morpholine;bis(5-[2-butan-2-yl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine);5-[2-ethyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;4-[3-[4-[5-(fluoromethyl)-6-methyl-3-pyridinyl]-2-(2-methylpropyl)imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]morpholine;bis(3-methyl-5-[2-(2-methylpropyl)-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]pyridin-2-amine)
CID 158119460
5-[2-Cyclobutyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;5-[2-cyclopentyl-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine;1-[3-[2-(cyclopropylmethyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]-4-methylpiperazine;4-[3-[2-(2,2-dimethylpropyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-1-bicyclo[1.1.1]pentanyl]morpholine;bis(5-[2-(2,2-dimethylpropyl)-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-4-yl]-3-methylpyridin-2-amine);3-methyl-5-[1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)-2-propan-2-ylimidazol-4-yl]pyridin-2-amine
CID 158267630
(1R,5S)-6-[2-(cyclopropylmethyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-ethyl-3-azabicyclo[3.1.0]hexane;(1S,5R)-6-[2-(cyclopropylmethyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-(2-fluoroethyl)-3-azabicyclo[3.1.0]hexane;(1R,5S)-6-[2-(cyclopropylmethyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-(2-methoxyethyl)-3-azabicyclo[3.1.0]hexane;(1R,5S)-6-[2-(cyclopropylmethyl)-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-(oxan-4-yl)-3-azabicyclo[3.1.0]hexane;(1R,5S)-6-[2-cyclopropyl-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-ethyl-3-azabicyclo[3.1.0]hexane;(1R,5S)-6-[2-cyclopropyl-4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]imidazol-1-yl]-3-(oxan-4-yl)-3-azabicyclo[3.1.0]hexane;3-methyl-5-[1-[(1R,5S)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-2-propan-2-ylimidazol-4-yl]pyridin-2-amine
CID 158377317

Frequently Asked Questions

What is the IUPAC name of 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane?
The IUPAC name of 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane (CID 158481243) is 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane.
What is the SMILES notation for 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane?
The canonical SMILES for 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane is Cc1ncc(-c2cn(C3CC(F)(F)C3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CC4(C3)CN(C3COC3)C4)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CCCC3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3CN(C4COC4)C3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(C3COC3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(Cc3ccccn3)c(C(C)C)n2)cc1C(F)(F)F.Cc1ncc(-c2cn(Cc3cccnc3)c(C(C)C)n2)cc1C(F)(F)F.
What is the InChIKey of 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane?
The InChIKey is HHNUBFQZFZNYEY-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H27F3N4O.C19H23F3N4O.2C19H19F3N4.C18H22F3N3.C17H18F5N3.C16H18F3N3O/c1-13(2)20-27-19(15-4-18(22(23,24)25)14(3)26-7-15)8-29(20)16-5-21(6-16)11-28(12-21)17-9-30-10-17;1-11(2)18-24-17(13-4-16(19(20,21)22)12(3)23-5-13)8-26(18)14-6-25(7-14)15-9-27-10-15;1-12(2)18-25-17(11-26(18)10-14-5-4-6-23-8-14)15-7-16(19(20,21)22)13(3)24-9-15;1-12(2)18-25-17(11-26(18)10-15-6-4-5-7-23-15)14-8-16(19(20,21)22)13(3)24-9-14;1-11(2)17-23-16(10-24(17)14-6-4-5-7-14)13-8-15(18(19,20)21)12(3)22-9-13;1-9(2)15-24-14(8-25(15)12-5-16(18,19)6-12)11-4-13(17(20,21)22)10(3)23-7-11;1-9(2)15-21-14(6-22(15)12-7-23-8-12)11-4-13(16(17,18)19)10(3)20-5-11/h4,7-8,13,16-17H,5-6,9-12H2,1-3H3;4-5,8,11,14-15H,6-7,9-10H2,1-3H3;2*4-9,11-12H,10H2,1-3H3;8-11,14H,4-7H2,1-3H3;4,7-9,12H,5-6H2,1-3H3;4-6,9,12H,7-8H2,1-3H3.
What are the key properties of 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane?
5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane has a molecular weight of 2543.72 g/mol, XLogP of 32.60, 25 rotatable bonds, 0 hydrogen bond donors, and 28 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(1-cyclopentyl-2-propan-2-ylimidazol-4-yl)-2-methyl-3-(trifluoromethyl)pyridine;5-[1-(3,3-difluorocyclobutyl)-2-propan-2-ylimidazol-4-yl]-2-methyl-3-(trifluoromethyl)pyridine;2-methyl-5-[1-[1-(oxetan-3-yl)azetidin-3-yl]-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[1-(oxetan-3-yl)-2-propan-2-ylimidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-2-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;2-methyl-5-[2-propan-2-yl-1-(pyridin-3-ylmethyl)imidazol-4-yl]-3-(trifluoromethyl)pyridine;6-[4-[6-methyl-5-(trifluoromethyl)-3-pyridinyl]-2-propan-2-ylimidazol-1-yl]-2-(oxetan-3-yl)-2-azaspiro[3.3]heptane is sourced from PubChem (CID 158481243), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).