3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride

C95H120BBrClN15O14 — CID 158482318

About 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride

3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride (PubChem CID 158482318) has the molecular formula C95H120BBrClN15O14 and a molecular weight of 1822.26 g/mol. Its IUPAC name is 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride.

Molecular Properties

• Compound Name: 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride
• PubChem CID: 158482318
• Molecular Formula: C95H120BBrClN15O14
• Molecular Weight: 1822.26 g/mol
• Exact Mass: 1819.81
• IUPAC Name: 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride
• SMILES: C1=C(c2ccc3[nH]nc(-c4cncc(O[C@H]5CNCCC56CC6)n4)c3c2)CCOC1.CC(C)(C)OC(=O)N1CCC2(CC2)[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(Br)cc34)n2)C1.CC(C)(C)OC(=O)N1CCC2(CC2)[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(C5=CCOCC5)cc34)n2)C1.CC1(C)OB(C2=CCOCC2)OC1(C)C.Cl
• InChI: InChI=1S/C33H41N5O5.C28H34BrN5O4.C23H25N5O2.C11H19BO3.ClH/c1-32(2,3)43-31(39)37-14-13-33(11-12-33)27(21-37)42-28-20-34-19-25(35-28)30-24-18-23(22-9-16-40-17-10-22)7-8-26(24)38(36-30)29-6-4-5-15-41-29;1-27(2,3)38-26(35)33-12-11-28(9-10-28)22(17-33)37-23-16-30-15-20(31-23)25-19-14-18(29)7-8-21(19)34(32-25)24-6-4-5-13-36-24;1-2-18-17(11-16(1)15-3-9-29-10-4-15)22(28-27-18)19-12-25-14-21(26-19)30-20-13-24-8-7-23(20)5-6-23;1-10(2)11(3,4)15-12(14-10)9-5-7-13-8-6-9;/h7-9,18-20,27,29H,4-6,10-17,21H2,1-3H3;7-8,14-16,22,24H,4-6,9-13,17H2,1-3H3;1-3,11-12,14,20,24H,4-10,13H2,(H,27,28);5H,6-8H2,1-4H3;1H/t27-,29?;22-,24?;20-;;/m000../s1
• InChIKey: QLKXHYFMSRBYLB-ZVCYMMCASA-N
• XLogP: 18.02
• TPSA: 305.07 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 26
• Rotatable Bonds: 14
• Heavy Atoms: 127
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1822.26
LogP ≤ 5	18.02
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride?

The IUPAC name of 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride (CID 158482318) is 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride.

What is the SMILES notation for 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride?

The canonical SMILES for 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride is C1=C(c2ccc3[nH]nc(-c4cncc(O[C@H]5CNCCC56CC6)n4)c3c2)CCOC1.CC(C)(C)OC(=O)N1CCC2(CC2)[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(Br)cc34)n2)C1.CC(C)(C)OC(=O)N1CCC2(CC2)[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(C5=CCOCC5)cc34)n2)C1.CC1(C)OB(C2=CCOCC2)OC1(C)C.Cl.

What is the InChIKey of 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride?

The InChIKey is QLKXHYFMSRBYLB-ZVCYMMCASA-N. The full InChI is InChI=1S/C33H41N5O5.C28H34BrN5O4.C23H25N5O2.C11H19BO3.ClH/c1-32(2,3)43-31(39)37-14-13-33(11-12-33)27(21-37)42-28-20-34-19-25(35-28)30-24-18-23(22-9-16-40-17-10-22)7-8-26(24)38(36-30)29-6-4-5-15-41-29;1-27(2,3)38-26(35)33-12-11-28(9-10-28)22(17-33)37-23-16-30-15-20(31-23)25-19-14-18(29)7-8-21(19)34(32-25)24-6-4-5-13-36-24;1-2-18-17(11-16(1)15-3-9-29-10-4-15)22(28-27-18)19-12-25-14-21(26-19)30-20-13-24-8-7-23(20)5-6-23;1-10(2)11(3,4)15-12(14-10)9-5-7-13-8-6-9;/h7-9,18-20,27,29H,4-6,10-17,21H2,1-3H3;7-8,14-16,22,24H,4-6,9-13,17H2,1-3H3;1-3,11-12,14,20,24H,4-10,13H2,(H,27,28);5H,6-8H2,1-4H3;1H/t27-,29?;22-,24?;20-;;/m000../s1.

What are the key properties of 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride?

3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride has a molecular weight of 1822.26 g/mol, XLogP of 18.02, 14 rotatable bonds, 2 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 3-[6-[[(8R)-6-azaspiro[2.5]octan-8-yl]oxy]pyrazin-2-yl]-5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole;tert-butyl (8R)-8-[6-[5-bromo-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;tert-butyl (8R)-8-[6-[5-(3,6-dihydro-2H-pyran-4-yl)-1-(oxan-2-yl)indazol-3-yl]pyrazin-2-yl]oxy-6-azaspiro[2.5]octane-6-carboxylate;2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;hydrochloride is sourced from PubChem (CID 158482318), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).