N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide

C163H124Cl6F23N19O8 — CID 158494190

About N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide

N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide (PubChem CID 158494190) has the molecular formula C163H124Cl6F23N19O8 and a molecular weight of 3126.58 g/mol. Its IUPAC name is N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide.

Molecular Properties

• Compound Name: N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide
• PubChem CID: 158494190
• Molecular Formula: C163H124Cl6F23N19O8
• Molecular Weight: 3126.58 g/mol
• Exact Mass: 3121.76
• IUPAC Name: N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide
• SMILES: CC(C)C(=O)Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1.Cc1cc2c(cc1-c1cnc(NC(=O)C(C)C)cn1)CC(F)(F)C2.Cc1ccccc1C(=O)Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2cc3c(cc2C)CC(F)(F)C3)cn1.O=C(Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1ccccc1F.O=C(Nc1cnc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1c(F)cccc1F
• InChI: InChI=1S/C22H17ClF2N2O.C22H19F2N3O.2C21H13ClF4N2O.C21H14ClF3N2O.C20H12ClF4N3O.C18H17ClF2N2O.C18H19F2N3O/c1-13-4-2-3-5-17(13)21(28)27-20-7-6-14(12-26-20)18-8-15-10-22(24,25)11-16(15)9-19(18)23;1-13-5-3-4-6-17(13)21(28)27-20-12-25-19(11-26-20)18-8-16-10-22(23,24)9-15(16)7-14(18)2;2*22-15-7-13-9-21(25,26)8-12(13)6-14(15)11-4-5-18(27-10-11)28-20(29)19-16(23)2-1-3-17(19)24;22-17-8-14-10-21(24,25)9-13(14)7-16(17)12-5-6-19(26-11-12)27-20(28)15-3-1-2-4-18(15)23;21-13-5-11-7-20(24,25)6-10(11)4-12(13)16-8-27-17(9-26-16)28-19(29)18-14(22)2-1-3-15(18)23;1-10(2)17(24)23-16-4-3-11(9-22-16)14-5-12-7-18(20,21)8-13(12)6-15(14)19;1-10(2)17(24)23-16-9-21-15(8-22-16)14-5-13-7-18(19,20)6-12(13)4-11(14)3/h2-9,12H,10-11H2,1H3,(H,26,27,28);3-8,11-12H,9-10H2,1-2H3,(H,26,27,28);2*1-7,10H,8-9H2,(H,27,28,29);1-8,11H,9-10H2,(H,26,27,28);1-5,8-9H,6-7H2,(H,27,28,29);3-6,9-10H,7-8H2,1-2H3,(H,22,23,24);4-5,8-10H,6-7H2,1-3H3,(H,22,23,24)
• InChIKey: HJBNDEGFFYIMCE-UHFFFAOYSA-N
• XLogP: 40.88
• TPSA: 374.59 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 19
• Rotatable Bonds: 24
• Heavy Atoms: 219
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3126.58
LogP ≤ 5	40.88
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	19

Frequently Asked Questions

What is the IUPAC name of N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide?

The IUPAC name of N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide (CID 158494190) is N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide.

What is the SMILES notation for N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide?

The canonical SMILES for N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide is CC(C)C(=O)Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1.Cc1cc2c(cc1-c1cnc(NC(=O)C(C)C)cn1)CC(F)(F)C2.Cc1ccccc1C(=O)Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2cc3c(cc2C)CC(F)(F)C3)cn1.O=C(Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1ccccc1F.O=C(Nc1cnc(-c2cc3c(cc2Cl)CC(F)(F)C3)cn1)c1c(F)cccc1F.

What is the InChIKey of N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide?

The InChIKey is HJBNDEGFFYIMCE-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H17ClF2N2O.C22H19F2N3O.2C21H13ClF4N2O.C21H14ClF3N2O.C20H12ClF4N3O.C18H17ClF2N2O.C18H19F2N3O/c1-13-4-2-3-5-17(13)21(28)27-20-7-6-14(12-26-20)18-8-15-10-22(24,25)11-16(15)9-19(18)23;1-13-5-3-4-6-17(13)21(28)27-20-12-25-19(11-26-20)18-8-16-10-22(23,24)9-15(16)7-14(18)2;2*22-15-7-13-9-21(25,26)8-12(13)6-14(15)11-4-5-18(27-10-11)28-20(29)19-16(23)2-1-3-17(19)24;22-17-8-14-10-21(24,25)9-13(14)7-16(17)12-5-6-19(26-11-12)27-20(28)15-3-1-2-4-18(15)23;21-13-5-11-7-20(24,25)6-10(11)4-12(13)16-8-27-17(9-26-16)28-19(29)18-14(22)2-1-3-15(18)23;1-10(2)17(24)23-16-4-3-11(9-22-16)14-5-12-7-18(20,21)8-13(12)6-15(14)19;1-10(2)17(24)23-16-9-21-15(8-22-16)14-5-13-7-18(19,20)6-12(13)4-11(14)3/h2-9,12H,10-11H2,1H3,(H,26,27,28);3-8,11-12H,9-10H2,1-2H3,(H,26,27,28);2*1-7,10H,8-9H2,(H,27,28,29);1-8,11H,9-10H2,(H,26,27,28);1-5,8-9H,6-7H2,(H,27,28,29);3-6,9-10H,7-8H2,1-2H3,(H,22,23,24);4-5,8-10H,6-7H2,1-3H3,(H,22,23,24).

What are the key properties of N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide?

N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide has a molecular weight of 3126.58 g/mol, XLogP of 40.88, 24 rotatable bonds, 8 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2,6-difluorobenzamide);N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-fluorobenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(6-chloro-2,2-difluoro-1,3-dihydroinden-5-yl)-2-pyridinyl]-2-methylpropanamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylbenzamide;N-[5-(2,2-difluoro-6-methyl-1,3-dihydroinden-5-yl)pyrazin-2-yl]-2-methylpropanamide is sourced from PubChem (CID 158494190), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).