8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine

C67H65F3N16O3 — CID 158496447

About 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine

8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine (PubChem CID 158496447) has the molecular formula C67H65F3N16O3 and a molecular weight of 1199.36 g/mol. Its IUPAC name is 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

• Compound Name: 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine
• PubChem CID: 158496447
• Molecular Formula: C67H65F3N16O3
• Molecular Weight: 1199.36 g/mol
• Exact Mass: 1198.54
• IUPAC Name: 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine
• SMILES: Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)ccn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(CN(C)C)cc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccnn3C)c2n1
• InChI: InChI=1S/C25H26FN5O.C22H20FN5O.C20H19FN6O/c1-16-14-31-24(29-16)20(18-6-4-17(5-7-18)15-30(2)3)12-27-25(31)28-13-21-19-10-11-32-23(19)9-8-22(21)26;1-13-9-15(5-7-24-13)17-10-25-22(28-12-14(2)27-21(17)28)26-11-18-16-6-8-29-20(16)4-3-19(18)23;1-12-11-27-19(25-12)15(17-5-7-24-26(17)2)10-23-20(27)22-9-14-13-6-8-28-18(13)4-3-16(14)21/h4-9,12,14H,10-11,13,15H2,1-3H3,(H,27,28);3-5,7,9-10,12H,6,8,11H2,1-2H3,(H,25,26);3-5,7,10-11H,6,8-9H2,1-2H3,(H,22,23)
• InChIKey: HJIUKARVVDZYCP-UHFFFAOYSA-N
• XLogP: 11.67
• TPSA: 188.30 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 19
• Rotatable Bonds: 14
• Heavy Atoms: 89
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1199.36
LogP ≤ 5	11.67
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	19

Frequently Asked Questions

What is the IUPAC name of 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The IUPAC name of 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine (CID 158496447) is 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine.

What is the SMILES notation for 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The canonical SMILES for 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine is Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)ccn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(CN(C)C)cc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccnn3C)c2n1.

What is the InChIKey of 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The InChIKey is HJIUKARVVDZYCP-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H26FN5O.C22H20FN5O.C20H19FN6O/c1-16-14-31-24(29-16)20(18-6-4-17(5-7-18)15-30(2)3)12-27-25(31)28-13-21-19-10-11-32-23(19)9-8-22(21)26;1-13-9-15(5-7-24-13)17-10-25-22(28-12-14(2)27-21(17)28)26-11-18-16-6-8-29-20(16)4-3-19(18)23;1-12-11-27-19(25-12)15(17-5-7-24-26(17)2)10-23-20(27)22-9-14-13-6-8-28-18(13)4-3-16(14)21/h4-9,12,14H,10-11,13,15H2,1-3H3,(H,27,28);3-5,7,9-10,12H,6,8,11H2,1-2H3,(H,25,26);3-5,7,10-11H,6,8-9H2,1-2H3,(H,22,23).

What are the key properties of 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 1199.36 g/mol, XLogP of 11.67, 14 rotatable bonds, 3 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for 8-[4-[(dimethylamino)methyl]phenyl]-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methylpyrazol-3-yl)imidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 158496447), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).