4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine

C117H111ClF2N30O3S — CID 158508934

About 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine

4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine (PubChem CID 158508934) has the molecular formula C117H111ClF2N30O3S and a molecular weight of 2090.90 g/mol. Its IUPAC name is 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine.

Molecular Properties

• Compound Name: 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine
• PubChem CID: 158508934
• Molecular Formula: C117H111ClF2N30O3S
• Molecular Weight: 2090.90 g/mol
• Exact Mass: 2088.88
• IUPAC Name: 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine
• SMILES: Cc1ccc(NC(=O)C2CCC(c3nc(-c4cc5ccccc5[nH]4)c4c(N)nccn34)CC2)c(C)n1.Cn1ccc2ccc(-c3nc(C4CCC4)n4ccnc(N)c34)c(F)c21.Nc1nccn2c(C3CCC(C(=O)Nc4cccc(F)c4)CC3)nc(-c3cc4ccccc4[nH]3)c12.Nc1nccn2c(C3CCC(C(=O)Nc4cnccn4)CC3)nc(-c3cc4ccccc4[nH]3)c12.Nc1nccn2c(C3CCC3)nc(-c3cc4cccc(Cl)c4s3)c12
• InChI: InChI=1S/C28H29N7O.C27H25FN6O.C25H24N8O.C19H18FN5.C18H15ClN4S/c1-16-7-12-21(17(2)31-16)33-28(36)19-10-8-18(9-11-19)27-34-24(25-26(29)30-13-14-35(25)27)23-15-20-5-3-4-6-22(20)32-23;28-19-5-3-6-20(15-19)31-27(35)17-10-8-16(9-11-17)26-33-23(24-25(29)30-12-13-34(24)26)22-14-18-4-1-2-7-21(18)32-22;26-23-22-21(19-13-17-3-1-2-4-18(17)30-19)32-24(33(22)12-11-29-23)15-5-7-16(8-6-15)25(34)31-20-14-27-9-10-28-20;1-24-9-7-11-5-6-13(14(20)16(11)24)15-17-18(21)22-8-10-25(17)19(23-15)12-3-2-4-12;19-12-6-2-5-11-9-13(24-16(11)12)14-15-17(20)21-7-8-23(15)18(22-14)10-3-1-4-10/h3-7,12-15,18-19,32H,8-11H2,1-2H3,(H2,29,30)(H,33,36);1-7,12-17,32H,8-11H2,(H2,29,30)(H,31,35);1-4,9-16,30H,5-8H2,(H2,26,29)(H,28,31,34);5-10,12H,2-4H2,1H3,(H2,21,22);2,5-10H,1,3-4H2,(H2,20,21)
• InChIKey: HKURMGDWPZAGSX-UHFFFAOYSA-N
• XLogP: 24.05
• TPSA: 459.32 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 28
• Rotatable Bonds: 16
• Heavy Atoms: 154
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2090.90
LogP ≤ 5	24.05
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	28

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'dyes5A(27)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine?

The IUPAC name of 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine (CID 158508934) is 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine.

What is the SMILES notation for 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine?

The canonical SMILES for 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine is Cc1ccc(NC(=O)C2CCC(c3nc(-c4cc5ccccc5[nH]4)c4c(N)nccn34)CC2)c(C)n1.Cn1ccc2ccc(-c3nc(C4CCC4)n4ccnc(N)c34)c(F)c21.Nc1nccn2c(C3CCC(C(=O)Nc4cccc(F)c4)CC3)nc(-c3cc4ccccc4[nH]3)c12.Nc1nccn2c(C3CCC(C(=O)Nc4cnccn4)CC3)nc(-c3cc4ccccc4[nH]3)c12.Nc1nccn2c(C3CCC3)nc(-c3cc4cccc(Cl)c4s3)c12.

What is the InChIKey of 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine?

The InChIKey is HKURMGDWPZAGSX-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H29N7O.C27H25FN6O.C25H24N8O.C19H18FN5.C18H15ClN4S/c1-16-7-12-21(17(2)31-16)33-28(36)19-10-8-18(9-11-19)27-34-24(25-26(29)30-13-14-35(25)27)23-15-20-5-3-4-6-22(20)32-23;28-19-5-3-6-20(15-19)31-27(35)17-10-8-16(9-11-17)26-33-23(24-25(29)30-12-13-34(24)26)22-14-18-4-1-2-7-21(18)32-22;26-23-22-21(19-13-17-3-1-2-4-18(17)30-19)32-24(33(22)12-11-29-23)15-5-7-16(8-6-15)25(34)31-20-14-27-9-10-28-20;1-24-9-7-11-5-6-13(14(20)16(11)24)15-17-18(21)22-8-10-25(17)19(23-15)12-3-2-4-12;19-12-6-2-5-11-9-13(24-16(11)12)14-15-17(20)21-7-8-23(15)18(22-14)10-3-1-4-10/h3-7,12-15,18-19,32H,8-11H2,1-2H3,(H2,29,30)(H,33,36);1-7,12-17,32H,8-11H2,(H2,29,30)(H,31,35);1-4,9-16,30H,5-8H2,(H2,26,29)(H,28,31,34);5-10,12H,2-4H2,1H3,(H2,21,22);2,5-10H,1,3-4H2,(H2,20,21).

What are the key properties of 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine?

4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine has a molecular weight of 2090.90 g/mol, XLogP of 24.05, 16 rotatable bonds, 11 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2,6-dimethyl-3-pyridinyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(3-fluorophenyl)cyclohexane-1-carboxamide;4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrazin-2-ylcyclohexane-1-carboxamide;1-(7-chloro-1-benzothiophen-2-yl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine;3-cyclobutyl-1-(7-fluoro-1-methylindol-6-yl)imidazo[1,5-a]pyrazin-8-amine is sourced from PubChem (CID 158508934), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).