1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea

C143H137FN42O16 — CID 158511869

About 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea

1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea (PubChem CID 158511869) has the molecular formula C143H137FN42O16 and a molecular weight of 2718.94 g/mol. Its IUPAC name is 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea.

Molecular Properties

• Compound Name: 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea
• PubChem CID: 158511869
• Molecular Formula: C143H137FN42O16
• Molecular Weight: 2718.94 g/mol
• Exact Mass: 2717.12
• IUPAC Name: 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea
• SMILES: CCNC(=O)Nc1ccc2ncc(-c3ccc(C(C)=O)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(CO)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(OC)c(C=O)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(OCc4ccccc4)c(F)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc4c(c3)CCO4)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3cccc(N)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccccc3N)nc2n1.O=C(NCC(O)CO)Nc1ccc2ncc(-c3ccccc3)nc2n1
• InChI: InChI=1S/C23H20FN5O2.C18H17N5O3.2C18H17N5O2.C17H17N5O3.C17H17N5O2.2C16H16N6O/c1-2-25-23(30)29-21-11-9-18-22(28-21)27-19(13-26-18)16-8-10-20(17(24)12-16)31-14-15-6-4-3-5-7-15;1-3-19-18(25)23-16-7-5-13-17(22-16)21-14(9-20-13)11-4-6-15(26-2)12(8-11)10-24;1-2-19-18(24)23-16-6-4-13-17(22-16)21-14(10-20-13)11-3-5-15-12(9-11)7-8-25-15;1-3-19-18(25)23-16-9-8-14-17(22-16)21-15(10-20-14)13-6-4-12(5-7-13)11(2)24;23-10-12(24)8-19-17(25)22-15-7-6-13-16(21-15)20-14(9-18-13)11-4-2-1-3-5-11;1-2-18-17(24)22-15-8-7-13-16(21-15)20-14(9-19-13)12-5-3-11(10-23)4-6-12;1-2-18-16(23)22-14-7-6-12-15(21-14)20-13(9-19-12)10-4-3-5-11(17)8-10;1-2-18-16(23)22-14-8-7-12-15(21-14)20-13(9-19-12)10-5-3-4-6-11(10)17/h3-13H,2,14H2,1H3,(H2,25,27,28,29,30);4-10H,3H2,1-2H3,(H2,19,21,22,23,25);3-6,9-10H,2,7-8H2,1H3,(H2,19,21,22,23,24);4-10H,3H2,1-2H3,(H2,19,21,22,23,25);1-7,9,12,23-24H,8,10H2,(H2,19,20,21,22,25);3-9,23H,2,10H2,1H3,(H2,18,20,21,22,24);2*3-9H,2,17H2,1H3,(H2,18,20,21,22,23)
• InChIKey: HLDUAFMXIJKJBL-UHFFFAOYSA-N
• XLogP: 21.33
• TPSA: 812.96 Ų
• H-Bond Donors: 21
• H-Bond Acceptors: 42
• Rotatable Bonds: 33
• Heavy Atoms: 202
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2718.94
LogP ≤ 5	21.33
H-Bond Donors ≤ 5	21
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'aldehyde', 'substructure': 'N/A'}, {'alert_name': 'aniline', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea?

The IUPAC name of 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea (CID 158511869) is 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea.

What is the SMILES notation for 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea?

The canonical SMILES for 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea is CCNC(=O)Nc1ccc2ncc(-c3ccc(C(C)=O)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(CO)cc3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(OC)c(C=O)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc(OCc4ccccc4)c(F)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccc4c(c3)CCO4)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3cccc(N)c3)nc2n1.CCNC(=O)Nc1ccc2ncc(-c3ccccc3N)nc2n1.O=C(NCC(O)CO)Nc1ccc2ncc(-c3ccccc3)nc2n1.

What is the InChIKey of 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea?

The InChIKey is HLDUAFMXIJKJBL-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H20FN5O2.C18H17N5O3.2C18H17N5O2.C17H17N5O3.C17H17N5O2.2C16H16N6O/c1-2-25-23(30)29-21-11-9-18-22(28-21)27-19(13-26-18)16-8-10-20(17(24)12-16)31-14-15-6-4-3-5-7-15;1-3-19-18(25)23-16-7-5-13-17(22-16)21-14(9-20-13)11-4-6-15(26-2)12(8-11)10-24;1-2-19-18(24)23-16-6-4-13-17(22-16)21-14(10-20-13)11-3-5-15-12(9-11)7-8-25-15;1-3-19-18(25)23-16-9-8-14-17(22-16)21-15(10-20-14)13-6-4-12(5-7-13)11(2)24;23-10-12(24)8-19-17(25)22-15-7-6-13-16(21-15)20-14(9-18-13)11-4-2-1-3-5-11;1-2-18-17(24)22-15-8-7-13-16(21-15)20-14(9-19-13)12-5-3-11(10-23)4-6-12;1-2-18-16(23)22-14-7-6-12-15(21-14)20-13(9-19-12)10-4-3-5-11(17)8-10;1-2-18-16(23)22-14-8-7-12-15(21-14)20-13(9-19-12)10-5-3-4-6-11(10)17/h3-13H,2,14H2,1H3,(H2,25,27,28,29,30);4-10H,3H2,1-2H3,(H2,19,21,22,23,25);3-6,9-10H,2,7-8H2,1H3,(H2,19,21,22,23,24);4-10H,3H2,1-2H3,(H2,19,21,22,23,25);1-7,9,12,23-24H,8,10H2,(H2,19,20,21,22,25);3-9,23H,2,10H2,1H3,(H2,18,20,21,22,24);2*3-9H,2,17H2,1H3,(H2,18,20,21,22,23).

What are the key properties of 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea?

1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea has a molecular weight of 2718.94 g/mol, XLogP of 21.33, 33 rotatable bonds, 21 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[3-(4-acetylphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(3-aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-[3-(2,3-dihydro-1-benzofuran-5-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea;1-(2,3-dihydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea;1-ethyl-3-[3-(3-fluoro-4-phenylmethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-(3-formyl-4-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea;1-ethyl-3-[3-[4-(hydroxymethyl)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea is sourced from PubChem (CID 158511869), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).