N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide

C122H103F2N31O7 — CID 158518020

IUPACN-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
SMILESCN(C)C(=O)Nc1cncc(-c2ccc3[nH]nc(C(=O)Nc4ccc(C#N)cc4)c3c2)c1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)CC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCCC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCOCC5)c4)cc23)cc1
InChIInChI=1S/C26H22F2N6O.C25H22N6O.C24H20N6O2.C24H20N6O.C23H19N7O2/c27-26(28)7-9-34(10-8-26)16-18-11-20(15-30-14-18)19-3-6-23-22(12-19)24(33-32-23)25(35)31-21-4-1-17(13-29)2-5-21;26-14-17-4-7-20(8-5-17)28-25(32)24-22-13-18(6-9-23(22)29-30-24)19-12-21(16-27-15-19)31-10-2-1-3-11-31;25-13-16-1-4-19(5-2-16)27-24(31)23-21-12-17(3-6-22(21)28-29-23)18-11-20(15-26-14-18)30-7-9-32-10-8-30;25-13-16-3-6-19(7-4-16)27-24(31)23-21-12-17(5-8-22(21)28-29-23)18-11-20(15-26-14-18)30-9-1-2-10-30;1-30(2)23(32)27-18-9-16(12-25-13-18)15-5-8-20-19(10-15)21(29-28-20)22(31)26-17-6-3-14(11-24)4-7-17/h1-6,11-12,14-15H,7-10,16H2,(H,31,35)(H,32,33);4-9,12-13,15-16H,1-3,10-11H2,(H,28,32)(H,29,30);1-6,11-12,14-15H,7-10H2,(H,27,31)(H,28,29);3-8,11-12,14-15H,1-2,9-10H2,(H,27,31)(H,28,29);3-10,12-13H,1-2H3,(H,26,31)(H,27,32)(H,28,29)
InChIKeyHLWGMBNNVSTSSJ-UHFFFAOYSA-N
MW2153.37 g/mol
LogP21.50
Rot. Bonds21

About N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide

N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide (PubChem CID 158518020) has the molecular formula C122H103F2N31O7 and a molecular weight of 2153.37 g/mol. Its IUPAC name is N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide.

Molecular Properties

Compound NameN-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
PubChem CID158518020
Molecular FormulaC122H103F2N31O7
Molecular Weight2153.37 g/mol
Exact Mass2151.86
IUPAC NameN-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
SMILESCN(C)C(=O)Nc1cncc(-c2ccc3[nH]nc(C(=O)Nc4ccc(C#N)cc4)c3c2)c1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)CC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCCC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCOCC5)c4)cc23)cc1
InChIInChI=1S/C26H22F2N6O.C25H22N6O.C24H20N6O2.C24H20N6O.C23H19N7O2/c27-26(28)7-9-34(10-8-26)16-18-11-20(15-30-14-18)19-3-6-23-22(12-19)24(33-32-23)25(35)31-21-4-1-17(13-29)2-5-21;26-14-17-4-7-20(8-5-17)28-25(32)24-22-13-18(6-9-23(22)29-30-24)19-12-21(16-27-15-19)31-10-2-1-3-11-31;25-13-16-1-4-19(5-2-16)27-24(31)23-21-12-17(3-6-22(21)28-29-23)18-11-20(15-26-14-18)30-7-9-32-10-8-30;25-13-16-3-6-19(7-4-16)27-24(31)23-21-12-17(5-8-22(21)28-29-23)18-11-20(15-26-14-18)30-9-1-2-10-30;1-30(2)23(32)27-18-9-16(12-25-13-18)15-5-8-20-19(10-15)21(29-28-20)22(31)26-17-6-3-14(11-24)4-7-17/h1-6,11-12,14-15H,7-10,16H2,(H,31,35)(H,32,33);4-9,12-13,15-16H,1-3,10-11H2,(H,28,32)(H,29,30);1-6,11-12,14-15H,7-10H2,(H,27,31)(H,28,29);3-8,11-12,14-15H,1-2,9-10H2,(H,27,31)(H,28,29);3-10,12-13H,1-2H3,(H,26,31)(H,27,32)(H,28,29)
InChIKeyHLWGMBNNVSTSSJ-UHFFFAOYSA-N
XLogP21.50
TPSA526.83 Ų
H-Bond Donors11
H-Bond Acceptors26
Rotatable Bonds21
Heavy Atoms162
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002153.37
LogP ≤ 521.50
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1026

Analyze N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide with MolForge

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Related Compounds

N-[5-[3-(pyridin-3-ylcarbamoyl)-1H-indazol-5-yl]-3-pyridinyl]morpholine-4-carboxamide
CID 89444817
5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]pyridin-3-yl]-N-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 89450648
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]pyridin-3-yl]-N-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 89450649
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]pyridin-3-yl]-N-[6-(2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-1H-indazole-3-carboxamide
CID 118382468
5-[1-[5-[3-carbamoyl-1-[2-[2-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)-6-methyl-4-pyridinyl]carbamoyl]-4-fluoropyrrolidin-1-yl]-2-oxoethyl]indazol-5-yl]pyridazin-3-yl]pyridazin-1-ium-4-yl]-1-[2-[4-fluoro-2-[[2-(5-methyl-3-oxopyrazolidin-1-yl)-3-pyridinyl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]indazole-3-carboxamide
CID 123927541
5-(5-fluoro-3-pyridinyl)-1-[1-[[5-[(5-pyridin-3-yl-1H-indazole-3-carbonyl)amino]-2-pyridinyl]methyl]pyrrolidin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]indazole-3-carboxamide
CID 144555306
N-[5-[6-fluoro-7-[4-[2-[6-fluoro-5-[5-(pyrrolidin-1-ylmethyl)-3-pyridinyl]-1H-indazol-3-yl]-1H-imidazo[4,5-c]pyridin-4-yl]-2-pyridinyl]-3-(4-pyridin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-5-yl]-3-pyridinyl]benzamide
CID 145034654
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(6-pyrrolidin-1-yl-3-pyridinyl)-1-[1-[5-[[5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carbonyl]amino]-2-pyridinyl]pyrrolidin-3-yl]indazole-3-carboxamide
CID 146233157
N-(2-aminopyrimidin-5-yl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1-[[5-[[5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carbonyl]amino]pyrimidin-2-yl]amino]indazole-3-carboxamide
CID 146233164
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(dimethylamino)-3-pyridinyl]-1-[[methyl-[5-[[5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carbonyl]amino]-2-pyridinyl]amino]methyl]indazole-3-carboxamide
CID 149044100
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-pyridazin-4-yl-1-[5-[[5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carbonyl]amino]pyridazin-3-yl]indazole-3-carboxamide
CID 155017803
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylpiperidin-1-yl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylpiperidin-1-yl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-methylpiperidin-1-yl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
CID 157052033

Frequently Asked Questions

What is the IUPAC name of N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?
The IUPAC name of N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide (CID 158518020) is N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide.
What is the SMILES notation for N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?
The canonical SMILES for N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide is CN(C)C(=O)Nc1cncc(-c2ccc3[nH]nc(C(=O)Nc4ccc(C#N)cc4)c3c2)c1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)CC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCCCC5)c4)cc23)cc1.N#Cc1ccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N5CCOCC5)c4)cc23)cc1.
What is the InChIKey of N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?
The InChIKey is HLWGMBNNVSTSSJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H22F2N6O.C25H22N6O.C24H20N6O2.C24H20N6O.C23H19N7O2/c27-26(28)7-9-34(10-8-26)16-18-11-20(15-30-14-18)19-3-6-23-22(12-19)24(33-32-23)25(35)31-21-4-1-17(13-29)2-5-21;26-14-17-4-7-20(8-5-17)28-25(32)24-22-13-18(6-9-23(22)29-30-24)19-12-21(16-27-15-19)31-10-2-1-3-11-31;25-13-16-1-4-19(5-2-16)27-24(31)23-21-12-17(3-6-22(21)28-29-23)18-11-20(15-26-14-18)30-7-9-32-10-8-30;25-13-16-3-6-19(7-4-16)27-24(31)23-21-12-17(5-8-22(21)28-29-23)18-11-20(15-26-14-18)30-9-1-2-10-30;1-30(2)23(32)27-18-9-16(12-25-13-18)15-5-8-20-19(10-15)21(29-28-20)22(31)26-17-6-3-14(11-24)4-7-17/h1-6,11-12,14-15H,7-10,16H2,(H,31,35)(H,32,33);4-9,12-13,15-16H,1-3,10-11H2,(H,28,32)(H,29,30);1-6,11-12,14-15H,7-10H2,(H,27,31)(H,28,29);3-8,11-12,14-15H,1-2,9-10H2,(H,27,31)(H,28,29);3-10,12-13H,1-2H3,(H,26,31)(H,27,32)(H,28,29).
What are the key properties of N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?
N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide has a molecular weight of 2153.37 g/mol, XLogP of 21.50, 21 rotatable bonds, 11 hydrogen bond donors, and 26 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-cyanophenyl)-5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-[5-(dimethylcarbamoylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(4-cyanophenyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide is sourced from PubChem (CID 158518020), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).