2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide

C130H155N31O20S5 — CID 158544363

About 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide

2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide (PubChem CID 158544363) has the molecular formula C130H155N31O20S5 and a molecular weight of 2632.20 g/mol. Its IUPAC name is 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide.

Molecular Properties

• Compound Name: 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide
• PubChem CID: 158544363
• Molecular Formula: C130H155N31O20S5
• Molecular Weight: 2632.20 g/mol
• Exact Mass: 2630.07
• IUPAC Name: 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide
• SMILES: CC(C)N(C)Cc1cccc(-c2ccc(S(=O)(=O)N3CCN(c4ncc(C(=O)NO)cn4)CC3)cc2)c1.CN(C)Cc1cccc(-c2ccc(S(=O)(=O)N3CCN(c4ncc(C(=O)NO)cn4)CC3)cc2)c1.CN1CCN(Cc2cccc(-c3ccc(S(=O)(=O)N4CCN(c5ncc(C(=O)NO)cn5)CC4)cc3)c2)CC1.O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc(-c4cccc(CCN5CCCC5)c4)cc3)CC2)nc1.O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc(-c4cccc(CN5CCCC5)c4)cc3)CC2)nc1
• InChI: InChI=1S/C27H33N7O4S.C27H32N6O4S.C26H30N6O4S.C26H32N6O4S.C24H28N6O4S/c1-31-9-11-32(12-10-31)20-21-3-2-4-23(17-21)22-5-7-25(8-6-22)39(37,38)34-15-13-33(14-16-34)27-28-18-24(19-29-27)26(35)30-36;34-26(30-35)24-19-28-27(29-20-24)32-14-16-33(17-15-32)38(36,37)25-8-6-22(7-9-25)23-5-3-4-21(18-23)10-13-31-11-1-2-12-31;33-25(29-34)23-17-27-26(28-18-23)31-12-14-32(15-13-31)37(35,36)24-8-6-21(7-9-24)22-5-3-4-20(16-22)19-30-10-1-2-11-30;1-19(2)30(3)18-20-5-4-6-22(15-20)21-7-9-24(10-8-21)37(35,36)32-13-11-31(12-14-32)26-27-16-23(17-28-26)25(33)29-34;1-28(2)17-18-4-3-5-20(14-18)19-6-8-22(9-7-19)35(33,34)30-12-10-29(11-13-30)24-25-15-21(16-26-24)23(31)27-32/h2-8,17-19,36H,9-16,20H2,1H3,(H,30,35);3-9,18-20,35H,1-2,10-17H2,(H,30,34);3-9,16-18,34H,1-2,10-15,19H2,(H,29,33);4-10,15-17,19,34H,11-14,18H2,1-3H3,(H,29,33);3-9,14-16,32H,10-13,17H2,1-2H3,(H,27,31)
• InChIKey: HOXOHIRZEMUSFV-UHFFFAOYSA-N
• XLogP: 10.75
• TPSA: 598.09 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 41
• Rotatable Bonds: 37
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2632.20
LogP ≤ 5	10.75
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	41

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide?

The IUPAC name of 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide (CID 158544363) is 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide.

What is the SMILES notation for 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide?

The canonical SMILES for 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide is CC(C)N(C)Cc1cccc(-c2ccc(S(=O)(=O)N3CCN(c4ncc(C(=O)NO)cn4)CC3)cc2)c1.CN(C)Cc1cccc(-c2ccc(S(=O)(=O)N3CCN(c4ncc(C(=O)NO)cn4)CC3)cc2)c1.CN1CCN(Cc2cccc(-c3ccc(S(=O)(=O)N4CCN(c5ncc(C(=O)NO)cn5)CC4)cc3)c2)CC1.O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc(-c4cccc(CCN5CCCC5)c4)cc3)CC2)nc1.O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc(-c4cccc(CN5CCCC5)c4)cc3)CC2)nc1.

What is the InChIKey of 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide?

The InChIKey is HOXOHIRZEMUSFV-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H33N7O4S.C27H32N6O4S.C26H30N6O4S.C26H32N6O4S.C24H28N6O4S/c1-31-9-11-32(12-10-31)20-21-3-2-4-23(17-21)22-5-7-25(8-6-22)39(37,38)34-15-13-33(14-16-34)27-28-18-24(19-29-27)26(35)30-36;34-26(30-35)24-19-28-27(29-20-24)32-14-16-33(17-15-32)38(36,37)25-8-6-22(7-9-25)23-5-3-4-21(18-23)10-13-31-11-1-2-12-31;33-25(29-34)23-17-27-26(28-18-23)31-12-14-32(15-13-31)37(35,36)24-8-6-21(7-9-24)22-5-3-4-20(16-22)19-30-10-1-2-11-30;1-19(2)30(3)18-20-5-4-6-22(15-20)21-7-9-24(10-8-21)37(35,36)32-13-11-31(12-14-32)26-27-16-23(17-28-26)25(33)29-34;1-28(2)17-18-4-3-5-20(14-18)19-6-8-22(9-7-19)35(33,34)30-12-10-29(11-13-30)24-25-15-21(16-26-24)23(31)27-32/h2-8,17-19,36H,9-16,20H2,1H3,(H,30,35);3-9,18-20,35H,1-2,10-17H2,(H,30,34);3-9,16-18,34H,1-2,10-15,19H2,(H,29,33);4-10,15-17,19,34H,11-14,18H2,1-3H3,(H,29,33);3-9,14-16,32H,10-13,17H2,1-2H3,(H,27,31).

What are the key properties of 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide?

2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide has a molecular weight of 2632.20 g/mol, XLogP of 10.75, 37 rotatable bonds, 10 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[4-[4-[3-[(dimethylamino)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-[[methyl(propan-2-yl)amino]methyl]phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(2-pyrrolidin-1-ylethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]phenyl]sulfonylpiperazin-1-yl]pyrimidine-5-carboxamide is sourced from PubChem (CID 158544363), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).