6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one

C143H105N21O7 — CID 158545203

IUPAC6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one
SMILESCc1[nH]c2nc(-c3ccccc3)c(-c3ccc4ncccc4c3)cc2c(=O)c1C#N.Cc1c(-c2cc3c(=O)cc[nH]c3nc2-c2ccccc2)ccc2ncccc12.Cc1ccnc2ccc(-c3cc4ccc(=O)[nH]c4nc3-c3ccccc3)cc12.O=c1cc(-c2ccccc2)[nH]c2nc(-c3ccco3)c(-c3ccc4nc[nH]c4c3)cc12.O=c1cc[nH]c2nc(C3CCCCC3)c(-c3ccc4ncccc4c3)cc12.O=c1ccc2cc(N3CCc4ncccc4C3)c(-c3ccccc3)nc2[nH]1
InChIInChI=1S/C25H16N4O2.C25H16N4O.2C24H17N3O.C23H21N3O.C22H18N4O/c30-22-13-20(15-5-2-1-3-6-15)28-25-18(22)12-17(24(29-25)23-7-4-10-31-23)16-8-9-19-21(11-16)27-14-26-19;1-15-21(14-26)24(30)20-13-19(17-9-10-22-18(12-17)8-5-11-27-22)23(29-25(20)28-15)16-6-3-2-4-7-16;1-15-17(9-10-21-18(15)8-5-12-25-21)19-14-20-22(28)11-13-26-24(20)27-23(19)16-6-3-2-4-7-16;1-15-11-12-25-21-9-7-17(13-19(15)21)20-14-18-8-10-22(28)26-24(18)27-23(20)16-5-3-2-4-6-16;27-21-10-12-25-23-19(21)14-18(22(26-23)15-5-2-1-3-6-15)16-8-9-20-17(13-16)7-4-11-24-20;27-20-9-8-16-13-19(26-12-10-18-17(14-26)7-4-11-23-18)21(25-22(16)24-20)15-5-2-1-3-6-15/h1-14H,(H,26,27)(H,28,29,30);2-13H,1H3,(H,28,29,30);2*2-14H,1H3,(H,26,27,28);4,7-15H,1-3,5-6H2,(H,25,26,27);1-9,11,13H,10,12,14H2,(H,24,25,27)
InChIKeyHPAIIZJGJDZNSY-UHFFFAOYSA-N
MW2229.55 g/mol
LogP29.34
Rot. Bonds13

About 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one

6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one (PubChem CID 158545203) has the molecular formula C143H105N21O7 and a molecular weight of 2229.55 g/mol. Its IUPAC name is 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one.

Molecular Properties

Compound Name6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one
PubChem CID158545203
Molecular FormulaC143H105N21O7
Molecular Weight2229.55 g/mol
Exact Mass2227.85
IUPAC Name6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one
SMILESCc1[nH]c2nc(-c3ccccc3)c(-c3ccc4ncccc4c3)cc2c(=O)c1C#N.Cc1c(-c2cc3c(=O)cc[nH]c3nc2-c2ccccc2)ccc2ncccc12.Cc1ccnc2ccc(-c3cc4ccc(=O)[nH]c4nc3-c3ccccc3)cc12.O=c1cc(-c2ccccc2)[nH]c2nc(-c3ccco3)c(-c3ccc4nc[nH]c4c3)cc12.O=c1cc[nH]c2nc(C3CCCCC3)c(-c3ccc4ncccc4c3)cc12.O=c1ccc2cc(N3CCc4ncccc4C3)c(-c3ccccc3)nc2[nH]1
InChIInChI=1S/C25H16N4O2.C25H16N4O.2C24H17N3O.C23H21N3O.C22H18N4O/c30-22-13-20(15-5-2-1-3-6-15)28-25-18(22)12-17(24(29-25)23-7-4-10-31-23)16-8-9-19-21(11-16)27-14-26-19;1-15-21(14-26)24(30)20-13-19(17-9-10-22-18(12-17)8-5-11-27-22)23(29-25(20)28-15)16-6-3-2-4-7-16;1-15-17(9-10-21-18(15)8-5-12-25-21)19-14-20-22(28)11-13-26-24(20)27-23(19)16-6-3-2-4-7-16;1-15-11-12-25-21-9-7-17(13-19(15)21)20-14-18-8-10-22(28)26-24(18)27-23(20)16-5-3-2-4-6-16;27-21-10-12-25-23-19(21)14-18(22(26-23)15-5-2-1-3-6-15)16-8-9-20-17(13-16)7-4-11-24-20;27-20-9-8-16-13-19(26-12-10-18-17(14-26)7-4-11-23-18)21(25-22(16)24-20)15-5-2-1-3-6-15/h1-14H,(H,26,27)(H,28,29,30);2-13H,1H3,(H,28,29,30);2*2-14H,1H3,(H,26,27,28);4,7-15H,1-3,5-6H2,(H,25,26,27);1-9,11,13H,10,12,14H2,(H,24,25,27)
InChIKeyHPAIIZJGJDZNSY-UHFFFAOYSA-N
XLogP29.34
TPSA407.80 Ų
H-Bond Donors7
H-Bond Acceptors21
Rotatable Bonds13
Heavy Atoms171
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002229.55
LogP ≤ 529.34
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1021

Analyze 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one with MolForge

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Launch Full Analysis

Related Compounds

2-(furan-2-yl)-6-(1-methylbenzimidazol-5-yl)-N-pyridin-3-ylquinoline-4-carboxamide
CID 60202460
6-(3H-benzimidazol-5-yl)-2-(furan-2-yl)-N-pyridin-3-ylquinoline-4-carboxamide
CID 60202490
US10894784, Example 168.03
CID 129245630
2-[3-[3-[[2-(Difluoromethyl)-7-(pyrrolidin-1-ylmethyl)pyrido[3,2-d]pyrimidin-4-yl]amino]-2-methylphenyl]-2-methylphenyl]-5-[(4-formylpiperidin-1-yl)methyl]-1,3-benzoxazole-7-carbonitrile
CID 167062518
N-[4-(furan-2-ylmethylcarbamoyl)-1H-benzimidazol-2-yl]isoquinoline-3-carboxamide
CID 58026411
Tert-butyl 1-[[7-cyano-2-[3-[3-[(3-formyl-1,7-naphthyridin-8-yl)amino]-2-methylphenyl]-2-methylphenyl]-1,3-benzoxazol-5-yl]methyl]piperidine-4-carboxylate
CID 135148334
N-[4-[4-(1H-benzimidazol-2-yl)-3-oxa-9,12-diazatricyclo[8.4.0.02,6]tetradeca-1(10),2(6),4,11,13-pentaene-9-carbonyl]phenyl]-5-methyl-2-(7-oxa-2-azaspiro[3.5]nonan-2-yl)pyridine-3-carboxamide
CID 137384488
N-[4-[4-(1H-benzimidazol-2-yl)-3-oxa-9,11-diazatricyclo[8.4.0.02,6]tetradeca-1(10),2(6),4,11,13-pentaene-9-carbonyl]phenyl]-5-methyl-2-(7-oxa-2-azaspiro[3.5]nonan-2-yl)pyridine-3-carboxamide
CID 137384549
N-[4-[4-(1H-benzimidazol-2-yl)-3-oxa-9,14-diazatricyclo[8.4.0.02,6]tetradeca-1(10),2(6),4,11,13-pentaene-9-carbonyl]phenyl]-5-methyl-2-(7-oxa-2-azaspiro[3.5]nonan-2-yl)pyridine-3-carboxamide
CID 137384682
3-(1H-imidazol-2-yl)-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-2-one
CID 137438145
3-(1H-imidazol-2-yl)-7-(5-methylfuran-2-yl)-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one
CID 137438780
2-[7-(3,4-dihydro-2H-quinolin-1-yl)-4-(1H-inden-1-yl)-2-isoquinolin-1-yl-6-quinolin-2-yl-1H-benzimidazol-5-yl]-1,3-benzoxazole
CID 141080719

Frequently Asked Questions

What is the IUPAC name of 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one?
The IUPAC name of 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one (CID 158545203) is 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one.
What is the SMILES notation for 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one?
The canonical SMILES for 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one is Cc1[nH]c2nc(-c3ccccc3)c(-c3ccc4ncccc4c3)cc2c(=O)c1C#N.Cc1c(-c2cc3c(=O)cc[nH]c3nc2-c2ccccc2)ccc2ncccc12.Cc1ccnc2ccc(-c3cc4ccc(=O)[nH]c4nc3-c3ccccc3)cc12.O=c1cc(-c2ccccc2)[nH]c2nc(-c3ccco3)c(-c3ccc4nc[nH]c4c3)cc12.O=c1cc[nH]c2nc(C3CCCCC3)c(-c3ccc4ncccc4c3)cc12.O=c1ccc2cc(N3CCc4ncccc4C3)c(-c3ccccc3)nc2[nH]1.
What is the InChIKey of 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one?
The InChIKey is HPAIIZJGJDZNSY-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H16N4O2.C25H16N4O.2C24H17N3O.C23H21N3O.C22H18N4O/c30-22-13-20(15-5-2-1-3-6-15)28-25-18(22)12-17(24(29-25)23-7-4-10-31-23)16-8-9-19-21(11-16)27-14-26-19;1-15-21(14-26)24(30)20-13-19(17-9-10-22-18(12-17)8-5-11-27-22)23(29-25(20)28-15)16-6-3-2-4-7-16;1-15-17(9-10-21-18(15)8-5-12-25-21)19-14-20-22(28)11-13-26-24(20)27-23(19)16-6-3-2-4-7-16;1-15-11-12-25-21-9-7-17(13-19(15)21)20-14-18-8-10-22(28)26-24(18)27-23(20)16-5-3-2-4-6-16;27-21-10-12-25-23-19(21)14-18(22(26-23)15-5-2-1-3-6-15)16-8-9-20-17(13-16)7-4-11-24-20;27-20-9-8-16-13-19(26-12-10-18-17(14-26)7-4-11-23-18)21(25-22(16)24-20)15-5-2-1-3-6-15/h1-14H,(H,26,27)(H,28,29,30);2-13H,1H3,(H,28,29,30);2*2-14H,1H3,(H,26,27,28);4,7-15H,1-3,5-6H2,(H,25,26,27);1-9,11,13H,10,12,14H2,(H,24,25,27).
What are the key properties of 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one?
6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one has a molecular weight of 2229.55 g/mol, XLogP of 29.34, 13 rotatable bonds, 7 hydrogen bond donors, and 21 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(3H-benzimidazol-5-yl)-7-(furan-2-yl)-2-phenyl-1H-1,8-naphthyridin-4-one;7-cyclohexyl-6-quinolin-6-yl-1H-1,8-naphthyridin-4-one;6-(7,8-dihydro-5H-1,6-naphthyridin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;2-methyl-4-oxo-7-phenyl-6-quinolin-6-yl-1H-1,8-naphthyridine-3-carbonitrile;6-(4-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-2-one;6-(5-methylquinolin-6-yl)-7-phenyl-1H-1,8-naphthyridin-4-one is sourced from PubChem (CID 158545203), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).