5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide

C249H274ClF19N84O23S2 — CID 158547794

IUPAC5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
SMILESCc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccco2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(C2CCSC2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(N2CCN(CCO)CC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(-c3cccs3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(N3CCNCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(N3CCNCC3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCCN3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCN3)c(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCN(CCO)CC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCNCC3)c2)cn1
InChIInChI=1S/C27H34FN9O3.C26H32FN9O3.C25H27F4N9O2.C25H21F4N7O2S.C25H24FN7O3.C25H28FN7O2S.C24H27ClFN9O2.C24H25F4N9O2.2C24H28FN9O2/c1-19-14-21(16-22(15-19)36-6-4-35(5-7-36)8-11-38)31-20-2-3-24(29-17-20)26(39)33-34-27-30-18-23(28)25(32-27)37-9-12-40-13-10-37;27-22-18-29-26(31-24(22)36-11-14-39-15-12-36)33-32-25(38)23-5-4-20(17-28-23)30-19-2-1-3-21(16-19)35-8-6-34(7-9-35)10-13-37;26-20-15-32-24(34-22(20)38-7-9-40-10-8-38)36-35-23(39)21-2-1-17(14-31-21)33-18-11-16(25(27,28)29)12-19(13-18)37-5-3-30-4-6-37;26-19-14-31-24(33-22(19)36-5-7-38-8-6-36)35-34-23(37)20-4-3-17(13-30-20)32-18-11-15(21-2-1-9-39-21)10-16(12-18)25(27,28)29;1-16-11-17(22-3-2-8-36-22)13-19(12-16)29-18-4-5-21(27-14-18)24(34)31-32-25-28-15-20(26)23(30-25)33-6-9-35-10-7-33;1-16-10-18(17-4-9-36-15-17)12-20(11-16)29-19-2-3-22(27-13-19)24(34)31-32-25-28-14-21(26)23(30-25)33-5-7-35-8-6-33;25-16-11-18(13-19(12-16)34-5-3-27-4-6-34)30-17-1-2-21(28-14-17)23(36)32-33-24-29-15-20(26)22(31-24)35-7-9-37-10-8-35;25-18-14-30-23(33-21(18)36-8-10-39-11-9-36)35-34-22(38)19-4-2-16(13-29-19)32-15-3-5-20(37-7-1-6-31-37)17(12-15)24(26,27)28;25-20-16-27-24(30-22(20)33-11-13-36-14-12-33)32-31-23(35)21-8-5-18(15-26-21)29-17-3-6-19(7-4-17)34-10-2-1-9-28-34;25-20-16-28-24(30-22(20)34-10-12-36-13-11-34)32-31-23(35)21-5-4-18(15-27-21)29-17-2-1-3-19(14-17)33-8-6-26-7-9-33/h2-3,14-18,31,38H,4-13H2,1H3,(H,33,39)(H,30,32,34);1-5,16-18,30,37H,6-15H2,(H,32,38)(H,29,31,33);1-2,11-15,30,33H,3-10H2,(H,35,39)(H,32,34,36);1-4,9-14,32H,5-8H2,(H,34,37)(H,31,33,35);2-5,8,11-15,29H,6-7,9-10H2,1H3,(H,31,34)(H,28,30,32);2-3,10-14,17,29H,4-9,15H2,1H3,(H,31,34)(H,28,30,32);1-2,11-15,27,30H,3-10H2,(H,32,36)(H,29,31,33);2-5,12-14,31-32H,1,6-11H2,(H,34,38)(H,30,33,35);3-8,15-16,28-29H,1-2,9-14H2,(H,31,35)(H,27,30,32);1-5,14-16,26,29H,6-13H2,(H,31,35)(H,28,30,32)
InChIKeyHPIMJDIPDKZKTM-UHFFFAOYSA-N
MW5272.05 g/mol
LogP28.60
Rot. Bonds74

About 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide

5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide (PubChem CID 158547794) has the molecular formula C249H274ClF19N84O23S2 and a molecular weight of 5272.05 g/mol. Its IUPAC name is 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide.

Molecular Properties

Compound Name5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
PubChem CID158547794
Molecular FormulaC249H274ClF19N84O23S2
Molecular Weight5272.05 g/mol
Exact Mass5268.17
IUPAC Name5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
SMILESCc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccco2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(C2CCSC2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(N2CCN(CCO)CC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(-c3cccs3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(N3CCNCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(N3CCNCC3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCCN3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCN3)c(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCN(CCO)CC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCNCC3)c2)cn1
InChIInChI=1S/C27H34FN9O3.C26H32FN9O3.C25H27F4N9O2.C25H21F4N7O2S.C25H24FN7O3.C25H28FN7O2S.C24H27ClFN9O2.C24H25F4N9O2.2C24H28FN9O2/c1-19-14-21(16-22(15-19)36-6-4-35(5-7-36)8-11-38)31-20-2-3-24(29-17-20)26(39)33-34-27-30-18-23(28)25(32-27)37-9-12-40-13-10-37;27-22-18-29-26(31-24(22)36-11-14-39-15-12-36)33-32-25(38)23-5-4-20(17-28-23)30-19-2-1-3-21(16-19)35-8-6-34(7-9-35)10-13-37;26-20-15-32-24(34-22(20)38-7-9-40-10-8-38)36-35-23(39)21-2-1-17(14-31-21)33-18-11-16(25(27,28)29)12-19(13-18)37-5-3-30-4-6-37;26-19-14-31-24(33-22(19)36-5-7-38-8-6-36)35-34-23(37)20-4-3-17(13-30-20)32-18-11-15(21-2-1-9-39-21)10-16(12-18)25(27,28)29;1-16-11-17(22-3-2-8-36-22)13-19(12-16)29-18-4-5-21(27-14-18)24(34)31-32-25-28-15-20(26)23(30-25)33-6-9-35-10-7-33;1-16-10-18(17-4-9-36-15-17)12-20(11-16)29-19-2-3-22(27-13-19)24(34)31-32-25-28-14-21(26)23(30-25)33-5-7-35-8-6-33;25-16-11-18(13-19(12-16)34-5-3-27-4-6-34)30-17-1-2-21(28-14-17)23(36)32-33-24-29-15-20(26)22(31-24)35-7-9-37-10-8-35;25-18-14-30-23(33-21(18)36-8-10-39-11-9-36)35-34-22(38)19-4-2-16(13-29-19)32-15-3-5-20(37-7-1-6-31-37)17(12-15)24(26,27)28;25-20-16-27-24(30-22(20)33-11-13-36-14-12-33)32-31-23(35)21-8-5-18(15-26-21)29-17-3-6-19(7-4-17)34-10-2-1-9-28-34;25-20-16-28-24(30-22(20)34-10-12-36-13-11-34)32-31-23(35)21-5-4-18(15-27-21)29-17-2-1-3-19(14-17)33-8-6-26-7-9-33/h2-3,14-18,31,38H,4-13H2,1H3,(H,33,39)(H,30,32,34);1-5,16-18,30,37H,6-15H2,(H,32,38)(H,29,31,33);1-2,11-15,30,33H,3-10H2,(H,35,39)(H,32,34,36);1-4,9-14,32H,5-8H2,(H,34,37)(H,31,33,35);2-5,8,11-15,29H,6-7,9-10H2,1H3,(H,31,34)(H,28,30,32);2-3,10-14,17,29H,4-9,15H2,1H3,(H,31,34)(H,28,30,32);1-2,11-15,27,30H,3-10H2,(H,32,36)(H,29,31,33);2-5,12-14,31-32H,1,6-11H2,(H,34,38)(H,30,33,35);3-8,15-16,28-29H,1-2,9-14H2,(H,31,35)(H,27,30,32);1-5,14-16,26,29H,6-13H2,(H,31,35)(H,28,30,32)
InChIKeyHPIMJDIPDKZKTM-UHFFFAOYSA-N
XLogP28.60
TPSA1185.91 Ų
H-Bond Donors37
H-Bond Acceptors99
Rotatable Bonds74
Heavy Atoms378
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005272.05
LogP ≤ 528.60
H-Bond Donors ≤ 537
H-Bond Acceptors ≤ 1099

Analyze 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
The IUPAC name of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide (CID 158547794) is 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide.
What is the SMILES notation for 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
The canonical SMILES for 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide is Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccco2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(C2CCSC2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(N2CCN(CCO)CC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(-c3cccs3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(N3CCNCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(N3CCNCC3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCCN3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCN3)c(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCN(CCO)CC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCNCC3)c2)cn1.
What is the InChIKey of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
The InChIKey is HPIMJDIPDKZKTM-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H34FN9O3.C26H32FN9O3.C25H27F4N9O2.C25H21F4N7O2S.C25H24FN7O3.C25H28FN7O2S.C24H27ClFN9O2.C24H25F4N9O2.2C24H28FN9O2/c1-19-14-21(16-22(15-19)36-6-4-35(5-7-36)8-11-38)31-20-2-3-24(29-17-20)26(39)33-34-27-30-18-23(28)25(32-27)37-9-12-40-13-10-37;27-22-18-29-26(31-24(22)36-11-14-39-15-12-36)33-32-25(38)23-5-4-20(17-28-23)30-19-2-1-3-21(16-19)35-8-6-34(7-9-35)10-13-37;26-20-15-32-24(34-22(20)38-7-9-40-10-8-38)36-35-23(39)21-2-1-17(14-31-21)33-18-11-16(25(27,28)29)12-19(13-18)37-5-3-30-4-6-37;26-19-14-31-24(33-22(19)36-5-7-38-8-6-36)35-34-23(37)20-4-3-17(13-30-20)32-18-11-15(21-2-1-9-39-21)10-16(12-18)25(27,28)29;1-16-11-17(22-3-2-8-36-22)13-19(12-16)29-18-4-5-21(27-14-18)24(34)31-32-25-28-15-20(26)23(30-25)33-6-9-35-10-7-33;1-16-10-18(17-4-9-36-15-17)12-20(11-16)29-19-2-3-22(27-13-19)24(34)31-32-25-28-14-21(26)23(30-25)33-5-7-35-8-6-33;25-16-11-18(13-19(12-16)34-5-3-27-4-6-34)30-17-1-2-21(28-14-17)23(36)32-33-24-29-15-20(26)22(31-24)35-7-9-37-10-8-35;25-18-14-30-23(33-21(18)36-8-10-39-11-9-36)35-34-22(38)19-4-2-16(13-29-19)32-15-3-5-20(37-7-1-6-31-37)17(12-15)24(26,27)28;25-20-16-27-24(30-22(20)33-11-13-36-14-12-33)32-31-23(35)21-8-5-18(15-26-21)29-17-3-6-19(7-4-17)34-10-2-1-9-28-34;25-20-16-28-24(30-22(20)34-10-12-36-13-11-34)32-31-23(35)21-5-4-18(15-27-21)29-17-2-1-3-19(14-17)33-8-6-26-7-9-33/h2-3,14-18,31,38H,4-13H2,1H3,(H,33,39)(H,30,32,34);1-5,16-18,30,37H,6-15H2,(H,32,38)(H,29,31,33);1-2,11-15,30,33H,3-10H2,(H,35,39)(H,32,34,36);1-4,9-14,32H,5-8H2,(H,34,37)(H,31,33,35);2-5,8,11-15,29H,6-7,9-10H2,1H3,(H,31,34)(H,28,30,32);2-3,10-14,17,29H,4-9,15H2,1H3,(H,31,34)(H,28,30,32);1-2,11-15,27,30H,3-10H2,(H,32,36)(H,29,31,33);2-5,12-14,31-32H,1,6-11H2,(H,34,38)(H,30,33,35);3-8,15-16,28-29H,1-2,9-14H2,(H,31,35)(H,27,30,32);1-5,14-16,26,29H,6-13H2,(H,31,35)(H,28,30,32).
What are the key properties of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide has a molecular weight of 5272.05 g/mol, XLogP of 28.60, 74 rotatable bonds, 37 hydrogen bond donors, and 99 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide is sourced from PubChem (CID 158547794), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).