5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol

C180H264F2N18O7S7 — CID 158563028

IUPAC5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol
SMILESCC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(CCCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(CCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(CCCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(CCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCN(CCCCCCO)CC4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCN(CCNCCO)CC4)n3)ccc21.CC1(C)CCC(F)(F)c2cc(-c3csc(N4CCN(CCCCCO)CC4)n3)ccc21
InChIInChI=1S/C27H41N3OS.C27H40N2OS.2C26H38N2OS.C25H38N4OS.C25H36N2OS.C24H33F2N3OS/c1-26(2)11-12-27(3,4)23-19-21(9-10-22(23)26)24-20-32-25(28-24)30-16-14-29(15-17-30)13-7-5-6-8-18-31;1-26(2)13-14-27(3,4)23-17-21(11-12-22(23)26)24-19-31-25(28-24)29-15-8-10-20(18-29)9-6-5-7-16-30;1-25(2)12-13-26(3,4)22-16-20(10-11-21(22)25)23-18-30-24(27-23)28-14-7-9-19(17-28)8-5-6-15-29;1-25(2)12-13-26(3,4)22-16-20(9-10-21(22)25)23-18-30-24(27-23)28-14-11-19(17-28)8-6-5-7-15-29;1-24(2)7-8-25(3,4)21-17-19(5-6-20(21)24)22-18-31-23(27-22)29-14-12-28(13-15-29)11-9-26-10-16-30;1-24(2)11-12-25(3,4)21-15-19(8-9-20(21)24)22-17-29-23(26-22)27-13-10-18(16-27)7-5-6-14-28;1-23(2)8-9-24(25,26)20-16-18(6-7-19(20)23)21-17-31-22(27-21)29-13-11-28(12-14-29)10-4-3-5-15-30/h9-10,19-20,31H,5-8,11-18H2,1-4H3;11-12,17,19-20,30H,5-10,13-16,18H2,1-4H3;10-11,16,18-19,29H,5-9,12-15,17H2,1-4H3;9-10,16,18-19,29H,5-8,11-15,17H2,1-4H3;5-6,17-18,26,30H,7-16H2,1-4H3;8-9,15,17-18,28H,5-7,10-14,16H2,1-4H3;6-7,16-17,30H,3-5,8-15H2,1-2H3
InChIKeyHRCVHRYCLDEDPF-UHFFFAOYSA-N
MW3054.68 g/mol
LogP41.11
Rot. Bonds48

About 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol

5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol (PubChem CID 158563028) has the molecular formula C180H264F2N18O7S7 and a molecular weight of 3054.68 g/mol. Its IUPAC name is 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol.

Molecular Properties

Compound Name5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol
PubChem CID158563028
Molecular FormulaC180H264F2N18O7S7
Molecular Weight3054.68 g/mol
Exact Mass3051.89
IUPAC Name5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol
SMILESCC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(CCCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(CCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(CCCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(CCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCN(CCCCCCO)CC4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCN(CCNCCO)CC4)n3)ccc21.CC1(C)CCC(F)(F)c2cc(-c3csc(N4CCN(CCCCCO)CC4)n3)ccc21
InChIInChI=1S/C27H41N3OS.C27H40N2OS.2C26H38N2OS.C25H38N4OS.C25H36N2OS.C24H33F2N3OS/c1-26(2)11-12-27(3,4)23-19-21(9-10-22(23)26)24-20-32-25(28-24)30-16-14-29(15-17-30)13-7-5-6-8-18-31;1-26(2)13-14-27(3,4)23-17-21(11-12-22(23)26)24-19-31-25(28-24)29-15-8-10-20(18-29)9-6-5-7-16-30;1-25(2)12-13-26(3,4)22-16-20(10-11-21(22)25)23-18-30-24(27-23)28-14-7-9-19(17-28)8-5-6-15-29;1-25(2)12-13-26(3,4)22-16-20(9-10-21(22)25)23-18-30-24(27-23)28-14-11-19(17-28)8-6-5-7-15-29;1-24(2)7-8-25(3,4)21-17-19(5-6-20(21)24)22-18-31-23(27-22)29-14-12-28(13-15-29)11-9-26-10-16-30;1-24(2)11-12-25(3,4)21-15-19(8-9-20(21)24)22-17-29-23(26-22)27-13-10-18(16-27)7-5-6-14-28;1-23(2)8-9-24(25,26)20-16-18(6-7-19(20)23)21-17-31-22(27-21)29-13-11-28(12-14-29)10-4-3-5-15-30/h9-10,19-20,31H,5-8,11-18H2,1-4H3;11-12,17,19-20,30H,5-10,13-16,18H2,1-4H3;10-11,16,18-19,29H,5-9,12-15,17H2,1-4H3;9-10,16,18-19,29H,5-8,11-15,17H2,1-4H3;5-6,17-18,26,30H,7-16H2,1-4H3;8-9,15,17-18,28H,5-7,10-14,16H2,1-4H3;6-7,16-17,30H,3-5,8-15H2,1-2H3
InChIKeyHRCVHRYCLDEDPF-UHFFFAOYSA-N
XLogP41.11
TPSA276.27 Ų
H-Bond Donors8
H-Bond Acceptors32
Rotatable Bonds48
Heavy Atoms214
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003054.68
LogP ≤ 541.11
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1032

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Analyze 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol with MolForge

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Related Compounds

6-amino-5-[4-[4-(1,1-dimethyl-2,3-dihydroinden-5-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;7-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]heptan-1-ol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;5-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]pentan-1-ol;2-[4-[4-(1,1,3,3-tetramethyl-2H-inden-5-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexane-1,6-diol
CID 157101149
(2S,3S)-2-amino-4-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]butane-1,3-diol;(1R,2S)-2-amino-1-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]propane-1,3-diol;2-[[1-[4-(5,5-dimethyl-7,8-dihydro-6H-naphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol;2-[[1-[4-(8,8-dimethyl-6,7-dihydro-5H-naphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol;4-[[1-[4-(5,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]butan-1-ol;4-[[1-[4-[(5S,8S)-5,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl]-1,3-thiazol-2-yl]piperidin-4-yl]amino]butan-1-ol;4-[[1-[4-[(5R,8S)-5,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl]-1,3-thiazol-2-yl]piperidin-4-yl]amino]butan-1-ol
CID 157061958
Ethyl 1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidine-4-carboxylate;2-(4-piperidin-4-ylpiperidin-1-yl)-4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazole;2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethanol;3-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]propane-1,2-diol;2-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]ethanamine;[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]methanamine;1-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]pyrrolidin-3-amine
CID 157124932
2-[[1-[4-(3,3-dimethyl-1,2-dihydroinden-5-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol;2-[[1-[4-(8,8-dimethyl-6,7-dihydro-5H-naphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol;4-[[1-[4-(5,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]butan-1-ol;4-[[1-[4-[(5R,8S)-5,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl]-1,3-thiazol-2-yl]piperidin-4-yl]amino]butan-1-ol;4-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]azepan-4-yl]amino]butan-1-ol;2-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]azepan-4-yl]amino]ethanol;2-[[1-[4-(1,1,3,3-tetramethyl-2H-inden-5-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol
CID 157425327
(2S)-2-amino-4-hydroxy-N-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]butanamide;2-[4-[1-[4-(5,5-dimethyl-7,8-dihydro-6H-naphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]piperazin-1-yl]ethanol;5-[2-hydroxyethyl-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]pentan-1-ol
CID 157478866
(2S,3R)-2-amino-3-hydroxy-N-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]butanamide;(2S,3R)-2-amino-3-hydroxy-1-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]butan-1-one;4-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]butan-1-ol;6-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]hexan-1-ol;5-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]pentan-1-ol;trans-(1S,2S)-2-hydroxy-N-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]cyclopentane-1-carboxamide
CID 157563355
(2S,3R)-2-amino-6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]hexane-1,3-diol;(2S,3R)-2-amino-5-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]pentane-1,3-diol;(2R,3S)-2-amino-5-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]pentane-1,3-diol;2-(1,4-diazepan-1-yl)-4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazole;2-(4-pentyl-1,4-diazepan-1-yl)-4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazole;3-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]-1,4-diazepan-1-yl]propan-1-ol;1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-amine;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol
CID 157612901
(2S,3R)-2-amino-6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]hexane-1,3-diol;(2S,3R)-2-amino-5-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]pentane-1,3-diol;(2R,3R)-2-amino-5-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]pentane-1,3-diol;(2S,3S)-2-amino-5-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]pentane-1,3-diol;(2R,3S)-2-amino-5-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]pentane-1,3-diol;2-(1,4-diazepan-1-yl)-4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazole
CID 157719817
2-[4-Aminobutyl-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol;2-[2-aminoethyl-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol;3-[2-hydroxyethyl-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]propan-1-ol;2-[2-methoxyethyl-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol
CID 157742399
4-[[1-[4-(5,5-dimethyl-7,8-dihydro-6H-naphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]butan-1-ol;1-[4-(5,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-amine;2-[[1-[4-(5,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]ethanol;1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-amine;2-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]pentane-1,5-diol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;2-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]methylamino]ethanol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol
CID 157751887
7-[2-[4-(2-Hydroxyethylamino)piperidin-1-yl]-1,3-thiazol-4-yl]-4,4-dimethyl-2,3-dihydronaphthalen-1-one;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethyl]butane-1,4-diol;2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentane-1,5-diol;[2-[[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]methyl]cyclopropyl]methanol;2-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]pentane-1,5-diol;2-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]methylamino]ethanol
CID 157752544
(3S)-3-amino-4-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]butan-1-ol;(2S)-4-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]butane-1,2-diol;(1R,2S,3R)-3-[[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]amino]cyclohexane-1,2-diol
CID 158430216

Frequently Asked Questions

What is the IUPAC name of 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol?
The IUPAC name of 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol (CID 158563028) is 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol.
What is the SMILES notation for 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol?
The canonical SMILES for 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol is CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(CCCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(CCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(CCCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(CCCCO)C4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCN(CCCCCCO)CC4)n3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCN(CCNCCO)CC4)n3)ccc21.CC1(C)CCC(F)(F)c2cc(-c3csc(N4CCN(CCCCCO)CC4)n3)ccc21.
What is the InChIKey of 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol?
The InChIKey is HRCVHRYCLDEDPF-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H41N3OS.C27H40N2OS.2C26H38N2OS.C25H38N4OS.C25H36N2OS.C24H33F2N3OS/c1-26(2)11-12-27(3,4)23-19-21(9-10-22(23)26)24-20-32-25(28-24)30-16-14-29(15-17-30)13-7-5-6-8-18-31;1-26(2)13-14-27(3,4)23-17-21(11-12-22(23)26)24-19-31-25(28-24)29-15-8-10-20(18-29)9-6-5-7-16-30;1-25(2)12-13-26(3,4)22-16-20(10-11-21(22)25)23-18-30-24(27-23)28-14-7-9-19(17-28)8-5-6-15-29;1-25(2)12-13-26(3,4)22-16-20(9-10-21(22)25)23-18-30-24(27-23)28-14-11-19(17-28)8-6-5-7-15-29;1-24(2)7-8-25(3,4)21-17-19(5-6-20(21)24)22-18-31-23(27-22)29-14-12-28(13-15-29)11-9-26-10-16-30;1-24(2)11-12-25(3,4)21-15-19(8-9-20(21)24)22-17-29-23(26-22)27-13-10-18(16-27)7-5-6-14-28;1-23(2)8-9-24(25,26)20-16-18(6-7-19(20)23)21-17-31-22(27-21)29-13-11-28(12-14-29)10-4-3-5-15-30/h9-10,19-20,31H,5-8,11-18H2,1-4H3;11-12,17,19-20,30H,5-10,13-16,18H2,1-4H3;10-11,16,18-19,29H,5-9,12-15,17H2,1-4H3;9-10,16,18-19,29H,5-8,11-15,17H2,1-4H3;5-6,17-18,26,30H,7-16H2,1-4H3;8-9,15,17-18,28H,5-7,10-14,16H2,1-4H3;6-7,16-17,30H,3-5,8-15H2,1-2H3.
What are the key properties of 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol?
5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol has a molecular weight of 3054.68 g/mol, XLogP of 41.11, 48 rotatable bonds, 8 hydrogen bond donors, and 32 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[4-[4-(8,8-difluoro-5,5-dimethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]pentan-1-ol;2-[2-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]ethylamino]ethanol;6-[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]hexan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-3-yl]pentan-1-ol;4-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]butan-1-ol;5-[1-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]pyrrolidin-3-yl]pentan-1-ol is sourced from PubChem (CID 158563028), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).