1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide

C225H320N36O26S — CID 158574976

IUPAC1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
SMILESCN(C)C(=O)CN(C)C(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CN(C)C(=O)CN1C(=O)N(CC(=O)CCCO)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cccc(S(C)(=O)=O)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cncnc1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)NC(C)(C)C(N)=O)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(CC(=O)N(C)C(C)(C)C(N)=O)C(=O)N2CC1CCC1.COc1ccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)nc1.COc1cccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1
InChIInChI=1S/C30H40N4O4S.2C30H40N4O3.C28H37N5O3.C28H43N5O3.2C27H41N5O3.C25H38N4O4/c1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)39(3,37)38;1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)37-3;1-32(2)30(24-10-5-4-6-11-24)16-14-29(15-17-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-12-13-27(37-3)19-31-25;1-31(2)28(23-7-4-3-5-8-23)13-11-26(12-14-28)19-32(18-24(34)15-22-16-29-21-30-17-22)25(35)33(26)20-27(36)9-6-10-27;1-29(2)24(34)19-31(5)25(35)20-32-21-27(33(26(32)36)18-22-10-9-11-22)14-16-28(17-15-27,30(3)4)23-12-7-6-8-13-23;1-25(2,23(28)34)29-22(33)18-31-19-26(32(24(31)35)17-20-9-8-10-20)13-15-27(16-14-26,30(3)4)21-11-6-5-7-12-21;1-25(2,23(28)34)30(4)22(33)18-31-19-26(32(24(31)35)17-20-9-8-10-20)13-15-27(29-3,16-14-26)21-11-6-5-7-12-21;1-26(2)22(32)18-29-23(33)28(17-21(31)11-8-16-30)19-24(29)12-14-25(15-13-24,27(3)4)20-9-6-5-7-10-20/h4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,10-13,19,23H,7-9,14-18,20-22H2,1-3H3;3-5,7-8,16-17,21,36H,6,9-15,18-20H2,1-2H3;6-8,12-13,22H,9-11,14-21H2,1-5H3;5-7,11-12,20H,8-10,13-19H2,1-4H3,(H2,28,34)(H,29,33);5-7,11-12,20,29H,8-10,13-19H2,1-4H3,(H2,28,34);5-7,9-10,30H,8,11-19H2,1-4H3
InChIKeyHSNWRLINBQJONG-UHFFFAOYSA-N
MW3977.33 g/mol
LogP26.05
Rot. Bonds68

About 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide

1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide (PubChem CID 158574976) has the molecular formula C225H320N36O26S and a molecular weight of 3977.33 g/mol. Its IUPAC name is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide.

Molecular Properties

Compound Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
PubChem CID158574976
Molecular FormulaC225H320N36O26S
Molecular Weight3977.33 g/mol
Exact Mass3974.45
IUPAC Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide
SMILESCN(C)C(=O)CN(C)C(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CN(C)C(=O)CN1C(=O)N(CC(=O)CCCO)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cccc(S(C)(=O)=O)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cncnc1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)NC(C)(C)C(N)=O)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(CC(=O)N(C)C(C)(C)C(N)=O)C(=O)N2CC1CCC1.COc1ccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)nc1.COc1cccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1
InChIInChI=1S/C30H40N4O4S.2C30H40N4O3.C28H37N5O3.C28H43N5O3.2C27H41N5O3.C25H38N4O4/c1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)39(3,37)38;1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)37-3;1-32(2)30(24-10-5-4-6-11-24)16-14-29(15-17-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-12-13-27(37-3)19-31-25;1-31(2)28(23-7-4-3-5-8-23)13-11-26(12-14-28)19-32(18-24(34)15-22-16-29-21-30-17-22)25(35)33(26)20-27(36)9-6-10-27;1-29(2)24(34)19-31(5)25(35)20-32-21-27(33(26(32)36)18-22-10-9-11-22)14-16-28(17-15-27,30(3)4)23-12-7-6-8-13-23;1-25(2,23(28)34)29-22(33)18-31-19-26(32(24(31)35)17-20-9-8-10-20)13-15-27(16-14-26,30(3)4)21-11-6-5-7-12-21;1-25(2,23(28)34)30(4)22(33)18-31-19-26(32(24(31)35)17-20-9-8-10-20)13-15-27(29-3,16-14-26)21-11-6-5-7-12-21;1-26(2)22(32)18-29-23(33)28(17-21(31)11-8-16-30)19-24(29)12-14-25(15-13-24,27(3)4)20-9-6-5-7-10-20/h4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,10-13,19,23H,7-9,14-18,20-22H2,1-3H3;3-5,7-8,16-17,21,36H,6,9-15,18-20H2,1-2H3;6-8,12-13,22H,9-11,14-21H2,1-5H3;5-7,11-12,20H,8-10,13-19H2,1-4H3,(H2,28,34)(H,29,33);5-7,11-12,20,29H,8-10,13-19H2,1-4H3,(H2,28,34);5-7,9-10,30H,8,11-19H2,1-4H3
InChIKeyHSNWRLINBQJONG-UHFFFAOYSA-N
XLogP26.05
TPSA662.49 Ų
H-Bond Donors6
H-Bond Acceptors39
Rotatable Bonds68
Heavy Atoms288
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003977.33
LogP ≤ 526.05
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1039

Analyze 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide (CID 158574976) is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide.
What is the SMILES notation for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The canonical SMILES for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide is CN(C)C(=O)CN(C)C(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CN(C)C(=O)CN1C(=O)N(CC(=O)CCCO)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cccc(S(C)(=O)=O)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1cncnc1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)NC(C)(C)C(N)=O)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(CC(=O)N(C)C(C)(C)C(N)=O)C(=O)N2CC1CCC1.COc1ccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)nc1.COc1cccc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1.
What is the InChIKey of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
The InChIKey is HSNWRLINBQJONG-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H40N4O4S.2C30H40N4O3.C28H37N5O3.C28H43N5O3.2C27H41N5O3.C25H38N4O4/c1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)39(3,37)38;1-32(2)30(24-11-5-4-6-12-24)17-15-29(16-18-30)22-33(28(36)34(29)20-23-9-7-10-23)21-26(35)19-25-13-8-14-27(31-25)37-3;1-32(2)30(24-10-5-4-6-11-24)16-14-29(15-17-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-12-13-27(37-3)19-31-25;1-31(2)28(23-7-4-3-5-8-23)13-11-26(12-14-28)19-32(18-24(34)15-22-16-29-21-30-17-22)25(35)33(26)20-27(36)9-6-10-27;1-29(2)24(34)19-31(5)25(35)20-32-21-27(33(26(32)36)18-22-10-9-11-22)14-16-28(17-15-27,30(3)4)23-12-7-6-8-13-23;1-25(2,23(28)34)29-22(33)18-31-19-26(32(24(31)35)17-20-9-8-10-20)13-15-27(16-14-26,30(3)4)21-11-6-5-7-12-21;1-25(2,23(28)34)30(4)22(33)18-31-19-26(32(24(31)35)17-20-9-8-10-20)13-15-27(29-3,16-14-26)21-11-6-5-7-12-21;1-26(2)22(32)18-29-23(33)28(17-21(31)11-8-16-30)19-24(29)12-14-25(15-13-24,27(3)4)20-9-6-5-7-10-20/h4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,8,11-14,23H,7,9-10,15-22H2,1-3H3;4-6,10-13,19,23H,7-9,14-18,20-22H2,1-3H3;3-5,7-8,16-17,21,36H,6,9-15,18-20H2,1-2H3;6-8,12-13,22H,9-11,14-21H2,1-5H3;5-7,11-12,20H,8-10,13-19H2,1-4H3,(H2,28,34)(H,29,33);5-7,11-12,20,29H,8-10,13-19H2,1-4H3,(H2,28,34);5-7,9-10,30H,8,11-19H2,1-4H3.
What are the key properties of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide?
1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide has a molecular weight of 3977.33 g/mol, XLogP of 26.05, 68 rotatable bonds, 6 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(5-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methoxy-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-methylsulfonyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[[2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]amino]-2-methylpropanamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[2-(dimethylamino)-2-oxoethyl]-N-methylacetamide;2-[[2-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetyl]-methylamino]-2-methylpropanamide;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyrimidin-5-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-(5-hydroxy-2-oxopentyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide is sourced from PubChem (CID 158574976), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).