(4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine

C110H131Cl8N29O4S2 — CID 158593372

About (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine

(4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine (PubChem CID 158593372) has the molecular formula C110H131Cl8N29O4S2 and a molecular weight of 2271.21 g/mol. Its IUPAC name is (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine.

Molecular Properties

• Compound Name: (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine
• PubChem CID: 158593372
• Molecular Formula: C110H131Cl8N29O4S2
• Molecular Weight: 2271.21 g/mol
• Exact Mass: 2265.79
• IUPAC Name: (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine
• SMILES: CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(N)c3Cl)c3nccn13)CC2.CO[C@@H]1C[C@@H](N)C2(CCN(c3nc(C)c(-c4cccc(Cl)c4Cl)c4nccn34)CC2)C1.CO[C@H]1C[C@@H](N)C2(CCN(c3nc(C)c(-c4cccc(Cl)c4Cl)c4nccn34)CC2)C1.CO[C@H]1C[C@@H](N)C2(CCN(c3ncc(Sc4ccnc(Cl)c4Cl)c4nccn34)CC2)C1.C[C@@H]1OCC2(CCN(c3ncc(Sc4ccnc(N)c4Cl)c4nccn34)CC2)[C@@H]1N
• InChI: InChI=1S/2C23H27Cl2N5O.C23H29ClN6.C21H24Cl2N6OS.C20H24ClN7OS/c2*1-14-19(16-4-3-5-17(24)20(16)25)21-27-8-11-30(21)22(28-14)29-9-6-23(7-10-29)13-15(31-2)12-18(23)26;1-15-19(16-5-3-6-17(25)20(16)24)21-27-11-14-30(21)22(28-15)29-12-9-23(10-13-29)8-4-7-18(23)26-2;1-30-13-10-16(24)21(11-13)3-7-28(8-4-21)20-27-12-15(19-26-6-9-29(19)20)31-14-2-5-25-18(23)17(14)22;1-12-16(22)20(11-29-12)3-7-27(8-4-20)19-26-10-14(18-25-6-9-28(18)19)30-13-2-5-24-17(23)15(13)21/h2*3-5,8,11,15,18H,6-7,9-10,12-13,26H2,1-2H3;3,5-6,11,14,18,26H,4,7-10,12-13,25H2,1-2H3;2,5-6,9,12-13,16H,3-4,7-8,10-11,24H2,1H3;2,5-6,9-10,12,16H,3-4,7-8,11,22H2,1H3,(H2,23,24)/t15-,18+;15-,18-;18-;13-,16+;12-,16+/m01100/s1
• InChIKey: HUSIDZQFTDUZHK-VQAJIWLESA-N
• XLogP: 20.92
• TPSA: 398.00 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 35
• Rotatable Bonds: 16
• Heavy Atoms: 153
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2271.21
LogP ≤ 5	20.92
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	35

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'aniline', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine?

The IUPAC name of (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine (CID 158593372) is (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine.

What is the SMILES notation for (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine?

The canonical SMILES for (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine is CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(N)c3Cl)c3nccn13)CC2.CO[C@@H]1C[C@@H](N)C2(CCN(c3nc(C)c(-c4cccc(Cl)c4Cl)c4nccn34)CC2)C1.CO[C@H]1C[C@@H](N)C2(CCN(c3nc(C)c(-c4cccc(Cl)c4Cl)c4nccn34)CC2)C1.CO[C@H]1C[C@@H](N)C2(CCN(c3ncc(Sc4ccnc(Cl)c4Cl)c4nccn34)CC2)C1.C[C@@H]1OCC2(CCN(c3ncc(Sc4ccnc(N)c4Cl)c4nccn34)CC2)[C@@H]1N.

What is the InChIKey of (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine?

The InChIKey is HUSIDZQFTDUZHK-VQAJIWLESA-N. The full InChI is InChI=1S/2C23H27Cl2N5O.C23H29ClN6.C21H24Cl2N6OS.C20H24ClN7OS/c2*1-14-19(16-4-3-5-17(24)20(16)25)21-27-8-11-30(21)22(28-14)29-9-6-23(7-10-29)13-15(31-2)12-18(23)26;1-15-19(16-5-3-6-17(25)20(16)24)21-27-11-14-30(21)22(28-15)29-12-9-23(10-13-29)8-4-7-18(23)26-2;1-30-13-10-16(24)21(11-13)3-7-28(8-4-21)20-27-12-15(19-26-6-9-29(19)20)31-14-2-5-25-18(23)17(14)22;1-12-16(22)20(11-29-12)3-7-27(8-4-20)19-26-10-14(18-25-6-9-28(18)19)30-13-2-5-24-17(23)15(13)21/h2*3-5,8,11,15,18H,6-7,9-10,12-13,26H2,1-2H3;3,5-6,11,14,18,26H,4,7-10,12-13,25H2,1-2H3;2,5-6,9,12-13,16H,3-4,7-8,10-11,24H2,1H3;2,5-6,9-10,12,16H,3-4,7-8,11,22H2,1H3,(H2,23,24)/t15-,18+;15-,18-;18-;13-,16+;12-,16+/m01100/s1.

What are the key properties of (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine?

(4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine has a molecular weight of 2271.21 g/mol, XLogP of 20.92, 16 rotatable bonds, 7 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for (4R)-8-[8-(3-amino-2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(3S,4S)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine;(2S,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine;(2R,4R)-8-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]-2-methoxy-8-azaspiro[4.5]decan-4-amine is sourced from PubChem (CID 158593372), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).