5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane

C109H81F11N16O4 — CID 158604554

IUPAC5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane
SMILESC.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)cnc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccc(F)c5F)cnc34)cnc2C)cc1.Cc1ccc(NC(=O)c2nc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ccc2C)cc1
InChIInChI=1S/C28H18F5N3O.2C27H20F2N4O.C26H19F2N5O.CH4/c1-16-7-10-18(11-8-16)35-27(37)21-14-17(9-12-22(21)28(31,32)33)19-5-3-13-36-24(15-34-26(19)36)20-4-2-6-23(29)25(20)30;1-16-8-11-18(12-9-16)31-27(34)25-17(2)10-13-22(32-25)19-6-4-14-33-23(15-30-26(19)33)20-5-3-7-21(28)24(20)29;1-16-8-10-19(11-9-16)32-27(34)22-13-18(14-30-17(22)2)20-6-4-12-33-24(15-31-26(20)33)21-5-3-7-23(28)25(21)29;1-15-6-8-18(9-7-15)32-26(34)21-12-17(13-29-16(21)2)19-10-11-31-33-23(14-30-25(19)33)20-4-3-5-22(27)24(20)28;/h2-15H,1H3,(H,35,37);3-15H,1-2H3,(H,31,34);3-15H,1-2H3,(H,32,34);3-14H,1-2H3,(H,32,34);1H4
InChIKeyHWAZRAMOXCEEMY-UHFFFAOYSA-N
MW1887.93 g/mol
LogP26.19
Rot. Bonds16

About 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane

5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane (PubChem CID 158604554) has the molecular formula C109H81F11N16O4 and a molecular weight of 1887.93 g/mol. Its IUPAC name is 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane.

Molecular Properties

Compound Name5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane
PubChem CID158604554
Molecular FormulaC109H81F11N16O4
Molecular Weight1887.93 g/mol
Exact Mass1886.65
IUPAC Name5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane
SMILESC.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)cnc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccc(F)c5F)cnc34)cnc2C)cc1.Cc1ccc(NC(=O)c2nc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ccc2C)cc1
InChIInChI=1S/C28H18F5N3O.2C27H20F2N4O.C26H19F2N5O.CH4/c1-16-7-10-18(11-8-16)35-27(37)21-14-17(9-12-22(21)28(31,32)33)19-5-3-13-36-24(15-34-26(19)36)20-4-2-6-23(29)25(20)30;1-16-8-11-18(12-9-16)31-27(34)25-17(2)10-13-22(32-25)19-6-4-14-33-23(15-30-26(19)33)20-5-3-7-21(28)24(20)29;1-16-8-10-19(11-9-16)32-27(34)22-13-18(14-30-17(22)2)20-6-4-12-33-24(15-31-26(20)33)21-5-3-7-23(28)25(21)29;1-15-6-8-18(9-7-15)32-26(34)21-12-17(13-29-16(21)2)19-10-11-31-33-23(14-30-25(19)33)20-4-3-5-22(27)24(20)28;/h2-15H,1H3,(H,35,37);3-15H,1-2H3,(H,31,34);3-15H,1-2H3,(H,32,34);3-14H,1-2H3,(H,32,34);1H4
InChIKeyHWAZRAMOXCEEMY-UHFFFAOYSA-N
XLogP26.19
TPSA237.16 Ų
H-Bond Donors4
H-Bond Acceptors16
Rotatable Bonds16
Heavy Atoms140
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001887.93
LogP ≤ 526.19
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1016

Analyze 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane with MolForge

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Related Compounds

TRK degrader CG416
CID 146410659
N-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]ethyl]-2-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazin-1-yl]acetamide
CID 146410948
2-(2,6-dioxopiperidin-3-yl)-5-[[5-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazin-1-yl]-5-oxopentyl]amino]isoindole-1,3-dione
CID 146411074
2-(2,6-dioxopiperidin-3-yl)-5-[3-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazine-1-carbonyl]azetidin-1-yl]isoindole-1,3-dione
CID 146410596
2-(2,6-dioxopiperidin-3-yl)-5-[2-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazin-1-yl]ethylamino]isoindole-1,3-dione
CID 149683645
N-[2-[4-[[[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)imidazo[1,2-a]pyridin-7-yl]piperidin-4-yl]-methylamino]methyl]cyclohexyl]pyrazolo[3,4-c]pyridin-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide
CID 168079772
6'-Fluoro-N-(6-(4-(4-fluorophenyl)-1,2-dimethyl-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)-[3,3'-bipyridine]-5-carboxamide
CID 118538629
N-(6-(4-(4-Fluorophenyl)-1,2-dimethyl-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)-2,4-dimethyl-5-(pyridin-3-yl)benzamide
CID 118538663
8-[[2-Fluoro-5-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)benzoyl]amino]-7-phenylimidazo[1,2-a]pyridine-3-carboxamide
CID 122609212
N-[4-[[4-[4-[1-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]triazol-4-yl]butanoyl]piperazin-1-yl]methyl]-3-(trifluoromethyl)phenyl]-3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide
CID 156013418
N-[4-[[4-[4-[1-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethyl]triazol-4-yl]butanoyl]piperazin-1-yl]methyl]-3-(trifluoromethyl)phenyl]-3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide
CID 156017680
4-[[6-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazin-1-yl]-6-oxohexyl]amino]-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
CID 162662408

Frequently Asked Questions

What is the IUPAC name of 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane?
The IUPAC name of 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane (CID 158604554) is 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane.
What is the SMILES notation for 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane?
The canonical SMILES for 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane is C.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)cnc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccc(F)c5F)cnc34)cnc2C)cc1.Cc1ccc(NC(=O)c2nc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ccc2C)cc1.
What is the InChIKey of 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane?
The InChIKey is HWAZRAMOXCEEMY-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H18F5N3O.2C27H20F2N4O.C26H19F2N5O.CH4/c1-16-7-10-18(11-8-16)35-27(37)21-14-17(9-12-22(21)28(31,32)33)19-5-3-13-36-24(15-34-26(19)36)20-4-2-6-23(29)25(20)30;1-16-8-11-18(12-9-16)31-27(34)25-17(2)10-13-22(32-25)19-6-4-14-33-23(15-30-26(19)33)20-5-3-7-21(28)24(20)29;1-16-8-10-19(11-9-16)32-27(34)22-13-18(14-30-17(22)2)20-6-4-12-33-24(15-31-26(20)33)21-5-3-7-23(28)25(21)29;1-15-6-8-18(9-7-15)32-26(34)21-12-17(13-29-16(21)2)19-10-11-31-33-23(14-30-25(19)33)20-4-3-5-22(27)24(20)28;/h2-15H,1H3,(H,35,37);3-15H,1-2H3,(H,31,34);3-15H,1-2H3,(H,32,34);3-14H,1-2H3,(H,32,34);1H4.
What are the key properties of 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane?
5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane has a molecular weight of 1887.93 g/mol, XLogP of 26.19, 16 rotatable bonds, 4 hydrogen bond donors, and 16 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;6-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-3-methyl-N-(4-methylphenyl)pyridine-2-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;methane is sourced from PubChem (CID 158604554), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).