3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine

C136H105F37N38O7 — CID 158616298

About 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine

3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine (PubChem CID 158616298) has the molecular formula C136H105F37N38O7 and a molecular weight of 3086.52 g/mol. Its IUPAC name is 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine.

Molecular Properties

• Compound Name: 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine
• PubChem CID: 158616298
• Molecular Formula: C136H105F37N38O7
• Molecular Weight: 3086.52 g/mol
• Exact Mass: 3084.84
• IUPAC Name: 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine
• SMILES: CC(C)Oc1ccc(-c2cn3c(C(C)(F)F)nnc3cn2)cc1.CC(C)c1nnc2cnc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(C(F)(F)F)cc3F)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(C4(C#N)CCC4)cc3)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC(F)(F)F)cc3F)cn12.CC(F)(F)c1nnc2cnc(-c3cnc(OCC(F)(F)F)c(F)c3)cn12.CCOc1ccc(-c2cn3c(C(C)(F)F)nnc3cn2)cc1.COc1cc(OC(F)(F)F)ccc1-c1cn2c(C(C)(F)F)nnc2cn1.Cc1cc(C(F)(F)F)ccc1-c1cn2c(C(C)(F)F)nnc2cn1
• InChI: InChI=1S/C18H15F2N5.C16H16F2N4O.C15H11F5N4O2.C15H11F5N4.C15H13F3N4O.C15H14F2N4O.C14H9F6N5O.C14H8F6N4O.C14H8F6N4/c1-17(19,20)16-24-23-15-9-22-14(10-25(15)16)12-3-5-13(6-4-12)18(11-21)7-2-8-18;1-10(2)23-12-6-4-11(5-7-12)13-9-22-14(8-19-13)20-21-15(22)16(3,17)18;1-14(16,17)13-23-22-12-6-21-10(7-24(12)13)9-4-3-8(5-11(9)25-2)26-15(18,19)20;1-8-5-9(15(18,19)20)3-4-10(8)11-7-24-12(6-21-11)22-23-13(24)14(2,16)17;1-9(2)14-21-20-13-7-19-12(8-22(13)14)10-3-5-11(6-4-10)23-15(16,17)18;1-3-22-11-6-4-10(5-7-11)12-9-21-13(8-18-12)19-20-14(21)15(2,16)17;1-13(16,17)12-24-23-10-4-21-9(5-25(10)12)7-2-8(15)11(22-3-7)26-6-14(18,19)20;1-13(16,17)12-23-22-11-5-21-10(6-24(11)12)8-3-2-7(4-9(8)15)25-14(18,19)20;1-13(16,17)12-23-22-11-5-21-10(6-24(11)12)8-3-2-7(4-9(8)15)14(18,19)20/h3-6,9-10H,2,7-8H2,1H3;4-10H,1-3H3;3-7H,1-2H3;3-7H,1-2H3;3-9H,1-2H3;4-9H,3H2,1-2H3;2-5H,6H2,1H3;2-6H,1H3;2-6H,1H3
• InChIKey: HXKVWGVZKJDQGK-UHFFFAOYSA-N
• XLogP: 34.07
• TPSA: 489.01 Ų
• H-Bond Acceptors: 45
• Rotatable Bonds: 29
• Heavy Atoms: 218
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3086.52
LogP ≤ 5	34.07
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	45

Frequently Asked Questions

What is the IUPAC name of 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine?

The IUPAC name of 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine (CID 158616298) is 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine.

What is the SMILES notation for 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine?

The canonical SMILES for 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine is CC(C)Oc1ccc(-c2cn3c(C(C)(F)F)nnc3cn2)cc1.CC(C)c1nnc2cnc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(C(F)(F)F)cc3F)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(C4(C#N)CCC4)cc3)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC(F)(F)F)cc3F)cn12.CC(F)(F)c1nnc2cnc(-c3cnc(OCC(F)(F)F)c(F)c3)cn12.CCOc1ccc(-c2cn3c(C(C)(F)F)nnc3cn2)cc1.COc1cc(OC(F)(F)F)ccc1-c1cn2c(C(C)(F)F)nnc2cn1.Cc1cc(C(F)(F)F)ccc1-c1cn2c(C(C)(F)F)nnc2cn1.

What is the InChIKey of 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine?

The InChIKey is HXKVWGVZKJDQGK-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H15F2N5.C16H16F2N4O.C15H11F5N4O2.C15H11F5N4.C15H13F3N4O.C15H14F2N4O.C14H9F6N5O.C14H8F6N4O.C14H8F6N4/c1-17(19,20)16-24-23-15-9-22-14(10-25(15)16)12-3-5-13(6-4-12)18(11-21)7-2-8-18;1-10(2)23-12-6-4-11(5-7-12)13-9-22-14(8-19-13)20-21-15(22)16(3,17)18;1-14(16,17)13-23-22-12-6-21-10(7-24(12)13)9-4-3-8(5-11(9)25-2)26-15(18,19)20;1-8-5-9(15(18,19)20)3-4-10(8)11-7-24-12(6-21-11)22-23-13(24)14(2,16)17;1-9(2)14-21-20-13-7-19-12(8-22(13)14)10-3-5-11(6-4-10)23-15(16,17)18;1-3-22-11-6-4-10(5-7-11)12-9-21-13(8-18-12)19-20-14(21)15(2,16)17;1-13(16,17)12-24-23-10-4-21-9(5-25(10)12)7-2-8(15)11(22-3-7)26-6-14(18,19)20;1-13(16,17)12-23-22-11-5-21-10(6-24(11)12)8-3-2-7(4-9(8)15)25-14(18,19)20;1-13(16,17)12-23-22-11-5-21-10(6-24(11)12)8-3-2-7(4-9(8)15)14(18,19)20/h3-6,9-10H,2,7-8H2,1H3;4-10H,1-3H3;3-7H,1-2H3;3-7H,1-2H3;3-9H,1-2H3;4-9H,3H2,1-2H3;2-5H,6H2,1H3;2-6H,1H3;2-6H,1H3.

What are the key properties of 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine?

3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine has a molecular weight of 3086.52 g/mol, XLogP of 34.07, 29 rotatable bonds, 0 hydrogen bond donors, and 45 hydrogen bond acceptors.

Where does this data come from?

All data for 3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine is sourced from PubChem (CID 158616298), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).