(2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide

C366H408Cl3F3N52O61S14 — CID 158624255

About (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide

(2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide (PubChem CID 158624255) has the molecular formula C366H408Cl3F3N52O61S14 and a molecular weight of 7123.88 g/mol. Its IUPAC name is (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide.

Molecular Properties

• Compound Name: (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide
• PubChem CID: 158624255
• Molecular Formula: C366H408Cl3F3N52O61S14
• Molecular Weight: 7123.88 g/mol
• Exact Mass: 7116.55
• IUPAC Name: (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide
• SMILES: CC(=O)C1(c2ccccc2)CCN(C(=O)[C@H](O)[C@@H](O)C(=O)NCCc2nc(Cc3ccccc3)cs2)CC1.CN(C)Cc1ccccc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.CN(C)c1ccccc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.CN(CCc1ccccc1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1nc(Cc2ccccc2)cs1.COc1ccc(F)cc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.Cc1cc(OCc2csc(CCNC(=O)[C@H](O)[C@@H](O)C(=O)N3CCN(c4ccccc4Cl)CC3)n2)c2ccccc2n1.Cc1ccc(F)cc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.O=C(NCCc1nc(COc2ccncc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCN(c2ccccc2Cl)CC1.O=C(NCCc1nc(Cc2ccccc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCN(c2ccccc2Cl)CC1.O=C(NCc1nc(CCc2ccccc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1.O=C(NCc1nc(Cc2ccccc2CO)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1.O=C(NCc1nc(Cc2cccnc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1.O=C(NCc1nc(Cc2ccncc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccc(F)cc1.O=C(NCc1nc(Cc2ccncc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1
• InChI: InChI=1S/C30H32ClN5O5S.C29H33N3O5S.C28H34N4O4S.C27H32N4O4S.C26H29ClN4O4S.C26H28FN3O5S.C26H28FN3O4S.C26H29N3O5S.C26H29N3O4S.C25H28ClN5O5S.C25H29N3O4S.C24H25FN4O4S.2C24H26N4O4S/c1-19-16-25(21-6-2-4-8-23(21)33-19)41-17-20-18-42-26(34-20)10-11-32-29(39)27(37)28(38)30(40)36-14-12-35(13-15-36)24-9-5-3-7-22(24)31;1-20(33)29(22-10-6-3-7-11-22)13-16-32(17-14-29)28(37)26(35)25(34)27(36)30-15-12-24-31-23(19-38-24)18-21-8-4-2-5-9-21;1-31(2)17-21-12-7-6-11-20(21)15-22-18-37-24(30-22)16-29-27(35)25(33)26(34)28(36)32-14-8-13-23(32)19-9-4-3-5-10-19;1-30(2)21-12-7-6-11-19(21)15-20-17-36-23(29-20)16-28-26(34)24(32)25(33)27(35)31-14-8-13-22(31)18-9-4-3-5-10-18;27-20-8-4-5-9-21(20)30-12-14-31(15-13-30)26(35)24(33)23(32)25(34)28-11-10-22-29-19(17-36-22)16-18-6-2-1-3-7-18;1-35-21-10-9-18(27)12-17(21)13-19-15-36-22(29-19)14-28-25(33)23(31)24(32)26(34)30-11-5-8-20(30)16-6-3-2-4-7-16;1-16-9-10-19(27)12-18(16)13-20-15-35-22(29-20)14-28-25(33)23(31)24(32)26(34)30-11-5-8-21(30)17-6-3-2-4-7-17;30-15-19-10-5-4-9-18(19)13-20-16-35-22(28-20)14-27-25(33)23(31)24(32)26(34)29-12-6-11-21(29)17-7-2-1-3-8-17;30-23(24(31)26(33)29-15-7-12-21(29)19-10-5-2-6-11-19)25(32)27-16-22-28-20(17-34-22)14-13-18-8-3-1-4-9-18;26-19-3-1-2-4-20(19)30-11-13-31(14-12-30)25(35)23(33)22(32)24(34)28-10-7-21-29-17(16-37-21)15-36-18-5-8-27-9-6-18;1-28(15-13-18-8-4-2-5-9-18)25(32)23(30)22(29)24(31)26-14-12-21-27-20(17-33-21)16-19-10-6-3-7-11-19;25-17-5-3-16(4-6-17)19-2-1-11-29(19)24(33)22(31)21(30)23(32)27-13-20-28-18(14-34-20)12-15-7-9-26-10-8-15;29-21(22(30)24(32)28-11-5-9-19(28)17-7-2-1-3-8-17)23(31)26-14-20-27-18(15-33-20)12-16-6-4-10-25-13-16;29-21(22(30)24(32)28-12-4-7-19(28)17-5-2-1-3-6-17)23(31)26-14-20-27-18(15-33-20)13-16-8-10-25-11-9-16/h2-9,16,18,27-28,37-38H,10-15,17H2,1H3,(H,32,39);2-11,19,25-26,34-35H,12-18H2,1H3,(H,30,36);3-7,9-12,18,23,25-26,33-34H,8,13-17H2,1-2H3,(H,29,35);3-7,9-12,17,22,24-25,32-33H,8,13-16H2,1-2H3,(H,28,34);1-9,17,23-24,32-33H,10-16H2,(H,28,34);2-4,6-7,9-10,12,15,20,23-24,31-32H,5,8,11,13-14H2,1H3,(H,28,33);2-4,6-7,9-10,12,15,21,23-24,31-32H,5,8,11,13-14H2,1H3,(H,28,33);1-5,7-10,16,21,23-24,30-32H,6,11-15H2,(H,27,33);1-6,8-11,17,21,23-24,30-31H,7,12-16H2,(H,27,32);1-6,8-9,16,22-23,32-33H,7,10-15H2,(H,28,34);2-11,17,22-23,29-30H,12-16H2,1H3,(H,26,31);3-10,14,19,21-22,30-31H,1-2,11-13H2,(H,27,32);1-4,6-8,10,13,15,19,21-22,29-30H,5,9,11-12,14H2,(H,26,31);1-3,5-6,8-11,15,19,21-22,29-30H,4,7,12-14H2,(H,26,31)/t27-,28-;25-,26-;23?,25-,26-;22?,24-,25-;23-,24-;20?,23-,24-;3*21?,23-,24-;2*22-,23-;3*19?,21-,22-/m11111111111111/s1
• InChIKey: HYJUOLSKLPHTKQ-SAFGVZFHSA-N
• XLogP: 31.31
• TPSA: 1584.28 Ų
• H-Bond Donors: 43
• H-Bond Acceptors: 99
• Rotatable Bonds: 128
• Heavy Atoms: 499
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	7123.88
LogP ≤ 5	31.31
H-Bond Donors ≤ 5	43
H-Bond Acceptors ≤ 10	99

Frequently Asked Questions

What is the IUPAC name of (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide?

The IUPAC name of (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide (CID 158624255) is (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide.

What is the SMILES notation for (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide?

The canonical SMILES for (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide is CC(=O)C1(c2ccccc2)CCN(C(=O)[C@H](O)[C@@H](O)C(=O)NCCc2nc(Cc3ccccc3)cs2)CC1.CN(C)Cc1ccccc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.CN(C)c1ccccc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.CN(CCc1ccccc1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1nc(Cc2ccccc2)cs1.COc1ccc(F)cc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.Cc1cc(OCc2csc(CCNC(=O)[C@H](O)[C@@H](O)C(=O)N3CCN(c4ccccc4Cl)CC3)n2)c2ccccc2n1.Cc1ccc(F)cc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccc2)n1.O=C(NCCc1nc(COc2ccncc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCN(c2ccccc2Cl)CC1.O=C(NCCc1nc(Cc2ccccc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCN(c2ccccc2Cl)CC1.O=C(NCc1nc(CCc2ccccc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1.O=C(NCc1nc(Cc2ccccc2CO)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1.O=C(NCc1nc(Cc2cccnc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1.O=C(NCc1nc(Cc2ccncc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccc(F)cc1.O=C(NCc1nc(Cc2ccncc2)cs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ccccc1.

What is the InChIKey of (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide?

The InChIKey is HYJUOLSKLPHTKQ-SAFGVZFHSA-N. The full InChI is InChI=1S/C30H32ClN5O5S.C29H33N3O5S.C28H34N4O4S.C27H32N4O4S.C26H29ClN4O4S.C26H28FN3O5S.C26H28FN3O4S.C26H29N3O5S.C26H29N3O4S.C25H28ClN5O5S.C25H29N3O4S.C24H25FN4O4S.2C24H26N4O4S/c1-19-16-25(21-6-2-4-8-23(21)33-19)41-17-20-18-42-26(34-20)10-11-32-29(39)27(37)28(38)30(40)36-14-12-35(13-15-36)24-9-5-3-7-22(24)31;1-20(33)29(22-10-6-3-7-11-22)13-16-32(17-14-29)28(37)26(35)25(34)27(36)30-15-12-24-31-23(19-38-24)18-21-8-4-2-5-9-21;1-31(2)17-21-12-7-6-11-20(21)15-22-18-37-24(30-22)16-29-27(35)25(33)26(34)28(36)32-14-8-13-23(32)19-9-4-3-5-10-19;1-30(2)21-12-7-6-11-19(21)15-20-17-36-23(29-20)16-28-26(34)24(32)25(33)27(35)31-14-8-13-22(31)18-9-4-3-5-10-18;27-20-8-4-5-9-21(20)30-12-14-31(15-13-30)26(35)24(33)23(32)25(34)28-11-10-22-29-19(17-36-22)16-18-6-2-1-3-7-18;1-35-21-10-9-18(27)12-17(21)13-19-15-36-22(29-19)14-28-25(33)23(31)24(32)26(34)30-11-5-8-20(30)16-6-3-2-4-7-16;1-16-9-10-19(27)12-18(16)13-20-15-35-22(29-20)14-28-25(33)23(31)24(32)26(34)30-11-5-8-21(30)17-6-3-2-4-7-17;30-15-19-10-5-4-9-18(19)13-20-16-35-22(28-20)14-27-25(33)23(31)24(32)26(34)29-12-6-11-21(29)17-7-2-1-3-8-17;30-23(24(31)26(33)29-15-7-12-21(29)19-10-5-2-6-11-19)25(32)27-16-22-28-20(17-34-22)14-13-18-8-3-1-4-9-18;26-19-3-1-2-4-20(19)30-11-13-31(14-12-30)25(35)23(33)22(32)24(34)28-10-7-21-29-17(16-37-21)15-36-18-5-8-27-9-6-18;1-28(15-13-18-8-4-2-5-9-18)25(32)23(30)22(29)24(31)26-14-12-21-27-20(17-33-21)16-19-10-6-3-7-11-19;25-17-5-3-16(4-6-17)19-2-1-11-29(19)24(33)22(31)21(30)23(32)27-13-20-28-18(14-34-20)12-15-7-9-26-10-8-15;29-21(22(30)24(32)28-11-5-9-19(28)17-7-2-1-3-8-17)23(31)26-14-20-27-18(15-33-20)12-16-6-4-10-25-13-16;29-21(22(30)24(32)28-12-4-7-19(28)17-5-2-1-3-6-17)23(31)26-14-20-27-18(15-33-20)13-16-8-10-25-11-9-16/h2-9,16,18,27-28,37-38H,10-15,17H2,1H3,(H,32,39);2-11,19,25-26,34-35H,12-18H2,1H3,(H,30,36);3-7,9-12,18,23,25-26,33-34H,8,13-17H2,1-2H3,(H,29,35);3-7,9-12,17,22,24-25,32-33H,8,13-16H2,1-2H3,(H,28,34);1-9,17,23-24,32-33H,10-16H2,(H,28,34);2-4,6-7,9-10,12,15,20,23-24,31-32H,5,8,11,13-14H2,1H3,(H,28,33);2-4,6-7,9-10,12,15,21,23-24,31-32H,5,8,11,13-14H2,1H3,(H,28,33);1-5,7-10,16,21,23-24,30-32H,6,11-15H2,(H,27,33);1-6,8-11,17,21,23-24,30-31H,7,12-16H2,(H,27,32);1-6,8-9,16,22-23,32-33H,7,10-15H2,(H,28,34);2-11,17,22-23,29-30H,12-16H2,1H3,(H,26,31);3-10,14,19,21-22,30-31H,1-2,11-13H2,(H,27,32);1-4,6-8,10,13,15,19,21-22,29-30H,5,9,11-12,14H2,(H,26,31);1-3,5-6,8-11,15,19,21-22,29-30H,4,7,12-14H2,(H,26,31)/t27-,28-;25-,26-;23?,25-,26-;22?,24-,25-;23-,24-;20?,23-,24-;3*21?,23-,24-;2*22-,23-;3*19?,21-,22-/m11111111111111/s1.

What are the key properties of (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide?

(2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide has a molecular weight of 7123.88 g/mol, XLogP of 31.31, 128 rotatable bonds, 43 hydrogen bond donors, and 99 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,3R)-4-(4-acetyl-4-phenylpiperidin-1-yl)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[2-(4-benzyl-1,3-thiazol-2-yl)ethyl]-2,3-dihydroxy-N'-methyl-N'-(2-phenylethyl)butanediamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-N-[2-[4-[(2-methylquinolin-4-yl)oxymethyl]-1,3-thiazol-2-yl]ethyl]-4-oxobutanamide;(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-[2-[4-(pyridin-4-yloxymethyl)-1,3-thiazol-2-yl]ethyl]butanamide;(2R,3R)-2,3-dihydroxy-N-[[4-[[2-(hydroxymethyl)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenylethyl)-1,3-thiazol-2-yl]methyl]-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-3-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide;(2R,3R)-N-[[4-[[2-[(dimethylamino)methyl]phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[[2-(dimethylamino)phenyl]methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methoxyphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-N-[[4-[(5-fluoro-2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide;(2R,3R)-4-[2-(4-fluorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[[4-(pyridin-4-ylmethyl)-1,3-thiazol-2-yl]methyl]butanamide is sourced from PubChem (CID 158624255), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).