6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine

C93H65Cl2F5N24O — CID 158630805

About 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine

6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine (PubChem CID 158630805) has the molecular formula C93H65Cl2F5N24O and a molecular weight of 1700.61 g/mol. Its IUPAC name is 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine.

Molecular Properties

• Compound Name: 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine
• PubChem CID: 158630805
• Molecular Formula: C93H65Cl2F5N24O
• Molecular Weight: 1700.61 g/mol
• Exact Mass: 1698.51
• IUPAC Name: 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine
• SMILES: CN1CCC(n2cc(-c3cncc(-c4cc(-c5cc(Cl)ccc5F)nc5nccnc45)c3)cn2)CC1.Cn1cc(-c2cncc(-c3cc(-c4ccccc4F)nc4nccnc34)c2)cn1.Fc1ccc(Cl)cc1-c1cc(-c2cncc3ncccc23)c2nccnc2n1.OCCn1cc(-c2cncc(-c3cc(-c4cc(F)ccc4F)nc4nccnc34)c2)cn1
• InChI: InChI=1S/C27H23ClFN7.C23H16F2N6O.C22H15FN6.C21H11ClFN5/c1-35-8-4-21(5-9-35)36-16-19(15-33-36)17-10-18(14-30-13-17)22-12-25(23-11-20(28)2-3-24(23)29)34-27-26(22)31-6-7-32-27;24-17-1-2-20(25)19(8-17)21-9-18(22-23(30-21)28-4-3-27-22)15-7-14(10-26-11-15)16-12-29-31(13-16)5-6-32;1-29-13-16(12-27-29)14-8-15(11-24-10-14)18-9-20(17-4-2-3-5-19(17)23)28-22-21(18)25-6-7-26-22;22-12-3-4-17(23)15(8-12)18-9-14(20-21(28-18)27-7-6-26-20)16-10-24-11-19-13(16)2-1-5-25-19/h2-3,6-7,10-16,21H,4-5,8-9H2,1H3;1-4,7-13,32H,5-6H2;2-13H,1H3;1-11H
• InChIKey: HZEBIMKOEJUPLR-UHFFFAOYSA-N
• XLogP: 18.95
• TPSA: 296.06 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 25
• Rotatable Bonds: 14
• Heavy Atoms: 125
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1700.61
LogP ≤ 5	18.95
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine?

The IUPAC name of 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine (CID 158630805) is 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine.

What is the SMILES notation for 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine?

The canonical SMILES for 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine is CN1CCC(n2cc(-c3cncc(-c4cc(-c5cc(Cl)ccc5F)nc5nccnc45)c3)cn2)CC1.Cn1cc(-c2cncc(-c3cc(-c4ccccc4F)nc4nccnc34)c2)cn1.Fc1ccc(Cl)cc1-c1cc(-c2cncc3ncccc23)c2nccnc2n1.OCCn1cc(-c2cncc(-c3cc(-c4cc(F)ccc4F)nc4nccnc34)c2)cn1.

What is the InChIKey of 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine?

The InChIKey is HZEBIMKOEJUPLR-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H23ClFN7.C23H16F2N6O.C22H15FN6.C21H11ClFN5/c1-35-8-4-21(5-9-35)36-16-19(15-33-36)17-10-18(14-30-13-17)22-12-25(23-11-20(28)2-3-24(23)29)34-27-26(22)31-6-7-32-27;24-17-1-2-20(25)19(8-17)21-9-18(22-23(30-21)28-4-3-27-22)15-7-14(10-26-11-15)16-12-29-31(13-16)5-6-32;1-29-13-16(12-27-29)14-8-15(11-24-10-14)18-9-20(17-4-2-3-5-19(17)23)28-22-21(18)25-6-7-26-22;22-12-3-4-17(23)15(8-12)18-9-14(20-21(28-18)27-7-6-26-20)16-10-24-11-19-13(16)2-1-5-25-19/h2-3,6-7,10-16,21H,4-5,8-9H2,1H3;1-4,7-13,32H,5-6H2;2-13H,1H3;1-11H.

What are the key properties of 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine?

6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine has a molecular weight of 1700.61 g/mol, XLogP of 18.95, 14 rotatable bonds, 1 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(5-chloro-2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;6-(5-chloro-2-fluorophenyl)-8-(1,7-naphthyridin-5-yl)pyrido[2,3-b]pyrazine;2-[4-[5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-3-pyridinyl]pyrazol-1-yl]ethanol;6-(2-fluorophenyl)-8-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]pyrido[2,3-b]pyrazine is sourced from PubChem (CID 158630805), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).