6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one

C153H134N38O14S — CID 158661415

IUPAC6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one
SMILESC=CC(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CC/C=C/C(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CCC(=O)NCCOc1ccc2ncnc(Nc3ccc(Oc4ccc5c(c4)ncn5C)c(C)c3)c2c1.CCS(=O)(=O)c1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.Cc1cc(Nc2ncnc3ccc(OCC4CC4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1nnc(Cc2ccc3ncnc(Nc4ccc(Oc5ccn6ncnc6c5)c(C)c4)c3c2)o1
InChIInChI=1S/C28H28N6O3.C27H24N6O2.C25H20N8O2.C25H22N6O2.C25H20N6O2.C23H20N6O3S/c1-4-27(35)29-11-12-36-20-6-8-23-22(14-20)28(31-16-30-23)33-19-5-10-26(18(2)13-19)37-21-7-9-25-24(15-21)32-17-34(25)3;1-3-4-5-21(34)13-19-6-8-24-23(14-19)27(30-16-28-24)32-20-7-9-25(18(2)12-20)35-22-10-11-33-26(15-22)29-17-31-33;1-15-9-18(4-6-22(15)35-19-7-8-33-23(12-19)27-14-29-33)30-25-20-10-17(3-5-21(20)26-13-28-25)11-24-32-31-16(2)34-24;1-16-10-18(4-7-23(16)33-20-8-9-31-24(12-20)27-15-29-31)30-25-21-11-19(32-13-17-2-3-17)5-6-22(21)26-14-28-25;1-3-19(32)11-17-4-6-22-21(12-17)25(28-14-26-22)30-18-5-7-23(16(2)10-18)33-20-8-9-31-24(13-20)27-15-29-31;1-3-33(30,31)18-5-6-20-19(12-18)23(26-13-24-20)28-16-4-7-21(15(2)10-16)32-17-8-9-29-22(11-17)25-14-27-29/h5-10,13-17H,4,11-12H2,1-3H3,(H,29,35)(H,30,31,33);4-12,14-17H,3,13H2,1-2H3,(H,28,30,32);3-10,12-14H,11H2,1-2H3,(H,26,28,30);4-12,14-15,17H,2-3,13H2,1H3,(H,26,28,30);3-10,12-15H,1,11H2,2H3,(H,26,28,30);4-14H,3H2,1-2H3,(H,24,26,28)/b;5-4+;;;;
InChIKeyICUNTIXRROVSNF-LPJJUMOJSA-N
MW2761.07 g/mol
LogP30.09
Rot. Bonds43

About 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one

6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one (PubChem CID 158661415) has the molecular formula C153H134N38O14S and a molecular weight of 2761.07 g/mol. Its IUPAC name is 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one.

Molecular Properties

Compound Name6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one
PubChem CID158661415
Molecular FormulaC153H134N38O14S
Molecular Weight2761.07 g/mol
Exact Mass2759.07
IUPAC Name6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one
SMILESC=CC(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CC/C=C/C(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CCC(=O)NCCOc1ccc2ncnc(Nc3ccc(Oc4ccc5c(c4)ncn5C)c(C)c3)c2c1.CCS(=O)(=O)c1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.Cc1cc(Nc2ncnc3ccc(OCC4CC4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1nnc(Cc2ccc3ncnc(Nc4ccc(Oc5ccn6ncnc6c5)c(C)c4)c3c2)o1
InChIInChI=1S/C28H28N6O3.C27H24N6O2.C25H20N8O2.C25H22N6O2.C25H20N6O2.C23H20N6O3S/c1-4-27(35)29-11-12-36-20-6-8-23-22(14-20)28(31-16-30-23)33-19-5-10-26(18(2)13-19)37-21-7-9-25-24(15-21)32-17-34(25)3;1-3-4-5-21(34)13-19-6-8-24-23(14-19)27(30-16-28-24)32-20-7-9-25(18(2)12-20)35-22-10-11-33-26(15-22)29-17-31-33;1-15-9-18(4-6-22(15)35-19-7-8-33-23(12-19)27-14-29-33)30-25-20-10-17(3-5-21(20)26-13-28-25)11-24-32-31-16(2)34-24;1-16-10-18(4-7-23(16)33-20-8-9-31-24(12-20)27-15-29-31)30-25-21-11-19(32-13-17-2-3-17)5-6-22(21)26-14-28-25;1-3-19(32)11-17-4-6-22-21(12-17)25(28-14-26-22)30-18-5-7-23(16(2)10-18)33-20-8-9-31-24(13-20)27-15-29-31;1-3-33(30,31)18-5-6-20-19(12-18)23(26-13-24-20)28-16-4-7-21(15(2)10-16)32-17-8-9-29-22(11-17)25-14-27-29/h5-10,13-17H,4,11-12H2,1-3H3,(H,29,35)(H,30,31,33);4-12,14-17H,3,13H2,1-2H3,(H,28,30,32);3-10,12-14H,11H2,1-2H3,(H,26,28,30);4-12,14-15,17H,2-3,13H2,1H3,(H,26,28,30);3-10,12-15H,1,11H2,2H3,(H,26,28,30);4-14H,3H2,1-2H3,(H,24,26,28)/b;5-4+;;;;
InChIKeyICUNTIXRROVSNF-LPJJUMOJSA-N
XLogP30.09
TPSA605.77 Ų
H-Bond Donors7
H-Bond Acceptors51
Rotatable Bonds43
Heavy Atoms206
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002761.07
LogP ≤ 530.09
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1051

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

Analyze 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one with MolForge

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Related Compounds

N-(2-amino-2-methylpropyl)-N-methyl-2-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]acetamide;4-cyclopropyl-1-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]butan-2-one;6-[(5,5-difluoro-4,6-dihydro-1H-pyrimidin-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;6-[(E)-3-(dimethylamino)prop-1-enyl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;6-[(4,4-dimethyl-5H-1,3-oxazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;5-hydroxy-4,4-dimethyl-1-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]pentane-2-thione;6-[5-[[methyl(2-methylsulfonylethyl)amino]methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine
CID 158146727
(E)-N-cyclopropyl-3-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]prop-2-enamide;(E)-N,N-dimethyl-3-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]prop-2-enamide;(E)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-4-[(2R)-pyrrolidin-2-yl]but-3-en-2-one;(E)-N-(2-hydroxyethyl)-3-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]prop-2-enamide;(E)-1-[4-(4-imidazo[1,2-a]pyrimidin-7-yloxy-3-methylanilino)quinazolin-6-yl]-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one
CID 157150587
6-(3-aminophenyl)-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;6-[(4,4-dimethyl-5H-1,3-oxazol-2-yl)methyl]-N-[3-methyl-4-[(8-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-7-yl)oxy]phenyl]quinazolin-4-amine;2-[4-[7-methoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]oxypiperidin-1-yl]-N-methylacetamide;2-methoxy-N-[3-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]phenyl]acetamide;N-[2-[[5-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]furan-2-yl]methylamino]ethyl]methanesulfonamide
CID 157824205
6-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;6-[5-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;6-[5-[(4-methylpiperazin-1-yl)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;6-[4-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;2-[[5-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]furan-2-yl]methylamino]ethanesulfonamide;phenyl 2-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]acetate
CID 158021899
1-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]but-3-en-2-one;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-N,N-dimethylacetamide;1-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-4-methoxy-3-methylbutan-2-one;[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-morpholin-4-ylmethanone;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(1,3,4-thiadiazol-2-ylmethyl)quinazolin-4-amine;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(1,3-thiazol-2-ylmethyl)quinazolin-4-amine
CID 158075628
CID 158320232
CID 158320232
1-[2-[4-(benzenesulfonyl)piperidin-1-yl]-2-oxoethyl]-N-(4-hydroxyphenyl)pyrrolidine-3-carboxamide;1-[2-[4-(benzotriazol-1-yl)piperidin-1-yl]-2-oxoethyl]-N-(4-hydroxyphenyl)pyrrolidine-3-carboxamide;(3S)-1-[1,1-dideuterio-2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-3-methoxy-N-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide;N-(4-hydroxyphenyl)-1-[2-[4-(4-methylbenzoyl)piperidin-1-yl]-2-oxoethyl]pyrrolidine-3-carboxamide;N-(4-hydroxyphenyl)-1-[2-[(2S)-2-methyl-4-[4-methyl-1-(quinoline-4-carbonyl)piperidin-4-yl]piperazin-1-yl]-2-oxoethyl]pyrrolidine-3-carboxamide;(3R)-N-(4-hydroxy-3-propan-2-ylphenyl)-1-[2-oxo-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]pyrrolidine-3-carboxamide
CID 158396326
(2E)-2-(cyclopropylmethylidene)-4-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-3-oxobutanenitrile;[5-[[6-[(4,4-dimethyl-5H-1,3-oxazol-2-yl)methyl]quinazolin-4-yl]amino]-2-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]methanol;1-[4-[4-[3-fluoro-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one;3-methyl-1-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;6-[3-(4-methylsulfonylbutyl)pyrrol-1-yl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]-6-(3-oxa-1-azaspiro[4.4]non-1-en-2-ylmethyl)quinazolin-4-amine;N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]-6-pyrrol-1-ylquinazolin-4-amine
CID 158420445
[(3S)-3-[(4-amino-2,2-dioxo-1H-2lambda6,3-benzothiazin-5-yl)oxymethyl]piperidin-1-yl]-(3-imidazol-1-ylphenyl)methanone;[(2R)-2-[(4-amino-2,2-dioxo-1H-2lambda6,3-benzothiazin-5-yl)oxymethyl]piperidin-1-yl]-(6-methyl-1-propan-2-ylpyrazolo[3,4-b]pyridin-4-yl)methanone;[(3S)-3-[(4-amino-2,2-dioxo-1H-2lambda6,3-benzothiazin-5-yl)oxymethyl]piperidin-1-yl]-(2-methylquinolin-4-yl)methanone;[(2R)-2-[(4-amino-2,2-dioxo-1H-2lambda6,3-benzothiazin-5-yl)oxymethyl]piperidin-1-yl]-(1,3,6-trimethylpyrazolo[3,4-b]pyridin-4-yl)methanone;[(3S)-3-[(4-amino-2,2-dioxo-1H-2lambda6,3-benzothiazin-5-yl)oxymethyl]piperidin-1-yl]-(1,3,6-trimethylpyrazolo[3,4-b]pyridin-4-yl)methanone
CID 158430123
6-[(5,5-dimethyl-1,4-dihydroimidazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;6-[(4,4-dimethyl-5H-1,3-oxazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;3-fluoro-1-[7-fluoro-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;6-[1-methyl-5-(4-methylsulfonylbutyl)pyrrol-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;N-[(E)-3-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]prop-2-enyl]cyclopropanecarboxamide
CID 158444408
6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-6-yloxy)phenyl]quinazolin-4-amine;6-(2-cyclopropyloxyethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-6-yloxy)phenyl]quinazolin-4-amine;2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]-1-(1-methylpiperidin-4-yl)ethanone;[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl] 4-methylpiperazine-1-carboxylate;N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-6-pyrazol-1-ylquinazolin-4-amine
CID 158518338
6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;3-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]propan-1-ol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol
CID 158574872

Frequently Asked Questions

What is the IUPAC name of 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one?
The IUPAC name of 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one (CID 158661415) is 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one.
What is the SMILES notation for 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one?
The canonical SMILES for 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one is C=CC(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CC/C=C/C(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CCC(=O)NCCOc1ccc2ncnc(Nc3ccc(Oc4ccc5c(c4)ncn5C)c(C)c3)c2c1.CCS(=O)(=O)c1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.Cc1cc(Nc2ncnc3ccc(OCC4CC4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1nnc(Cc2ccc3ncnc(Nc4ccc(Oc5ccn6ncnc6c5)c(C)c4)c3c2)o1.
What is the InChIKey of 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one?
The InChIKey is ICUNTIXRROVSNF-LPJJUMOJSA-N. The full InChI is InChI=1S/C28H28N6O3.C27H24N6O2.C25H20N8O2.C25H22N6O2.C25H20N6O2.C23H20N6O3S/c1-4-27(35)29-11-12-36-20-6-8-23-22(14-20)28(31-16-30-23)33-19-5-10-26(18(2)13-19)37-21-7-9-25-24(15-21)32-17-34(25)3;1-3-4-5-21(34)13-19-6-8-24-23(14-19)27(30-16-28-24)32-20-7-9-25(18(2)12-20)35-22-10-11-33-26(15-22)29-17-31-33;1-15-9-18(4-6-22(15)35-19-7-8-33-23(12-19)27-14-29-33)30-25-20-10-17(3-5-21(20)26-13-28-25)11-24-32-31-16(2)34-24;1-16-10-18(4-7-23(16)33-20-8-9-31-24(12-20)27-15-29-31)30-25-21-11-19(32-13-17-2-3-17)5-6-22(21)26-14-28-25;1-3-19(32)11-17-4-6-22-21(12-17)25(28-14-26-22)30-18-5-7-23(16(2)10-18)33-20-8-9-31-24(13-20)27-15-29-31;1-3-33(30,31)18-5-6-20-19(12-18)23(26-13-24-20)28-16-4-7-21(15(2)10-16)32-17-8-9-29-22(11-17)25-14-27-29/h5-10,13-17H,4,11-12H2,1-3H3,(H,29,35)(H,30,31,33);4-12,14-17H,3,13H2,1-2H3,(H,28,30,32);3-10,12-14H,11H2,1-2H3,(H,26,28,30);4-12,14-15,17H,2-3,13H2,1H3,(H,26,28,30);3-10,12-15H,1,11H2,2H3,(H,26,28,30);4-14H,3H2,1-2H3,(H,24,26,28)/b;5-4+;;;;.
What are the key properties of 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one?
6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one has a molecular weight of 2761.07 g/mol, XLogP of 30.09, 43 rotatable bonds, 7 hydrogen bond donors, and 51 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(cyclopropylmethoxy)-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfonyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;N-[2-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]quinazolin-6-yl]oxyethyl]propanamide;6-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]but-3-en-2-one;(E)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]hex-3-en-2-one is sourced from PubChem (CID 158661415), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).