5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine

C129H116N42O10 — CID 158669575

About 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine

5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine (PubChem CID 158669575) has the molecular formula C129H116N42O10 and a molecular weight of 2414.63 g/mol. Its IUPAC name is 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine.

Molecular Properties

• Compound Name: 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine
• PubChem CID: 158669575
• Molecular Formula: C129H116N42O10
• Molecular Weight: 2414.63 g/mol
• Exact Mass: 2412.99
• IUPAC Name: 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine
• SMILES: CC(C)(O)c1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1.COC(=O)c1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1.NC(=O)c1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5ccncn5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5cnc(N)nc5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5nccnc5N)n4)CCC3)cc2)cn1
• InChI: InChI=1S/C24H24N6O2.C23H20N6O3.C22H19N7O2.2C20H18N8O.C20H17N7O/c1-23(2,31)19-9-6-16(12-26-19)20-29-21(30-32-20)24(10-3-11-24)18-7-4-15(5-8-18)17-13-27-22(25)28-14-17;1-31-20(30)18-8-5-15(11-25-18)19-28-21(29-32-19)23(9-2-10-23)17-6-3-14(4-7-17)16-12-26-22(24)27-13-16;23-18(30)17-7-4-14(10-25-17)19-28-20(29-31-19)22(8-1-9-22)16-5-2-13(3-6-16)15-11-26-21(24)27-12-15;21-18-23-8-13(9-24-18)12-2-4-15(5-3-12)20(6-1-7-20)17-27-16(29-28-17)14-10-25-19(22)26-11-14;21-16-15(23-8-9-24-16)17-27-18(28-29-17)20(6-1-7-20)14-4-2-12(3-5-14)13-10-25-19(22)26-11-13;21-19-23-10-14(11-24-19)13-2-4-15(5-3-13)20(7-1-8-20)18-26-17(28-27-18)16-6-9-22-12-25-16/h4-9,12-14,31H,3,10-11H2,1-2H3,(H2,25,27,28);3-8,11-13H,2,9-10H2,1H3,(H2,24,26,27);2-7,10-12H,1,8-9H2,(H2,23,30)(H2,24,26,27);2-5,8-11H,1,6-7H2,(H2,21,23,24)(H2,22,25,26);2-5,8-11H,1,6-7H2,(H2,21,24)(H2,22,25,26);2-6,9-12H,1,7-8H2,(H2,21,23,24)
• InChIKey: IDTYQCICTUYZGM-UHFFFAOYSA-N
• XLogP: 18.31
• TPSA: 801.99 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 51
• Rotatable Bonds: 27
• Heavy Atoms: 181
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2414.63
LogP ≤ 5	18.31
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	51

Frequently Asked Questions

What is the IUPAC name of 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?

The IUPAC name of 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine (CID 158669575) is 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine.

What is the SMILES notation for 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?

The canonical SMILES for 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine is CC(C)(O)c1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1.COC(=O)c1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1.NC(=O)c1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5ccncn5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5cnc(N)nc5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5nccnc5N)n4)CCC3)cc2)cn1.

What is the InChIKey of 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?

The InChIKey is IDTYQCICTUYZGM-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H24N6O2.C23H20N6O3.C22H19N7O2.2C20H18N8O.C20H17N7O/c1-23(2,31)19-9-6-16(12-26-19)20-29-21(30-32-20)24(10-3-11-24)18-7-4-15(5-8-18)17-13-27-22(25)28-14-17;1-31-20(30)18-8-5-15(11-25-18)19-28-21(29-32-19)23(9-2-10-23)17-6-3-14(4-7-17)16-12-26-22(24)27-13-16;23-18(30)17-7-4-14(10-25-17)19-28-20(29-31-19)22(8-1-9-22)16-5-2-13(3-6-16)15-11-26-21(24)27-12-15;21-18-23-8-13(9-24-18)12-2-4-15(5-3-12)20(6-1-7-20)17-27-16(29-28-17)14-10-25-19(22)26-11-14;21-16-15(23-8-9-24-16)17-27-18(28-29-17)20(6-1-7-20)14-4-2-12(3-5-14)13-10-25-19(22)26-11-13;21-19-23-10-14(11-24-19)13-2-4-15(5-3-13)20(7-1-8-20)18-26-17(28-27-18)16-6-9-22-12-25-16/h4-9,12-14,31H,3,10-11H2,1-2H3,(H2,25,27,28);3-8,11-13H,2,9-10H2,1H3,(H2,24,26,27);2-7,10-12H,1,8-9H2,(H2,23,30)(H2,24,26,27);2-5,8-11H,1,6-7H2,(H2,21,23,24)(H2,22,25,26);2-5,8-11H,1,6-7H2,(H2,21,24)(H2,22,25,26);2-6,9-12H,1,7-8H2,(H2,21,23,24).

What are the key properties of 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?

5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine has a molecular weight of 2414.63 g/mol, XLogP of 18.31, 27 rotatable bonds, 10 hydrogen bond donors, and 51 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[4-[1-[5-(2-aminopyrimidin-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-amine;5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxamide;2-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]propan-2-ol;methyl 5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyridine-2-carboxylate;5-[4-[1-(5-pyrimidin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine is sourced from PubChem (CID 158669575), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).